Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Lynch, Caitlin ^a   Zhao, Jinghua ^b   Huang, Ruili ^b   Xiao, Jingwei ^a   Li, Linhao ^a   Heyward, Scott ^c   Xia, Menghang ^b   Wang, Hongbing ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Bioreclamation IVT ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B6; CYTOCHROME P450 3A; DRUG; MOLECULAR LIBRARY; PROTEIN BINDING;

CELL NUCLEUS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEP-G2 CELL LINE; HIGH THROUGHPUT SCREENING; HUMAN; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY;

CELL NUCLEUS; CYTOCHROME P-450 CYP2B6; CYTOCHROME P-450 CYP3A; GENE EXPRESSION; HEP G2 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SMALL MOLECULE LIBRARIES;

EID: 84930225408     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10405     Document Type: Article

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