Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β

Journal of Thrombosis and Haemostasis

Volumn 13, Issue 6, 2015, Pages 1139-1150

  Moroi, A J ^a   Watson, S P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

C type lectin; Glycogen synthase kinase 3; Mitogen activated protein kinases; Phosphatidylinositol 3 kinases; Protein kinase B

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; APYRASE; C TYPE LECTIN LIKE RECEPTOR 2; COLLAGEN RECEPTOR; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; GPVI PROTEIN; INDOMETACIN; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA2; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE SYK; RHODOCYTIN; RO31 8220; THROMBOXANE A2; UNCLASSIFIED DRUG; WORTMANNIN; CLEC2B PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3; LECTIN; MEMBRANE PROTEIN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; RHODOCYTIN PROTEIN, CALLOSELASMA RHODOSTOMA; SIGNAL PEPTIDE; SYK PROTEIN, HUMAN; VIPER VENOM;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE RELEASE REACTION; AGONISTS; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PHOSPHORYLATION; THROMBOCYTE; TIME FACTOR;

BLOOD PLATELETS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; PHOSPHORYLATION; PLATELET AGGREGATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SYK KINASE; TIME FACTORS; VIPER VENOMS;

EID: 84930182887     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12954     Document Type: Article

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