Inhibition of mitogen-activated protein kinase kinase does not impair primary activation of human platelets

Biochemical Journal

Volumn 318, Issue 1, 1996, Pages 207-212

  Börsch Haubold, Angelika G ^a   Kramer, Ruth M ^b   Watson, Steve P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CALCIMYCIN; COLLAGEN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL ESTER; PHOSPHOLIPASE A2; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; THROMBIN;

ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NORMAL HUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION;

EID: 0029830685     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3180207     Document Type: Article

References (33)

1. Nishida, E. and Gotoh, Y. (1993) Trends Biochem. Sci. 18, 128-131
2. Davis, R. J. (1993) J. Biol. Chem. 268, 14553-14556
3. Marshall, C. J. (1994) Curr. Opin. Genet. Dev. 4, 82-89
4. Marshall, C. J. (1995) Cell 80, 179-185
5. Lin, L.-L., Wartmann, M., Lin, A. Y., Knopf, J. L., Seth, A. and Davis, R. J. (1993) Cell 72, 269-278
6. Nemenoff, R. A., Winitz, S., Qian, N.-X., Van Putten, V., Johnson, G. L. and Heasley, L. E. (1993) J. Biol. Chem. 268, 1960-1964
7. Kramer, R. M., Roberts, E. F., Manetta, J. V., Hyslop, P. A. and Jakubowski, J. A. (1993) J. Biol. Chem. 268, 26796-26804
8. Kramer, R. M., Roberts, E. F., Hyslop, P. A., Utterback, B. G., Hui, K. Y. and Jakubowski, J. A. (1995) J. Biol. Chem. 270, 14816-14823
9. Börsch-Haubold, A. G., Kramer, R. M. and Watson, S. P. (1995) J. Biol. Chem. 270, 25885-25892
10. Siess, W. (1989) Physiol. Rev. 69, 58-178
11. Gonzalez, F. A., Raden, D. L. and Davis, R. J. (1991) J. Biol. Chem. 266, 22159-22163
12. Qiu, Z.-H. and Leslie, C. C. (1994) J. Biol. Chem. 269, 19480-19487
13. Durstin, M., Durstin, S., Molski, T. F., Becker, E. L. and Sha'afi, R. I. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 3142-3146
14. Xing, M., Wilkins, P. L., McConnell, B. K. and Mattera, R. (1994) J. Biol. Chem. 269, 3117-3124
15. Xu, X.-X., Rock, C. O., Qiu, Z.-H., Leslie, C. C. and Jackowski, S. (1994) J. Biol. Chem. 269, 31693-31700
16. Sa, G., Murugesan, G., Jaye, M., Ivashchenko, Y. and Fox, P. L. (1995) J. Biol. Chem. 270, 2360-2366
17. Ambs, P., Baccarini, M., Fitzke, E. and Dieter, P. (1995) Biochem. J. 311, 189-195
18. Waterman, A. H. and Sha'afi, R. I. (1995) Biochem. Biophys. Res. Commun. 209, 271-278
19. Fouda, S. I., Molski, T. F. P., Ashour, M. S.-E. and Sha'afi, R. I. (1995) Biochem. J. 308, 815-822
20. Pang, L., Sawada, T., Decker, S. J. and Saltiel, A. R. (1995) J. Biol. Chem. 270, 13585-13588
21. Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J. and Saltiel, A. R. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7685-7689
22. Alessi, D. R., Cohen, P., Ashworth, A., Cowley, S., Leevers, S. J. and Marshall, C. J. (1995) Methods Enzymol. 255, 279-290
23. Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T. and Saltiel, A. R. (1995) J. Biol. Chem. 270, 27489-27494
24. Nishizuka, Y. (1984) Nature (London) 308, 693-698
25. Tyers, M., Rachubinski, R. A., Stewart, M. I., Varriochio, A. M., Shorr, R. G. L., Haslam, R. J. and Harley, C. B. (1988) Nature (London) 333, 470-473
26. Kocher, M. and Clemetson, K. J. (1991) Biochem. J. 275, 301-306
27. Lin, L.-L., Lin, A. Y. and DeWitt, D. L. (1992) J. Biol. Chem. 267, 23451-23454
28. Halenda, S. P., Zavoico, G. B. and Feinstein, M. B. (1985) J. Biol. Chem. 260, 12484-12491
29. Lazar, D. F., Wiese, R. J., Brady, M. J., Mastick, C. C., Waters, S. B., Yamauchi, K., Pessin, J. E., Cuatrecasas, P. and Saltiel, A. R. (1995) J. Biol. Chem. 270, 20801-20807
30. Gould, G. W., Cuenda, A., Thomson, F. J. and Cohen, P. (1995) Biochem. J. 311, 735-738
31. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dal, T., Rubie, E. A., Ahmad, M. F., Avruch, J. and Woodgett, J. R. (1994) Nature (London) 369, 156-160
32. Han, J., Lee, J.-D., Bibbs, L. and Ulevitch, R. J. (1994) Science 265, 808-811
33. Kramer, R. M., Roberts, E. F., Strifler, B. A. and Johnstone, E. M. (1995) J. Biol. Chem. 270, 27395-27398