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Volumn 59, Issue 6, 2015, Pages 1053-1062

Curcumin induces apoptotic cell death via Oct4 inhibition and GSK-3β activation in NCCIT cells

Author keywords

Apoptotic cell death; Cancer chemoprevention; Curcumin; Oct4; Wnt catenin signaling

Indexed keywords

BETA CATENIN; CURCUMIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; OCTAMER TRANSCRIPTION FACTOR 4; POU5F1 PROTEIN, HUMAN; SMALL INTERFERING RNA;

EID: 84930181383     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201400739     Document Type: Article
Times cited : (30)

References (47)
  • 1
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh, Y. J., Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer 2003, 3, 768-780.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 2
    • 0021934758 scopus 로고
    • Chemoprevention of cancer
    • Wattenberg, L. W., Chemoprevention of cancer. Cancer Res. 1985, 45, 1-8.
    • (1985) Cancer Res , vol.45 , pp. 1-8
    • Wattenberg, L.W.1
  • 3
    • 0025352402 scopus 로고
    • A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
    • Rosner, M. H., Vigano, M. A., Ozato, K., Timmons, P. M. et al., A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 1990, 345, 686-692.
    • (1990) Nature , vol.345 , pp. 686-692
    • Rosner, M.H.1    Vigano, M.A.2    Ozato, K.3    Timmons, P.M.4
  • 4
    • 55149099432 scopus 로고    scopus 로고
    • Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling
    • Matoba, R., Niwa, H., Masui, S., Ohtsuka, S. et al., Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS One 2006, 1, e26.
    • (2006) PLoS One , vol.1 , pp. e26
    • Matoba, R.1    Niwa, H.2    Masui, S.3    Ohtsuka, S.4
  • 5
    • 0032008045 scopus 로고    scopus 로고
    • Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation
    • Pesce, M., Wang, X., Wolgemuth, D. J., Scholer, H., Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation. Mech. Dev. 1998, 71, 89-98.
    • (1998) Mech. Dev. , vol.71 , pp. 89-98
    • Pesce, M.1    Wang, X.2    Wolgemuth, D.J.3    Scholer, H.4
  • 6
    • 84872832415 scopus 로고    scopus 로고
    • OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion
    • Dai, X., Ge, J., Wang, X., Qian, X. et al., OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion. Oncol. Rep. 2013, 29, 155-160.
    • (2013) Oncol. Rep. , vol.29 , pp. 155-160
    • Dai, X.1    Ge, J.2    Wang, X.3    Qian, X.4
  • 7
    • 84857935029 scopus 로고    scopus 로고
    • OCT4 expression enhances features of cancer stem cells in a mouse model of breast cancer
    • Kim, R. J., Nam, J. S., OCT4 expression enhances features of cancer stem cells in a mouse model of breast cancer. Lab. Anim. Res. 2011, 27, 147-152.
    • (2011) Lab. Anim. Res. , vol.27 , pp. 147-152
    • Kim, R.J.1    Nam, J.S.2
  • 8
    • 79952821476 scopus 로고    scopus 로고
    • A role for OCT4 in tumor initiation of drug-resistant prostate cancer cells
    • Linn, D. E., Yang, X., Sun, F., Xie, Y. et al., A role for OCT4 in tumor initiation of drug-resistant prostate cancer cells. Genes Cancer 2010, 1, 908-916.
    • (2010) Genes Cancer , vol.1 , pp. 908-916
    • Linn, D.E.1    Yang, X.2    Sun, F.3    Xie, Y.4
  • 9
    • 84883828891 scopus 로고    scopus 로고
    • Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells
    • Lu, Y., Zhu, H., Shan, H., Lu, J. et al., Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells. Cancer Lett. 2013, 340, 113-123.
    • (2013) Cancer Lett , vol.340 , pp. 113-123
    • Lu, Y.1    Zhu, H.2    Shan, H.3    Lu, J.4
  • 10
    • 84882590291 scopus 로고    scopus 로고
    • OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway
    • Wang, Y. D., Cai, N., Wu, X. L., Cao, H. Z. et al., OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathway. Cell Death Dis. 2013, 4, e760.
    • (2013) Cell Death Dis , vol.4 , pp. e760
    • Wang, Y.D.1    Cai, N.2    Wu, X.L.3    Cao, H.Z.4
  • 11
    • 53049104709 scopus 로고    scopus 로고
    • Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis
    • Hu, T., Liu, S., Breiter, D. R., Wang, F. et al., Octamer 4 small interfering RNA results in cancer stem cell-like cell apoptosis. Cancer Res. 2008, 68, 6533-6540.
    • (2008) Cancer Res , vol.68 , pp. 6533-6540
    • Hu, T.1    Liu, S.2    Breiter, D.R.3    Wang, F.4
  • 12
    • 0030978351 scopus 로고    scopus 로고
    • beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle, H., Bauer, A., Stappert, J., Kispert, A., Kemler, R., beta-catenin is a target for the ubiquitin-proteasome pathway. Embo. J. 1997, 16, 3797-3804.
    • (1997) Embo. J. , vol.16 , pp. 3797-3804
    • Aberle, H.1    Bauer, A.2    Stappert, J.3    Kispert, A.4    Kemler, R.5
  • 13
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus, A., Birchmeier, W., Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 2008, 8, 387-398.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 14
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz, A., Nusse, R., Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 1998, 14, 59-88.
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 15
    • 41649089525 scopus 로고    scopus 로고
    • Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling
    • Malanchi, I., Peinado, H., Kassen, D., Hussenet, T. et al., Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature 2008, 452, 650-653.
    • (2008) Nature , vol.452 , pp. 650-653
    • Malanchi, I.1    Peinado, H.2    Kassen, D.3    Hussenet, T.4
  • 16
    • 84857063792 scopus 로고    scopus 로고
    • Oct4 was a novel target of Wnt signaling pathway
    • Li, J., Li, J., Chen, B., Oct4 was a novel target of Wnt signaling pathway. Mol. Cell Biochem. 2012, 362, 233-240.
    • (2012) Mol. Cell Biochem. , vol.362 , pp. 233-240
    • Li, J.1    Li, J.2    Chen, B.3
  • 17
    • 79551594937 scopus 로고    scopus 로고
    • beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
    • Kelly, K. F., Ng, D. Y., Jayakumaran, G., Wood, G. A. et al., beta-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell 2011, 8, 214-227.
    • (2011) Cell Stem Cell , vol.8 , pp. 214-227
    • Kelly, K.F.1    Ng, D.Y.2    Jayakumaran, G.3    Wood, G.A.4
  • 18
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • Takebe, N., Harris, P. J., Warren, R. Q., Ivy, S. P., Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat. Rev. Clin. Oncol. 2011, 8, 97-106.
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 19
    • 0035174504 scopus 로고    scopus 로고
    • Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions
    • Cheng, A. L., Hsu, C. H., Lin, J. K., Hsu, M. M. et al., Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res. 2001, 21, 2895-2900.
    • (2001) Anticancer Res , vol.21 , pp. 2895-2900
    • Cheng, A.L.1    Hsu, C.H.2    Lin, J.K.3    Hsu, M.M.4
  • 21
    • 84883318030 scopus 로고    scopus 로고
    • The role of cancer stem cells in the anti-carcinogenicity of curcumin
    • Norris, L., Karmokar, A., Howells, L., Steward, W. P. et al., The role of cancer stem cells in the anti-carcinogenicity of curcumin. Mol. Nutr. Food Res. 2013, 57, 1630-1637.
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1630-1637
    • Norris, L.1    Karmokar, A.2    Howells, L.3    Steward, W.P.4
  • 22
    • 33845930820 scopus 로고    scopus 로고
    • The human OCT-4 isoforms differ in their ability to confer self-renewal
    • Lee, J., Kim, H. K., Rho, J. Y., Han, Y. M., Kim, J., The human OCT-4 isoforms differ in their ability to confer self-renewal. J. Biol. Chem. 2006, 281, 33554-33565.
    • (2006) J. Biol. Chem. , vol.281 , pp. 33554-33565
    • Lee, J.1    Kim, H.K.2    Rho, J.Y.3    Han, Y.M.4    Kim, J.5
  • 23
    • 70449379202 scopus 로고    scopus 로고
    • Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2
    • Lee, S. B., Kim, C. Y., Lee, H. J., Yun, J. H., Nho, C. W., Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2. Planta. Med. 2009, 75, 1314-1318.
    • (2009) Planta. Med. , vol.75 , pp. 1314-1318
    • Lee, S.B.1    Kim, C.Y.2    Lee, H.J.3    Yun, J.H.4    Nho, C.W.5
  • 24
    • 69849105847 scopus 로고    scopus 로고
    • Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway
    • Kang, K., Lee, S. B., Jung, S. H., Cha, K. H. et al., Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway. Mol. Cells 2009, 27, 351-357.
    • (2009) Mol. Cells , vol.27 , pp. 351-357
    • Kang, K.1    Lee, S.B.2    Jung, S.H.3    Cha, K.H.4
  • 25
    • 36849020464 scopus 로고    scopus 로고
    • The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme
    • Kang, K., Lee, H. J., Kim, C. Y., Lee, S. B. et al., The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme. Biol. Pharm. Bull. 2007, 30, 2352-2359.
    • (2007) Biol. Pharm. Bull. , vol.30 , pp. 2352-2359
    • Kang, K.1    Lee, H.J.2    Kim, C.Y.3    Lee, S.B.4
  • 26
    • 84873081971 scopus 로고    scopus 로고
    • Nuclear factor-E2 (Nrf2) is regulated through the differential activation of ERK1/2 and PKC alpha/betaII by Gymnasterkoreayne B
    • Lee, K. M., Kang, K., Lee, S. B., Nho, C. W., Nuclear factor-E2 (Nrf2) is regulated through the differential activation of ERK1/2 and PKC alpha/betaII by Gymnasterkoreayne B. Cancer Lett. 2013, 330, 225-232.
    • (2013) Cancer Lett. , vol.330 , pp. 225-232
    • Lee, K.M.1    Kang, K.2    Lee, S.B.3    Nho, C.W.4
  • 27
    • 34249800943 scopus 로고    scopus 로고
    • Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal
    • Greber, B., Lehrach, H., Adjaye, J., Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal. BMC Dev. Biol. 2007, 7, 46.
    • (2007) BMC Dev. Biol. , vol.7 , pp. 46
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 28
    • 0036195104 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl
    • Anto, R. J., Mukhopadhyay, A., Denning, K., Aggarwal, B. B., Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis 2002, 23, 143-150.
    • (2002) Carcinogenesis , vol.23 , pp. 143-150
    • Anto, R.J.1    Mukhopadhyay, A.2    Denning, K.3    Aggarwal, B.B.4
  • 29
    • 84883009685 scopus 로고    scopus 로고
    • Bifunctional chemopreventive effects of Adenocaulon himalaicum through induction of detoxification enzymes and apoptosis
    • Yun, J. H., Lee, S. B., Kang, K., Lee, E. H. et al., Bifunctional chemopreventive effects of Adenocaulon himalaicum through induction of detoxification enzymes and apoptosis. J. Med. Food. 2013, 16, 701-710.
    • (2013) J. Med. Food. , vol.16 , pp. 701-710
    • Yun, J.H.1    Lee, S.B.2    Kang, K.3    Lee, E.H.4
  • 30
    • 38349004471 scopus 로고    scopus 로고
    • Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin
    • Guo, Y., Mantel, C., Hromas, R. A., Broxmeyer, H. E., Oct-4 is critical for survival/antiapoptosis of murine embryonic stem cells subjected to stress: effects associated with Stat3/survivin. Stem Cells 2008, 26, 30-34.
    • (2008) Stem Cells , vol.26 , pp. 30-34
    • Guo, Y.1    Mantel, C.2    Hromas, R.A.3    Broxmeyer, H.E.4
  • 31
    • 84876079364 scopus 로고    scopus 로고
    • Oct-4 is required for an antiapoptotic behavior of chemoresistant colorectal cancer cells enriched for cancer stem cells: effects associated with STAT3/Survivin
    • Wen, K., Fu, Z., Wu, X., Feng, J. et al., Oct-4 is required for an antiapoptotic behavior of chemoresistant colorectal cancer cells enriched for cancer stem cells: effects associated with STAT3/Survivin. Cancer Lett. 2013, 333, 56-65.
    • (2013) Cancer Lett , vol.333 , pp. 56-65
    • Wen, K.1    Fu, Z.2    Wu, X.3    Feng, J.4
  • 32
    • 33748299477 scopus 로고    scopus 로고
    • The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways
    • Beurel, E., Jope, R. S., The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways. Prog. Neurobiol. 2006, 79, 173-189.
    • (2006) Prog. Neurobiol. , vol.79 , pp. 173-189
    • Beurel, E.1    Jope, R.S.2
  • 33
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean, M., Fojo, T., Bates, S., Tumour stem cells and drug resistance. Nat. Rev. Cancer 2005, 5, 275-284.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 34
    • 70349638289 scopus 로고    scopus 로고
    • Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
    • Zhou, B. B., Zhang, H., Damelin, M., Geles, K. G. et al., Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat. Rev. Drug Discov. 2009, 8, 806-823.
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 806-823
    • Zhou, B.B.1    Zhang, H.2    Damelin, M.3    Geles, K.G.4
  • 35
    • 84869206625 scopus 로고    scopus 로고
    • Attributes of Oct4 in stem cell biology: perspectives on cancer stem cells of the ovary
    • Samardzija, C., Quinn, M., Findlay, J. K., Ahmed, N., Attributes of Oct4 in stem cell biology: perspectives on cancer stem cells of the ovary. J. Ovarian Res. 2012, 5, 37.
    • (2012) J. Ovarian Res. , vol.5 , pp. 37
    • Samardzija, C.1    Quinn, M.2    Findlay, J.K.3    Ahmed, N.4
  • 36
    • 84910010333 scopus 로고    scopus 로고
    • Transcription factor OCT4 promotes cell cycle progression by regulating CCND1 expression in esophageal carcinoma
    • Li, Z., Li, X., Li, C., Su, Y. et al., Transcription factor OCT4 promotes cell cycle progression by regulating CCND1 expression in esophageal carcinoma. Cancer Lett. 2014, 354, 77-86.
    • (2014) Cancer Lett , vol.354 , pp. 77-86
    • Li, Z.1    Li, X.2    Li, C.3    Su, Y.4
  • 37
    • 80051563653 scopus 로고    scopus 로고
    • Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca2+ influx in breast cancer cells
    • Hu, J., Qin, K., Zhang, Y., Gong, J. et al., Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca2+ influx in breast cancer cells. Biochem. Biophys. Res. Commun. 2011, 411, 786-791.
    • (2011) Biochem. Biophys. Res. Commun. , vol.411 , pp. 786-791
    • Hu, J.1    Qin, K.2    Zhang, Y.3    Gong, J.4
  • 38
    • 84908004021 scopus 로고    scopus 로고
    • Overexpression of Oct4 suppresses the metastatic potential of breast cancer cells via Rnd1 downregulation
    • Shen, L., Qin, K., Wang, D., Zhang, Y. et al., Overexpression of Oct4 suppresses the metastatic potential of breast cancer cells via Rnd1 downregulation. Biochim. Biophys. Acta 2014, 1842, 2087-2095.
    • (2014) Biochim. Biophys. Acta , vol.1842 , pp. 2087-2095
    • Shen, L.1    Qin, K.2    Wang, D.3    Zhang, Y.4
  • 39
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipid-modified and can act as stem cell growth factors
    • Willert, K., Brown, J. D., Danenberg, E., Duncan, A. W. et al., Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 2003, 423, 448-452.
    • (2003) Nature , vol.423 , pp. 448-452
    • Willert, K.1    Brown, J.D.2    Danenberg, E.3    Duncan, A.W.4
  • 40
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: a review of programmed cell death
    • Elmore, S., Apoptosis: a review of programmed cell death. Toxicol. Pathol. 2007, 35, 495-516.
    • (2007) Toxicol. Pathol. , vol.35 , pp. 495-516
    • Elmore, S.1
  • 41
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li, H., Zhu, H., Xu, C. J., Yuan, J., Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998, 94, 491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 42
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: preclinical and clinical studies
    • Aggarwal, B. B., Kumar, A., Bharti, A. C., Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 2003, 23, 363-398.
    • (2003) Anticancer Res , vol.23 , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 43
    • 84934444244 scopus 로고    scopus 로고
    • Clinical studies with curcumin
    • Hsu, C. H., Cheng, A. L., Clinical studies with curcumin. Adv. Exp. Med. Biol. 2007, 595, 471-480.
    • (2007) Adv. Exp. Med. Biol , vol.595 , pp. 471-480
    • Hsu, C.H.1    Cheng, A.L.2
  • 44
    • 0034772953 scopus 로고    scopus 로고
    • Pharmacodynamic and pharmacokinetic study of oral curcuma extract in patients with colorectal cancer
    • Sharma, R. A., McLelland, H. R., Hill, K. A., Ireson, C. R. et al., Pharmacodynamic and pharmacokinetic study of oral curcuma extract in patients with colorectal cancer. Clin. Cancer Res. 2001, 7, 1894-1900.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1894-1900
    • Sharma, R.A.1    McLelland, H.R.2    Hill, K.A.3    Ireson, C.R.4
  • 45
    • 84892711316 scopus 로고    scopus 로고
    • Comparative absorption of curcumin formulations
    • Jager, R., Lowery, R. P., Calvanese, A. V., Joy, J. M. et al., Comparative absorption of curcumin formulations. Nutr. J. 2014, 13, 11.
    • (2014) Nutr. J. , vol.13 , pp. 11
    • Jager, R.1    Lowery, R.P.2    Calvanese, A.V.3    Joy, J.M.4
  • 47
    • 84855837427 scopus 로고    scopus 로고
    • Curcumin nanoformulations: a future nanomedicine for cancer
    • Yallapu, M. M., Jaggi, M., Chauhan, S. C., Curcumin nanoformulations: a future nanomedicine for cancer. Drug Discov. Today 2012, 17, 71-80.
    • (2012) Drug Discov. Today , vol.17 , pp. 71-80
    • Yallapu, M.M.1    Jaggi, M.2    Chauhan, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.