Genetic basis of common human disease: Insight into the role of missense SNPs from genome-wide association studies

Journal of Molecular Biology

Volumn 427, Issue 13, 2015, Pages 2271-2289

  Pal, Lipika R ^a   Moult, John ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b Bldg 142   (United States)

Author keywords

complex trait disease; GWAS; nonsynonymous; protein structure

Indexed keywords

AMINO ACID; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAM PROTEIN; ADAMTS13 PROTEIN, HUMAN; MACROPHAGE STIMULATING PROTEIN; ONCOPROTEIN; PROTEIN; SCATTER FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BLOOD PRESSURE; CORONARY ARTERY DISEASE; DISEASE PREDISPOSITION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC ASSOCIATION; GENOME; HUMAN; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; CHEMISTRY; CROHN DISEASE; GENETIC PREDISPOSITION; GENETICS; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; PROCEDURES; PROTEIN CONFORMATION; RHEUMATOID ARTHRITIS;

ADAM PROTEINS; ALLELES; ARTHRITIS, RHEUMATOID; CORONARY ARTERY DISEASE; CROHN DISEASE; DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HEPATOCYTE GROWTH FACTOR; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN CONFORMATION; PROTEINS; PROTO-ONCOGENE PROTEINS;

EID: 84930086838     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2015.04.014     Document Type: Article

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