Protein characterization of a candidate mechanism SNP for Crohn's disease: The macrophage stimulating protein R689C substitution

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Gorlatova, Natalia ^a   Chao, Kinlin ^a   Pal, Lipika R ^a   Araj, Rawan Hanna ^a   Galkin, Andrey ^a   Turko, Illarion ^a,b   Moult, John ^a,c   Herzberg, Osnat ^a,c  

^a UNIVERSITY OF MARYLAND   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^c Bldg 142   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYSTEINE; DISULFIDE; MACROPHAGE ACTIVATING FACTOR; MATRIPTASE; MATRIPTASE 1; PROTEIN TYROSINE KINASE; THIOL; UNCLASSIFIED DRUG; VALINE; MACROPHAGE STIMULATING PROTEIN; MUTANT PROTEIN; ONCOPROTEIN; RON PROTEIN; SCATTER FACTOR;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DOWN REGULATION; FLUOROMETRY; GENE; GENE LOCUS; GENETIC CODE; GENETIC RISK; HUMAN; IN VIVO STUDY; MACROPHAGE; MACROPHAGE STIMULATING PROTEIN 1 GENE; MISSENSE MUTATION; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE; THERMOSTABILITY; ULCERATIVE COLITIS; GENETICS; METABOLISM; PROTEIN BINDING; PROTEIN STABILITY;

AMINO ACID SUBSTITUTION; COLITIS, ULCERATIVE; CROHN DISEASE; DOWN-REGULATION; HEPATOCYTE GROWTH FACTOR; HUMANS; MUTANT PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

EID: 80455174463     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027269     Document Type: Article

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