-
1
-
-
0023130088
-
Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: Implications for behavioral recovery from brain injury
-
C.A. Altar, M.R. Marien, and J.F. Marshall Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: implications for behavioral recovery from brain injury J. Neurochem. 48 1987 390 399
-
(1987)
J. Neurochem.
, vol.48
, pp. 390-399
-
-
Altar, C.A.1
Marien, M.R.2
Marshall, J.F.3
-
2
-
-
84864855869
-
Parkinson's disease, insulin resistance and novel agents of neuroprotection
-
I. Aviles-Olmos, P. Limousin, A. Lees, and T. Foltynie Parkinson's disease, insulin resistance and novel agents of neuroprotection Brain 136 2013 374 384
-
(2013)
Brain
, vol.136
, pp. 374-384
-
-
Aviles-Olmos, I.1
Limousin, P.2
Lees, A.3
Foltynie, T.4
-
3
-
-
0026801390
-
Reversal of high-fat diet-induced obesity in female rats
-
T.J. Bartness, D.R. Polk, W.R. McGriff, T.G. Youngstrom, and M. DiGirolamo Reversal of high-fat diet-induced obesity in female rats Am. J. Physiol. 263 1992 R790 R797
-
(1992)
Am. J. Physiol.
, vol.263
, pp. R790-R797
-
-
Bartness, T.J.1
Polk, D.R.2
McGriff, W.R.3
Youngstrom, T.G.4
Digirolamo, M.5
-
4
-
-
79960673874
-
Young and middle-aged rats exhibit isometric forelimb force control deficits in a model of early-stage Parkinson's disease
-
C.S. Bethel-Brown, J.K. Morris, and J.A. Stanford Young and middle-aged rats exhibit isometric forelimb force control deficits in a model of early-stage Parkinson's disease Behav. Brain Res. 225 2011 97 103
-
(2011)
Behav. Brain Res.
, vol.225
, pp. 97-103
-
-
Bethel-Brown, C.S.1
Morris, J.K.2
Stanford, J.A.3
-
5
-
-
34248164439
-
PGC-1alpha Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations: A replicate case-control study
-
A. Bhat, A. Koul, E. Rai, S. Sharma, M.K. Dhar, and R.N. Bamezai PGC-1alpha Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations: a replicate case-control study Hum. Genet. 121 2007 609 614
-
(2007)
Hum. Genet.
, vol.121
, pp. 609-614
-
-
Bhat, A.1
Koul, A.2
Rai, E.3
Sharma, S.4
Dhar, M.K.5
Bamezai, R.N.6
-
6
-
-
77649275112
-
Role of Nrf1 in antioxidant response element-mediated gene expression and beyond
-
M. Biswas, and J.Y. Chan Role of Nrf1 in antioxidant response element-mediated gene expression and beyond Toxicol. Appl. Pharmacol. 244 2010 16 20
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.244
, pp. 16-20
-
-
Biswas, M.1
Chan, J.Y.2
-
7
-
-
64549127790
-
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
C. Canto, and J. Auwerx PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure Curr. Opin. Lipidol. 20 2009 98 105
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
8
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
C. Canto, Z. Gerhart-Hines, J.N. Feige, M. Lagouge, L. Noriega, J.C. Milne, P.J. Elliott, P. Puigserver, and J. Auwerx AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity Nature 458 2009 1056 1060
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
9
-
-
72949122084
-
AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
J.S. Choi, C. Park, and J.W. Jeong AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Biochem. Biophys. Res. Commun. 391 2010 147 151
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.391
, pp. 147-151
-
-
Choi, J.S.1
Park, C.2
Jeong, J.W.3
-
10
-
-
13844275515
-
Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity
-
J.Y. Choi, E.H. Jang, C.S. Park, and J.H. Kang Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity Free Radical Biol. Med. 38 2005 806 816
-
(2005)
Free Radical Biol. Med.
, vol.38
, pp. 806-816
-
-
Choi, J.Y.1
Jang, E.H.2
Park, C.S.3
Kang, J.H.4
-
11
-
-
28844493414
-
Physiological and pathological changes in glucose regulate brain Akt and glycogen synthase kinase-3
-
B. Clodfelder-Miller, P. De Sarno, A.A. Zmijewska, L. Song, and R.S. Jope Physiological and pathological changes in glucose regulate brain Akt and glycogen synthase kinase-3 J. Biol. Chem. 280 2005 39723 39731
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39723-39731
-
-
Clodfelder-Miller, B.1
De Sarno, P.2
Zmijewska, A.A.3
Song, L.4
Jope, R.S.5
-
12
-
-
78751490442
-
Beta-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency
-
S. Costes, C.J. Huang, T. Gurlo, M. Daval, A.V. Matveyenko, R.A. Rizza, A.E. Butler, and P.C. Butler beta-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency Diabetes 60 2011 227 238
-
(2011)
Diabetes
, vol.60
, pp. 227-238
-
-
Costes, S.1
Huang, C.J.2
Gurlo, T.3
Daval, M.4
Matveyenko, A.V.5
Rizza, R.A.6
Butler, A.E.7
Butler, P.C.8
-
13
-
-
84905482172
-
The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy
-
S. Geisler, S. Vollmer, S. Golombek, and P.J. Kahle The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy J. Cell Sci. 127 2014 3280 3293
-
(2014)
J. Cell Sci.
, vol.127
, pp. 3280-3293
-
-
Geisler, S.1
Vollmer, S.2
Golombek, S.3
Kahle, P.J.4
-
14
-
-
66149153033
-
Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
-
A.A. Gupte, G.L. Bomhoff, J.K. Morris, B.K. Gorres, and P.C. Geiger Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats J. Appl. Physiol. 106 2009 1425 1434
-
(2009)
J. Appl. Physiol.
, vol.106
, pp. 1425-1434
-
-
Gupte, A.A.1
Bomhoff, G.L.2
Morris, J.K.3
Gorres, B.K.4
Geiger, P.C.5
-
15
-
-
78650535334
-
High-fat diet-induced obesity in animal models
-
N. Hariri, and L. Thibault High-fat diet-induced obesity in animal models Nutr. Res. Rev. 23 2010 270 299
-
(2010)
Nutr. Res. Rev.
, vol.23
, pp. 270-299
-
-
Hariri, N.1
Thibault, L.2
-
16
-
-
34147190028
-
Type 2 diabetes and the risk of Parkinson's disease
-
G. Hu, P. Jousilahti, S. Bidel, R. Antikainen, and J. Tuomilehto Type 2 diabetes and the risk of Parkinson's disease Diabetes Care 30 2007 842 847
-
(2007)
Diabetes Care
, vol.30
, pp. 842-847
-
-
Hu, G.1
Jousilahti, P.2
Bidel, S.3
Antikainen, R.4
Tuomilehto, J.5
-
17
-
-
79954518275
-
TCF11 at the crossroads of oxidative stress and the ubiquitin proteasome system
-
A. Koch, J. Steffen, and E. Kruger TCF11 at the crossroads of oxidative stress and the ubiquitin proteasome system Cell Cycle 10 2011 1200 1207
-
(2011)
Cell Cycle
, vol.10
, pp. 1200-1207
-
-
Koch, A.1
Steffen, J.2
Kruger, E.3
-
18
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
-
S.H. Koo, H. Satoh, S. Herzig, C.H. Lee, S. Hedrick, R. Kulkarni, R.M. Evans, J. Olefsky, and M. Montminy PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3 Nat. Med. 10 2004 530 534
-
(2004)
Nat. Med.
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
Lee, C.H.4
Hedrick, S.5
Kulkarni, R.6
Evans, R.M.7
Olefsky, J.8
Montminy, M.9
-
19
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
M.A. Lawlor, and D.R. Alessi PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cell Sci. 114 2001 2903 2910
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
20
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
-
D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
22
-
-
54549097933
-
Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease
-
J.K. Morris, H. Zhang, A.A. Gupte, G.L. Bomhoff, J.A. Stanford, and P.C. Geiger Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease Brain Res. 1240 2008 185 195
-
(2008)
Brain Res.
, vol.1240
, pp. 185-195
-
-
Morris, J.K.1
Zhang, H.2
Gupte, A.A.3
Bomhoff, G.L.4
Stanford, J.A.5
Geiger, P.C.6
-
23
-
-
0035951489
-
TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter
-
M.C. Myhrstad, C. Husberg, P. Murphy, O. Nordstrom, R. Blomhoff, J.O. Moskaug, and A.B. Kolsto TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter Biochim. Biophys. Acta 1517 2001 212 219
-
(2001)
Biochim. Biophys. Acta
, vol.1517
, pp. 212-219
-
-
Myhrstad, M.C.1
Husberg, C.2
Murphy, P.3
Nordstrom, O.4
Blomhoff, R.5
Moskaug, J.O.6
Kolsto, A.B.7
-
24
-
-
84881291056
-
Exposure to high fat during early development impairs adaptations in dopamine and neuroendocrine responses to repeated stress
-
L. Naef, A. Gratton, and C.D. Walker Exposure to high fat during early development impairs adaptations in dopamine and neuroendocrine responses to repeated stress Stress 16 2013 540 548
-
(2013)
Stress
, vol.16
, pp. 540-548
-
-
Naef, L.1
Gratton, A.2
Walker, C.D.3
-
26
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
P. Puigserver, J. Rhee, J. Donovan, C.J. Walkey, J.C. Yoon, F. Oriente, Y. Kitamura, J. Altomonte, H. Dong, D. Accili, and B.M. Spiegelman Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction Nature 423 2003 550 555
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
27
-
-
79960566233
-
AMP-activated protein kinase: A potential player in Alzheimer's disease
-
A. Salminen, K. Kaarniranta, A. Haapasalo, H. Soininen, and M. Hiltunen AMP-activated protein kinase: a potential player in Alzheimer's disease J. Neurochem. 118 2011 460 474
-
(2011)
J. Neurochem.
, vol.118
, pp. 460-474
-
-
Salminen, A.1
Kaarniranta, K.2
Haapasalo, A.3
Soininen, H.4
Hiltunen, M.5
-
28
-
-
84875235515
-
Shared dysregulated pathways lead to Parkinson's disease and diabetes
-
J.A. Santiago, and J.A. Potashkin Shared dysregulated pathways lead to Parkinson's disease and diabetes Trends Mol. Med. 19 2013 176 186
-
(2013)
Trends Mol. Med.
, vol.19
, pp. 176-186
-
-
Santiago, J.A.1
Potashkin, J.A.2
-
29
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
J. St-Pierre, S. Drori, M. Uldry, J.M. Silvaggi, J. Rhee, S. Jager, C. Handschin, K. Zheng, J. Lin, W. Yang, D.K. Simon, R. Bachoo, and B.M. Spiegelman Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators Cell 127 2006 397 408
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
30
-
-
77957341511
-
Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop
-
J. Steffen, M. Seeger, A. Koch, and E. Kruger Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop Mol. Cell 40 2010 147 158
-
(2010)
Mol. Cell
, vol.40
, pp. 147-158
-
-
Steffen, J.1
Seeger, M.2
Koch, A.3
Kruger, E.4
-
31
-
-
84897523233
-
A calcium-deficient diet in rat dams during gestation and nursing affects hepatic 11beta-hydroxysteroid dehydrogenase-1 expression in the offspring
-
J. Takaya, S. Yamanouchi, and K. Kaneko A calcium-deficient diet in rat dams during gestation and nursing affects hepatic 11beta-hydroxysteroid dehydrogenase-1 expression in the offspring PLoS One 9 2014 e84125
-
(2014)
PLoS One
, vol.9
, pp. e84125
-
-
Takaya, J.1
Yamanouchi, S.2
Kaneko, K.3
-
32
-
-
84855459760
-
Obesity is associated with hypothalamic injury in rodents and humans
-
J.P. Thaler, C.X. Yi, E.A. Schur, S.J. Guyenet, B.H. Hwang, M.O. Dietrich, X. Zhao, D.A. Sarruf, V. Izgur, K.R. Maravilla, H.T. Nguyen, J.D. Fischer, M.E. Matsen, B.E. Wisse, G.J. Morton, T.L. Horvath, D.G. Baskin, M.H. Tschop, and M.W. Schwartz Obesity is associated with hypothalamic injury in rodents and humans J. Clin. Invest. 122 2012 153 162
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 153-162
-
-
Thaler, J.P.1
Yi, C.X.2
Schur, E.A.3
Guyenet, S.J.4
Hwang, B.H.5
Dietrich, M.O.6
Zhao, X.7
Sarruf, D.A.8
Izgur, V.9
Maravilla, K.R.10
Nguyen, H.T.11
Fischer, J.D.12
Matsen, M.E.13
Wisse, B.E.14
Morton, G.J.15
Horvath, T.L.16
Baskin, D.G.17
Tschop, M.H.18
Schwartz, M.W.19
-
33
-
-
0014954436
-
Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system
-
U. Ungerstedt, and G.W. Arbuthnott Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system Brain Res. 24 1970 485 493
-
(1970)
Brain Res.
, vol.24
, pp. 485-493
-
-
Ungerstedt, U.1
Arbuthnott, G.W.2
-
34
-
-
33744494576
-
Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex
-
A. Wu, Z. Ying, and F. Gomez-Pinilla Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex Eur. J. Neurosci. 23 2006 2573 2580
-
(2006)
Eur. J. Neurosci.
, vol.23
, pp. 2573-2580
-
-
Wu, A.1
Ying, Z.2
Gomez-Pinilla, F.3
-
35
-
-
84859757164
-
Brain insulin resistance accelerates Abeta fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes
-
N. Yamamoto, T. Matsubara, K. Sobue, M. Tanida, R. Kasahara, K. Naruse, H. Taniura, T. Sato, and K. Suzuki Brain insulin resistance accelerates Abeta fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes J. Neurochem. 121 2012 619 628
-
(2012)
J. Neurochem.
, vol.121
, pp. 619-628
-
-
Yamamoto, N.1
Matsubara, T.2
Sobue, K.3
Tanida, M.4
Kasahara, R.5
Naruse, K.6
Taniura, H.7
Sato, T.8
Suzuki, K.9
-
36
-
-
84872431424
-
Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes
-
Y. Yang, D. Ma, Y. Wang, T. Jiang, S. Hu, M. Zhang, X. Yu, and C.X. Gong Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes J. Alzheimers Dis. 33 2013 329 338
-
(2013)
J. Alzheimers Dis.
, vol.33
, pp. 329-338
-
-
Yang, Y.1
Ma, D.2
Wang, Y.3
Jiang, T.4
Hu, S.5
Zhang, M.6
Yu, X.7
Gong, C.X.8
-
37
-
-
84867607875
-
Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: Possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain
-
Q. Zhao, Y. Niu, K. Matsumoto, K. Tsuneyama, K. Tanaka, T. Miyata, and T. Yokozawa Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain BMC Complement. Altern. Med. 12 2012 188
-
(2012)
BMC Complement. Altern. Med.
, vol.12
, pp. 188
-
-
Zhao, Q.1
Niu, Y.2
Matsumoto, K.3
Tsuneyama, K.4
Tanaka, K.5
Miyata, T.6
Yokozawa, T.7
-
38
-
-
77958072667
-
PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease
-
52ra73
-
B. Zheng, Z. Liao, J.J. Locascio, K.A. Lesniak, S.S. Roderick, M.L. Watt, A.C. Eklund, Y. Zhang-James, P.D. Kim, M.A. Hauser, E. Grunblatt, L.B. Moran, S.A. Mandel, P. Riederer, R.M. Miller, H.J. Federoff, U. Wullner, S. Papapetropoulos, M.B. Youdim, I. Cantuti-Castelvetri, A.B. Young, J.M. Vance, R.L. Davis, J.C. Hedreen, C.H. Adler, T.G. Beach, M.B. Graeber, F.A. Middleton, J.C. Rochet, C.R. Scherzer, and P.D.G.E.C. Global PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease 52ra73 Sci. Transl. Med. 2 2010
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
Lesniak, K.A.4
Roderick, S.S.5
Watt, M.L.6
Eklund, A.C.7
Zhang-James, Y.8
Kim, P.D.9
Hauser, M.A.10
Grunblatt, E.11
Moran, L.B.12
Mandel, S.A.13
Riederer, P.14
Miller, R.M.15
Federoff, H.J.16
Wullner, U.17
Papapetropoulos, S.18
Youdim, M.B.19
Cantuti-Castelvetri, I.20
Young, A.B.21
Vance, J.M.22
Davis, R.L.23
Hedreen, J.C.24
Adler, C.H.25
Beach, T.G.26
Graeber, M.B.27
Middleton, F.A.28
Rochet, J.C.29
Scherzer, C.R.30
Global, P.D.G.E.C.31
more..
-
39
-
-
37549063624
-
Anesthesia's effects on plasma glucose and insulin and cardiac hexokinase at similar hemodynamics and without major surgical stress in fed rats
-
table of contents
-
C.J. Zuurbier, P.J. Keijzers, A. Koeman, H.B. Van Wezel, and M.W. Hollmann Anesthesia's effects on plasma glucose and insulin and cardiac hexokinase at similar hemodynamics and without major surgical stress in fed rats Anesth. Analg. 106 2008 135 142 table of contents
-
(2008)
Anesth. Analg.
, vol.106
, pp. 135-142
-
-
Zuurbier, C.J.1
Keijzers, P.J.2
Koeman, A.3
Van Wezel, H.B.4
Hollmann, M.W.5
|