-
2
-
-
36949083936
-
Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
-
Mitchell, P. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 191, 144-148 (1961).
-
(1961)
Nature
, vol.191
, pp. 144-148
-
-
Mitchell, P.1
-
3
-
-
0028114231
-
Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria
-
Abrahams, J. P., Leslie, A. G., Lutter, R. & Walker, J. E. Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria. Nature 370, 621-628 (1994).
-
(1994)
Nature
, vol.370
, pp. 621-628
-
-
Abrahams, J.P.1
Leslie, A.G.2
Lutter, R.3
Walker, J.E.4
-
4
-
-
78049288139
-
Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria
-
Watt, I. N., Montgomery, M. G., Runswick, M. J., Leslie, A. G. & Walker, J. E. Bioenergetic cost of making an adenosine triphosphate molecule in animal mitochondria. Proc. Natl Acad. Sci. USA 107, 16823-16827 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 16823-16827
-
-
Watt, I.N.1
Montgomery, M.G.2
Runswick, M.J.3
Leslie, A.G.4
Walker, J.E.5
-
5
-
-
0028890031
-
Structure at 2.8 a resolution of cytochrome c oxidase from Paracoccus denitrificans
-
Iwata, S., Ostermeier, C., Ludwig, B. & Michel, H. Structure at 2.8 A resolution of cytochrome c oxidase from Paracoccus denitrificans. Nature 376, 660-669 (1995).
-
(1995)
Nature
, vol.376
, pp. 660-669
-
-
Iwata, S.1
Ostermeier, C.2
Ludwig, B.3
Michel, H.4
-
6
-
-
0029942862
-
The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A
-
Tsukihara, T. et al. The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Science 272, 1136-1144 (1996).
-
(1996)
Science
, vol.272
, pp. 1136-1144
-
-
Tsukihara, T.1
-
7
-
-
0032479524
-
Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex
-
Iwata, S. et al. Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex. Science 281, 64-71 (1998).
-
(1998)
Science
, vol.281
, pp. 64-71
-
-
Iwata, S.1
-
8
-
-
21244503033
-
Crystal structure of mitochondrial respiratory membrane protein complex II
-
Sun, F. et al. Crystal structure of mitochondrial respiratory membrane protein complex II. Cell 121, 1043-1057 (2005).
-
(2005)
Cell
, vol.121
, pp. 1043-1057
-
-
Sun, F.1
-
9
-
-
84874352529
-
Crystal structure of the entire respiratory complex i
-
Baradaran, R., Berrisford, J. M., Minhas, G. S. & Sazanov, L. A. Crystal structure of the entire respiratory complex I. Nature 494, 443-448 (2013).
-
(2013)
Nature
, vol.494
, pp. 443-448
-
-
Baradaran, R.1
Berrisford, J.M.2
Minhas, G.S.3
Sazanov, L.A.4
-
10
-
-
84864689276
-
A review of the binding-change mechanism for proton-Translocating transhydrogenase
-
Jackson, J. B. A review of the binding-change mechanism for proton-Translocating transhydrogenase. Biochim. Biophys. Acta 1817, 1839-1846 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1817
, pp. 1839-1846
-
-
Jackson, J.B.1
-
11
-
-
0036784018
-
Reverse flux through cardiac NADP+-isocitrate dehydrogenase under normoxia and ischemia
-
Comte, B., Vincent, G., Bouchard, B., Benderdour, M. & Des Rosiers, C. Reverse flux through cardiac NADP+-isocitrate dehydrogenase under normoxia and ischemia. Am. J. Physiol. Heart Circ. Physiol. 283, H1505-H1514 (2002).
-
(2002)
Am. J. Physiol. Heart Circ. Physiol.
, vol.283
, pp. H1505-H1514
-
-
Comte, B.1
Vincent, G.2
Bouchard, B.3
Benderdour, M.4
Des Rosiers, C.5
-
12
-
-
0028339522
-
Proton-Translocating transhydrogenase and NAD-And NADP-linked isocitrate dehydrogenases operate in a substrate cycle which contributes to fine regulation of the tricarboxylic acid cycle activity in mitochondria
-
Sazanov, L. A. & Jackson, J. B. Proton-Translocating transhydrogenase and NAD-And NADP-linked isocitrate dehydrogenases operate in a substrate cycle which contributes to fine regulation of the tricarboxylic acid cycle activity in mitochondria. FEBS Lett. 344, 109-116 (1994).
-
(1994)
FEBS Lett.
, vol.344
, pp. 109-116
-
-
Sazanov, L.A.1
Jackson, J.B.2
-
13
-
-
0028269382
-
Catalytic sector of complex i (NADH:ubiquinone oxidoreductase): Subunit stoichiometry and substrate-induced conformation changes
-
Belogrudov, G. & Hatefi, Y. Catalytic sector of complex I (NADH:ubiquinone oxidoreductase): subunit stoichiometry and substrate-induced conformation changes. Biochemistry 33, 4571-4576 (1994).
-
(1994)
Biochemistry
, vol.33
, pp. 4571-4576
-
-
Belogrudov, G.1
Hatefi, Y.2
-
14
-
-
2542421934
-
Substrate-induced conformational change in bacterial complex i
-
Mamedova, A. A., Holt, P. J., Carroll, J. & Sazanov, L. A. Substrate-induced conformational change in bacterial complex I. J. Biol. Chem. 279, 23830-23836 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23830-23836
-
-
Mamedova, A.A.1
Holt, P.J.2
Carroll, J.3
Sazanov, L.A.4
-
15
-
-
52949114593
-
Chemical and NADH-induced ROS-dependent cross-linking between subunits of complex i from Escherichia coli and
-
Berrisford, J. M., Thompson, C. J. & Sazanov, L. A. Chemical and NADH-induced, ROS-dependent, cross-linking between subunits of complex I from Escherichia coli and Thermus thermophilus. Biochemistry 47, 10262-10270 (2008).
-
(2008)
Thermus Thermophilus. Biochemistry
, vol.47
, pp. 10262-10270
-
-
Berrisford, J.M.1
Thompson, C.J.2
Sazanov, L.A.3
-
16
-
-
34547096741
-
Single particle analysis confirms distal location of subunits NuoL and NuoM in Escherichia coli complex i
-
Baranova, E. A., Morgan, D. J. & Sazanov, L. A. Single particle analysis confirms distal location of subunits NuoL and NuoM in Escherichia coli complex I. J. Struct. Biol. 159, 238-242 (2007).
-
(2007)
J. Struct. Biol.
, vol.159
, pp. 238-242
-
-
Baranova, E.A.1
Morgan, D.J.2
Sazanov, L.A.3
-
17
-
-
0242322000
-
The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli complex I: Implications for the mechanism of proton pumping
-
Holt, P. J., Morgan, D. J. & Sazanov, L. A. The location of NuoL and NuoM subunits in the membrane domain of the Escherichia coli complex I: implications for the mechanism of proton pumping. J. Biol. Chem. 278, 43114-43120 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43114-43120
-
-
Holt, P.J.1
Morgan, D.J.2
Sazanov, L.A.3
-
18
-
-
0034691280
-
Resolution of the membrane domain of bovine complex i into subcomplexes: Implications for the structural organization of the enzyme
-
Sazanov, L. A., Peak-Chew, S. Y., Fearnley, I. M. & Walker, J. E. Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme. Biochemistry 39, 7229-7235 (2000).
-
(2000)
Biochemistry
, vol.39
, pp. 7229-7235
-
-
Sazanov, L.A.1
Peak-Chew, S.Y.2
Fearnley, I.M.3
Walker, J.E.4
-
19
-
-
0034665878
-
Cryo-electron crystallography of two sub-complexes of bovine complex i reveals the relationship between the membrane and peripheral arms
-
Sazanov, L. A. & Walker, J. E. Cryo-electron crystallography of two sub-complexes of bovine complex I reveals the relationship between the membrane and peripheral arms. J. Mol. Biol. 302, 455-464 (2000).
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 455-464
-
-
Sazanov, L.A.1
Walker, J.E.2
-
20
-
-
46349107838
-
Three-dimensional structure of respiratory complex i from Escherichia coli in ice in the presence of nucleotides
-
Morgan, D. J. & Sazanov, L. A. Three-dimensional structure of respiratory complex I from Escherichia coli in ice in the presence of nucleotides. Biochim. Biophys. Acta 1777, 711-718 (2008).
-
(2008)
Biochim. Biophys. Acta
, vol.1777
, pp. 711-718
-
-
Morgan, D.J.1
Sazanov, L.A.2
-
21
-
-
0032540273
-
Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice
-
Grigorieff, N. Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice. J. Mol. Biol. 277, 1033-1046 (1998).
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 1033-1046
-
-
Grigorieff, N.1
-
22
-
-
0032512616
-
Consistent structure between bacterial and mitochondrial NADH:ubiquinone oxidoreductase (complex I)
-
Guenebaut, V., Schlitt, A., Weiss, H., Leonard, K. & Friedrich, T. Consistent structure between bacterial and mitochondrial NADH:ubiquinone oxidoreductase (complex I). J. Mol. Biol. 276, 105-112 (1998).
-
(1998)
J. Mol. Biol.
, vol.276
, pp. 105-112
-
-
Guenebaut, V.1
Schlitt, A.2
Weiss, H.3
Leonard, K.4
Friedrich, T.5
-
23
-
-
79953131437
-
Evolution of respiratory complex I: Supernumerary subunits are present in the alpha-proteobacterial enzyme
-
Yip, C. Y., Harbour, M. E., Jayawardena, K., Fearnley, I. M. & Sazanov, L. A. Evolution of respiratory complex I: 'supernumerary' subunits are present in the alpha-proteobacterial enzyme. J. Biol. Chem. 286, 5023-5033 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5023-5033
-
-
Yip, C.Y.1
Harbour, M.E.2
Jayawardena, K.3
Fearnley, I.M.4
Sazanov, L.A.5
-
24
-
-
33746329868
-
Energy converting NADH:quinone oxidoreductase (complex I)
-
Brandt, U. Energy converting NADH:quinone oxidoreductase (complex I). Annu. Rev. Biochem. 75, 69-92 (2006).
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 69-92
-
-
Brandt, U.1
-
25
-
-
0027104114
-
The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains
-
Walker, J. E. The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains. Q. Rev. Biophys. 25, 253-324 (1992).
-
(1992)
Q. Rev. Biophys.
, vol.25
, pp. 253-324
-
-
Walker, J.E.1
-
26
-
-
0038771142
-
The nuclear encoded subunits of complex i from bovine heart mitochondria
-
Hirst, J., Carroll, J., Fearnley, I. M., Shannon, R. J. & Walker, J. E. The nuclear encoded subunits of complex I from bovine heart mitochondria. Biochim. Biophys. Acta 1604, 135-150 (2003).
-
(2003)
Biochim. Biophys. Acta
, vol.1604
, pp. 135-150
-
-
Hirst, J.1
Carroll, J.2
Fearnley, I.M.3
Shannon, R.J.4
Walker, J.E.5
-
27
-
-
84915761829
-
Architecture of mammalian respiratory complex i
-
Vinothkumar, K. R., Zhu, J. & Hirst, J. Architecture of mammalian respiratory complex I. Nature 515, 80-84 (2014).
-
(2014)
Nature
, vol.515
, pp. 80-84
-
-
Vinothkumar, K.R.1
Zhu, J.2
Hirst, J.3
-
28
-
-
77953136730
-
Small single transmembrane domain (STMD) proteins organize the hydrophobic subunits of large membrane protein complexes
-
Zickermann, V., Angerer, H., Ding, M. G., Nubel, E. & Brandt, U. Small single transmembrane domain (STMD) proteins organize the hydrophobic subunits of large membrane protein complexes. FEBS Lett. 584, 2516-2525 (2010).
-
(2010)
FEBS Lett.
, vol.584
, pp. 2516-2525
-
-
Zickermann, V.1
Angerer, H.2
Ding, M.G.3
Nubel, E.4
Brandt, U.5
-
29
-
-
77954848120
-
Functional modules and structural basis of conformational coupling in mitochondrial complex i
-
Hunte, C., Zickermann, V. & Brandt, U. Functional modules and structural basis of conformational coupling in mitochondrial complex I. Science 329, 448-451 (2010).
-
(2010)
Science
, vol.329
, pp. 448-451
-
-
Hunte, C.1
Zickermann, V.2
Brandt, U.3
-
30
-
-
80052097536
-
Respiratory complex I: 'steam engine' of the cell?
-
Efremov, R. G. & Sazanov, L. A. Respiratory complex I: 'steam engine' of the cell? Curr. Opin. Struct. Biol. 21, 532-540 (2011).
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 532-540
-
-
Efremov, R.G.1
Sazanov, L.A.2
-
31
-
-
0026484793
-
Conservation of sequences of subunits of mitochondrial complex i and their relationships with other proteins
-
Fearnley, I. M. & Walker, J. E. Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins. Biochim. Biophys. Acta 1140, 105-134 (1992).
-
(1992)
Biochim. Biophys. Acta
, vol.1140
, pp. 105-134
-
-
Fearnley, I.M.1
Walker, J.E.2
-
32
-
-
84922479528
-
Mechanistic insight from the crystal structure of mitochondrial complex i
-
Zickermann, V. et al. Mechanistic insight from the crystal structure of mitochondrial complex I. Science 347, 44-49 (2015).
-
(2015)
Science
, vol.347
, pp. 44-49
-
-
Zickermann, V.1
-
33
-
-
70350351403
-
Structural basis for the mechanism of respiratory complex i
-
Berrisford, J. M. & Sazanov, L. A. Structural basis for the mechanism of respiratory complex I. J. Biol. Chem. 284, 29773-29783 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 29773-29783
-
-
Berrisford, J.M.1
Sazanov, L.A.2
-
34
-
-
33644872938
-
Structure of the hydrophilic domain of respiratory complex i from
-
Sazanov, L. A. & Hinchliffe, P. Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus. Science 311, 1430-1436 (2006).
-
(2006)
Thermus Thermophilus. Science
, vol.311
, pp. 1430-1436
-
-
Sazanov, L.A.1
Hinchliffe, P.2
-
35
-
-
80052068980
-
Structure of the membrane domain of respiratory complex i
-
Efremov, R. G. & Sazanov, L. A. Structure of the membrane domain of respiratory complex I. Nature 476, 414-420 (2011).
-
(2011)
Nature
, vol.476
, pp. 414-420
-
-
Efremov, R.G.1
Sazanov, L.A.2
-
36
-
-
77952979824
-
The architecture of respiratory complex i
-
Efremov, R. G., Baradaran, R. & Sazanov, L. A. The architecture of respiratory complex I. Nature 465, 441-445 (2010).
-
(2010)
Nature
, vol.465
, pp. 441-445
-
-
Efremov, R.G.1
Baradaran, R.2
Sazanov, L.A.3
-
37
-
-
33847687662
-
Respiratory complex I: Mechanistic and structural insights provided by the crystal structure of the hydrophilic domain
-
Sazanov, L. A. Respiratory complex I: mechanistic and structural insights provided by the crystal structure of the hydrophilic domain. Biochemistry 46, 2275-2288 (2007).
-
(2007)
Biochemistry
, vol.46
, pp. 2275-2288
-
-
Sazanov, L.A.1
-
38
-
-
0032490089
-
Iron-sulfur clusters/semiquinones in complex i
-
Ohnishi, T. Iron-sulfur clusters/semiquinones in complex I. Biochim. Biophys. Acta 1364, 186-206 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 186-206
-
-
Ohnishi, T.1
-
39
-
-
0033523919
-
Natural engineering principles of electron tunnelling in biological oxidation-reduction
-
Page, C. C., Moser, C. C., Chen, X. & Dutton, P. L. Natural engineering principles of electron tunnelling in biological oxidation-reduction. Nature 402, 47-52 (1999).
-
(1999)
Nature
, vol.402
, pp. 47-52
-
-
Page, C.C.1
Moser, C.C.2
Chen, X.3
Dutton, P.L.4
-
40
-
-
34249895284
-
Iron-sulfur cluster N7 of the NADH:ubiquinone oxidoreductase (complex I) is essential for stability but not involved in electron transfer
-
Pohl, T. et al. Iron-sulfur cluster N7 of the NADH:ubiquinone oxidoreductase (complex I) is essential for stability but not involved in electron transfer. Biochemistry 46, 6588-6596 (2007).
-
(2007)
Biochemistry
, vol.46
, pp. 6588-6596
-
-
Pohl, T.1
-
41
-
-
0037010862
-
Transmembrane topology of the NuoL, M and N subunits of NADH:quinone oxidoreductase and their homologues among membrane-bound hydrogenases and bona fide antiporters
-
Mathiesen, C. & Hagerhall, C. Transmembrane topology of the NuoL, M and N subunits of NADH:quinone oxidoreductase and their homologues among membrane-bound hydrogenases and bona fide antiporters. Biochim. Biophys. Acta 1556, 121-132 (2002).
-
(2002)
Biochim. Biophys. Acta
, vol.1556
, pp. 121-132
-
-
Mathiesen, C.1
Hagerhall, C.2
-
43
-
-
34447637751
-
Discontinuous membrane helices in transport proteins and their correlation with function
-
Screpanti, E. & Hunte, C. Discontinuous membrane helices in transport proteins and their correlation with function. J. Struct. Biol. 159, 261-267 (2007).
-
(2007)
J. Struct. Biol.
, vol.159
, pp. 261-267
-
-
Screpanti, E.1
Hunte, C.2
-
44
-
-
78349305451
-
Evolutionary origin of a secondary structure: P-helices as cryptic but widespread insertional variations of a-helices that enhance protein functionality
-
Cooley, R. B., Arp, D. J. & Karplus, P. A. Evolutionary origin of a secondary structure: p-helices as cryptic but widespread insertional variations of a-helices that enhance protein functionality. J. Mol. Biol. 404, 232-246 (2010).
-
(2010)
J. Mol. Biol.
, vol.404
, pp. 232-246
-
-
Cooley, R.B.1
Arp, D.J.2
Karplus, P.A.3
-
45
-
-
84864659415
-
The coupling mechanism of respiratory complex i-A structural and evolutionary perspective
-
Efremov, R. G. & Sazanov, L. A. The coupling mechanism of respiratory complex I-A structural and evolutionary perspective. Biochim. Biophys. Acta 1817, 1785-1795 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1817
, pp. 1785-1795
-
-
Efremov, R.G.1
Sazanov, L.A.2
-
46
-
-
0032490104
-
Catalytic properties of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) and the pseudo-reversible active/inactive enzyme transition
-
Vinogradov, A. D. Catalytic properties of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) and the pseudo-reversible active/inactive enzyme transition. Biochim. Biophys. Acta 1364, 169-185 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 169-185
-
-
Vinogradov, A.D.1
-
47
-
-
33749184515
-
Electron tunneling chains of mitochondria
-
Moser, C. C., Farid, T. A., Chobot, S. E. & Dutton, P. L. Electron tunneling chains of mitochondria. Biochim. Biophys. Acta 1757, 1096-1109 (2006).
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 1096-1109
-
-
Moser, C.C.1
Farid, T.A.2
Chobot, S.E.3
Dutton, P.L.4
-
48
-
-
41649119007
-
Real-Time electron transfer in respiratory complex i
-
Verkhovskaya, M. L., Belevich, N., Euro, L., Wikstrom, M. & Verkhovsky, M. I. Real-Time electron transfer in respiratory complex I. Proc. Natl Acad. Sci. USA 105, 3763-3767 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3763-3767
-
-
Verkhovskaya, M.L.1
Belevich, N.2
Euro, L.3
Wikstrom, M.4
Verkhovsky, M.I.5
-
49
-
-
0025349462
-
Coupling site i and the rotenone-sensitive ubisemiquinone in tightly coupled submitochondrial particles
-
Kotlyar, A. B., Sled, V. D., Burbaev, D. S., Moroz, I. A. & Vinogradov, A. D. Coupling site I and the rotenone-sensitive ubisemiquinone in tightly coupled submitochondrial particles. FEBS Lett. 264, 17-20 (1990).
-
(1990)
FEBS Lett.
, vol.264
, pp. 17-20
-
-
Kotlyar, A.B.1
Sled, V.D.2
Burbaev, D.S.3
Moroz, I.A.4
Vinogradov, A.D.5
-
50
-
-
84856917379
-
Mossbauer spectroscopy on respiratory complex I: The iron-sulfur cluster ensemble in the NADH-reduced enzyme is partially oxidized
-
Bridges, H. R., Bill, E. & Hirst, J. Mossbauer spectroscopy on respiratory complex I: the iron-sulfur cluster ensemble in the NADH-reduced enzyme is partially oxidized. Biochemistry 51, 149-158 (2012).
-
(2012)
Biochemistry
, vol.51
, pp. 149-158
-
-
Bridges, H.R.1
Bill, E.2
Hirst, J.3
-
51
-
-
76649102458
-
Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex i by double electron-electron resonance
-
Roessler, M. M. et al. Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron-electron resonance. Proc. Natl Acad. Sci. USA 107, 1930-1935 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 1930-1935
-
-
Roessler, M.M.1
-
52
-
-
33750432874
-
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5?-phosphosulfate reductase
-
Chartron, J. et al. Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5?-phosphosulfate reductase. J. Mol. Biol. 364, 152-169 (2006).
-
(2006)
J. Mol. Biol.
, vol.364
, pp. 152-169
-
-
Chartron, J.1
-
53
-
-
62149134085
-
Protons and how they are transported by proton pumps
-
Buch-Pedersen, M. J., Pedersen, B. P., Veierskov, B., Nissen, P. & Palmgren, M. G. Protons and how they are transported by proton pumps. Pflugers Arch. 457, 573-579 (2009).
-
(2009)
Pflugers Arch.
, vol.457
, pp. 573-579
-
-
Buch-Pedersen, M.J.1
Pedersen, B.P.2
Veierskov, B.3
Nissen, P.4
Palmgren, M.G.5
-
54
-
-
69249116947
-
Structure and mechanism of a Na+-independent amino acid transporter
-
Shaffer, P. L., Goehring, A., Shankaranarayanan, A. & Gouaux, E. Structure and mechanism of a Na+-independent amino acid transporter. Science 325, 1010-1014 (2009).
-
(2009)
Science
, vol.325
, pp. 1010-1014
-
-
Shaffer, P.L.1
Goehring, A.2
Shankaranarayanan, A.3
Gouaux, E.4
-
55
-
-
77957257818
-
Single site mutations in the hetero-oligomeric Mrp antiporter from alkaliphilic Bacillus pseudofirmus OF4 that affect Na+/H+ antiport activity, sodium exclusion, individual Mrp protein levels, or Mrp complex formation
-
Morino, M. et al. Single site mutations in the hetero-oligomeric Mrp antiporter from alkaliphilic Bacillus pseudofirmus OF4 that affect Na+/H+ antiport activity, sodium exclusion, individual Mrp protein levels, or Mrp complex formation. J. Biol. Chem. 285, 30942-30950 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 30942-30950
-
-
Morino, M.1
-
56
-
-
84885576596
-
A two-domain elevator mechanism for sodium/proton antiport
-
Lee, C. et al. A two-domain elevator mechanism for sodium/proton antiport. Nature 501, 573-577 (2013).
-
(2013)
Nature
, vol.501
, pp. 573-577
-
-
Lee, C.1
-
57
-
-
21744436321
-
Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH
-
Hunte, C. et al. Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH. Nature 435, 1197-1202 (2005).
-
(2005)
Nature
, vol.435
, pp. 1197-1202
-
-
Hunte, C.1
-
58
-
-
66249098083
-
Unlocking the molecular secrets of sodium-coupled transporters
-
Krishnamurthy, H., Piscitelli, C. L. & Gouaux, E. Unlocking the molecular secrets of sodium-coupled transporters. Nature 459, 347-355 (2009).
-
(2009)
Nature
, vol.459
, pp. 347-355
-
-
Krishnamurthy, H.1
Piscitelli, C.L.2
Gouaux, E.3
-
59
-
-
84886421872
-
Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT
-
Kalayil, S., Schulze, S. & Kuhlbrandt, W. Arginine oscillation explains Na+ independence in the substrate/product antiporter CaiT. Proc. Natl Acad. Sci. USA 110, 17296-17301 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 17296-17301
-
-
Kalayil, S.1
Schulze, S.2
Kuhlbrandt, W.3
-
60
-
-
84867275957
-
The deactive form of respiratory complex i from mammalian mitochondria is a Na+/H+ antiporter
-
Roberts, P. G. & Hirst, J. The deactive form of respiratory complex I from mammalian mitochondria is a Na+/H+ antiporter. J. Biol. Chem. 287, 34743-34751 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34743-34751
-
-
Roberts, P.G.1
Hirst, J.2
-
61
-
-
0037072803
-
The respiratory complex i (NDH-1) from Klebsiella pneumoniae, a sodium pump
-
Gemperli, A. C., Dimroth, P. & Steuber, J. The respiratory complex I (NDH-1) from Klebsiella pneumoniae, a sodium pump. J. Biol. Chem. 277, 33811-33817 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33811-33817
-
-
Gemperli, A.C.1
Dimroth, P.2
Steuber, J.3
-
62
-
-
0028972337
-
Strange bedfellows: Interactions between acidic side-chains in proteins
-
Flocco, M. M. & Mowbray, S. L. Strange bedfellows: interactions between acidic side-chains in proteins. J. Mol. Biol. 254, 96-105 (1995).
-
(1995)
J. Mol. Biol.
, vol.254
, pp. 96-105
-
-
Flocco, M.M.1
Mowbray, S.L.2
-
63
-
-
84872332798
-
Energy-converting respiratory complex I: On the way to the molecular mechanism of the proton pump
-
Verkhovskaya, M. & Bloch, D. A. Energy-converting respiratory complex I: on the way to the molecular mechanism of the proton pump. Int. J. Biochem. Cell Biol. 45, 491-511 (2013).
-
(2013)
Int. J. Biochem. Cell Biol.
, vol.45
, pp. 491-511
-
-
Verkhovskaya, M.1
Bloch, D.A.2
-
64
-
-
84883180274
-
Energy transducing roles of antiporter-like subunits in Escherichia coli NDH-1 with main focus on subunit NuoN (ND2)
-
Sato, M., Sinha, P. K., Torres-Bacete, J., Matsuno-Yagi, A. & Yagi, T. Energy transducing roles of antiporter-like subunits in Escherichia coli NDH-1 with main focus on subunit NuoN (ND2). J. Biol. Chem. 288, 24705-24716 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 24705-24716
-
-
Sato, M.1
Sinha, P.K.2
Torres-Bacete, J.3
Matsuno-Yagi, A.4
Yagi, T.5
-
65
-
-
84900514379
-
Electrostatics hydration, and proton transfer dynamics in the membrane domain of respiratory complex i
-
Kaila, V. R., Wikstrom, M. & Hummer, G. Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I. Proc. Natl Acad. Sci. USA 111, 6988-6993 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 6988-6993
-
-
Kaila, V.R.1
Wikstrom, M.2
Hummer, G.3
-
67
-
-
80051601805
-
A two-state stabilization-change mechanism for proton-pumping complex i
-
Brandt, U. A two-state stabilization-change mechanism for proton-pumping complex I. Biochim Biophys. Acta 1807, 1364-1369 (2011).
-
(2011)
Biochim Biophys. Acta
, vol.1807
, pp. 1364-1369
-
-
Brandt, U.1
-
68
-
-
84906343049
-
The mechanism of coupling between electron transfer and proton translocation in respiratory complex i
-
Sazanov, L. A. The mechanism of coupling between electron transfer and proton translocation in respiratory complex I. J. Bioenerg. Biomembr. 46, 247-253 (2014).
-
(2014)
J. Bioenerg. Biomembr.
, vol.46
, pp. 247-253
-
-
Sazanov, L.A.1
-
69
-
-
77957107068
-
A new hypothesis on the simultaneous direct and indirect proton pump mechanisms in NADH-quinone oxidoreductase (complex I)
-
Ohnishi, T., Nakamaru-Ogiso, E. & Ohnishi, S. T. A new hypothesis on the simultaneous direct and indirect proton pump mechanisms in NADH-quinone oxidoreductase (complex I). FEBS Lett. 584, 4131-4137 (2010).
-
(2010)
FEBS Lett.
, vol.584
, pp. 4131-4137
-
-
Ohnishi, T.1
Nakamaru-Ogiso, E.2
Ohnishi, S.T.3
-
70
-
-
51049093616
-
Identification of the mitochondrial ND3 subunit as a structural component involved in the active/deactive enzyme transition of respiratory complex i
-
Galkin, A. et al. Identification of the mitochondrial ND3 subunit as a structural component involved in the active/deactive enzyme transition of respiratory complex I. J. Biol. Chem. 283, 20907-20913 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 20907-20913
-
-
Galkin, A.1
-
71
-
-
78649496491
-
The membrane subunit NuoL (ND5) is involved in the indirect proton pumping mechanism of Escherichia coli complex i
-
Nakamaru-Ogiso, E. et al. The membrane subunit NuoL (ND5) is involved in the indirect proton pumping mechanism of Escherichia coli complex I. J. Biol. Chem. 285, 39070-39078 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 39070-39078
-
-
Nakamaru-Ogiso, E.1
-
72
-
-
80053201927
-
Structural contribution of C-Terminal segments of NuoL (ND5) and NuoM (ND4) subunits of complex i from
-
Torres-Bacete, J., Sinha, P. K., Matsuno-Yagi, A. & Yagi, T. Structural contribution of C-Terminal segments of NuoL (ND5) and NuoM (ND4) subunits of complex I from Escherichia coli. J. Biol. Chem. 286, 34007-34014 (2011).
-
(2011)
Escherichia Coli. J. Biol. Chem.
, vol.286
, pp. 34007-34014
-
-
Torres-Bacete, J.1
Sinha, P.K.2
Matsuno-Yagi, A.3
Yagi, T.4
-
73
-
-
82155168224
-
Probing the mechanistic role of the long a-helix in subunit L of respiratory complex i from Escherichia coli by site-directed mutagenesis
-
Belevich, G., Knuuti, J., Verkhovsky, M. I., Wikstrom, M. & Verkhovskaya, M. Probing the mechanistic role of the long a-helix in subunit L of respiratory complex I from Escherichia coli by site-directed mutagenesis. Mol. Microbiol. 82, 1086-1095 (2011).
-
(2011)
Mol. Microbiol.
, vol.82
, pp. 1086-1095
-
-
Belevich, G.1
Knuuti, J.2
Verkhovsky, M.I.3
Wikstrom, M.4
Verkhovskaya, M.5
-
74
-
-
84858698111
-
Asp563 of the horizontal helix of subunit NuoL is involved in proton translocation by the respiratory complex i
-
Steimle, S. et al. Asp563 of the horizontal helix of subunit NuoL is involved in proton translocation by the respiratory complex I. FEBS Lett. 586, 699-704 (2012).
-
(2012)
FEBS Lett.
, vol.586
, pp. 699-704
-
-
Steimle, S.1
-
75
-
-
0032490091
-
Human complex i defects in neurodegenerative diseases
-
Schapira, A. H. Human complex I defects in neurodegenerative diseases. Biochim. Biophys. Acta 1364, 261-270 (1998).
-
(1998)
Biochim. Biophys. Acta
, vol.1364
, pp. 261-270
-
-
Schapira, A.H.1
-
76
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy, M. P. How mitochondria produce reactive oxygen species. Biochem. J. 417, 1-13 (2009).
-
(2009)
Biochem. J.
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
77
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson, T. M. & Dawson, V. L. Molecular pathways of neurodegeneration in Parkinson's disease. Science 302, 819-822 (2003).
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
78
-
-
13944278132
-
Mitochondria oxidants, and aging
-
Balaban, R. S., Nemoto, S. & Finkel, T. Mitochondria, oxidants, and aging. Cell 120, 483-495 (2005).
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
79
-
-
0026702249
-
Leber's hereditary optic neuropathy: A model for mitochondrial neurodegenerative diseases
-
Brown, M. D., Voljavec, A. S., Lott, M. T., MacDonald, I. & Wallace, D. C. Leber's hereditary optic neuropathy: a model for mitochondrial neurodegenerative diseases. FASEB J. 6, 2791-2799 (1992).
-
(1992)
FASEB J.
, vol.6
, pp. 2791-2799
-
-
Brown, M.D.1
Voljavec, A.S.2
Lott, M.T.3
MacDonald, I.4
Wallace, D.C.5
-
80
-
-
0025995774
-
Electron transfer properties of NADH:ubiquinone reductase in the ND1/3460 and the ND4/11778 mutations of the Leber hereditary optic neuroretinopathy (LHON)
-
Majander, A., Huoponen, K., Savontaus, M. L., Nikoskelainen, E. & Wikstrom, M. Electron transfer properties of NADH:ubiquinone reductase in the ND1/3460 and the ND4/11778 mutations of the Leber hereditary optic neuroretinopathy (LHON). FEBS Lett. 292, 289-292 (1991).
-
(1991)
FEBS Lett.
, vol.292
, pp. 289-292
-
-
Majander, A.1
Huoponen, K.2
Savontaus, M.L.3
Nikoskelainen, E.4
Wikstrom, M.5
-
81
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
Bonnet, S. et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 11, 37-51 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
-
82
-
-
84873412963
-
Metformin and cancer: From the old medicine cabinet to pharmacological pitfalls and prospects
-
Emami Riedmaier, A., Fisel, P., Nies, A. T., Schaeffeler, E. & Schwab, M. Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects. Trends Pharmacol. Sci. 34, 126-135 (2013).
-
(2013)
Trends Pharmacol. Sci.
, vol.34
, pp. 126-135
-
-
Emami Riedmaier, A.1
Fisel, P.2
Nies, A.T.3
Schaeffeler, E.4
Schwab, M.5
-
83
-
-
0016754421
-
The protonmotive Q cycle: A general formulation
-
Mitchell, P. The protonmotive Q cycle: a general formulation. FEBS Lett. 59, 137-139 (1975).
-
(1975)
FEBS Lett.
, vol.59
, pp. 137-139
-
-
Mitchell, P.1
-
84
-
-
33748885262
-
Towards the mechanism of proton pumping by the haem-copper oxidases
-
Wikstrom, M. & Verkhovsky, M. I. Towards the mechanism of proton pumping by the haem-copper oxidases. Biochim. Biophys. Acta 1757, 1047-1051 (2006).
-
(2006)
Biochim. Biophys. Acta
, vol.1757
, pp. 1047-1051
-
-
Wikstrom, M.1
Verkhovsky, M.I.2
-
85
-
-
2142697116
-
Energy-converting [NiFe] hydrogenases from archaea and extremophiles: Ancestors of complex i
-
Hedderich, R. Energy-converting [NiFe] hydrogenases from archaea and extremophiles: ancestors of complex I. J. Bioenerg. Biomembr. 36, 65-75 (2004).
-
(2004)
J. Bioenerg. Biomembr.
, vol.36
, pp. 65-75
-
-
Hedderich, R.1
-
86
-
-
79961032041
-
The evolution of respiratory chain complex i from a smaller last common ancestor consisting of 11 protein subunits
-
Moparthi, V. K. & Hagerhall, C. The evolution of respiratory chain complex I from a smaller last common ancestor consisting of 11 protein subunits. J. Mol. Evol. 72, 484-497 (2011).
-
(2011)
J. Mol. Evol.
, vol.72
, pp. 484-497
-
-
Moparthi, V.K.1
Hagerhall, C.2
-
87
-
-
0034637432
-
The respiratory complex i of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases
-
Friedrich, T. & Scheide, D. The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases. FEBS Lett. 479, 1-5 (2000).
-
(2000)
FEBS Lett.
, vol.479
, pp. 1-5
-
-
Friedrich, T.1
Scheide, D.2
-
88
-
-
35748930865
-
Structure/function relationships of [NiFe]-And [FeFe]-hydrogenases
-
Fontecilla-Camps, J. C., Volbeda, A., Cavazza, C. & Nicolet, Y. Structure/function relationships of [NiFe]-And [FeFe]-hydrogenases. Chem. Rev. 107, 4273-4303 (2007).
-
(2007)
Chem. Rev.
, vol.107
, pp. 4273-4303
-
-
Fontecilla-Camps, J.C.1
Volbeda, A.2
Cavazza, C.3
Nicolet, Y.4
-
89
-
-
84863955498
-
Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM
-
Baker, L. A., Watt, I. N., Runswick, M. J., Walker, J. E. & Rubinstein, J. L. Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM. Proc. Natl Acad. Sci. USA 109, 11675-11680 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 11675-11680
-
-
Baker, L.A.1
Watt, I.N.2
Runswick, M.J.3
Walker, J.E.4
Rubinstein, J.L.5
-
90
-
-
43749107283
-
Comparative protein structure modeling using Modeller
-
Eswar, N. et al. Comparative protein structure modeling using Modeller. Curr. Protoc. Bioinformatics 15, 5.6.1-5.6.30 (2006).
-
(2006)
Curr. Protoc. Bioinformatics
, vol.15
, pp. 561-563
-
-
Eswar, N.1
|