메뉴 건너뛰기




Volumn 113, Issue 10, 2015, Pages 1550-1557

A high-cholesterol diet enriched with polyphenols from Oriental plums (Prunus salicina) improves cognitive function and lowers brain cholesterol levels and neurodegenerative-related protein expression in mice

Author keywords

24 Hydroxycholesterol; Alzheimer's disease; Cholesterol; Neurodegeneration; Oriental plums; Amyloid

Indexed keywords

24 HYDROXYCHOLESTEROL; AMYLOID BETA PROTEIN; BETA SECRETASE 1; CHOLESTEROL DERIVATIVE; CHOLESTEROL HYDROXYLASE; MESSENGER RNA; OXYGENASE; POLYPHENOL; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; CHOLESTEROL; CHOLESTEROL 24-HYDROXYLASE; HYPOCHOLESTEROLEMIC AGENT; NERVE PROTEIN; NOOTROPIC AGENT; SECRETASE; STEROID MONOOXYGENASE;

EID: 84929835491     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114515000732     Document Type: Article
Times cited : (36)

References (33)
  • 1
    • 0142105914 scopus 로고    scopus 로고
    • Cholesterol: From heart attacks to Alzheimer's disease
    • Raffai RL & Weisgraber KH (2003) Cholesterol: from heart attacks to Alzheimer's disease. J Lipid Res 44, 1423-1430.
    • (2003) J Lipid Res , vol.44 , pp. 1423-1430
    • Raffai, R.L.1    Weisgraber, K.H.2
  • 2
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • Glenner GG & Wong CW (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120, 885-890.
    • (1984) Biochem Biophys Res Commun , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 3
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: The cholesterol connection
    • Puglielli L, Tanzi RE & Kovacs DM (2003) Alzheimer's disease: the cholesterol connection. Nat Neurosci 6, 345-351.
    • (2003) Nat Neurosci , vol.6 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 4
    • 0031976318 scopus 로고    scopus 로고
    • Serum total cholesterol, apolipoprotein e ∈4 allele, and Alzheimer's disease
    • Notkola IL, Sulkava R, Pekkanen J, et al. (1998) Serum total cholesterol, apolipoprotein E ∈4 allele, and Alzheimer's disease. Neuroepidemiology 17, 14-20.
    • (1998) Neuroepidemiology , vol.17 , pp. 14-20
    • Notkola, I.L.1    Sulkava, R.2    Pekkanen, J.3
  • 5
    • 0035826795 scopus 로고    scopus 로고
    • A fluid connection: Cholesterol and Abeta
    • Wolozin B (2001) A fluid connection: cholesterol and Abeta. Proc Natl Acad Sci U S A 98, 5371-5373.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 5371-5373
    • Wolozin, B.1
  • 6
    • 0033528279 scopus 로고    scopus 로고
    • The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells
    • Kolsch H, Lutjohann D, Tulke A, et al. (1999) The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells. Brain Res 818, 171-175.
    • (1999) Brain Res , vol.818 , pp. 171-175
    • Kolsch, H.1    Lutjohann, D.2    Tulke, A.3
  • 7
    • 0036736781 scopus 로고    scopus 로고
    • Do oxysterols control cholesterol homeostasis?
    • Bjorkhem I (2002) Do oxysterols control cholesterol homeostasis? J Clin Invest 110, 725-730.
    • (2002) J Clin Invest , vol.110 , pp. 725-730
    • Bjorkhem, I.1
  • 8
    • 0037052771 scopus 로고    scopus 로고
    • Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls
    • Schonknecht P, Lutjohann D, Pantel J, et al. (2002) Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls. Neurosci Lett 324, 83-85.
    • (2002) Neurosci Lett , vol.324 , pp. 83-85
    • Schonknecht, P.1    Lutjohann, D.2    Pantel, J.3
  • 9
    • 28444463999 scopus 로고    scopus 로고
    • The beneficial effects of fruit polyphenols on brain aging
    • Lau FC, Shukitt-Hale B & Joseph JA (2005) The beneficial effects of fruit polyphenols on brain aging. Neurobiol Aging 26, 128-132.
    • (2005) Neurobiol Aging , vol.26 , pp. 128-132
    • Lau, F.C.1    Shukitt-Hale, B.2    Joseph, J.A.3
  • 10
    • 84910133976 scopus 로고    scopus 로고
    • Consumption of oriental plums improved the cognitive performance and modulated the cerebral neurodegeneration-related protein expressions in rats with nicotinamide/streptozotocininduced diabetes
    • Kao-Ting L, Yue-Hwa C, Ching-I L, et al. (2013) Consumption of oriental plums improved the cognitive performance and modulated the cerebral neurodegeneration-related protein expressions in rats with nicotinamide/streptozotocininduced diabetes. Food Nutr Sci 4, 1145-1154.
    • (2013) Food Nutr Sci , vol.4 , pp. 1145-1154
    • Kao-Ting, L.1    Yue-Hwa, C.2    Ching-I, L.3
  • 11
    • 11144335228 scopus 로고    scopus 로고
    • Apple phytochemicals and their health benefits
    • Boyer J & Liu RH (2004) Apple phytochemicals and their health benefits. Nutr J 3, 5.
    • (2004) Nutr J , vol.3 , pp. 5
    • Boyer, J.1    Liu, R.H.2
  • 12
    • 33645509490 scopus 로고    scopus 로고
    • Dosedependent hypocholesterolemic actions of dietary apple polyphenol in rats fed cholesterol
    • Osada K, Suzuki T, Kawakami Y, et al. (2006) Dosedependent hypocholesterolemic actions of dietary apple polyphenol in rats fed cholesterol. Lipids 41, 133-139.
    • (2006) Lipids , vol.41 , pp. 133-139
    • Osada, K.1    Suzuki, T.2    Kawakami, Y.3
  • 13
    • 79952119920 scopus 로고    scopus 로고
    • Troxerutin protects against high cholesterol-induced cognitive deficits in mice
    • Lu J, Wu D-M, Zheng Z-H, et al. (2011) Troxerutin protects against high cholesterol-induced cognitive deficits in mice. Brain 134, 783-797.
    • (2011) Brain , vol.134 , pp. 783-797
    • Lu, J.1    Wu, D.-M.2    Zheng, Z.-H.3
  • 14
    • 33846461062 scopus 로고    scopus 로고
    • Morris water maze: Procedures for assessing spatial and related forms of learning and memory
    • Vorhees CV & Williams MT (2006) Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc 1, 848-858.
    • (2006) Nat Protoc , vol.1 , pp. 848-858
    • Vorhees, C.V.1    Williams, M.T.2
  • 15
    • 0032253485 scopus 로고    scopus 로고
    • Simple assay for the level of total lipid peroxides in serum or plasma
    • Yagi K (1998) Simple assay for the level of total lipid peroxides in serum or plasma. Methods Mol Biol 108, 101-106.
    • (1998) Methods Mol Biol , vol.108 , pp. 101-106
    • Yagi, K.1
  • 16
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M & Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226, 497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 17
    • 45249117903 scopus 로고    scopus 로고
    • High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
    • Thirumangalakudi L, Prakasam A, Zhang R, et al. (2008) High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J Neurochem 106, 475-485.
    • (2008) J Neurochem , vol.106 , pp. 475-485
    • Thirumangalakudi, L.1    Prakasam, A.2    Zhang, R.3
  • 18
    • 0033833354 scopus 로고    scopus 로고
    • Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
    • Refolo LM, Malester B, LaFrancois J, et al. (2000) Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7, 321-331.
    • (2000) Neurobiol Dis , vol.7 , pp. 321-331
    • Refolo, L.M.1    Malester, B.2    Lafrancois, J.3
  • 19
    • 0029932417 scopus 로고    scopus 로고
    • Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties
    • Bouillot C, Prochiantz A, Rougon G, et al. (1996) Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties. J Biol Chem 271, 7640-7644.
    • (1996) J Biol Chem , vol.271 , pp. 7640-7644
    • Bouillot, C.1    Prochiantz, A.2    Rougon, G.3
  • 20
    • 84860832039 scopus 로고    scopus 로고
    • Regulation of cerebral cholesterol metabolism in Alzheimer disease
    • Reiss AB & Voloshyna I (2012) Regulation of cerebral cholesterol metabolism in Alzheimer disease. J Invest Med 60, 576-582.
    • (2012) J Invest Med , vol.60 , pp. 576-582
    • Reiss, A.B.1    Voloshyna, I.2
  • 21
    • 84866687889 scopus 로고    scopus 로고
    • Hypercholesterolemia accelerates intraneuronal accumulation of Abeta oligomers resulting in memory impairment in Alzheimer's disease model mice
    • Umeda T, Tomiyama T, Kitajima E, et al. (2012) Hypercholesterolemia accelerates intraneuronal accumulation of Abeta oligomers resulting in memory impairment in Alzheimer's disease model mice. Life Sci 91, 1169-1176.
    • (2012) Life Sci , vol.91 , pp. 1169-1176
    • Umeda, T.1    Tomiyama, T.2    Kitajima, E.3
  • 22
    • 33645240965 scopus 로고    scopus 로고
    • Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1) marked insensitivity toward different regulatory axes
    • Ohyama Y, Meaney S, Heverin M, et al. (2006) Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1) marked insensitivity toward different regulatory axes. J Biol Chem 281, 3810-3820.
    • (2006) J Biol Chem , vol.281 , pp. 3810-3820
    • Ohyama, Y.1    Meaney, S.2    Heverin, M.3
  • 23
    • 67650674085 scopus 로고    scopus 로고
    • Oxidative stress related changes in the brain of hypercholesterolemic rabbits
    • Aytan N, Tamtürk F, Kartal-özera N, et al. (2008) Oxidative stress related changes in the brain of hypercholesterolemic rabbits. Biofactors 33, 225-236.
    • (2008) Biofactors , vol.33 , pp. 225-236
    • Aytan, N.1    Tamtürk, F.2    Kartal-Özera, N.3
  • 24
    • 67650751079 scopus 로고    scopus 로고
    • Cholesterol 24-hydroxylase: An enzyme of cholesterol turnover in the brain
    • Russell DW, Halford RW, Ramirez DM, et al. (2009) Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain. Annu Rev Biochem 78, 1017-1040.
    • (2009) Annu Rev Biochem , vol.78 , pp. 1017-1040
    • Russell, D.W.1    Halford, R.W.2    Ramirez, D.M.3
  • 25
    • 33751096969 scopus 로고    scopus 로고
    • Crossing the barrier: Oxysterols as cholesterol transporters and metabolic modulators in the brain
    • Björkhem I (2006) Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. J Intern Med 260, 493-508.
    • (2006) J Intern Med , vol.260 , pp. 493-508
    • Björkhem, I.1
  • 26
    • 0842303768 scopus 로고    scopus 로고
    • Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease
    • Heverin M, Bogdanovic N, Lütjohann D, et al. (2004) Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease. J Lipid Res 45, 186-193.
    • (2004) J Lipid Res , vol.45 , pp. 186-193
    • Heverin, M.1    Bogdanovic, N.2    Lütjohann, D.3
  • 27
    • 1642525647 scopus 로고    scopus 로고
    • Diagnostic use of cerebral and extracerebral oxysterols
    • Leoni V, Masterman T, Mousavi FS, et al. (2004) Diagnostic use of cerebral and extracerebral oxysterols. Clin Chem Lab Med 42, 186-191.
    • (2004) Clin Chem Lab Med , vol.42 , pp. 186-191
    • Leoni, V.1    Masterman, T.2    Mousavi, F.S.3
  • 28
    • 0141700567 scopus 로고    scopus 로고
    • Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers
    • Leoni V, Masterman T, Patel P, et al. (2003) Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers. J Lipid Res 44, 793-799.
    • (2003) J Lipid Res , vol.44 , pp. 793-799
    • Leoni, V.1    Masterman, T.2    Patel, P.3
  • 29
    • 0031955298 scopus 로고    scopus 로고
    • Silymarin inhibits the development of diet-induced hypercholesterolemia in rats
    • Krecman V, Skottova N, Walterova D, et al. (1998) Silymarin inhibits the development of diet-induced hypercholesterolemia in rats. Planta Med 64, 138-142.
    • (1998) Planta Med , vol.64 , pp. 138-142
    • Krecman, V.1    Skottova, N.2    Walterova, D.3
  • 30
    • 17144387483 scopus 로고    scopus 로고
    • Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementation
    • Gorinstein S, Leontowicz H, Leontowicz M, et al. (2005) Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementation. J Agric Food Chem 53, 3223-3228.
    • (2005) J Agric Food Chem , vol.53 , pp. 3223-3228
    • Gorinstein, S.1    Leontowicz, H.2    Leontowicz, M.3
  • 31
    • 84655167890 scopus 로고    scopus 로고
    • Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease
    • Williams RJ & Spencer JP (2012) Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease. Free Radic Biol Med 52, 35-45.
    • (2012) Free Radic Biol Med , vol.52 , pp. 35-45
    • Williams, R.J.1    Spencer, J.P.2
  • 32
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • Reagan-Shaw S, Nihal M & Ahmad N (2008) Dose translation from animal to human studies revisited. FASEB J 22, 659-661.
    • (2008) FASEB J , vol.22 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 33
    • 84885338948 scopus 로고    scopus 로고
    • Dried plums and their products: Composition and health effects - An updated review
    • Stacewicz-Sapuntzakis M (2013) Dried plums and their products: composition and health effects - an updated review. Crit Rev Food Sci Nutr 53, 1277-1302.
    • (2013) Crit Rev Food Sci Nutr , vol.53 , pp. 1277-1302
    • Stacewicz-Sapuntzakis, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.