Oxidative Stress-Related Genes in Type 2 Diabetes: Association Analysis and Their Clinical Impact

Biochemical Genetics

Volumn 53, Issue 4-6, 2015, Pages 93-119

  Haldar, Suranjana Ray ^a   Chakrabarty, Arpita ^b   Chowdhury, Subhankar ^b   Haldar, Atish ^c   Sengupta, Sanghamitra ^a   Bhattacharyya, Maitree ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^c CALCUTTA NATIONAL MEDICAL COLLEGE   (India)

Author keywords

Association; Diabetes; Oxidative stress; Paraoxonase; RAGE; ROS; SOD

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; ARYLDIALKYLPHOSPHATASE 1; ARYLDIALKYLPHOSPHATASE 2; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXTRACELLULAR SUPEROXIDE DISMUTASE; GLUCOSE; HEMOGLOBIN A1C; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN; PROTEIN AKR1B1; PROTEIN CYBA1; UNCLASSIFIED DRUG; ARYLDIALKYLPHOSPHATASE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN; PON1 PROTEIN, HUMAN; PON2 PROTEIN, HUMAN;

ADULT; ARTICLE; CONTROLLED STUDY; DIABETIC PATIENT; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PHENOTYPE; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; BODY MASS; GENETIC ASSOCIATION STUDY; GENETICS; GLUCOSE BLOOD LEVEL; GLYCOSYLATION; METABOLISM;

ALLELES; ARYLDIALKYLPHOSPHATASE; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD GLUCOSE; BODY MASS INDEX; DIABETES MELLITUS, TYPE 2; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLYCOSYLATION; HAPLOTYPES; HEMOGLOBINS; HUMANS; OXIDATIVE STRESS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84929688090     PISSN: 00062928     EISSN: 15734927     Source Type: Journal    
DOI: 10.1007/s10528-015-9675-z     Document Type: Article

References (43)

1. Adak S, Sengupta S, Chowdhury S, Bhattacharyya M (2010) Co existence of risk and protective haplotypes of Calpain 10 gene to type 2 diabetes in the eastern Indian population. Diab Vasc Dis Res 7:63–68
2. Agrawal S, Tripathi G, Prajnya R, Sinha N, Gilmour A, Bush L, Mastana S (2009) Paraxonase 1 gene polymorphisms contribute to coronary artery disease risk among north Indians. Ind J Med Sci 63:335–344
3. Altuner D, Suzen SH, Ates I, Koc GV, Aral Y et al (2011) Are PON1 Q/R 192 and M/L 55 polymorphisms risk factors for diabetes complications in Turkish population? Clin Biochem 44:372–376
4. Banerjee M, Saxena M (2012) An overview and molecular genetics of type 2 diabetes mellitus. In: Caplis I, Frangopoulos S (eds) Type 2 diabetes mellitus: causes, treatment and preventive strategies. Nova Science Publishers, New York
5. Baragetti I, Norata D, Sarcina C et al (2013) 374 T/A RAGE polymorphism is associated with chronic kidney disease progression in subjects affected by nephrocardiovascular disease. PLoS One 8:e0060089
6. Brownlee M (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414:813–820
7. Chen H, Li X, Epstein PN (2005) MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. Diabetes 54:1437–1446
8. Costa LG, Cole TB, Jarvik GP, Furlong CE (2003) Functional genomics of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annu Rev Med 54:371–392
9. DeFronzo RA (1997) Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 5:177–269
10. Del Prato S, Marchetti P (2004) Beta and alpha-cell dysfunction in type 2 diabetes. Horm Metab Res 36:775–781
11. Donaghue KC, Margan SH, Chan AK, Holloway B, Silink M, Rangel T, Bennetts B (2005) The association of aldose reductase gene (AKR1B1) polymorphisms with diabetic neuropathy in adolescents. Diabet Med 22:1315–1320
12. Ergun MA, Yurtcu E, Demirci H, Ilhan MN, Barkar V et al (2011) PON1 55 and 192 gene polymorphisms in type 2 diabetes mellitus patients in a Turkish population. Biochem Genet 49:1–8
13. Haber CA, Lam TK, Yu Z, Gupta N, Goh T, Bogdanovic E, Giacca A, Fantus IG (2003) N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress. Am J Physiol Endocrinol Metab 285:E744–E753
14. Kankova K, Sebekova K (2005) Genetic variability in the RAGE gene: possible implications for nutrigenetics, nutrigenomics, and understanding the susceptibility to diabetic complications. Mol Nutr Food Res 49:700–709
15. King GL, Loeken MR (2004) Hyperglycemia-induced oxidative stress in diabetic complications. Histochem Cell Biol 122:333–338
16. Koya D, King GL (1998) Protein kinase C activation and the development of diabetic complications. Diabetes 47:859–866
17. Leon CA, Raij L (2005) Interaction of haemodynamic and metabolic pathways in the genesis of diabetic nephropathy. J Hypertens 23:1931–1937
18. Maiese K, Morhan SD, Chong ZZ (2007) Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus. Curr Neurovasc Res 4:63–71
19. Makiishi T, Araki S, Koya D, Maeda S, Kashiwagi A, Haneda M (2003) C-106T polymorphism of AKR1B1 is associated with diabetic nephropathy and erythrocyte aldose reductase content in Japanese subjects with type 2 diabetes mellitus. Am J Kidney Dis 42:943–951
20. Matsunaga-Irie S, Maruyama T, Yamamoto Y et al (2004) Relation between development of nephropathy and the p22phox C242T and receptor for advanced glycation end product G1704T gene polymorphisms in type 2 diabetic patients. Diabet Care 27:303–307
21. Mayer B, Hemmens B (1997) Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 22:477–481
22. McGarry JD (2002) Banting Lecture 2001. Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 51:7–18
23. Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16(3):1215
24. Moore DJ, Gregory JM, Kumah-crystal YA, Simmons JH (2009) Mitigating micro- and macro-vascular complications of diabetes beginning in adolescence. Vasc Health Risk Manag 5:1015–1031
25. Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M (2000) Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404:787–790
26. Poitout V, Robertson RP (2002) Secondary beta-cell failure in type 2 diabetes—a convergence of glucotoxicity and lipotoxicity. Endocrinology 143:339–342
27. Prasad P, Tiwari AK, Prasanna K, Ammini AC, Gupta A, Gupta R, Thelma BK (2010) Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes. BMC Med Genet 11:52
28. Rachek LI, Thornley NP, Grishko VI, LeDoux SP, Wilson GL (2006) Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria. Diabetes 55:1022–1028
29. Ramprasad S, Radha V, Mathias RA, Majumder PP, Rao MRS, Rema M (2007) RAGE gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India. Eye 21:395–401
30. Ray Haldar S, Bhattacharyya M (2014) Lipid peroxidation products as predictors in disease progression. J Exp Integr Med 4:151–164
31. Richter RJ, Jarvik GP, Furlong CE (2010) Paraoxonase 1 status as a risk factor for disease or exposure. Adv Exp Med Biol 660:29–35
32. Rosen P, Nawroth PP, King G, Moller W, Tritschler HJ, Packer L (2001) The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCOMCBN, the American Diabetes Association, and the German Diabetes Society. Diabetes Metab Res Rev 17:189–212
33. Shadman Z, Khoshniat M, Poorsoltan N et al (2013) Association of high carbohydrate versus high fat diet with glycated haemoglobin in high calorie consuming type 2 diabetics. J Diabetes Metab Disord 12:27
34. Sheetz MJ, King GL (2002) Molecular understanding of hyperglycemia’s adverse effects for diabetic complications. J Am Med Assoc 288:2579–2588
35. Sivenius K, Niskanen L, Voutilainen-Kaunisto R, Laakso M, Uusitupa M (2004) Aldose reductase gene polymorphisms and susceptibility to microvascular complications in Type 2 diabetes. Diabet Med 21:1325–1333
36. Stevens MJ, Obrosova I, Feldman EL, Greene DA (2000) The sorbitol-osmotic and sorbitol-redox hypothesis. In: LeRoith D, Taylor SI, Olefsky JM (eds) Diabetes mellitus: a fundamental and clinical text. Lippincott Williams & Wilkins, Philadelphia
37. Tanus-Santos JE, Desai M, Flockhart DA (2001) Effect of ethnicity on the distribution of clinically relevant endothelial nitric oxide variants. Pharmacogenetics 11:719–725
38. Thameem F, Puppala S, Arar NH, Stern MP, Blangero J, Duggirala R, Abboud HE (2008) Endothelial nitric oxide synthase (eNOS) gene polymorphisms and their association with type 2 diabetes-related traits in Mexican Americans. Diab Vasc Dis Res 5:109–113
39. Tiwari AK, Prasad P, Thelma BK, Prasanna Kumar KM, Ammini AC, Gupta A, Gupta R (2009) Oxidative stress pathway genes and chronic renal insufficiency in Asian Indians with Type 2 diabetes. J Diabetes Complicat 23:102–111
40. Wang Y, Ng MC, Lee SC, So WY, Tong PC, Cockram CS, Critchley JA, Chan JC (2003) Phenotypic heterogeneity and associations of two aldose reductase gene polymorphisms with nephropathy and retinopathy in type 2 diabetes. Diabetes Care 26:2410–2415
41. Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27:1047–1053
42. Wolff SP, Dean RT (1987) Glucose autoxidation and protein modification: the potential role of autoxidative glycosylation’ in diabetes. Biochem J 245:243–250
43. Yano M, Hasegawa G, Ishii M, Yamasaki M, Fukui M, Nakamura N, Yoshikawa T (2004) Short-term exposure of high glucose concentration induces generation of reactive oxygen species in endothelial cells: implication for the oxidative stress associated with postprandial hyperglycemia. Redox Rep 9:111–116