-
3
-
-
1542723400
-
Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia
-
DOI 10.1073/pnas.0308750101
-
Chun CK, Ozer EA, Welsh MJ, Zabner J, Greenberg EP (2004) Inactivation of a Pseudomonas aeruginosa quorum sensing signal by human airway epithelia. Proc Natl Acad Sci USA 101:3587-3590 (Pubitemid 38338239)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.10
, pp. 3587-3590
-
-
Chun, C.K.1
Ozer, E.A.2
Welsh, M.J.3
Zabner, J.4
Greenberg, E.P.5
-
4
-
-
22944478632
-
Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism
-
Cole TB, Walter BJ, Shih DM, Tward AD, Lusis AJ, Timchalk C, Richter RJ, Costa LG, Furlong CE (2005) Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism. Pharmacogenet Genomics 15:589-598 (Pubitemid 41044245)
-
(2005)
Pharmacogenetics and Genomics
, vol.15
, Issue.8
, pp. 589-598
-
-
Cole, T.B.1
Walter, B.J.2
Shih, D.M.3
Tward, A.D.4
Lusis, A.J.5
Timchalk, C.6
Richter, R.J.7
Costa, L.G.8
Furlong, C.E.9
-
5
-
-
0025216933
-
Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats
-
DOI 10.1016/0041-008X(90)90263-T
-
Costa LG, McDonald BE, Murphy SD, Omenn GS, Richter RJ, Motulsky AG, Furlong CE (1990) Serum paraoxonase and its influence on paraoxon and chlorpyrifos-oxon toxicity in rats. Toxicol Appl Pharmacol 103:66-76 (Pubitemid 20115985)
-
(1990)
Toxicology and Applied Pharmacology
, vol.103
, Issue.1
, pp. 66-76
-
-
Costa, L.G.1
McDonald, B.E.2
Murphy, S.D.3
Omenn, G.S.4
Richter, R.J.5
Motulsky, A.G.6
Furlong, C.E.7
-
6
-
-
0030293198
-
The human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
-
Davies H, Richter RJ, Keifer M, Broomfield C, Sowalla J, Furlong CE (1996) The human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nature Genet 14: 334-336
-
(1996)
Nature Genet
, vol.14
, pp. 334-336
-
-
Davies, H.1
Richter, R.J.2
Keifer, M.3
Broomfield, C.4
Sowalla, J.5
Furlong, C.E.6
-
7
-
-
0038312083
-
Paraoxonase-1 promoter haplotypes and serum paraoxonase: A predominant role for polymorphic position - 107, implicating the Sp1 transcription factor
-
DOI 10.1042/BJ20021670
-
Deakin S, Leviev I, Brulhart-Meynet M-C, James RW (2003) Paraoxonase-1 promoter haplotypes and serum paraoxonase: a predominant role for polymorphic position ?107, implicating the Sp1 transcription factor. Biochem J 372:643-649 (Pubitemid 36723911)
-
(2003)
Biochemical Journal
, vol.372
, Issue.2
, pp. 643-649
-
-
Deakin, S.1
Leviev, I.2
Brulhart-Meynet, M.-C.3
James, R.W.4
-
8
-
-
8644281865
-
Genetic and environmental factors modulating serum concentrations and activities of the antioxidant enzyme paraoxonase-I
-
DOI 10.1042/CS20040187
-
Deakin SP, James RW(2004) Genetic and environmental factors modulating serum concentrations and activities of the antioxidant enzyme paraoxonase-1. Clin Sci (Lond. ) 107:435-447 (Pubitemid 39506735)
-
(2004)
Clinical Science
, vol.107
, Issue.5
, pp. 435-447
-
-
Deakin, S.P.1
James, R.W.2
-
10
-
-
59149094022
-
The functional consequences of polymorphisms in the human PON1 gene
-
Mackness B, Mackness M, Aviram M, Paragh G (eds), Development and Xenobiotic Metabolism. Dordrecht, The Netherlands: Springer
-
Furlong CE, Richter RJ, Li W-F, Brophy VH, Carlson C, Meider M, Nickerson D, Costa LG, Ranchalis J, Lusis AJ, Shih DM, Tward A, Jarvik GP (2008) The functional consequences of polymorphisms in the human PON1 gene. In: Mackness B, Mackness M, Aviram M, Paragh G (eds). The Paraoxonases: Their Role in Disease, Development and Xenobiotic Metabolism. Dordrecht, The Netherlands: Springer. 267-281
-
(2008)
The Paraoxonases: Their Role in Disease
, pp. 267-281
-
-
Furlong, C.E.1
Richter, R.J.2
Li, W.-F.3
Brophy, V.H.4
Carlson, C.5
Meider, M.6
Nickerson, D.7
Costa, L.G.8
Ranchalis, J.9
Lusis, A.J.10
Shih, D.M.11
Tward, A.12
Jarvik, G.P.13
-
11
-
-
33644604127
-
PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity
-
Furlong C, Holland N, Richter R, Bradman A, Ho A, Eskenazi B (2006) PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenet Genomics 16:183-190
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 183-190
-
-
Furlong, C.1
Holland, N.2
Richter, R.3
Bradman, A.4
Ho, A.5
Eskenazi, B.6
-
12
-
-
33748546980
-
A long and winding road: Defining the biological role and clinical importance of paraoxonases
-
DOI 10.1515/CCLM.2006.207, PII CCLM4491052
-
James RW. (2006) A long and winding road: defining the biological role and clinical importance of paraoxonases. Clin Chem Lab Med 44:1052-1059 (Pubitemid 44370921)
-
(2006)
Clinical Chemistry and Laboratory Medicine
, vol.44
, Issue.9
, pp. 1052-1059
-
-
James, R.W.1
-
13
-
-
0033758531
-
Paraoxonase phenotype is a better predictor of vascular disease than PON1192 or PON155 genotype
-
Jarvik GP, Rozek LS, Brophy VH, Hatsukami TS, Richter RJ, Schellenberg GD, Furlong CE (2000) Paraoxonase phenotype is a better predictor of vascular disease than PON1192 or PON155 genotype. Atheroscler Thromb Vasc Biol 20:2442-2447
-
(2000)
Atheroscler Thromb Vasc Biol
, vol.20
, pp. 2442-2447
-
-
Jarvik, G.P.1
Rozek, L.S.2
Brophy, V.H.3
Hatsukami, T.S.4
Richter, R.J.5
Schellenberg, G.D.6
Furlong, C.E.7
-
14
-
-
0038579858
-
Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status
-
DOI 10.1097/00008571-200305000-00009
-
Jarvik GP, Jampsa R, Richter RJ, Carlson C, Rieder M, Nickerson D, Furlong CE (2003) Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status. Pharmacogenetics 13:291-295 (Pubitemid 36583997)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.5
, pp. 291-295
-
-
Jarvik, G.P.1
Jampsa, R.2
Richter, R.J.3
Carlson, C.S.4
Rieder, M.J.5
Nickerson, D.A.6
Furlong, C.E.7
-
15
-
-
0042233509
-
Future studies of low-activity PON1 phenotype subjects may reveal how PON1 protects against cardiovascular disease
-
DOI 10.1161/01.ATV.0000082600.42562.7F
-
La Du BN (2003) Future studies of low-activity PON1 phenotype subjects may reveal how PON1 protects against cardiovascular disease, Arterioscler Thromb Vasc Biol 23:1317-1318 (Pubitemid 36994516)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.8
, pp. 1317-1318
-
-
La Du, B.N.1
-
16
-
-
23644439454
-
The association of the PON1 Q192R polymorphism with coronary heart disease: Findings from the British Women's Heart and Health cohort study and a meta-analysis
-
Lawlor DA, Day IN, Gaunt TR, Hinks LJ, Briggs PJ, KiesslingM, Timpson N, Smith GD, Ebrahim S (2004) The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis. BMC Genet 5:17
-
(2004)
BMC Genet
, vol.5
, pp. 17
-
-
Lawlor, D.A.1
Day, I.N.2
Gaunt, T.R.3
Hinks, L.J.4
Briggs, P.J.5
Kiessling, M.6
Timpson, N.7
Smith, G.D.8
Ebrahim, S.9
-
18
-
-
0028958850
-
Paraoxonase protects against chlorpyrifos toxicity in mice
-
Li W-F, Furlong CE, Costa LG (1995) Paraoxonase protects against chlorpyrifos toxicity in mice. Toxicol Lett 76:219-226
-
(1995)
Toxicol Lett
, vol.76
, pp. 219-226
-
-
Li, W.-F.1
Furlong, C.E.2
Costa, L.G.3
-
19
-
-
0034524737
-
Catalytic efficiency determines the in vivo efficacy of PON1 for detoxifying organophosphates
-
Li W-F, Costa LG, Richter RJ, Hagen T, Shih DM, Tward A, Lusis AJ, Furlong CE (2000) Catalytic efficiency determines the in vivo efficacy of PON1 for detoxifying organophosphates. Pharmacogenetics 10:767-780
-
(2000)
Pharmacogenetics
, vol.10
, pp. 767-780
-
-
Li, W.-F.1
Costa, L.G.2
Richter, R.J.3
Hagen, T.4
Shih, D.M.5
Tward, A.6
Lusis, A.J.7
Furlong, C.E.8
-
20
-
-
0035574446
-
Paraoxonase status in coronary heart disease: Are activity and concentration more important than genotype?
-
Mackness B, Davies GK, Turkie W, Lee E, Roberts DH, Hill E, Roberts C, Durrington PN, Mackness MI (2001) Paraoxonase status in coronary heart disease: are activity and concentration more important than genotype? Arterioscler Thromb Vasc Biol 21:1451-1457 (Pubitemid 34219807)
-
(2001)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.21
, Issue.9
, pp. 1451-1457
-
-
Mackness, B.1
Davies, G.K.2
Turkie, W.3
Lee, E.4
Roberts, D.H.5
Hill, E.6
Roberts, C.7
Durrington, P.N.8
Mackness, M.I.9
-
21
-
-
27744436315
-
Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing
-
DOI 10.1016/j.femsle.2005.09.023, PII S0378109705006555
-
Ozer EA, Pezzulo A, Shih DM, Chun C, Furlong C, Lusis AJ, Greenberg EP, Zabner J (2005) Human and murine Paraoxonase 1 are host modulators of P. aeruginosa quorum-sensing. FEMS Microbiol Lett 253:29-37 (Pubitemid 41605391)
-
(2005)
FEMS Microbiology Letters
, vol.253
, Issue.1
, pp. 29-37
-
-
Ozer, E.A.1
Pezzulo, A.2
Shih, D.M.3
Chun, C.4
Furlong, C.5
Lusis, A.J.6
Greenberg, E.P.7
Zabner, J.8
-
22
-
-
0033461179
-
Determination of paraoxonase (PON1) status requires more than genotyping
-
Richter RJ, Furlong CE (1999) Determination of paraoxonase (PON1) status requires more than genotyping. Pharmacogenetics 9:745-753 (Pubitemid 30011938)
-
(1999)
Pharmacogenetics
, vol.9
, Issue.6
, pp. 745-753
-
-
Richter, R.J.1
Furlong, C.E.2
-
23
-
-
59149094487
-
Determination of paraoxonase 1 status without the use of toxic organophosphate substrates
-
DOI: 10.1161/CIRCGENETICS.108.811638
-
Richter RJ, Jarvik GP, Furlong CE (2008) Determination of paraoxonase 1 status without the use of toxic organophosphate substrates. Circ Cardiovasc Genet 1:147-152 DOI: 10.1161/CIRCGENETICS.108.811638
-
(2008)
Circ Cardiovasc Genet
, vol.1
, pp. 147-152
-
-
Richter, R.J.1
Jarvik, G.P.2
Furlong, C.E.3
-
25
-
-
0032537833
-
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
-
DOI 10.1038/28406
-
Shih DM, Gu L, Xia Y-R, Navab M, Li W-F, Hama S, Castellani LW, Furlong CE, Costa, LG, Fogelman AM, Lusis AJ (1998) Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis. Nature 394:284-287 (Pubitemid 28335041)
-
(1998)
Nature
, vol.394
, Issue.6690
, pp. 284-287
-
-
Shih, D.M.1
Gu, L.2
Xia, Y.-R.3
Navab, M.4
Li, W.-F.5
Hama, S.6
Castellani, L.W.7
Furlong, C.E.8
Costa, L.G.9
Fogelman, A.M.10
Lusis, A.J.11
-
26
-
-
51349160074
-
Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1
-
doi:10.1172/JCI35147
-
Stoltz DA, Ozer EA, Taft PJ, Barry M, Liu L, Kiss PJ, Moninger TO, Parsek MR, Zabner J (2008) Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1. J Clin Invest 118:3123-3131 doi:10.1172/JCI35147
-
(2008)
J Clin Invest
, vol.118
, pp. 3123-3131
-
-
Stoltz, D.A.1
Ozer, E.A.2
Taft, P.J.3
Barry, M.4
Liu, L.5
Kiss, P.J.6
Moninger, T.O.7
Parsek, M.R.8
Zabner, J.9
-
27
-
-
1542331537
-
Four paraoxonase gene polymorphisms in 11 212 cases of coronary heart disease and 12 786 controls: Meta-analysis of 43 studies
-
DOI 10.1016/S0140-6736(04)15642-0, PII S0140673604156420
-
Wheeler JG, Keavney BD, Watkins H, Collins R, Danesh J (2004) Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies. Lancet 363:689-695. (Pubitemid 38296555)
-
(2004)
Lancet
, vol.363
, Issue.9410
, pp. 689-695
-
-
Wheeler, J.G.1
Keavney, B.D.2
Watkins, H.3
Collins, R.4
Danesh, J.5
|