Error-free and mutagenic processing of topoisomerase 1-provoked damage at genomic ribonucleotides

EMBO Journal

Volumn 34, Issue 9, 2015, Pages 1259-1269

  Sparks, Justin L ^a,b   Burgers, Peter M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

DNA repair; genomic ribonucleotides; mutagenesis; topoisomerase 1

Indexed keywords

2 NUCLEOTIDE; ADENOSINE DERIVATIVE; CYCLIC NUCLEOTIDE; DNA BINDING PROTEIN; DNA TOPOISOMERASE; NUCLEOTIDE DERIVATIVE; PHOSPHOPEPTIDE; RIBONUCLEOSIDE 2',3' CYCLIC PHOSPHATE; RIBONUCLEOSIDE DERIVATIVE; RIBONUCLEOTIDE; TDP1 PROTEIN; TPP1 PROTEIN; UNCLASSIFIED DRUG; DEOXYNUCLEOTIDE 3'-PHOSPHATASE; DNA; NUCLEOTIDASE; PHOSPHODIESTERASE; SACCHAROMYCES CEREVISIAE PROTEIN; TYROSYL-DNA PHOSPHODIESTERASE;

ARTICLE; BIOCHEMICAL ANALYSIS; CONTROLLED STUDY; COVALENT BOND; DINUCLEOTIDE REPEAT; DNA CLEAVAGE; DNA DAMAGE; DNA PROTEIN COMPLEX; DNA SEQUENCE; DNA STRUCTURE; ENZYME PURIFICATION; ENZYME RELEASE; EXCISION REPAIR; GENE DELETION; GENE OVEREXPRESSION; GENOME; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; RIBONUCLEOTIDE EXCISION REPAIR; SEQUENCE ALIGNMENT; CHEMISTRY; GENETICS; METABOLISM;

DINUCLEOTIDE REPEATS; DNA; DNA TOPOISOMERASES, TYPE I; NUCLEOTIDASES; PHOSPHORIC DIESTER HYDROLASES; RIBONUCLEOTIDES; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84929660851     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201490868     Document Type: Article

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