A novel function of Huntingtin in the cilium and retinal ciliopathy in Huntington's disease mice

Neurobiology of Disease

Volumn 80, Issue , 2015, Pages 15-28

  Karam, Alice ^a,b,c,d   Tebbe, Lars ^e   Weber, Chantal ^a,b,c,d   Messaddeq, Nadia ^a,b,c,d   Morlé, Laurette ^f   Kessler, Pascal ^a,b,c,d   Wolfrum, Uwe ^e   Trottier, Yvon ^a,b,c,d  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

^c INSERM   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e JOHANNES GUTENBERG UNIVERSITY   (Germany)

^f CENTRE DE GÉNÉTIQUE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Cilia; Huntingtin; Huntington's disease; Photoreceptor

Indexed keywords

ALPHA TUBULIN; CARRIER PROTEIN; HUNTINGTIN; IFT57 PROTEIN; IFT88 PROTEIN; UNCLASSIFIED DRUG; HUNTINGTON PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AXONEME; CELL DEATH; CENTRIOLE; CILIARY MOTILITY; CONTROLLED STUDY; EPENDYMA CELL; HUNTINGTON CHOREA; IMMUNOFLUORESCENCE MICROSCOPY; MOUSE; NONHUMAN; PATHOGENESIS; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETINA DISEASE; RETINAL CILIOPATHY; TUNEL ASSAY; ANIMAL; DISEASE MODEL; EUKARYOTIC FLAGELLUM; FEMALE; HEK293 CELL LINE; HUMAN; MALE; METABOLISM; MICROTUBULE; PATHOLOGY; PHOTORECEPTOR CELL; RETINA; TRANSGENIC MOUSE; ULTRASTRUCTURE;

ANIMALS; CILIA; DISEASE MODELS, ANIMAL; FEMALE; HEK293 CELLS; HUMANS; HUNTINGTON DISEASE; MALE; MICE; MICE, TRANSGENIC; MICROTUBULES; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOTORECEPTOR CELLS; RETINA;

EID: 84929612955     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.05.008     Document Type: Article

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