Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors

Investigative Ophthalmology and Visual Science

Volumn 43, Issue 1, 2002, Pages 22-32

  Liu, Q ^a   Zhou, J ^a   Daiger, S P ^a   Farber, D B ^a   Heckenlively, J R ^a   Smith, J E ^a   Sullivan, L S ^a   Zuo, J ^a   Milam, A H ^a   Pierce, E A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN RP1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE AMPLIFICATION; GENE EXPRESSION; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RETINA CONE; RETINITIS PIGMENTOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CATTLE; EYE PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE AMPLIFICATION; HUMANS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PHOTORECEPTORS, VERTEBRATE; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; RETINITIS PIGMENTOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036140012     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Prevalence of retinitis pigmentosa in Maine
2. Genetic heterogeneity of retinal degenerations and dysfunctions
3. Mutations in a gene encoding a new oxygen-regulated photoreceptor protein cause dominant retinitis pigmentosa
4. Mutations in a novel retina-specific gene cause autosomal dominant retinitis pigmentosa
5. A nonsense mutation in a novel gene is associated with retinitis pigmentosa in a family linked to the RP1 locus
6. Mutations within the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa
7. Mutations in the human retinal degeneration slow gene in autosomal dominant retinitis pigmentosa
8. A mutation in NRL is associated with autosomal dominant retinitis pigmentosa
9. Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein
10. Mutations in the RP1 gene causing autosomal dominant retinitis pigmentosa
11. Disease expression of RP1 mutations causing autosomal dominant retinitis pigmentosa
12. RP1 protein truncating mutations predominate at the RP1 adRP locus
13. Further screening of the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa
14. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
15. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
16. Evidence against the role of rhodopsin in rod outer segment binding to RPE cells
17. Cone properties of retinal margin cells in the monkey (Macaca mulatta)
18. The sensory cilium of retinal rods is analogous to the transitional zone of motile cilia
19. Fine structure of a periciliary ridge complex of frog retinal rod cells revealed by ultrahigh resolution scanning electron microscopy
20. Lengths of immunolabeled ciliary microtubules in frog photoreceptor outer segments
21. The doublet microtubules of rods of the rabbit retina
22. Rhodopsin trafficking and its role in retinal dystrophies
23. Cytoskeletal specializations at the rod photoreceptor distal tip
24. Immunocytochemical localization of opsin in the cell membrane of developing rat retinal photoreceptors
25. Molecular characterization of the retinal degeneration slow (rds) mutation in mouse
26. Morphological, physiological, and biochemical changes in rhodopsin knockout mice
27. Photoreceptor membrane proteins, phototransduction, and retinal degenerative diseases
28. Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to doublecortin
29. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
30. DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization
31. Patient mutations in doublecortin define a repeated tubulin-binding domain
32. Visual cells and the concept of renewal
33. Turnover of rod photoreceptor outer segments. I: Membrane addition and loss in relationship to temperature
34. Immunolocalization of 48K in rod photoreceptors: Light and ATP increase OS labeling
35. Transient, cyclic changes in mouse visual cell gene products during the light-dark cycle
36. Membrane assembly in retinal photoreceptors. III: Distinct membrane domains of the connecting cilium of developing rods
37. Rhodopsin transport in the membrane of the connecting cilium of mammalian photoreceptor cells
38. Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors
39. Association of myosin with the connecting cilium of rod photoreceptors
40. Defective myosin VIIA gene responsible for Usher syndrome type 1B
41. A retinitis pigmentosa GTPase regulator (RPGR): Interacting protein is stably associated with the photoreceptor ciliary axoneme and anchors RPGR to the connecting cilium
42. A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3)
43. Evidence for kinesin-related proteins associated with the axoneme of retinal photoreceptors
44. KIF3A is a new microtubule-based anterograde motor in the nerve axon
45. Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors
46. Actin filaments and photoreceptor membrane turnover
47. The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA gene
48. Human Usher 1B/mouse shaker-1: The retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells
49. Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells
50. A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3)
51. The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors
52. At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: A possible link between nuclear splicing and cytoplasmic translation