Invariant NKT cells promote alcohol-induced steatohepatitis through interleukin-1β in mice

Journal of Hepatology

Volumn 62, Issue 6, 2015, Pages 1311-1318

  Cui, Kele ^a   Yan, Guoxiu ^a   Xu, Congfei ^b   Chen, Yongyan ^a   Wang, Jun ^a,b   Zhou, Rongbin ^a   Bai, Li ^a   Lian, Zhexiong ^a   Wei, Haiming ^a,b   Sun, Rui ^a,b   Tian, Zhigang ^a,b,c  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Alcoholic steatohepatitis; IL 1 ; Kupffer cells; NKT cells

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; CLODRONIC ACID; CRYOPYRIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ETANERCEPT; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LIPOSOME; MESSENGER RNA; SMALL INTERFERING RNA; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOLIC FATTY LIVER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; DISEASE SEVERITY; HEPATITIS; HYDRODYNAMICS; IN VITRO STUDY; KUPFFER CELL; LIVER CELL; LYMPHOCYTE COUNT; MACROPHAGE; MALE; MOUSE; NANOENCAPSULATION; NATURAL KILLER T CELL; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DISEASE MODEL; FATTY LIVER, ALCOHOLIC; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; CASPASE 1; DISEASE MODELS, ANIMAL; FATTY LIVER, ALCOHOLIC; INFLAMMASOMES; INTERLEUKIN-1BETA; KUPFFER CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NATURAL KILLER T-CELLS; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84929606098     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.12.027     Document Type: Article

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