The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications

Expert Opinion on Therapeutic Targets

Volumn 19, Issue 6, 2015, Pages 849-864

  Qi Nan, Wu ^a   Ling, Zhang ^a   Bing, Chen ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Diabetes mellitus; Diabetic vascular complication; Oxidative stress; Telomere telomerase system

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 2; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; VASCULOTROPIN;

ADIPOSE DERIVED STEM CELL; AGE; APOPTOSIS; ATHEROSCLEROSIS; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CARDIOVASCULAR DISEASE; CELL AGING; CELL DIFFERENTIATION; CELL PROLIFERATION; DIABETIC HEART DYSFUNCTION; DIABETIC NEPHROPATHY; DIABETIC RETINOPATHY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEART DISEASE; HUMAN; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTENSION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PERIPHERAL BLOOD STEM CELL; REVIEW; SOMATIC CELL; STEM CELL TRANSPLANTATION; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; DIABETES MELLITUS; DIABETIC ANGIOPATHIES; DISEASE COURSE; GENE THERAPY; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES;

ANIMALS; DIABETES MELLITUS; DIABETIC ANGIOPATHIES; DISEASE PROGRESSION; DNA DAMAGE; GENETIC THERAPY; HUMANS; MOLECULAR TARGETED THERAPY; TELOMERASE; TELOMERE; TELOMERE HOMEOSTASIS;

EID: 84929603267     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2015.1016500     Document Type: Review

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