Structure, functional characterization, and evolution of the dihydroorotase domain of human CAD

Structure

Volumn 22, Issue 2, 2014, Pages 185-198

  Grande García, Araceli ^a   Lallous, Nada ^a,b   Díaz Tejada, Celsa ^a   Ramón Maiques, Santiago ^a  

^a Centro Nacional de Investigaciones Oncológicas   (Spain)

^b VANCOUVER PROSTATE CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE ACTIVATED DEOXYRIBONUCLEASE; DIHYDROOROTASE; ZINC ION; FLUOROOROTIC ACID; LYSINE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SITE DIRECTED MUTAGENESIS; AQUIFEX AEOLICUS; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVE SITE; NONHUMAN;

ANIMALIA; BACTERIA (MICROORGANISMS);

AMINO ACID SEQUENCE; ASPARTATE CARBAMOYLTRANSFERASE; BACTERIAL PROTEINS; CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING); CATALYSIS; CATALYTIC DOMAIN; CELL LINE; DIHYDROOROTASE; DNA REPAIR; ESCHERICHIA COLI; HEK293 CELLS; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; IONS; LYSINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEOPLASMS; PHOSPHORYLATION; PHYLOGENY; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

EID: 84893586146     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2013.10.016     Document Type: Article

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