Obstruction of adaptation in diploids by recessive, strongly deleterious alleles

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 20, 2015, Pages E2658-E2666

  Assaf, Zoe June ^a   Petrov, Dmitri A ^a   Blundell, Jamie R ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Adaptation; Hitchhiking; Inbreeding depression; Recessive; Selective sweep

Indexed keywords

ADAPTATION; ALLELE; ARTICLE; DIPLOIDY; DROSOPHILA MELANOGASTER; GENE FREQUENCY; GENE MUTATION; GENETIC VARIABILITY; GENOME; HETEROZYGOTE; HOMOZYGOTE; HUMAN; NATURAL POPULATION; NONHUMAN; PRIORITY JOURNAL; SELECTIVE SWEEP; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETICS; MUTATION; POPULATION GENETICS; RECESSIVE GENE;

ADAPTATION, BIOLOGICAL; ALLELES; COMPUTER SIMULATION; DIPLOIDY; GENES, RECESSIVE; GENETICS, POPULATION; MODELS, GENETIC; MUTATION;

EID: 84929578388     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424949112     Document Type: Article

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