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Volumn 148, Issue 3, 1998, Pages 1143-1158

Mutant alleles of small effect are primarily responsible for the loss of fitness with slow inbreeding in Drosophila melanogaster

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; AUTOSOME; DROSOPHILA MELANOGASTER; GENE LOCUS; GENE MUTATION; GENE SEGREGATION; GENETIC MODEL; HETEROZYGOTE; HOMOZYGOTE; INBREEDING; NONHUMAN; PRIORITY JOURNAL;

EID: 0031981501     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (36)

References (40)
  • 1
    • 0027043864 scopus 로고
    • Loss of genetic variation in large laboratory populations of Drosophila flies: Implications for the genetic management of captive populations
    • BRISCOE, D. A., J. M. MALPICA, A. ROBERTSON, G. J. SMITH, R. FRANKHAM et al., 1992 Loss of genetic variation in large laboratory populations of Drosophila flies: implications for the genetic management of captive populations. Conserv. Biol. 6: 416-425.
    • (1992) Conserv. Biol. , vol.6 , pp. 416-425
    • Briscoe, D.A.1    Malpica, J.M.2    Robertson, A.3    Smith, G.J.4    Frankham, R.5
  • 2
    • 0025756157 scopus 로고
    • The apparent selection on neutral marker loci in partially inbreeding populations
    • CHARLESWORTH, D., 1991 The apparent selection on neutral marker loci in partially inbreeding populations. Genet. Res. 57: 159-175.
    • (1991) Genet. Res. , vol.57 , pp. 159-175
    • Charlesworth, D.1
  • 3
    • 0026514918 scopus 로고
    • The effect of linkage and population size on inbreeding depression due to mutational load
    • CHARLESWORTH, D., M. T. MORGAN and B. CHARLESWORTH, 1992 The effect of linkage and population size on inbreeding depression due to mutational load. Genet. Res. 59: 49-61.
    • (1992) Genet. Res. , vol.59 , pp. 49-61
    • Charlesworth, D.1    Morgan, M.T.2    Charlesworth, B.3
  • 4
    • 0027313002 scopus 로고
    • Mutation accumulation in finite outbreeding and inbreeding populations
    • CHARLESWORTH, D., M. T. MORGAN and B. CHARLESWORTH, 1993 Mutation accumulation in finite outbreeding and inbreeding populations. Genet. Res. 61: 39-56.
    • (1993) Genet. Res. , vol.61 , pp. 39-56
    • Charlesworth, D.1    Morgan, M.T.2    Charlesworth, B.3
  • 5
    • 0002160422 scopus 로고
    • Genetic loads and the cost of natural selection
    • edited by K. KOJIMA. Springer-Verlag, Berlin
    • CROW, J. F., 1970 Genetic loads and the cost of natural selection, pp. 128-177 in Mathematical Topics in Population Genetics, edited by K. KOJIMA. Springer-Verlag, Berlin.
    • (1970) Mathematical Topics in Population Genetics , pp. 128-177
    • Crow, J.F.1
  • 6
    • 0002995790 scopus 로고
    • Mutation, mean fitness, and genetic load
    • edited by D. FUTUYMA and J. ANTONOVICS. Oxford University Press, Oxford
    • CROW, J. F., 1973 Mutation, mean fitness, and genetic load, pp. 3-42 in Oxford Surveys in Evolutionary Biology, Vol. 9, edited by D. FUTUYMA and J. ANTONOVICS. Oxford University Press, Oxford.
    • (1973) Oxford Surveys in Evolutionary Biology , vol.9 , pp. 3-42
    • Crow, J.F.1
  • 8
    • 0029559652 scopus 로고
    • Conservation genetics
    • FRANKHAM, R., 1995 Conservation genetics. Annu. Rev. Genet. 29: 305-327.
    • (1995) Annu. Rev. Genet. , vol.29 , pp. 305-327
    • Frankham, R.1
  • 9
    • 0039962816 scopus 로고
    • An analysis of temporal variation at isozyme loci in Drosophila melanogaster
    • edited by J. B. GIBSON and J. G. OAKESHOTT. Australian National University Press, Canberra
    • FRANKLIN, I. R., 1981 An analysis of temporal variation at isozyme loci in Drosophila melanogaster, pp. 217-236 in Genetic Studies of Drosophila Populations, edited by J. B. GIBSON and J. G. OAKESHOTT. Australian National University Press, Canberra.
    • (1981) Genetic Studies of Drosophila Populations , pp. 217-236
    • Franklin, I.R.1
  • 13
    • 0014357408 scopus 로고
    • The effects of inbreeding at loci with heterozygote advantage
    • HILL, W. G., and A. ROBERLSON, 1968 The effects of inbreeding at loci with heterozygote advantage. Genetics 60: 615-628.
    • (1968) Genetics , vol.60 , pp. 615-628
    • Hill, W.G.1    Roberlson, A.2
  • 15
    • 0028072361 scopus 로고
    • The distribution of mutation effects on viability in Drosophila melanogaster
    • KEIGHTLEY, P. D., 1994 The distribution of mutation effects on viability in Drosophila melanogaster. Genetics 138: 1315-1322.
    • (1994) Genetics , vol.138 , pp. 1315-1322
    • Keightley, P.D.1
  • 16
    • 0019732613 scopus 로고
    • Null allele frequencies at allozyme loci in natural populations of Drosophila melanogaster
    • LANGLEY, C. H., R. A. VOELKER, A. J. LEIGH BROWN, S. OHNISHI, B. DICKSON et al., 1981 Null allele frequencies at allozyme loci in natural populations of Drosophila melanogaster, Genetics 99: 151-156.
    • (1981) Genetics , vol.99 , pp. 151-156
    • Langley, C.H.1    Voelker, R.A.2    Leigh Brown, A.J.3    Ohnishi, S.4    Dickson, B.5
  • 17
    • 15444346288 scopus 로고
    • Models of quantitative genetic variation and computer simulation of selection response
    • edited by N. E. MORTON. University of Hawaii Press, Honolulu
    • LATTER, B. D. H., 1969 Models of quantitative genetic variation and computer simulation of selection response, pp. 49-60 in Computer Applications in Genetics, edited by N. E. MORTON. University of Hawaii Press, Honolulu.
    • (1969) Computer Applications in Genetics , pp. 49-60
    • Latter, B.D.H.1
  • 18
    • 0014846171 scopus 로고
    • Selection in finite populations with multiple alleles. II. Centripetal selection, mutation and isoallelic variation
    • LATTER, B. D. H., 1970 Selection in finite populations with multiple alleles. II. Centripetal selection, mutation and isoallelic variation. Genetics 66: 165-186.
    • (1970) Genetics , vol.66 , pp. 165-186
    • Latter, B.D.H.1
  • 19
    • 0015310208 scopus 로고
    • Selection in finite populations with multiple alleles. III. Genetic divergence with centripetal selection and mutation
    • LATTER, B. D. H., 1972 Selection in finite populations with multiple alleles. III. Genetic divergence with centripetal selection and mutation. Genetics 70: 475-490.
    • (1972) Genetics , vol.70 , pp. 475-490
    • Latter, B.D.H.1
  • 20
    • 0019731247 scopus 로고
    • The distribution of heterozygosity in temperate and tropical species of Drosophila
    • LATTER, B. D. H., 1981 The distribution of heterozygosity in temperate and tropical species of Drosophila. Genet. Res. 38: 137-156.
    • (1981) Genet. Res. , vol.38 , pp. 137-156
    • Latter, B.D.H.1
  • 21
    • 0028847817 scopus 로고
    • Genetic adaptation to captivity and inbreeding depression in small laboratory populations of Drosophila melanogaster
    • LATTER, B. D. H., and J. C. MULLEY, 1995 Genetic adaptation to captivity and inbreeding depression in small laboratory populations of Drosophila melanogaster. Genetics 139: 255-266.
    • (1995) Genetics , vol.139 , pp. 255-266
    • Latter, B.D.H.1    Mulley, J.C.2
  • 22
    • 0028872549 scopus 로고
    • Reduced genetic load revealed by slow inbreeding in Drosophila melanogaster
    • LATTER, B. D. H., J. C. MULLEY, D. REID and L. PASCOE, 1995 Reduced genetic load revealed by slow inbreeding in Drosophila melanogaster. Genetics 139: 197-207.
    • (1995) Genetics , vol.139 , pp. 197-207
    • Latter, B.D.H.1    Mulley, J.C.2    Reid, D.3    Pascoe, L.4
  • 23
    • 15444361136 scopus 로고
    • Selection in finite populations with multiple alleles. I. Limits to directional selection
    • LATTER, B. D. H., and C. E. NOVTTSKI, 1969 Selection in finite populations with multiple alleles. I. Limits to directional selection. Genetics 62: 859-876.
    • (1969) Genetics , vol.62 , pp. 859-876
    • Latter, B.D.H.1    Novttski, C.E.2
  • 24
    • 84974186380 scopus 로고
    • The effects of inbreeding and artificial selection on reproductive fitness
    • LATTER, B. D. H., and A. ROBERTSON, 1962 The effects of inbreeding and artificial selection on reproductive fitness. Genet. Res. 3: 110-138.
    • (1962) Genet. Res. , vol.3 , pp. 110-138
    • Latter, B.D.H.1    Robertson, A.2
  • 25
    • 0028360857 scopus 로고
    • A reevaluation of data from competitive tests shows high levels of heterosis in Drosophila melanogaster
    • LATTER, B. D. H., and J. A. SVED, 1994 A reevaluation of data from competitive tests shows high levels of heterosis in Drosophila melanogaster. Genetics 137: 509-511.
    • (1994) Genetics , vol.137 , pp. 509-511
    • Latter, B.D.H.1    Sved, J.A.2
  • 26
    • 0000434403 scopus 로고
    • Pleiotropism and the genetic variance and covariance
    • MODF, C. J., and H. F. ROBINSON, 1959 Pleiotropism and the genetic variance and covariance. Biometrics 15: 518-537.
    • (1959) Biometrics , vol.15 , pp. 518-537
    • Modf, C.J.1    Robinson, H.F.2
  • 27
    • 15444340993 scopus 로고    scopus 로고
    • Allozyme variation in finite populations of Drosophila melanogaster behaves as predicted by neutral theory
    • in press
    • MONTGOMERY, M. E., L. M. WOODWORTH, R. K. NURTHEN, D. A. BRISCOE and R. FRANKHAM, 1997 Allozyme variation in finite populations of Drosophila melanogaster behaves as predicted by neutral theory. Genel. Res. (in press).
    • (1997) Genel. Res.
    • Montgomery, M.E.1    Woodworth, L.M.2    Nurthen, R.K.3    Briscoe, D.A.4    Frankham, R.5
  • 28
    • 78651159254 scopus 로고
    • The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability
    • MUKAI, T., 1964 The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability. Genetics 50: 1-19.
    • (1964) Genetics , vol.50 , pp. 1-19
    • Mukai, T.1
  • 29
    • 15444349823 scopus 로고
    • Spontaneous mutation rates of isozyme genes in Drosophila melanogaster
    • MUKAI, T., 1970 Spontaneous mutation rates of isozyme genes in Drosophila melanogaster. Dros. Inform. Serv. 45: 99.
    • (1970) Dros. Inform. Serv. , vol.45 , pp. 99
    • Mukai, T.1
  • 30
    • 0008377728 scopus 로고
    • Spontaneous mutation rates of isozyme genes in Drosophila melanogaster
    • MUKAI, T., and C. C. COCKERHAM, 1977 Spontaneous mutation rates of isozyme genes in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 74: 2514-2517.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 2514-2517
    • Mukai, T.1    Cockerham, C.C.2
  • 31
    • 0015405272 scopus 로고
    • Mutation rate and dominance of genes affecting viability in Drosophila melanogaster
    • MUKAI, T., S. I. CHIGUSA, L. E. METTLER and J. F. GROW, 1972 Mutation rate and dominance of genes affecting viability in Drosophila melanogaster. Genetics 72: 335-355.
    • (1972) Genetics , vol.72 , pp. 335-355
    • Mukai, T.1    Chigusa, S.I.2    Mettler, L.E.3    Grow, J.F.4
  • 32
    • 0017717802 scopus 로고
    • Spontaneous and ethyl methanesulfonate-induced mutations controlling viability in Drosophila melanogaster. II. Homozygous effect of polygenic mutations
    • OHNLSHI, O., 1977 Spontaneous and ethyl methanesulfonate-induced mutations controlling viability in Drosophila melanogaster. II. Homozygous effect of polygenic mutations. Genetics 87: 547-556.
    • (1977) Genetics , vol.87 , pp. 547-556
    • Ohnlshi, O.1
  • 33
    • 0015177106 scopus 로고
    • Associative overdominance caused by linked detrimental mutations
    • OHTA, T., 1971 Associative overdominance caused by linked detrimental mutations. Genet. Res. 18: 277-286.
    • (1971) Genet. Res. , vol.18 , pp. 277-286
    • Ohta, T.1
  • 34
    • 0001519459 scopus 로고
    • Selection for heterozygotes in small populations
    • ROBERTSON, A., 1962 Selection for heterozygotes in small populations. Genetics 47: 1291-1300.
    • (1962) Genetics , vol.47 , pp. 1291-1300
    • Robertson, A.1
  • 35
    • 0028280289 scopus 로고
    • Decline in heterozygosity under full-sib and double firstcousin inbreeding in Drosophila. melanogaster
    • RUMBALL, W., I. R. FRANKLIN, R. FRANKHAM and B. L. SHELDON, 1994 Decline in heterozygosity under full-sib and double firstcousin inbreeding in Drosophila. melanogaster. Genetics 136: 1039-1049.
    • (1994) Genetics , vol.136 , pp. 1039-1049
    • Rumball, W.1    Franklin, I.R.2    Frankham, R.3    Sheldon, B.L.4
  • 36
    • 0014318183 scopus 로고
    • The stability of linked systems of loci with a small population size
    • SVED, J. A., 1968 The stability of linked systems of loci with a small population size. Genetics 59: 543-563.
    • (1968) Genetics , vol.59 , pp. 543-563
    • Sved, J.A.1
  • 37
    • 0015461719 scopus 로고
    • Heterosis at the level of the chromosome and at the level of the gene
    • SVED, J. A., 1972 Heterosis at the level of the chromosome and at the level of the gene. Theor. Popnl. Biol. 3: 491-506.
    • (1972) Theor. Popnl. Biol. , vol.3 , pp. 491-506
    • Sved, J.A.1
  • 38
    • 0342622171 scopus 로고
    • Inbreeding depression and the maintenance of deleterious genes by mutation: Model of a Drosophila chromosome
    • SVED, J. A., and A. N. WILTON, 1989 Inbreeding depression and the maintenance of deleterious genes by mutation: model of a Drosophila chromosome. Genet. Res. 53: 119-128.
    • (1989) Genet. Res. , vol.53 , pp. 119-128
    • Sved, J.A.1    Wilton, A.N.2
  • 39
    • 0015303913 scopus 로고
    • A study of spontaneous mutation rates at ten loci detectable by starch gel electrophoresis in Drosophila melanogaster
    • TOBARI,Y. N.,and K. KOJIMA, 1972 A study of spontaneous mutation rates at ten loci detectable by starch gel electrophoresis in Drosophila melanogaster. Genetics 70: 397-403.
    • (1972) Genetics , vol.70 , pp. 397-403
    • Tobari, Y.N.1    Kojima, K.2
  • 40
    • 0007101306 scopus 로고
    • Enzyme null alleles in natural populations of Drosophila melanogaster: Frequencies in a North Carolina population
    • VOKLER, R. A., C. H. LANGLEY, A. J. LEIGH BROWN, S. OHNISHI, B. DICKSON et al., 1980 Enzyme null alleles in natural populations of Drosophila melanogaster: frequencies in a North Carolina population. Proc. Natl. Acacl. Sci. USA 77: 1091-1095.
    • (1980) Proc. Natl. Acacl. Sci. USA , vol.77 , pp. 1091-1095
    • Vokler, R.A.1    Langley, C.H.2    Leigh Brown, A.J.3    Ohnishi, S.4    Dickson, B.5


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