메뉴 건너뛰기




Volumn 6, Issue 2, 2015, Pages

High-throughput analysis of gene essentiality and sporulation in Clostridium difficile

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL SPORE; BACTERIAL STRAIN; BACTERIUM MUTANT; CONTROLLED STUDY; ESSENTIAL GENE; GENE IDENTIFICATION; IN VITRO STUDY; MUTAGENESIS; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; PRIORITY JOURNAL; SPOROGENESIS; TRANSPOSON; GENE EXPRESSION REGULATION; GENETIC SCREENING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HIGH THROUGHPUT SCREENING; HUMAN; PROCEDURES;

EID: 84929494200     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.02383-14     Document Type: Article
Times cited : (126)

References (53)
  • 1
    • 67649391053 scopus 로고    scopus 로고
    • Clostridium difficile infection: New developments in epidemiology and pathogenesis
    • Rupnik M, Wilcox MH, Gerding DN. 2009. Clostridium difficile infection: new developments in epidemiology and pathogenesis. Nat Rev Microbiol 7:526–536. http://dx.doi.org/10.1038/nrmicro2164.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 526-536
    • Rupnik, M.1    Wilcox, M.H.2    Gerding, D.N.3
  • 2
    • 80053253206 scopus 로고    scopus 로고
    • Biology of Clostridium difficile: Implications for epidemiology and diagnosis
    • Carroll KC, Bartlett JG. 2011. Biology of Clostridium difficile: implications for epidemiology and diagnosis. Annu Rev Microbiol 65:501–521. http://dx.doi.org/10.1146/annurev-micro-090110-102824.
    • (2011) Annu Rev Microbiol , vol.65 , pp. 501-521
    • Carroll, K.C.1    Bartlett, J.G.2
  • 4
    • 84863694101 scopus 로고    scopus 로고
    • Burden of Clostridium difficile on the healthcare system
    • Dubberke ER, Olsen MA. 2012. Burden of Clostridium difficile on the healthcare system. Clin Infect Dis 55(Suppl 2):S88-S92. http://dx.doi.org/10.1093/cid/cis335.
    • (2012) Clin Infect Dis , vol.55 , pp. S88-S92
    • Dubberke, E.R.1    Olsen, M.A.2
  • 7
    • 39749111479 scopus 로고    scopus 로고
    • Measures to control and prevent Clostridium difficile infection
    • Gerding DN, Muto CA, Owens RC, Jr. 2008. Measures to control and prevent Clostridium difficile infection. Clin Infect Dis 46(Suppl 1): S43–S49. http://dx.doi.org/10.1086/521861.
    • (2008) Clin Infect Dis , vol.46 , pp. S43-S49
    • Gerding, D.N.1    Muto, C.A.2    Owens, R.C.3
  • 8
    • 30544443489 scopus 로고    scopus 로고
    • A comparative genomic view of clostridial sporulation and physiology
    • Paredes CJ, Alsaker KV, Papoutsakis ET. 2005. A comparative genomic view of clostridial sporulation and physiology. Nat Rev Microbiol 3:969–978. http://dx.doi.org/10.1038/nrmicro1288.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 969-978
    • Paredes, C.J.1    Alsaker, K.V.2    Papoutsakis, E.T.3
  • 9
    • 79959354609 scopus 로고    scopus 로고
    • The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile
    • Saujet L, Monot M, Dupuy B, Soutourina O, Martin-Verstraete I. 2011. The key sigma factor of transition phase, SigH, controls sporulation, metabolism, and virulence factor expression in Clostridium difficile. J Bacteriol 193:3186–3196. http://dx.doi.org/10.1128/JB.00272-11.
    • (2011) J Bacteriol , vol.193 , pp. 3186-3196
    • Saujet, L.1    Monot, M.2    Dupuy, B.3    Soutourina, O.4    Martin-Verstraete, I.5
  • 10
    • 71749105366 scopus 로고    scopus 로고
    • Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production
    • Underwood S, Guan S, Vijayasubhash V, Baines SD, Graham L, Lewis RJ, Wilcox MH, Stephenson K. 2009. Characterization of the sporulation initiation pathway of Clostridium difficile and its role in toxin production. J Bacteriol 191:7296–7305. http://dx.doi.org/10.1128/JB.00882-09.
    • (2009) J Bacteriol , vol.191 , pp. 7296-7305
    • Underwood, S.1    Guan, S.2    Vijayasubhash, V.3    Baines, S.D.4    Graham, L.5    Lewis, R.J.6    Wilcox, M.H.7    Stephenson, K.8
  • 14
    • 77956533047 scopus 로고    scopus 로고
    • Hierarchical evolution of the bacterial sporulation network
    • de Hoon MJ, Eichenberger P, Vitkup D. 2010. Hierarchical evolution of the bacterial sporulation network. Curr Biol 20:R735–R745. http://dx.doi.org/10.1016/j.cub.2010.06.031.
    • (2010) Curr Biol , vol.20 , pp. R735-R745
    • De Hoon, M.J.1    Eichenberger, P.2    Vitkup, D.3
  • 15
    • 14044268828 scopus 로고    scopus 로고
    • Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis
    • Steil L, Serrano M, Henriques AO, Völker U. 2005. Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis. Microbiology 151:399–420. http://dx.doi.org/10.1099/mic.0.27493-0.
    • (2005) Microbiology , vol.151 , pp. 399-420
    • Steil, L.1    Serrano, M.2    Henriques, A.O.3    Völker, U.4
  • 18
    • 84867988931 scopus 로고    scopus 로고
    • Genomic determinants of sporulation in Bacilli and Clostridia: Towards the minimal set of sporulation-specific genes
    • Galperin MY, Mekhedov SL, Puigbo P, Smirnov S, Wolf YI, Rigden DJ. 2012. Genomic determinants of sporulation in Bacilli and Clostridia: towards the minimal set of sporulation-specific genes. Environ Microbiol 14:2870–2890. http://dx.doi.org/10.1111/j.1462-2920.2012.02841.x.
    • (2012) Environ Microbiol , vol.14 , pp. 2870-2890
    • Galperin, M.Y.1    Mekhedov, S.L.2    Puigbo, P.3    Smirnov, S.4    Wolf, Y.I.5    Rigden, D.J.6
  • 20
    • 84873529552 scopus 로고    scopus 로고
    • Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: Allelic exchange using pyrE alleles
    • Ng YK, Ehsaan M, Philip S, Collery MM, Janoir C, Collignon A, Cartman ST, Minton NP. 2013. Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles. PLoS One 8:e56051. http://dx.doi.org/10.1371/journal.pone.0056051.
    • (2013) Plos One , vol.8
    • Ng, Y.K.1    Ehsaan, M.2    Philip, S.3    Collery, M.M.4    Janoir, C.5    Collignon, A.6    Cartman, S.T.7    Minton, N.P.8
  • 21
    • 84863792386 scopus 로고    scopus 로고
    • Precise manipulation of the Clostridium difficile chromosome reveals a lack of association between the tcdC genotype and toxin production
    • Cartman ST, Kelly ML, Heeg D, Heap JT, Minton NP. 2012. Precise manipulation of the Clostridium difficile chromosome reveals a lack of association between the tcdC genotype and toxin production. Appl Environ Microbiol 78:4683–4690. http://dx.doi.org/10.1128/AEM.00249-12.
    • (2012) Appl Environ Microbiol , vol.78 , pp. 4683-4690
    • Cartman, S.T.1    Kelly, M.L.2    Heeg, D.3    Heap, J.T.4    Minton, N.P.5
  • 22
    • 84880647378 scopus 로고    scopus 로고
    • Improved bacterial mutagenesis by highfrequency allele exchange, demonstrated in Clostridium difficile and Streptococcus suis
    • Faulds-Pain A, Wren BW. 2013. Improved bacterial mutagenesis by highfrequency allele exchange, demonstrated in Clostridium difficile and Streptococcus suis. Appl Environ Microbiol 79:4768–4771. http://dx.doi.org/10.1128/AEM.01195-13.
    • (2013) Appl Environ Microbiol , vol.79 , pp. 4768-4771
    • Faulds-Pain, A.1    Wren, B.W.2
  • 24
    • 84880876168 scopus 로고    scopus 로고
    • Approaches to querying bacterial genomes with transposon-insertion sequencing
    • Barquist L, Boinett CJ, Cain AK. 2013. Approaches to querying bacterial genomes with transposon-insertion sequencing. RNA Biol 10:1161–1169. http://dx.doi.org/10.4161/rna.24765.
    • (2013) RNA Biol , vol.10 , pp. 1161-1169
    • Barquist, L.1    Boinett, C.J.2    Cain, A.K.3
  • 25
    • 84879413726 scopus 로고    scopus 로고
    • Transposon insertion sequencing: A new tool for systems-level analysis of microorganisms
    • van Opijnen T, Camilli A. 2013. Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms. Nat Rev Microbiol 11: 435–442. http://dx.doi.org/10.1038/nrmicro3033.
    • (2013) Nat Rev Microbiol , vol.11 , pp. 435-442
    • Van Opijnen, T.1    Camilli, A.2
  • 26
    • 0031833703 scopus 로고    scopus 로고
    • Factors affecting transposition of the Himar1 mariner transposon in vitro
    • Lampe DJ, Grant TE, Robertson HM. 1998. Factors affecting transposition of the Himar1 mariner transposon in vitro. Genetics 149:179–187.
    • (1998) Genetics , vol.149 , pp. 179-187
    • Lampe, D.J.1    Grant, T.E.2    Robertson, H.M.3
  • 27
    • 76649121515 scopus 로고    scopus 로고
    • A mariner-based transposon system for in vivo random mutagenesis of Clostridium difficile
    • Cartman ST, Minton NP. 2010. A mariner-based transposon system for in vivo random mutagenesis of Clostridium difficile. Appl Environ Microbiol 76:1103–1109. http://dx.doi.org/10.1128/AEM.02525-09.
    • (2010) Appl Environ Microbiol , vol.76 , pp. 1103-1109
    • Cartman, S.T.1    Minton, N.P.2
  • 29
    • 79961004324 scopus 로고    scopus 로고
    • Clostridium difficile has two parallel and essential Sec secretion systems
    • Fagan RP, Fairweather NF. 2011. Clostridium difficile has two parallel and essential Sec secretion systems. J Biol Chem 286:27483–27493. http://dx.doi.org/10.1074/jbc.M111.263889.
    • (2011) J Biol Chem , vol.286 , pp. 27483-27493
    • Fagan, R.P.1    Fairweather, N.F.2
  • 30
    • 0025143351 scopus 로고
    • Regulated expression of heterologous genes in Bacillus subtilis using the Tn10 encoded tet regulatory elements
    • Geissendörfer M, Hillen W. 1990. Regulated expression of heterologous genes in Bacillus subtilis using the Tn10 encoded tet regulatory elements. Appl Microbiol Biotechnol 33:657-663. http://dx.doi.org/10.1007/BF00604933.
    • (1990) Appl Microbiol Biotechnol , vol.33 , pp. 657-663
    • Geissendörfer, M.1    Hillen, W.2
  • 31
    • 0036430107 scopus 로고    scopus 로고
    • Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier
    • Purdy D, O’Keeffe TA, Elmore M, Herbert M, McLeod A, Bokori- Brown M, Ostrowski A, Minton NP. 2002. Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier. Mol Microbiol 46:439- 452. http://dx.doi.org/10.1046/j.1365-2958.2002.03134.x.
    • (2002) Mol Microbiol , vol.46 , pp. 439-452
    • Purdy, D.1    O’Keeffe, T.A.2    Elmore, M.3    Herbert, M.4    McLeod, A.5    Bokori-Brown, M.6    Ostrowski, A.7    Minton, N.P.8
  • 32
    • 0029818461 scopus 로고    scopus 로고
    • A purified mariner transposase is sufficient to mediate transposition in vitro
    • Lampe DJ, Churchill ME, Robertson HM. 1996. A purified mariner transposase is sufficient to mediate transposition in vitro. EMBO J 15: 5470–5479.
    • (1996) EMBO J , vol.15 , pp. 5470-5479
    • Lampe, D.J.1    Churchill, M.E.2    Robertson, H.M.3
  • 34
    • 0029564162 scopus 로고
    • Nucleotide sequence and regulation of a new putative cell wall hydrolase gene, cwlD, which affects germination in Bacillus subtilis
    • Sekiguchi J, Akeo K, Yamamoto H, Khasanov FK, Alonso JC, Kuroda A. 1995. Nucleotide sequence and regulation of a new putative cell wall hydrolase gene, cwlD, which affects germination in Bacillus subtilis. J Bacteriol 177:5582–5589.
    • (1995) J Bacteriol , vol.177 , pp. 5582-5589
    • Sekiguchi, J.1    Akeo, K.2    Yamamoto, H.3    Khasanov, F.K.4    Alonso, J.C.5    Kuroda, A.6
  • 35
    • 68249127846 scopus 로고    scopus 로고
    • Novel secretion apparatus maintains spore integrity and developmental gene expression in Bacillus subtilis
    • Doan T, Morlot C, Meisner J, Serrano M, Henriques AO, Moran CP, Jr, Rudner DZ. 2009. Novel secretion apparatus maintains spore integrity and developmental gene expression in Bacillus subtilis. PLoS Genet 5:e1000566. http://dx.doi.org/10.1371/journal.pgen.1000566.
    • (2009) Plos Genet , vol.5
    • Doan, T.1    Morlot, C.2    Meisner, J.3    Serrano, M.4    Henriques, A.O.5    Moran, C.P.6    Rudner, D.Z.7
  • 36
    • 0034608820 scopus 로고    scopus 로고
    • The transcriptional profile of early to middle sporulation in Bacillus subtilis
    • Fawcett P, Eichenberger P, Losick R, Youngman P. 2000. The transcriptional profile of early to middle sporulation in Bacillus subtilis. Proc Natl Acad SciUSA 97:8063–8068. http://dx.doi.org/10.1073/pnas.140209597.
    • (2000) Proc Natl Acad Sciusa , vol.97 , pp. 8063-8068
    • Fawcett, P.1    Eichenberger, P.2    Losick, R.3    Youngman, P.4
  • 37
    • 84874693324 scopus 로고    scopus 로고
    • SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins
    • Putnam EE, Nock AM, Lawley TD, Shen A. 2013. SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins. J Bacteriol 195: 1214–1225. http://dx.doi.org/10.1128/JB.02181-12.
    • (2013) J Bacteriol , vol.195 , pp. 1214-1225
    • Putnam, E.E.1    Nock, A.M.2    Lawley, T.D.3    Shen, A.4
  • 40
    • 84920653323 scopus 로고    scopus 로고
    • SpoIIID-mediated regulation of sigma function during Clostridium difficile sporulation
    • Pishdadian K, Fimlaid KA, Shen A. 2015. SpoIIID-mediated regulation of sigma function during Clostridium difficile sporulation. Mol Microbiol 95:189–208. http://dx.doi.org/10.1111/mmi.12856.
    • (2015) Mol Microbiol , vol.95 , pp. 189-208
    • Pishdadian, K.1    Fimlaid, K.A.2    Shen, A.3
  • 42
    • 75149112859 scopus 로고    scopus 로고
    • SleC is essential for germination of Clostridium difficile spores in nutrient-rich medium supplemented with the bile salt taurocholate
    • Burns DA, Heap JT, Minton NP. 2010. SleC is essential for germination of Clostridium difficile spores in nutrient-rich medium supplemented with the bile salt taurocholate. J Bacteriol 192:657-664. http://dx.doi.org/10.1128/JB.01209-09.
    • (2010) J Bacteriol , vol.192 , pp. 657-664
    • Burns, D.A.1    Heap, J.T.2    Minton, N.P.3
  • 45
    • 83355169571 scopus 로고    scopus 로고
    • Recent progress in Bacillus subtilis sporulation
    • Higgins D, Dworkin J. 2012. Recent progress in Bacillus subtilis sporulation. FEMS Microbiol Rev 36:131–148. http://dx.doi.org/10.1111/j.1574-6976.2011.00310.x.
    • (2012) FEMS Microbiol Rev , vol.36 , pp. 131-148
    • Higgins, D.1    Dworkin, J.2
  • 47
    • 84863661973 scopus 로고    scopus 로고
    • Relapse versus reinfection: Recurrent Clostridium difficile infection following treatment with fidaxomicin or vancomycin
    • Figueroa I, Johnson S, Sambol SP, Goldstein EJ, Citron DM, Gerding DN. 2012. Relapse versus reinfection: recurrent Clostridium difficile infection following treatment with fidaxomicin or vancomycin. Clin Infect Dis 55(Suppl 2):S104-S109. http://dx.doi.org/10.1093/cid/cis357.
    • (2012) Clin Infect Dis , vol.55 , pp. S104-S109
    • Figueroa, I.1    Johnson, S.2    Sambol, S.P.3    Goldstein, E.J.4    Citron, D.M.5    Gerding, D.N.6
  • 48
    • 0031973385 scopus 로고    scopus 로고
    • Regulated transcription of Clostridium difficile toxin genes
    • Dupuy B, Sonenshein AL. 1998. Regulated transcription of Clostridium difficile toxin genes. Mol Microbiol 27:107–120. http://dx.doi.org/10.1046/j.1365-2958.1998.00663.x.
    • (1998) Mol Microbiol , vol.27 , pp. 107-120
    • Dupuy, B.1    Sonenshein, A.L.2
  • 49
    • 79959449569 scopus 로고    scopus 로고
    • Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B
    • Permpoonpattana P, Hong HA, Phetcharaburanin J, Huang JM, Cook J, Fairweather NF, Cutting SM. 2011. Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B. Infect Immun 79: 2295–2302. http://dx.doi.org/10.1128/IAI.00130-11.
    • (2011) Infect Immun , vol.79 , pp. 2295-2302
    • Permpoonpattana, P.1    Hong, H.A.2    Phetcharaburanin, J.3    Huang, J.M.4    Cook, J.5    Fairweather, N.F.6    Cutting, S.M.7
  • 50
    • 84877765660 scopus 로고    scopus 로고
    • Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores
    • Dembek M, Stabler RA, Witney AA, Wren BW, Fairweather NF. 2013. Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores. PLoS One 8:e64011. http://dx.doi.org/10.1371/journal.pone.0064011.
    • (2013) Plos One , vol.8
    • Dembek, M.1    Stabler, R.A.2    Witney, A.A.3    Wren, B.W.4    Fairweather, N.F.5
  • 51
    • 84891760956 scopus 로고    scopus 로고
    • Data, information, knowledge and principle: Back to metabolism in KEGG
    • Kanehisa M, Goto S, Sato Y, Kawashima M, Furumichi M, Tanabe M. 2014. Data, information, knowledge and principle: back to metabolism in KEGG. Nucleic Acids Res 42:D199–D205. http://dx.doi.org/10.1093/nar/gkt1076.
    • (2014) Nucleic Acids Res , vol.42 , pp. D199-D205
    • Kanehisa, M.1    Goto, S.2    Sato, Y.3    Kawashima, M.4    Furumichi, M.5    Tanabe, M.6
  • 52
    • 75249087100 scopus 로고    scopus 로고
    • EdgeR: A Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson MD, McCarthy DJ, Smyth GK. 2010. EdgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics 26:139-140. http://dx.doi.org/10.1093/bioinformatics/btp616.
    • (2010) Bioinformatics , vol.26 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.