Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development

mBio

Volumn 5, Issue 1, 2014, Pages

  Moule, Madeleine G ^a   Hemsley, Claudia M ^b   Seet, Qihui ^c   Guerra Assunção, José Afonso ^a   Lim, Jiali ^a   Sarkar Tyson, Mitali ^d   Clark, Taane G ^a   Tan, Patrick B O ^c   Titball, Richard W ^b   Cuccui, Jon ^a   Wren, Brendan W ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

^c GENOME INSTITUTE OF SINGAPORE   (Singapore)

^d DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIINFECTIVE AGENT; KANAMYCIN; PHLEOMYCIN;

ACCA GENE; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIUM MUTANT; BPSS0370 GENE; BURKHOLDERIA PSEUDOMALLEI; CONTROLLED STUDY; DRUG SYNTHESIS; DRUG TARGETING; ESSENTIAL GENE; GENE IDENTIFICATION; GENE INSERTION; GENE LIBRARY; GENE SEQUENCE; GENE TARGETING; GENOME ANALYSIS; LETHAL GENE; MUTAGENESIS; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PYRH GENE; SODB GENE; TRANSPOSON; VALIDATION STUDY;

BURKHOLDERIA PSEUDOMALLEI; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; GENES, BACTERIAL; GENES, ESSENTIAL; GENOME, BACTERIAL; MUTAGENESIS, INSERTIONAL; SEQUENCE ANALYSIS, DNA;

EID: 84903364041     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00926-13     Document Type: Article

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