The entropic contributions in vitamin B12 enzymes still reflect the electrostatic paradigm

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 14, 2015, Pages 4328-4333

  Schopf, Patrick ^a   Mills, Matthew J L ^b,c   Warshel, Arieh ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b JOINT BIOENERGY INSTITUTE   (United States)

^c SANDIA NATIONAL LABORATORIES   (United States)

Author keywords

Entropy calculations; EVB; Free energy methods; Vitamin B12 catalysis

Indexed keywords

COBAMAMIDE; CYANOCOBALAMIN; METHYLMALONYL COENZYME A MUTASE; HYDROGEN;

ARTICLE; CATALYSIS; DIPOLE; ELECTRIC FIELD; ENERGY TRANSFER; ENTHALPY; ENTROPY; ENZYME ACTIVE SITE; LOW TEMPERATURE; MOLECULAR MECHANICS; PRIORITY JOURNAL; QUANTUM MECHANICS; ROOM TEMPERATURE; STATIC ELECTRICITY; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; PROCEDURES; PROTEIN DATABASE; QUANTUM THEORY; THERMODYNAMICS;

CATALYSIS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DATABASES, PROTEIN; ENTROPY; HYDROGEN; METHYLMALONYL-COA MUTASE; MODELS, MOLECULAR; QUANTUM THEORY; STATIC ELECTRICITY; THERMODYNAMICS; VITAMIN B 12;

EID: 84929493073     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1503828112     Document Type: Article

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