Computational insights into the mechanism of radical generation in B 12-dependent methylmalonyl-CoA mutase

Journal of the American Chemical Society

Volumn 128, Issue 4, 2006, Pages 1287-1292

  Kwiecien, Renata A ^a   Khavrutskii, Ilja V ^b,d   Musaev, Djamaladdin G ^b   Morokuma, Keiji ^b   Banerjee, Ruma ^c   Paneth, Piotr ^a  

^a LODZ UNIVERSITY OF TECHNOLOGY   (Poland)

^b EMORY UNIVERSITY   (United States)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPUTATION THEORY; CONFORMATIONS; ENZYMES; HYDROGEN; SUBSTRATES;

COMPUTATIONAL INSIGHTS; CONFORMATIONAL CHANGES; METHYLMALONYL-COA MUTASE; RADICAL PRODUCTS;

ENZYME KINETICS;

COBAMAMIDE; CYANOCOBALAMIN; DEOXYADENOSINE DERIVATIVE; METHYLMALONYL COENZYME A MUTASE; RADICAL;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ENERGY; ENZYME ACTIVITY; ENZYME SUBSTRATE; GEOMETRY; HYDROGEN BOND; MOLECULAR MODEL; QUANTUM MECHANICS;

ADENOSINE; BINDING SITES; COBAMIDES; HYDROGEN BONDING; METHYLMALONYL-COA MUTASE; MODELS, MOLECULAR; PROTEIN CONFORMATION; THERMODYNAMICS;

EID: 31944447510     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja056333j     Document Type: Article

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