Hantaan Virus Infection Induces Both Th1 and ThGranzyme B+ Cell Immune Responses That Associated with Viral Control and Clinical Outcome in Humans

PLoS Pathogens

Volumn 11, Issue 4, 2015, Pages

  Ma, Ying ^a   Yuan, Bin ^b   Zhuang, Ran ^a   Zhang, Yusi ^a   Liu, Bei ^a   Zhang, Chunmei ^a   Zhang, Yun ^a   Yu, Haitao ^c   Yi, Jing ^a   Yang, Angang ^a   Jin, Boquan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; CD38 ANTIGEN; CD45RA ANTIGEN; CD57 ANTIGEN; CHEMOKINE RECEPTOR CCR7; EPITOPE; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 7 RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PERFORIN; PROGRAMMED DEATH 1 LIGAND 1; TUMOR NECROSIS FACTOR ALPHA; VIRUS GLYCOPROTEIN; GLYCOPROTEIN; GRANZYME; VIRAL PROTEIN; VIRUS RNA;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION ASSAY; CELLULAR IMMUNITY; CONTROLLED STUDY; CONVALESCENCE; CREATININE BLOOD LEVEL; CYTOKINE RELEASE; CYTOTOXICITY ASSAY; DEGRANULATION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEVER; FLOW CYTOMETRY; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMAN; IMMUNE RESPONSE; INFECTION CONTROL; MAJOR CLINICAL STUDY; MEMORY T LYMPHOCYTE; OLIGURIA; PEPTIDE SYNTHESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA VIRUS; TH1 CELL; UPREGULATION; VIREMIA; VIRUS LOAD; ADULT; FEMALE; HANTAAN VIRUS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; VIROLOGY;

HANTAAN VIRUS;

ADULT; CD8-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES, T-LYMPHOCYTE; FEMALE; FLOW CYTOMETRY; GLYCOPROTEINS; GRANZYMES; HANTAAN VIRUS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RNA, VIRAL; TH1 CELLS; VIRAL PROTEINS;

EID: 84929485966     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004788     Document Type: Article

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