Generation of an HFRS patient-derived neutralizing recombinant antibody to Hantaan virus G1 protein and definition of the neutralizing domain

Journal of Medical Virology

Volumn 69, Issue 1, 2003, Pages 99-107

  Liang, Mifang ^a   Mahler, Michael ^b   Koch, Joachim ^c   Ji, Yan ^a   Li, Dexin ^a   Schmaljohn, Connie ^d   Bautz, Ekkehard K F ^b,c  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HEIDELBERG ACADEMY OF SCIENCES AND HUMANITIES   (Germany)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Epitope mapping; G1 protein; Hantaan virus; Human recombinant antibody; Phage display

Indexed keywords

GLYCOPROTEIN G1; IMMUNOGLOBULIN F(AB) FRAGMENT; NEUTRALIZING ANTIBODY; NUCLEOCAPSID PROTEIN; THROMBOSPONDIN; UNCLASSIFIED DRUG; VIRUS ANTIBODY; VIRUS PROTEIN; VIRUS RNA;

AMINO ACID SEQUENCE; ARTICLE; BACULOVIRUS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EPITOPE MAPPING; HANTAVIRUS; HUMAN; HUMAN CELL; INSECT CELL; LYMPHOCYTE; MOLECULAR CLONING; NONHUMAN; SEOUL VIRUS; VIRUS HEMORRHAGIC FEVER; VIRUS PATHOGENESIS;

ANTIBODIES, VIRAL; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; HANTAAN VIRUS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; NEUTRALIZATION TESTS; NUCLEOCAPSID PROTEINS; NUCLEOPOLYHEDROVIRUS; PEPTIDE LIBRARY; RECOMBINANT PROTEINS;

BUNYAVIRIDAE; HANTAAN VIRUS; HANTAVIRUS; INSECTA; SEOUL VIRUS; UNIDENTIFIED BACULOVIRUS;

EID: 0037211471     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.10259     Document Type: Article

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