Inflammation enhances IL-2 driven differentiation of cytolytic CD4 T cells

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Workman, Aspen M ^a,b   Jacobs, Ashley K ^b   Vogel, Alexander J ^a   Condon, Shirley ^a,b   Brown, Deborah M ^a,b  

^a UNIVERSITY OF NEBRASKA   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EOMESODERMIN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR ALPHA; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; PERFORIN; STAT5 PROTEIN; GRANZYME; JANUS KINASE 3; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEGRANULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INFLUENZA A; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TH1 CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CYTOLOGY; CYTOTOXIC T LYMPHOCYTE; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANZYMES; INFLAMMATION; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; JANUS KINASE 3; MICE; MICE, INBRED BALB C; PERFORIN; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS;

EID: 84895878852     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089010     Document Type: Article

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