Thrombocytopenia as a Predictor of Severe Acute Kidney Injury in Patients with Hantaan Virus Infections

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Wang, Meiliang ^a   Wang, Jiuping ^b   Wang, Tianping ^b   Li, Jing ^b   Hui, Ling ^a,c   Ha, Xiaoqin ^a,c  

^a LANZHOU GENERAL HOSPITAL   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c Gansu Key Laboratory of Stem Cell and Gene Therapy   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CREATININE; NITROGEN; UREA;

ACUTE KIDNEY FAILURE; ACUTE PANCREATITIS; ADULT; AREA UNDER THE CURVE; ARTICLE; BRAIN DISEASE; BRAIN EDEMA; BRAIN HEMORRHAGE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEATH; DIAGNOSTIC ACCURACY; DIALYSIS; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE SEVERITY; FEMALE; HANTAVIRUS; HEMATURIA; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMAN; LENGTH OF STAY; LEUKOCYTE COUNT; LEUKOCYTOSIS; LUNG EDEMA; LUNG HEMORRHAGE; LUNG INFECTION; LUNG INSUFFICIENCY; MAJOR CLINICAL STUDY; MALE; MULTIPLE ORGAN FAILURE; PREVALENCE; PROGNOSIS; PROTEINURIA; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; RESPIRATORY DISTRESS; RETROSPECTIVE STUDY; RISK FACTOR; SHOCK; THROMBOCYTE COUNT; THROMBOCYTOPENIA; UREA NITROGEN BLOOD LEVEL; UREMIC ENCEPHALOPATHY;

ACUTE KIDNEY INJURY; ADULT; AREA UNDER CURVE; CREATININE; FEMALE; HANTAAN VIRUS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PLATELET COUNT; PREVALENCE; PROGNOSIS; RETROSPECTIVE STUDIES; THROMBOCYTOPENIA;

HANTAAN VIRUS;

EID: 84871809432     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053236     Document Type: Article

References (21)

1. Klein SL, Marks MA, Li W, Glass GE, Fang LQ, et al. (2011) Sex differences in the incidence and case fatality rates from hemorrhagic fever with renal syndrome in China, 2004-2008. Clin Infect Dis 52: 1414-1421.
2. Wang M, Wang J, Zhu Y, Xu Z, Yang K, et al. (2009) Cellular immune response to Hantaan virus nucleocapsid protein in the acute phase of hemorrhagic fever with renal syndrome: correlation with disease severity. J Infect Dis 199: 188-195.
3. Denecke B, Bigalke B, Haap M, Overkamp D, Lehnert H, et al. (2010) Hantavirus infection: a neglected diagnosis in thrombocytopenia and fever? Mayo Clin Proc 85: 1016-1020.
4. Rasche FM, Uhel B, Kruger DH, Karges W, Czock D, et al. (2004) Thrombocytopenia and acute renal failure in Puumala hantavirus infections. Emerg Infect Dis 10: 1420-1425.
5. Kim YO, Yoon SA, Ku YM, Yang CW, Kim YS, et al. (2003) Serum albumin level correlates with disease severity in patients with Hemorrhagic Fever with Renal Syndrome. J Korean Med Sci 18: 696-700.
6. Kim YK, Lee SC, Kim C, Heo ST, Choi C, et al. (2007) Clinical and laboratory predictors of oliguric renal failure in haemorrhagic fever with renal syndrome caused by Hantaan virus. J Infect 54: 381-386.
7. Takala A, Lahdevirta J, Jansson SE, Vapalahti O, Orpana A, et al. (2000) Systemic inflammation in hemorrhagic fever with renal syndrome correlates with hypotension and thrombocytopenia but not with renal injury. J Infect Dis 181: 1964-1970.
8. Outinen TK, Makela SM, Ala-Houhala IO, Huhtala HS, Hurme M, et al. (2010) The severity of Puumala hantavirus induced nephropathia epidemica can be better evaluated using plasma interleukin-6 than C-reactive protein determinations. BMC Infect Dis 10: 132.
9. Sane J, Laine O, Makela S, Paakkala A, Jarva H, et al. (2012) Complement activation in Puumala hantavirus infection correlates with disease severity. Ann Med 44: 468-475.
10. Libraty DH, Makela S, Vlk J, Hurme M, Vaheri A, et al. (2012) The Degree of Leukocytosis and Urine GATA-3 mRNA Levels Are Risk Factors for Severe Acute Kidney Injury in Puumala Virus Nephropathia Epidemica. PLoS One 7: e35402.
11. Geisbert TW, Jahrling PB, (2004) Exotic emerging viral diseases: progress and challenges. Nat Med 10: S110-121.
12. Pozner RG, Ure AE, Jaquenod de Giusti C, D'Atri LP, Italiano JE, et al. (2010) Junin virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling. PLoS Pathog 6: e1000847.
13. Laine O, Makela S, Mustonen J, Huhtala H, Szanto T, et al. (2010) Enhanced thrombin formation and fibrinolysis during acute Puumala hantavirus infection. Thromb Res 126: 154-158.
14. Onguru P, Dagdas S, Bodur H, Yilmaz M, Akinci E, et al. (2010) Coagulopathy parameters in patients with Crimean-Congo hemorrhagic fever and its relation with mortality. J Clin Lab Anal 24: 163-166.
15. Sundberg E, Hultdin J, Nilsson S, Ahlm C, (2011) Evidence of disseminated intravascular coagulation in a hemorrhagic fever with renal syndrome-scoring models and severe illness. PLoS One 6: e21134.
16. Balmaseda A, Hammond SN, Perez MA, Cuadra R, Solano S, et al. (2005) Assessment of the World Health Organization scheme for classification of dengue severity in Nicaragua. Am J Trop Med Hyg 73: 1059-1062.
17. Hammond SN, Balmaseda A, Perez L, Tellez Y, Saborio SI, et al. (2005) Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua. Am J Trop Med Hyg 73: 1063-1070.
18. Tanner L, Schreiber M, Low JG, Ong A, Tolfvenstam T, et al. (2008) Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness. PLoS Negl Trop Dis 2: e196.
19. Tasdelen Fisgin N, Tanyel E, Doganci L, Tulek N, (2009) Risk factors for fatality in patients with Crimean-Congo haemorrhagic fever. Trop Doct 39: 158-160.
20. Cevik MA, Erbay A, Bodur H, Gulderen E, Bastug A, et al. (2008) Clinical and laboratory features of Crimean-Congo hemorrhagic fever: predictors of fatality. Int J Infect Dis 12: 374-379.
21. Liu KD, Himmelfarb J, Paganini E, Ikizler TA, Soroko SH, et al. (2006) Timing of initiation of dialysis in critically ill patients with acute kidney injury. Clin J Am Soc Nephrol 1: 915-919.