Treatment with Trehalose Prevents Behavioral and Neurochemical Deficits Produced in an AAV α-Synuclein Rat Model of Parkinson’s Disease

Molecular Neurobiology

Volumn 53, Issue 4, 2016, Pages 2258-2268

  He, Qing ^a,c   Koprich, James B ^b   Wang, Ying ^a   Yu, Wen bo ^a   Xiao, Bao guo ^a   Brotchie, Jonathan M ^b   Wang, Jian ^a  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Autophagy; DA; Parkinson s disease; Trehalose; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; DOPAMINE; TREHALOSE; GLUCOSE BLOOD LEVEL; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN; TYROSINE 3 MONOOXYGENASE;

ADENO ASSOCIATED VIRUS 1; ADENO ASSOCIATED VIRUS 2; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; AUTOPHAGY; BEHAVIOR DISORDER; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; FEMALE; NEUROCHEMISTRY; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; STRIATONIGRAL DEGENERATION; ANIMAL; ANIMAL BEHAVIOR; BLOOD; BOVINE; DEPENDOPARVOVIRUS; DISEASE MODEL; DRUG EFFECTS; GLUCOSE BLOOD LEVEL; HUMAN; LIMB; METABOLISM; PATHOLOGY; SOLUBILITY; SPRAGUE DAWLEY RAT; SUBSTANTIA NIGRA;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; BEHAVIOR, ANIMAL; BLOOD GLUCOSE; CATTLE; CELL SURVIVAL; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; EXTREMITIES; FEMALE; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; PARKINSON DISEASE; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SUBSTANTIA NIGRA; TREHALOSE; TYROSINE 3-MONOOXYGENASE;

EID: 84929448327     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9173-7     Document Type: Article

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