-
1
-
-
84863279872
-
Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases
-
Xu, J. M.; Shi, G. P. Emerging role of mast cells and macrophages in cardiovascular and metabolic diseases. Endocr. Rev. 2012, 33, 71-108.
-
(2012)
Endocr. Rev
, vol.33
, pp. 71-108
-
-
Xu, J.M.1
Shi, G.P.2
-
2
-
-
44349161098
-
Alternative M2 activation of Kupffer cells by PPARδameliorates obesity-induced insulin resistance
-
Odegaard, J. I.; Ricardo-Gonzalez, R. R.; Red Eagle, A.; Vats, D.; Morel, C. R.; Gogorth, M. H.; Subramanian, V.; Mukundan, L.; Ferrante, A. W.; Chawla, A.; et al. Alternative M2 activation of Kupffer cells by PPARδameliorates obesity-induced insulin resistance. Cell Metab. 2008, 7, 496-507.
-
(2008)
Cell Metab
, vol.7
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red Eagle, A.3
Vats, D.4
Morel, C.R.5
Gogorth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
3
-
-
74149085153
-
Oxidative stress and glutathione in TGF-β-mediated fibrogenesis
-
Liu, R.-M.; Gaston Pravia, K. A. Oxidative stress and glutathione in TGF-β-mediated fibrogenesis. Free Radic. Biol. Med. 2010, 48, 1-15.
-
(2010)
Free Radic. Biol. Med
, vol.48
, pp. 1-15
-
-
Liu, R.-M.1
Gaston Pravia, K.A.2
-
4
-
-
84919460745
-
TH1/TH2 paradigm extended: Macrophage polarization as an unappreciated pathogen-driven escape mechanism
-
Muraille, E.; Leo, O.; Moser, M. TH1/TH2 paradigm extended: Macrophage polarization as an unappreciated pathogen-driven escape mechanism. Front. Immunol. 2014, 5, 603, doi: 10. 3389/fimmu. 2014. 00603.
-
(2014)
Front. Immunol
, vol.5
-
-
Muraille, E.1
Leo, O.2
Moser, M.3
-
5
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
Kumar, H.; Kawai, T.; Akira, S. Pathogen recognition by the innate immune system. Int. Rev. Immunol. 2011, 30, 16-34.
-
(2011)
Int. Rev. Immunol
, vol.30
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
6
-
-
84867799461
-
Toll-like receptor signaling pathways in cardiovascular disease: Challenges and opportunities
-
Moghimpour Bijani, F.; Vallejo, J. G.; Rezaei, N. Toll-like receptor signaling pathways in cardiovascular disease: Challenges and opportunities. Int. Rev. Immunol. 2012, 31, 379-395.
-
(2012)
Int. Rev. Immunol
, vol.31
, pp. 379-395
-
-
Moghimpour Bijani, F.1
Vallejo, J.G.2
Rezaei, N.3
-
7
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng, C. N.; Bodzin Saltiel, A. R. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Investig. 2007, 117, 175-184.
-
(2007)
J. Clin. Investig
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin Saltiel, A.R.2
-
8
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
Lee, J. Y.; Sohn, K. H.; Rhee, S. H.; Hwang, D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem. 2001, 276, 16683-16689.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
9
-
-
77954672503
-
Adipose tissue macrophages: Their role in adipose tissue remodeling
-
Suganami, T.; Ogawa, Y. Adipose tissue macrophages: Their role in adipose tissue remodeling. J. Leukoc. Biol. 2010, 88, 33-39.
-
(2010)
J. Leukoc. Biol
, vol.88
, pp. 33-39
-
-
Suganami, T.1
Ogawa, Y.2
-
10
-
-
84884167722
-
Octanoylated Ghrelin Inhibits the Activation of the Palmitic Acid-Induced TLR4/NF-κB Signaling Pathway in THP-1 Macrophages
-
Liu, S. P.; Li, X. Y.; Li, Z.; He, L. N.; Xiao, Y.; Yan, K.; Zhou, Z. G. Octanoylated Ghrelin Inhibits the Activation of the Palmitic Acid-Induced TLR4/NF-κB Signaling Pathway in THP-1 Macrophages. ISRN Endocrinol. 2012, 2012, 237613, doi: 10. 5402/2012/237613.
-
(2012)
ISRN Endocrinol
, vol.2012
-
-
Liu, S.P.1
Li, X.Y.2
Li, Z.3
He, L.N.4
Xiao, Y.5
Yan, K.6
Zhou, Z.G.7
-
11
-
-
34548272744
-
Toll-like receptor-4 signaling and Kupffer cells play privotal roles in the pathogenesis of non-alcoholic steatohepatitis
-
Rivera, C. A.; Adegboyega, P.; van Rooijen, N.; Tagalicud, A.; Allman, M.; Wallace, M. Toll-like receptor-4 signaling and Kupffer cells play privotal roles in the pathogenesis of non-alcoholic steatohepatitis. J. Hepatol. 2007, 47, 571-579.
-
(2007)
J. Hepatol
, vol.47
, pp. 571-579
-
-
Rivera, C.A.1
Adegboyega, P.2
van Rooijen, N.3
Tagalicud, A.4
Allman, M.5
Wallace, M.6
-
12
-
-
34547602916
-
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
-
Tsukumo, D. M.; Carvalho, M. A.; Carvalherira, J. B.; Prada, P. O.; Hirabara, S. M.; Schenka, A. A.; Araujo, E. P.; Vassallo, J.; Curi, R.; Velloso, L. A.; et al. Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 2007, 56, 1986-1998.
-
(2007)
Diabetes
, vol.56
, pp. 1986-1998
-
-
Tsukumo, D.M.1
Carvalho, M.A.2
Carvalherira, J.B.3
Prada, P.O.4
Hirabara, S.M.5
Schenka, A.A.6
Araujo, E.P.7
Vassallo, J.8
Curi, R.9
Velloso, L.A.10
-
13
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach, M.; Schwanhausser, B.; Thierfelder, N.; Fang, Z.; Khanin, R.; Rajewsky, N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008, 455, 58-63.
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
14
-
-
60149095444
-
Moat mammalian mRNAs are conserved targets of microRNAs
-
Friedman, R. C.; Farh, K. K.; Burge, C. B.; Bartel, D. P. Moat mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009, 19, 92-105.
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
15
-
-
84903778202
-
miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1and TRAF6
-
Jiang, W.; Kong, L.; Ni, Q.; Lu, Y.; Ding, W.; Liu, G.; Pu, L.; Tang, W.; Kong, L. miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1and TRAF6. PLoS ONE 2014, 2, e101530.
-
(2014)
PLoS ONE
, vol.2
-
-
Jiang, W.1
Kong, L.2
Ni, Q.3
Lu, Y.4
Ding, W.5
Liu, G.6
Pu, L.7
Tang, W.8
Kong, L.9
-
16
-
-
73349117487
-
Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome
-
Fessler, M. B.; Rudel, L. L.; Brown, J. M. Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome. Curr. Opin. Lipidol. 2009, 20, 379-385.
-
(2009)
Curr. Opin. Lipidol
, vol.20
, pp. 379-385
-
-
Fessler, M.B.1
Rudel, L.L.2
Brown, J.M.3
-
17
-
-
84882911145
-
Toll like receptor (TLR)-induced differential expression of microRNAs (MiRs) and immune response against infection: A systematic review
-
Aalaei-andabili, S. H.; Nima, R. Toll like receptor (TLR)-induced differential expression of microRNAs (MiRs) and immune response against infection: A systematic review. J. Infect. 2013, 67, 251-264.
-
(2013)
J. Infect
, vol.67
, pp. 251-264
-
-
Aalaei-Andabili, S.H.1
Nima, R.2
-
18
-
-
84860001601
-
miR-Sens-a retroviral dual-luciferase reporter to detect microRNA activity in primary cells
-
Beillard, E.; Ong, S. C.; Giannakakis, A.; Guccione, E.; Vardy, L. A.; Voorhoeve, P. M. miR-Sens-a retroviral dual-luciferase reporter to detect microRNA activity in primary cells. RNA 2012, 18, 1091-1100.
-
(2012)
RNA
, vol.18
, pp. 1091-1100
-
-
Beillard, E.1
Ong, S.C.2
Giannakakis, A.3
Guccione, E.4
Vardy, L.A.5
Voorhoeve, P.M.6
-
20
-
-
4644338458
-
Circulating monounuclear cells in the obese are in a proinflammatory state
-
Ghanim, H.; Aljada, A.; Hofmeyer, D.; Syed, T.; Mohanty, P.; Dandona, P. Circulating monounuclear cells in the obese are in a proinflammatory state. Circulation 2004, 110, 1564-1571.
-
(2004)
Circulation
, vol.110
, pp. 1564-1571
-
-
Ghanim, H.1
Aljada, A.2
Hofmeyer, D.3
Syed, T.4
Mohanty, P.5
Dandona, P.6
-
21
-
-
0348222671
-
Inflammation: The link between insulin resistance, obesity and diabetes
-
Dandona, P.; Aljiada, A.; Bandyopadhyay, A. Inflammation: The link between insulin resistance, obesity and diabetes. Trends Immunol. 2004, 25, 4-7.
-
(2004)
Trends Immunol
, vol.25
, pp. 4-7
-
-
Dandona, P.1
Aljiada, A.2
Bandyopadhyay, A.3
-
22
-
-
69949140723
-
Toll-like receptors and innate immunity
-
Kumar, H.; Kawai, T.; Akira, S. Toll-like receptors and innate immunity. Biochem. Biophys. Res. Commun. 2009, 388, 621-625.
-
(2009)
Biochem. Biophys. Res. Commun
, vol.388
, pp. 621-625
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
23
-
-
84862669638
-
Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis
-
Leroux, A.; Ferrere, G.; Godie, V.; Cailleux, F.; Renoud, M. L.; Gaudin, F.; Naveau, S.; Prevot, S.; Makhzami, S.; Perlemuter, G.; et al. Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis. J. Hepatol. 2012, 57, 141-149.
-
(2012)
J. Hepatol
, vol.57
, pp. 141-149
-
-
Leroux, A.1
Ferrere, G.2
Godie, V.3
Cailleux, F.4
Renoud, M.L.5
Gaudin, F.6
Naveau, S.7
Prevot, S.8
Makhzami, S.9
Perlemuter, G.10
-
24
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
Henao-Mejia, J.; Elinav, E.; Jin, C.; Hao, L.; Mehal, W. Z.; Strowig, T.; Thaiss, C. A.; Kau, A. L.; Eisenbarth, S. C.; Jurczak, M. J.; et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012, 482, 179-185.
-
(2012)
Nature
, vol.482
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
Hao, L.4
Mehal, W.Z.5
Strowig, T.6
Thaiss, C.A.7
Kau, A.L.8
Eisenbarth, S.C.9
Jurczak, M.J.10
-
25
-
-
79952230506
-
Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease
-
Miura, K.; Seki, E.; Ohnishi, H.; Brenner, D. A. Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. Gastroenterol. Res. Pract. 2010, 2010, 362847, doi: 10. 1155/2010/362847.
-
(2010)
Gastroenterol. Res. Pract
, vol.2010
-
-
Miura, K.1
Seki, E.2
Ohnishi, H.3
Brenner, D.A.4
-
26
-
-
84880425458
-
Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis
-
Roh, Y. S.; Seki, E. Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis. J. Gastroenterol. Hepatol. 2013, 28, 38-42.
-
(2013)
J. Gastroenterol. Hepatol
, vol.28
, pp. 38-42
-
-
Roh, Y.S.1
Seki, E.2
-
27
-
-
26244448904
-
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha
-
Suganami, T.; Nishida, J.; Ogawa, Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha. Arterioscler. Thromb. Vasc. Biol. 2005, 25, 2062-2068.
-
(2005)
Arterioscler. Thromb. Vasc. Biol
, vol.25
, pp. 2062-2068
-
-
Suganami, T.1
Nishida, J.2
Ogawa, Y.3
-
28
-
-
0033975141
-
Modulatory effects of dietary lipids on immune system function
-
De Pablo, M. A.; de Cienfuegos, G. A. Modulatory effects of dietary lipids on immune system function. Immunol. Cell Biol. 2000, 78, 31-39.
-
(2000)
Immunol. Cell Biol
, vol.78
, pp. 31-39
-
-
De Pablo, M.A.1
de Cienfuegos, G.A.2
-
29
-
-
84871284466
-
Toll-like receptor 4 signaling augments transforming growth factor-β responses: A novel mechanism for maintaining and amplifying fibrosis in scleroderma
-
Bhattacharyya, S.; Kelley, K.; Melichian, D. S.; Tamaki, Z.; Fang, F.; Su, Y.; Feng, G.; Pope, R. M.; Budinger, G. R.; Mutlu, G. M.; et al. Toll-like receptor 4 signaling augments transforming growth factor-β responses: A novel mechanism for maintaining and amplifying fibrosis in scleroderma. Am. J. Pathol. 2013, 182, 192-205.
-
(2013)
Am. J. Pathol
, vol.182
, pp. 192-205
-
-
Bhattacharyya, S.1
Kelley, K.2
Melichian, D.S.3
Tamaki, Z.4
Fang, F.5
Su, Y.6
Feng, G.7
Pope, R.M.8
Budinger, G.R.9
Mutlu, G.M.10
-
30
-
-
67349205002
-
Kupffer cells in non-alcoholic fatty liver disease: The emerging view
-
Baffy, G. Kupffer cells in non-alcoholic fatty liver disease: The emerging view. J. Hepatol. 2009, 51, 212-223.
-
(2009)
J. Hepatol
, vol.51
, pp. 212-223
-
-
Baffy, G.1
-
31
-
-
73549111067
-
Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation
-
Venugopal, S. K.; Jiang, J.; Kim, T. H.; Li, Y.; Wang, S. S.; Torok, N. J.; Zern, M. A. Liver fibrosis causes downregulation of miRNA-150 and miRNA-194 in hepatic stellate cells, and their overexpression causes decreased stellate cell activation. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 298, G101-G106.
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.298
, pp. G101-G106
-
-
Venugopal, S.K.1
Jiang, J.2
Kim, T.H.3
Li, Y.4
Wang, S.S.5
Torok, N.J.6
Zern, M.A.7
-
32
-
-
13744255589
-
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
-
Duffield, J. S.; Forbes, S. J.; Constandinou, C. M.; Clay, S.; Partolina, M.; Vuthoori, S.; Wu, S.; Lang, R.; Iredale, J. P. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J. Clin. Investig. 2005, 115, 56-65.
-
(2005)
J. Clin. Investig
, vol.115
, pp. 56-65
-
-
Duffield, J.S.1
Forbes, S.J.2
Constandinou, C.M.3
Clay, S.4
Partolina, M.5
Vuthoori, S.6
Wu, S.7
Lang, R.8
Iredale, J.P.9
-
33
-
-
35948958955
-
TLR4 enhances TGF-beta signaling and hepatic fibrosis
-
Seki, E.; de Minicis, S.; Osterreicher, C. H.; Kluwe, J.; Osawa, Y.; Brenner, D. A.; Schwabe, R. F. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat. Med. 2007, 13, 1324-1332.
-
(2007)
Nat. Med
, vol.13
, pp. 1324-1332
-
-
Seki, E.1
de Minicis, S.2
Osterreicher, C.H.3
Kluwe, J.4
Osawa, Y.5
Brenner, D.A.6
Schwabe, R.F.7
|