Synergistic effects of co-administration of suicide gene expressing mesenchymal stem cells and prodrug-encapsulated liposome on aggressive lung melanoma metastases in mice

Journal of Controlled Release

Volumn 209, Issue , 2015, Pages 260-271

  Zhang, Tian Yuan ^a   Huang, Bing ^a   Wu, Hai Bin ^a   Wu, Jia He ^a   Li, Li Ming ^a   Li, Yan Xin ^a   Hu, Yu Lan ^a   Han, Min ^a   Shen, You Qing ^b   Tabata, Yasuhiko ^c   Gao, Jian Qing ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Ganciclovir; Herpes simplex virus thymidine kinase; Liposome; Melanoma metastasis; Mesenchymal stem cell; Tumor spheroid

Indexed keywords

ANTIVIRAL AGENTS; BIOLOGICAL ORGANS; CELL CULTURE; CELLS; CYTOLOGY; DERMATOLOGY; FLOWCHARTING; GENE TRANSFER; GENES; HISTOLOGY; LIPOSOMES; ONCOLOGY; PATHOLOGY; STEM CELLS; TISSUE; TUMORS; VIRUSES;

GANCICLOVIR; HERPES SIMPLEX VIRUS THYMIDINE KINASE; MELANOMA METASTASIS; MESENCHYMAL STEM CELL; TUMOR SPHEROID;

GENE THERAPY;

GANCICLOVIR; LIPOSOME; PRODRUG; ANTIVIRUS AGENT; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BYSTANDER EFFECT; CANCER GENE THERAPY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG TARGETING; GENE VECTOR; IN VITRO STUDY; LUNG METASTASIS; LUNG PARENCHYMA; MALE; MELANOMA; MESENCHYMAL STEM CELL; MOUSE; NANOENCAPSULATION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; RISK REDUCTION; SUICIDE GENE; SUICIDE GENE THERAPY; TUMOR SPHEROID; ANIMAL; C57BL MOUSE; CHEMISTRY; ENZYMOLOGY; GENE THERAPY; GENETICS; LUNG NEOPLASMS; MESENCHYMAL STEM CELL TRANSPLANTATION; PATHOLOGY; SECONDARY; SIMPLEXVIRUS; SPRAGUE DAWLEY RAT; SUICIDE TRANSGENE; TUMOR CELL LINE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE, TUMOR; GANCICLOVIR; GENES, TRANSGENIC, SUICIDE; GENETIC THERAPY; LIPOSOMES; LUNG NEOPLASMS; MALE; MELANOMA; MESENCHYMAL STEM CELL TRANSPLANTATION; MICE, INBRED C57BL; PRODRUGS; RATS, SPRAGUE-DAWLEY; SIMPLEXVIRUS; THYMIDINE KINASE;

EID: 84929321834     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.05.007     Document Type: Article

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