-
1
-
-
33749007389
-
New approaches to primary brain tumor treatment
-
Sathornsumetee S, Rich JN. New approaches to primary brain tumor treatment. Anticancer Drugs 2006;17:1003-1016.
-
(2006)
Anticancer Drugs
, vol.17
, pp. 1003-1016
-
-
Sathornsumetee, S.1
Rich, J.N.2
-
2
-
-
84860639631
-
Mesenchymal stem cells engineered for cancer therapy
-
Shah K. Mesenchymal stem cells engineered for cancer therapy. Adv Drug Deliv Rev 2012;64:739-748.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 739-748
-
-
Shah, K.1
-
3
-
-
20244374417
-
Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas
-
Nakamizo A, Marini F, Amano T et al. Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. Cancer Res 2005;65:3307-3318.
-
(2005)
Cancer Res
, vol.65
, pp. 3307-3318
-
-
Nakamizo, A.1
Marini, F.2
Amano, T.3
-
4
-
-
34250768170
-
Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene
-
Miletic H, Fischer Y, Litwak S et al. Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide gene. Mol Ther 2007;15:1373-1381.
-
(2007)
Mol Ther
, vol.15
, pp. 1373-1381
-
-
Miletic, H.1
Fischer, Y.2
Litwak, S.3
-
5
-
-
4243125420
-
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model
-
Nakamura K, Ito Y, Kawano Y et al. Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther 2004;11:1155-1164.
-
(2004)
Gene Ther
, vol.11
, pp. 1155-1164
-
-
Nakamura, K.1
Ito, Y.2
Kawano, Y.3
-
6
-
-
0038320035
-
Apo2l/trail: Apoptosis signaling, biology, and potential for cancer therapy
-
Almasan A, Ashkenazi A. Apo2l/trail: Apoptosis signaling, biology, and potential for cancer therapy. Cytokine Growth Factor Rev 2003; 14:337-348.
-
(2003)
Cytokine Growth Factor Rev
, vol.14
, pp. 337-348
-
-
Almasan, A.1
Ashkenazi, A.2
-
7
-
-
11144231673
-
Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression
-
Shah K, Bureau E, Kim DE et al. Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression. Ann Neurol 2005;57:34-41.
-
(2005)
Ann Neurol
, vol.57
, pp. 34-41
-
-
Shah, K.1
Bureau, E.2
Kim, D.E.3
-
8
-
-
85199813685
-
Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas
-
Kauer TM, Figueiredo JL, Hingtgen S et al. Encapsulated therapeutic stem cells implanted in the tumor resection cavity induce cell death in gliomas. Nat Neurosci 2011.
-
(2011)
Nat Neurosci
-
-
Kauer, T.M.1
Figueiredo, J.L.2
Hingtgen, S.3
-
9
-
-
0037832252
-
Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/ganciclovir system: Fifteen years of application
-
Fillat C, Carrio M, Cascante A et al. Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/ganciclovir system: Fifteen years of application. Curr Gene Ther 2003;3:13-26.
-
(2003)
Curr Gene Ther
, vol.3
, pp. 13-26
-
-
Fillat, C.1
Carrio, M.2
Cascante, A.3
-
10
-
-
0036324348
-
Comparison of radiolabeled nucleoside probes (fiau, fhbg, and fhpg) for pet imaging of hsv1-tk gene expression
-
Tjuvajev JG, Doubrovin M, Akhurst T et al. Comparison of radiolabeled nucleoside probes (fiau, fhbg, and fhpg) for pet imaging of hsv1-tk gene expression. J Nucl Med 2002;43:1072-1083.
-
(2002)
J Nucl Med
, vol.43
, pp. 1072-1083
-
-
Tjuvajev, J.G.1
Doubrovin, M.2
Akhurst, T.3
-
11
-
-
27744493024
-
Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging
-
Hung SC, Deng WP, Yang WK et al. Mesenchymal stem cell targeting of microscopic tumors and tumor stroma development monitored by noninvasive in vivo positron emission tomography imaging. Clin Cancer Res 2005;11:7749-7756.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7749-7756
-
-
Hung, S.C.1
Deng, W.P.2
Yang, W.K.3
-
12
-
-
0242385251
-
A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography
-
Gambhir SS, Bauer E, Black ME et al. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc Natl Acad Sci USA 2000;97:2785-2790.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2785-2790
-
-
Gambhir, S.S.1
Bauer, E.2
Black, M.E.3
-
13
-
-
17144471900
-
Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography
-
Tjuvajev JG, Avril N, Oku T et al. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 1998;58:4333-4341.
-
(1998)
Cancer Res
, vol.58
, pp. 4333-4341
-
-
Tjuvajev, J.G.1
Avril, N.2
Oku, T.3
-
14
-
-
36448942509
-
Interferon-alpha and 5-fluorouracil combination therapy after palliative hepatic resection in patients with advanced hepatocellular carcinoma, portal venous tumor thrombus in the major trunk, and multiple nodules
-
Nagano H, Miyamoto A, Wada H et al. Interferon-alpha and 5-fluorouracil combination therapy after palliative hepatic resection in patients with advanced hepatocellular carcinoma, portal venous tumor thrombus in the major trunk, and multiple nodules. Cancer 2007;110: 2493-2501.
-
(2007)
Cancer
, vol.110
, pp. 2493-2501
-
-
Nagano, H.1
Miyamoto, A.2
Wada, H.3
-
15
-
-
34447132890
-
Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy
-
Kucerova L, Altanerova V, Matuskova M et al. Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res 2007;67:6304-6313.
-
(2007)
Cancer Res
, vol.67
, pp. 6304-6313
-
-
Kucerova, L.1
Altanerova, V.2
Matuskova, M.3
-
16
-
-
74149088471
-
Adipose tissuederived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth
-
Cavarretta IT, Altanerova V, Matuskova M et al. Adipose tissuederived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth. Mol Ther 2010;18:223-231.
-
(2010)
Mol Ther
, vol.18
, pp. 223-231
-
-
Cavarretta, I.T.1
Altanerova, V.2
Matuskova, M.3
-
17
-
-
0034619328
-
Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas
-
Aboody KS, Brown A, Rainov NG et al. Neural stem cells display extensive tropism for pathology in adult brain: Evidence from intracranial gliomas. Proc Natl Acad Sci USA 2000;97:12846-12851.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12846-12851
-
-
Aboody, K.S.1
Brown, A.2
Rainov, N.G.3
-
18
-
-
77951100891
-
Human neural stem cells transduced with ifn-beta and cytosine deaminase genes intensify bystander effect in experimental glioma
-
Ito S, Natsume A, Shimato S et al. Human neural stem cells transduced with ifn-beta and cytosine deaminase genes intensify bystander effect in experimental glioma. Cancer Gene Ther 2010;17:299-306.
-
(2010)
Cancer Gene Ther
, vol.17
, pp. 299-306
-
-
Ito, S.1
Natsume, A.2
Shimato, S.3
-
19
-
-
67650127424
-
Stem cells as vectors to deliver hsv/tk gene therapy for malignant gliomas
-
Rath P, Shi H, Maruniak JA et al. Stem cells as vectors to deliver hsv/tk gene therapy for malignant gliomas. Curr Stem Cell Res Ther 2009;4:44-49.
-
(2009)
Curr Stem Cell Res Ther
, vol.4
, pp. 44-49
-
-
Rath, P.1
Shi, H.2
Maruniak, J.A.3
-
20
-
-
63849148548
-
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
-
Sasportas LS, Kasmieh R, Wakimoto H et al. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci USA 2009;106:4822-4827.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4822-4827
-
-
Sasportas, L.S.1
Kasmieh, R.2
Wakimoto, H.3
-
21
-
-
7944234370
-
Optimized large-scale production of high titer lentivirus vector pseudotypes
-
Sena-Esteves M, Tebbets JC, Steffens S et al. Optimized large-scale production of high titer lentivirus vector pseudotypes. J Virol Methods 2004;122:131-139.
-
(2004)
J Virol Methods
, vol.122
, pp. 131-139
-
-
Sena-Esteves, M.1
Tebbets, J.C.2
Steffens, S.3
-
22
-
-
43749114031
-
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model
-
Shah K, Hingtgen S, Kasmieh R et al. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci 2008;28:4406-4413.
-
(2008)
J Neurosci
, vol.28
, pp. 4406-4413
-
-
Shah, K.1
Hingtgen, S.2
Kasmieh, R.3
-
23
-
-
35148900227
-
Microrna-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered s-trail in human gliomas
-
Corsten MF, Miranda R, Kasmieh R et al. Microrna-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered s-trail in human gliomas. Cancer Res 2007;67:8994-9000.
-
(2007)
Cancer Res
, vol.67
, pp. 8994-9000
-
-
Corsten, M.F.1
Miranda, R.2
Kasmieh, R.3
-
24
-
-
67649171661
-
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein tsg-6
-
Lee RH, Pulin AA, Seo MJ et al. Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein tsg-6. Cell Stem Cell 2009;5:54-63.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 54-63
-
-
Lee, R.H.1
Pulin, A.A.2
Seo, M.J.3
-
25
-
-
67651011690
-
Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy
-
Uchibori R, Okada T, Ito T et al. Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy. J Gene Med 2009;11:373-381.
-
(2009)
J Gene Med
, vol.11
, pp. 373-381
-
-
Uchibori, R.1
Okada, T.2
Ito, T.3
-
26
-
-
57149088465
-
Gene therapy using trail-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma
-
Kim SM, Lim JY, Park SI et al. Gene therapy using trail-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. Cancer Res 2008;68:9614-9623.
-
(2008)
Cancer Res
, vol.68
, pp. 9614-9623
-
-
Kim, S.M.1
Lim, J.Y.2
Park, S.I.3
-
27
-
-
50349092260
-
A phase 1 study of mapatumumab (fully human monoclonal antibody to trail-r1) in patients with advanced solid malignancies
-
Hotte SJ, Hirte HW, Chen EX et al. A phase 1 study of mapatumumab (fully human monoclonal antibody to trail-r1) in patients with advanced solid malignancies. Clin Cancer Res 2008;14:3450-3455.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3450-3455
-
-
Hotte, S.J.1
Hirte, H.W.2
Chen, E.X.3
-
28
-
-
45649084324
-
Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the trail receptor-1, in patients with advanced non-small cell lung cancer
-
Greco FA, Bonomi P, Crawford J et al. Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the trail receptor-1, in patients with advanced non-small cell lung cancer. Lung Cancer 2008;61:82-90.
-
(2008)
Lung Cancer
, vol.61
, pp. 82-90
-
-
Greco, F.A.1
Bonomi, P.2
Crawford, J.3
-
29
-
-
84857050976
-
Quantifying heterogeneity in human tumours using MRI and PET
-
Asselin MC, O'Connor JP, Boellaard R et al. Quantifying heterogeneity in human tumours using MRI and PET. Eur J Cancer 2012;48: 447-455.
-
(2012)
Eur J Cancer
, vol.48
, pp. 447-455
-
-
Asselin, M.C.1
O'Connor, J.P.2
Boellaard, R.3
-
30
-
-
60449099546
-
Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo
-
Tyler MA, Ulasov IV, Sonabend AM et al. Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo. Gene Ther 2009;16:262-278.
-
(2009)
Gene Ther
, vol.16
, pp. 262-278
-
-
Tyler, M.A.1
Ulasov, I.V.2
Sonabend, A.M.3
-
31
-
-
80052406372
-
Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma
-
Ahmed AU, Thaci B, Alexiades NG et al. Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma. Mol Ther 2011;19: 1714-1726.
-
(2011)
Mol Ther
, vol.19
, pp. 1714-1726
-
-
Ahmed, A.U.1
Thaci, B.2
Alexiades, N.G.3
-
32
-
-
84861195591
-
Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: Targeted delivery of the therapeutic payload in an orthotopic brain tumor model
-
Thaci B, Ahmed AU, Ulasov IV et al. Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: Targeted delivery of the therapeutic payload in an orthotopic brain tumor model. Cancer Gene Ther 2012;19:431-442.
-
(2012)
Cancer Gene Ther
, vol.19
, pp. 431-442
-
-
Thaci, B.1
Ahmed, A.U.2
Ulasov, I.V.3
-
33
-
-
34948896045
-
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
-
Karnoub AE, Dash AB, Vo AP et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007;449: 557-563.
-
(2007)
Nature
, vol.449
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
-
34
-
-
33646502840
-
Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo
-
Zhu W, Xu W, Jiang R et al. Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo. Exp Mol Pathol 2006; 80:267-274.
-
(2006)
Exp Mol Pathol
, vol.80
, pp. 267-274
-
-
Zhu, W.1
Xu, W.2
Jiang, R.3
-
35
-
-
80155213401
-
Selective targeting of genetically engineered mesenchymal stem cells to tumor stroma microenvironments using tissue-specific suicide gene expression suppresses growth of hepatocellular carcinoma
-
discussion 774-765
-
Niess H, Bao Q, Conrad C et al. Selective targeting of genetically engineered mesenchymal stem cells to tumor stroma microenvironments using tissue-specific suicide gene expression suppresses growth of hepatocellular carcinoma. Ann Surg 2011;254:767-774, discussion 774-765.
-
(2011)
Ann Surg
, vol.254
, pp. 767-774
-
-
Niess, H.1
Bao, Q.2
Conrad, C.3
-
36
-
-
77956627600
-
An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies
-
Ramos CA, Asgari Z, Liu E et al. An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies. Stem Cells 2010;28:1107-1115.
-
(2010)
Stem Cells
, vol.28
, pp. 1107-1115
-
-
Ramos, C.A.1
Asgari, Z.2
Liu, E.3
-
37
-
-
68449099297
-
Long term non-invasive imaging of embryonic stem cells using reporter genes
-
Sun N, Lee A, Wu JC. Long term non-invasive imaging of embryonic stem cells using reporter genes. Nat Protoc 2009;4:1192-1201.
-
(2009)
Nat Protoc
, vol.4
, pp. 1192-1201
-
-
Sun, N.1
Lee, A.2
Wu, J.C.3
-
38
-
-
0029609610
-
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug cb1954
-
Bridgewater JA, Springer CJ, Knox RJ et al. Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug cb1954. Eur J Cancer 1995; 31A:2362-2370.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 2362-2370
-
-
Bridgewater, J.A.1
Springer, C.J.2
Knox, R.J.3
-
39
-
-
33845733149
-
Targeting the cyp2b 1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models
-
Huch M, Abate-Daga D, Roig JM et al. Targeting the cyp2b 1/cyclophosphamide suicide system to fibroblast growth factor receptors results in a potent antitumoral response in pancreatic cancer models. Hum Gene Ther 2006;17:1187-1200.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 1187-1200
-
-
Huch, M.1
Abate-Daga, D.2
Roig, J.M.3
-
40
-
-
84859819546
-
Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response
-
Alieva M, Bago JR, Aguilar E et al. Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response. Plos One 2012;7:e35148.
-
(2012)
Plos One
, vol.7
-
-
Alieva, M.1
Bago, J.R.2
Aguilar, E.3
-
41
-
-
84856351601
-
Imaging modalities for the staging of patients with colorectal cancer
-
Bipat S, Niekel MC, Comans EF et al. Imaging modalities for the staging of patients with colorectal cancer. Neth J Med 2012;70:26-34.
-
(2012)
Neth J Med
, vol.70
, pp. 26-34
-
-
Bipat, S.1
Niekel, M.C.2
Comans, E.F.3
-
42
-
-
80052228530
-
Opportunities and pitfalls of cancer imaging in clinical trials
-
Morgan B. Opportunities and pitfalls of cancer imaging in clinical trials. Nat Rev Clin Oncol 2011;8:517-527.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 517-527
-
-
Morgan, B.1
-
43
-
-
70349645398
-
Iron labeling and pre-clinical mri visualization of therapeutic human neural stem cells in a murine glioma model
-
Thu MS, Najbauer J, Kendall SE et al. Iron labeling and pre-clinical mri visualization of therapeutic human neural stem cells in a murine glioma model. Plos One 2009;4:e7218.
-
(2009)
Plos One
, vol.4
-
-
Thu, M.S.1
Najbauer, J.2
Kendall, S.E.3
-
44
-
-
71549114206
-
Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles
-
Loebinger MR, Kyrtatos PG, Turmaine M et al. Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles. Cancer Res 2009;69: 8862-8867.
-
(2009)
Cancer Res
, vol.69
, pp. 8862-8867
-
-
Loebinger, M.R.1
Kyrtatos, P.G.2
Turmaine, M.3
-
45
-
-
47949083824
-
In vitro model of bromodeoxyuridine or iron oxide nanoparticle uptake by activated macrophages from labeled stem cells: Implications for cellular therapy
-
Pawelczyk E, Arbab AS, Chaudhry A et al. In vitro model of bromodeoxyuridine or iron oxide nanoparticle uptake by activated macrophages from labeled stem cells: Implications for cellular therapy. Stem Cells 2008;26:1366-1375.
-
(2008)
Stem Cells
, vol.26
, pp. 1366-1375
-
-
Pawelczyk, E.1
Arbab, A.S.2
Chaudhry, A.3
-
46
-
-
34748907948
-
Iron-oxide labeling and outcome of transplanted mesenchymal stem cells in the infarcted myocardium
-
Amsalem Y, Mardor Y, Feinberg MS et al. Iron-oxide labeling and outcome of transplanted mesenchymal stem cells in the infarcted myocardium. Circulation 2007;116:I38-45.
-
(2007)
Circulation
, vol.116
-
-
Amsalem, Y.1
Mardor, Y.2
Feinberg, M.S.3
-
47
-
-
41249090855
-
Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart
-
Terrovitis J, Stuber M, Youssef A et al. Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart. Circulation 2008;117:1555-1562.
-
(2008)
Circulation
, vol.117
, pp. 1555-1562
-
-
Terrovitis, J.1
Stuber, M.2
Youssef, A.3
|