-
1
-
-
84923035739
-
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes
-
M. Baxter, S. Withey, S. Harrison, C.-P. Segeritz, F. Zhang, R. Atkinson-Dell, C. Rowe, D.T. Gerrard, R. Sison-Young, and R. Jenkins Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes J. Hepatol. 62 2015 581 589
-
(2015)
J. Hepatol.
, vol.62
, pp. 581-589
-
-
Baxter, M.1
Withey, S.2
Harrison, S.3
Segeritz, C.-P.4
Zhang, F.5
Atkinson-Dell, R.6
Rowe, C.7
Gerrard, D.T.8
Sison-Young, R.9
Jenkins, R.10
-
2
-
-
0023898432
-
Molecular basis of alpha-1-antitrypsin deficiency
-
M. Brantly, T. Nukiwa, and R.G. Crystal Molecular basis of alpha-1-antitrypsin deficiency Am. J. Med. 84 6A 1988 13 31
-
(1988)
Am. J. Med.
, vol.84
, Issue.A6
, pp. 13-31
-
-
Brantly, M.1
Nukiwa, T.2
Crystal, R.G.3
-
3
-
-
77952770299
-
Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency
-
T.P. Carroll, C.M. Greene, C.A. O'Connor, A.M. Nolan, S.J. O'Neill, and N.G. McElvaney Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency J. Immunol. 184 2010 4538 4546
-
(2010)
J. Immunol.
, vol.184
, pp. 4538-4546
-
-
Carroll, T.P.1
Greene, C.M.2
O'Connor, C.A.3
Nolan, A.M.4
O'Neill, S.J.5
McElvaney, N.G.6
-
4
-
-
84859527233
-
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells
-
X. Cheng, L. Ying, L. Lu, A.M. Galvão, J.A. Mills, H.C. Lin, D.N. Kotton, S.S. Shen, M.C. Nostro, and J.K. Choi Self-renewing endodermal progenitor lines generated from human pluripotent stem cells Cell Stem Cell 10 2012 371 384
-
(2012)
Cell Stem Cell
, vol.10
, pp. 371-384
-
-
Cheng, X.1
Ying, L.2
Lu, L.3
Galvão, A.M.4
Mills, J.A.5
Lin, H.C.6
Kotton, D.N.7
Shen, S.S.8
Nostro, M.C.9
Choi, J.K.10
-
5
-
-
84879116702
-
Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells
-
S.M. Choi, Y. Kim, J.S. Shim, J.T. Park, R.-H. Wang, S.D. Leach, J.O. Liu, C. Deng, Z. Ye, and Y.-Y. Jang Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells Hepatology 57 2013 2458 2468
-
(2013)
Hepatology
, vol.57
, pp. 2458-2468
-
-
Choi, S.M.1
Kim, Y.2
Shim, J.S.3
Park, J.T.4
Wang, R.-H.5
Leach, S.D.6
Liu, J.O.7
Deng, C.8
Ye, Z.9
Jang, Y.-Y.10
-
6
-
-
79957926957
-
Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes
-
C. Christodoulou, T.A. Longmire, S.S. Shen, A. Bourdon, C.A. Sommer, P. Gadue, A. Spira, V. Gouon-Evans, G.J. Murphy, G. Mostoslavsky, and D.N. Kotton Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes J. Clin. Invest. 121 2011 2313 2325
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2313-2325
-
-
Christodoulou, C.1
Longmire, T.A.2
Shen, S.S.3
Bourdon, A.4
Sommer, C.A.5
Gadue, P.6
Spira, A.7
Gouon-Evans, V.8
Murphy, G.J.9
Mostoslavsky, G.10
Kotton, D.N.11
-
7
-
-
0025350658
-
Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy
-
R.G. Crystal Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy J. Clin. Invest. 85 1990 1343 1352
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 1343-1352
-
-
Crystal, R.G.1
-
8
-
-
0036433482
-
Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: Summary of an analysis of published genetic epidemiologic surveys
-
F.J. de Serres Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys Chest 122 2002 1818 1829
-
(2002)
Chest
, vol.122
, pp. 1818-1829
-
-
De Serres, F.J.1
-
9
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
A.D. Ebert, J. Yu, F.F. Rose Jr., V.B. Mattis, C.L. Lorson, J.A. Thomson, and C.N. Svendsen Induced pluripotent stem cells from a spinal muscular atrophy patient Nature 457 2009 277 280
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, Jr.F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
10
-
-
0022637178
-
Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency
-
S. Eriksson, J. Carlson, and R. Velez Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency N. Engl. J. Med. 314 1986 736 739
-
(1986)
N. Engl. J. Med.
, vol.314
, pp. 736-739
-
-
Eriksson, S.1
Carlson, J.2
Velez, R.3
-
11
-
-
0025258970
-
Accumulation of the insoluble PiZ variant of human alpha 1-antitrypsin within the hepatic endoplasmic reticulum does not elevate the steady-state level of grp78/BiP
-
K.S. Graham, A. Le, and R.N. Sifers Accumulation of the insoluble PiZ variant of human alpha 1-antitrypsin within the hepatic endoplasmic reticulum does not elevate the steady-state level of grp78/BiP J. Biol. Chem. 265 1990 20463 20468
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20463-20468
-
-
Graham, K.S.1
Le, A.2
Sifers, R.N.3
-
12
-
-
28244499949
-
Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response
-
T. Hidvegi, B.Z. Schmidt, P. Hale, and D.H. Perlmutter Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response J. Biol. Chem. 280 2005 39002 39015
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39002-39015
-
-
Hidvegi, T.1
Schmidt, B.Z.2
Hale, P.3
Perlmutter, D.H.4
-
13
-
-
77954597127
-
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
-
T. Hidvegi, M. Ewing, P. Hale, C. Dippold, C. Beckett, C. Kemp, N. Maurice, A. Mukherjee, C. Goldbach, and S. Watkins An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis Science 329 2010 229 232
-
(2010)
Science
, vol.329
, pp. 229-232
-
-
Hidvegi, T.1
Ewing, M.2
Hale, P.3
Dippold, C.4
Beckett, C.5
Kemp, C.6
Maurice, N.7
Mukherjee, A.8
Goldbach, C.9
Watkins, S.10
-
14
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
-
J. Hitomi, T. Katayama, Y. Eguchi, T. Kudo, M. Taniguchi, Y. Koyama, T. Manabe, S. Yamagishi, Y. Bando, and K. Imaizumi Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death J. Cell Biol. 165 2004 347 356
-
(2004)
J. Cell Biol.
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
-
15
-
-
84864508175
-
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
-
M. Kajiwara, T. Aoi, K. Okita, R. Takahashi, H. Inoue, N. Takayama, H. Endo, K. Eto, J. Toguchida, S. Uemoto, and S. Yamanaka Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells Proc. Natl. Acad. Sci. USA 109 2012 12538 12543
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 12538-12543
-
-
Kajiwara, M.1
Aoi, T.2
Okita, K.3
Takahashi, R.4
Inoue, H.5
Takayama, N.6
Endo, H.7
Eto, K.8
Toguchida, J.9
Uemoto, S.10
Yamanaka, S.11
-
16
-
-
1442321303
-
Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2
-
M. Kaneko, Y. Niinuma, and Y. Nomura Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2 Biol. Pharm. Bull. 26 2003 931 935
-
(2003)
Biol. Pharm. Bull.
, vol.26
, pp. 931-935
-
-
Kaneko, M.1
Niinuma, Y.2
Nomura, Y.3
-
17
-
-
2142768895
-
Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency
-
M.W. Lawless, C.M. Greene, A.T. Mulgrew, C.C. Taggart, S.J. O'Neill, and N.G. McElvaney Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency J. Immunol. 172 2004 5722 5726
-
(2004)
J. Immunol.
, vol.172
, pp. 5722-5726
-
-
Lawless, M.W.1
Greene, C.M.2
Mulgrew, A.T.3
Taggart, C.C.4
O'Neill, S.J.5
McElvaney, N.G.6
-
18
-
-
84888130571
-
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis
-
A. Leung, S.K. Nah, W. Reid, A. Ebata, C.M. Koch, S. Monti, J.C. Genereux, R.L. Wiseman, B. Wolozin, and L.H. Connors Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis Stem Cell Reports 1 2013 451 463
-
(2013)
Stem Cell Reports
, vol.1
, pp. 451-463
-
-
Leung, A.1
Nah, S.K.2
Reid, W.3
Ebata, A.4
Koch, C.M.5
Monti, S.6
Genereux, J.C.7
Wiseman, R.L.8
Wolozin, B.9
Connors, L.H.10
-
19
-
-
0026755363
-
The mechanism of Z alpha 1-antitrypsin accumulation in the liver
-
D.A. Lomas, D.L. Evans, J.T. Finch, and R.W. Carrell The mechanism of Z alpha 1-antitrypsin accumulation in the liver Nature 357 1992 605 607
-
(1992)
Nature
, vol.357
, pp. 605-607
-
-
Lomas, D.A.1
Evans, D.L.2
Finch, J.T.3
Carrell, R.W.4
-
20
-
-
84887583032
-
Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines
-
J.A. Mills, K. Wang, P. Paluru, L. Ying, L. Lu, A.M. Galvão, D. Xu, Y. Yao, S.K. Sullivan, and L.M. Sullivan Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines Blood 122 2013 2047 2051
-
(2013)
Blood
, vol.122
, pp. 2047-2051
-
-
Mills, J.A.1
Wang, K.2
Paluru, P.3
Ying, L.4
Lu, L.5
Galvão, A.M.6
Xu, D.7
Yao, Y.8
Sullivan, S.K.9
Sullivan, L.M.10
-
21
-
-
79953267538
-
A bioinformatic assay for pluripotency in human cells
-
F.-J. Müller, B.M. Schuldt, R. Williams, D. Mason, G. Altun, E.P. Papapetrou, S. Danner, J.E. Goldmann, A. Herbst, and N.O. Schmidt A bioinformatic assay for pluripotency in human cells Nat. Methods 8 2011 315 317
-
(2011)
Nat. Methods
, vol.8
, pp. 315-317
-
-
Müller, F.-J.1
Schuldt, B.M.2
Williams, R.3
Mason, D.4
Altun, G.5
Papapetrou, E.P.6
Danner, S.7
Goldmann, J.E.8
Herbst, A.9
Schmidt, N.O.10
-
22
-
-
84880312802
-
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes
-
S. Ogawa, J. Surapisitchat, C. Virtanen, M. Ogawa, M. Niapour, K.S. Sugamori, S. Wang, L. Tamblyn, C. Guillemette, and E. Hoffmann Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes Development 140 2013 3285 3296
-
(2013)
Development
, vol.140
, pp. 3285-3296
-
-
Ogawa, S.1
Surapisitchat, J.2
Virtanen, C.3
Ogawa, M.4
Niapour, M.5
Sugamori, K.S.6
Wang, S.7
Tamblyn, L.8
Guillemette, C.9
Hoffmann, E.10
-
23
-
-
84876803937
-
Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency
-
A. Ordóñez, E.L. Snapp, L. Tan, E. Miranda, S.J. Marciniak, and D.A. Lomas Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency Hepatology 57 2013 2049 2060
-
(2013)
Hepatology
, vol.57
, pp. 2049-2060
-
-
Ordóñez, A.1
Snapp, E.L.2
Tan, L.3
Miranda, E.4
Marciniak, S.J.5
Lomas, D.A.6
-
24
-
-
0029001576
-
A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B
-
H.L. Pahl, and P.A. Baeuerle A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B EMBO J. 14 1995 2580 2588
-
(1995)
EMBO J.
, vol.14
, pp. 2580-2588
-
-
Pahl, H.L.1
Baeuerle, P.A.2
-
25
-
-
67651154714
-
Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase i modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency
-
S. Pan, L. Huang, J. McPherson, D. Muzny, F. Rouhani, M. Brantly, R. Gibbs, and R.N. Sifers Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency Hepatology 50 2009 275 281
-
(2009)
Hepatology
, vol.50
, pp. 275-281
-
-
Pan, S.1
Huang, L.2
McPherson, J.3
Muzny, D.4
Rouhani, F.5
Brantly, M.6
Gibbs, R.7
Sifers, R.N.8
-
26
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
I.-H. Park, N. Arora, H. Huo, N. Maherali, T. Ahfeldt, A. Shimamura, M.W. Lensch, C. Cowan, K. Hochedlinger, and G.Q. Daley Disease-specific induced pluripotent stem cells Cell 134 2008 877 886
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.-H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
27
-
-
0024463472
-
The alpha 1-antitrypsin gene and emphysema
-
D.H. Perlmutter, and J.A. Pierce The alpha 1-antitrypsin gene and emphysema Am. J. Physiol. 257 1989 L147 L162
-
(1989)
Am. J. Physiol.
, vol.257
, pp. L147-L162
-
-
Perlmutter, D.H.1
Pierce, J.A.2
-
28
-
-
34248642305
-
Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: A meeting review
-
D.H. Perlmutter, J.L. Brodsky, W.F. Balistreri, and B.C. Trapnell Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review Hepatology 45 2007 1313 1323
-
(2007)
Hepatology
, vol.45
, pp. 1313-1323
-
-
Perlmutter, D.H.1
Brodsky, J.L.2
Balistreri, W.F.3
Trapnell, B.C.4
-
29
-
-
77956354416
-
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells
-
S.T. Rashid, S. Corbineau, N. Hannan, S.J. Marciniak, E. Miranda, G. Alexander, I. Huang-Doran, J. Griffin, L. Ahrlund-Richter, and J. Skepper Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells J. Clin. Invest. 120 2010 3127 3136
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3127-3136
-
-
Rashid, S.T.1
Corbineau, S.2
Hannan, N.3
Marciniak, S.J.4
Miranda, E.5
Alexander, G.6
Huang-Doran, I.7
Griffin, J.8
Ahrlund-Richter, L.9
Skepper, J.10
-
30
-
-
84880916761
-
Identification of small molecules for human hepatocyte expansion and iPS differentiation
-
J. Shan, R.E. Schwartz, N.T. Ross, D.J. Logan, D. Thomas, S.A. Duncan, T.E. North, W. Goessling, A.E. Carpenter, and S.N. Bhatia Identification of small molecules for human hepatocyte expansion and iPS differentiation Nat. Chem. Biol. 9 2013 514 520
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 514-520
-
-
Shan, J.1
Schwartz, R.E.2
Ross, N.T.3
Logan, D.J.4
Thomas, D.5
Duncan, S.A.6
North, T.E.7
Goessling, W.8
Carpenter, A.E.9
Bhatia, S.N.10
-
31
-
-
73449100783
-
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
-
K. Si-Tayeb, F.K. Noto, M. Nagaoka, J. Li, M.A. Battle, C. Duris, P.E. North, S. Dalton, and S.A. Duncan Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells Hepatology 51 2010 297 305
-
(2010)
Hepatology
, vol.51
, pp. 297-305
-
-
Si-Tayeb, K.1
Noto, F.K.2
Nagaoka, M.3
Li, J.4
Battle, M.A.5
Duris, C.6
North, P.E.7
Dalton, S.8
Duncan, S.A.9
-
32
-
-
84903437158
-
Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes
-
A.-K.M. Sjogren, M. Liljevald, B. Glinghammar, J. Sagemark, X.-Q. Li, A. Jonebring, I. Cotgreave, G. Brolén, and T.B. Andersson Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes Arch. Toxicol. 88 2014 1427 1437
-
(2014)
Arch. Toxicol.
, vol.88
, pp. 1427-1437
-
-
Sjogren, A.-K.M.1
Liljevald, M.2
Glinghammar, B.3
Sagemark, J.4
Li, X.-Q.5
Jonebring, A.6
Cotgreave, I.7
Brolén, G.8
Andersson, T.B.9
-
33
-
-
84884653774
-
The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation
-
B.W. Smith, S.S. Rozelle, A. Leung, J. Ubellacker, A. Parks, S.K. Nah, D. French, P. Gadue, S. Monti, and D.H.K. Chui The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation Blood 122 2013 376 385
-
(2013)
Blood
, vol.122
, pp. 376-385
-
-
Smith, B.W.1
Rozelle, S.S.2
Leung, A.3
Ubellacker, J.4
Parks, A.5
Nah, S.K.6
French, D.7
Gadue, P.8
Monti, S.9
Chui, D.H.K.10
-
34
-
-
77958082207
-
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette
-
A. Somers, J.-C. Jean, C.A. Sommer, A. Omari, C.C. Ford, J.A. Mills, L. Ying, A.G. Sommer, J.M. Jean, and B.W. Smith Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette Stem Cells 28 2010 1728 1740
-
(2010)
Stem Cells
, vol.28
, pp. 1728-1740
-
-
Somers, A.1
Jean, J.-C.2
Sommer, C.A.3
Omari, A.4
Ford, C.C.5
Mills, J.A.6
Ying, L.7
Sommer, A.G.8
Jean, J.M.9
Smith, B.W.10
-
35
-
-
84892645746
-
Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis
-
T. Suzuki, C. Mayhew, A. Sallese, C. Chalk, B.C. Carey, P. Malik, R.E. Wood, and B.C. Trapnell Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis Am. J. Respir. Crit. Care Med. 189 2014 183 193
-
(2014)
Am. J. Respir. Crit. Care Med.
, vol.189
, pp. 183-193
-
-
Suzuki, T.1
Mayhew, C.2
Sallese, A.3
Chalk, C.4
Carey, B.C.5
Malik, P.6
Wood, R.E.7
Trapnell, B.C.8
-
36
-
-
84887152893
-
Accurate prediction of drug-induced liver injury using stem cell-derived populations
-
D. Szkolnicka, S.L. Farnworth, B. Lucendo-Villarin, C. Storck, W. Zhou, J.P. Iredale, O. Flint, and D.C. Hay Accurate prediction of drug-induced liver injury using stem cell-derived populations Stem Cells Transl. Med. 3 2014 141 148
-
(2014)
Stem Cells Transl. Med.
, vol.3
, pp. 141-148
-
-
Szkolnicka, D.1
Farnworth, S.L.2
Lucendo-Villarin, B.3
Storck, C.4
Zhou, W.5
Iredale, J.P.6
Flint, O.7
Hay, D.C.8
-
37
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
38
-
-
0033671965
-
Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response
-
J.H. Teckman, and D.H. Perlmutter Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response Am. J. Physiol. Gastrointest. Liver Physiol. 279 2000 G961 G974
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.279
, pp. G961-G974
-
-
Teckman, J.H.1
Perlmutter, D.H.2
-
40
-
-
84872238836
-
Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics
-
C. Terrenoire, K. Wang, K.W. Tung, W.K. Chung, R.H. Pass, J.T. Lu, J.C. Jean, A. Omari, K.J. Sampson, and D.N. Kotton Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics J. Gen. Physiol. 141 2013 61 72
-
(2013)
J. Gen. Physiol.
, vol.141
, pp. 61-72
-
-
Terrenoire, C.1
Wang, K.2
Tung, K.W.3
Chung, W.K.4
Pass, R.H.5
Lu, J.T.6
Jean, J.C.7
Omari, A.8
Sampson, K.J.9
Kotton, D.N.10
-
41
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
G. Twig, A. Elorza, A.J.A. Molina, H. Mohamed, J.D. Wikstrom, G. Walzer, L. Stiles, S.E. Haigh, S. Katz, and G. Las Fission and selective fusion govern mitochondrial segregation and elimination by autophagy EMBO J. 27 2008 433 446
-
(2008)
EMBO J.
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.A.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
-
42
-
-
48649084090
-
Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells
-
A.A. Wilson, L.W. Kwok, A.-H. Hovav, S.J. Ohle, F.F. Little, A. Fine, and D.N. Kotton Sustained expression of alpha1-antitrypsin after transplantation of manipulated hematopoietic stem cells Am. J. Respir. Cell Mol. Biol. 39 2008 133 141
-
(2008)
Am. J. Respir. Cell Mol. Biol.
, vol.39
, pp. 133-141
-
-
Wilson, A.A.1
Kwok, L.W.2
Hovav, A.-H.3
Ohle, S.J.4
Little, F.F.5
Fine, A.6
Kotton, D.N.7
-
43
-
-
74949132576
-
Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
-
A.A. Wilson, G.J. Murphy, H. Hamakawa, L.W. Kwok, S. Srinivasan, A.-H. Hovav, R.C. Mulligan, S. Amar, B. Suki, and D.N. Kotton Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages J. Clin. Invest. 120 2010 379 389
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 379-389
-
-
Wilson, A.A.1
Murphy, G.J.2
Hamakawa, H.3
Kwok, L.W.4
Srinivasan, S.5
Hovav, A.-H.6
Mulligan, R.C.7
Amar, S.8
Suki, B.9
Kotton, D.N.10
-
44
-
-
0028593988
-
A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency
-
Y. Wu, I. Whitman, E. Molmenti, K. Moore, P. Hippenmeyer, and D.H. Perlmutter A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency Proc. Natl. Acad. Sci. USA 91 1994 9014 9018
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9014-9018
-
-
Wu, Y.1
Whitman, I.2
Molmenti, E.3
Moore, K.4
Hippenmeyer, P.5
Perlmutter, D.H.6
-
45
-
-
80054987997
-
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
-
K. Yusa, S.T. Rashid, H. Strick-Marchand, I. Varela, P.-Q. Liu, D.E. Paschon, E. Miranda, A. Ordóñez, N.R.F. Hannan, and F.J. Rouhani Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells Nature 478 2011 391 394
-
(2011)
Nature
, vol.478
, pp. 391-394
-
-
Yusa, K.1
Rashid, S.T.2
Strick-Marchand, H.3
Varela, I.4
Liu, P.-Q.5
Paschon, D.E.6
Miranda, E.7
Ordóñez, A.8
Hannan, N.R.F.9
Rouhani, F.J.10
|