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Volumn 4, Issue 5, 2015, Pages 873-885

Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells

(24)  Wilson, Andrew A a   Ying, Lei b   Liesa, Marc c   Segeritz, Charis Patricia d   Mills, Jason A b   Shen, Steven S c   Jean, Jyhchang a   Lonza, Geordie C a   Liberti, Derek C a   Lang, Alex H e   Nazaire, Jean c   Gower, Adam C c   Müeller, Franz Josef f   Mehta, Pankaj e   Ordóñez, Adriana g   Lomas, David A g   Vallier, Ludovic d   Murphy, George J a   Mostoslavsky, Gustavo a   Spira, Avrum c   more..


Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; MUTANT PROTEIN; TRANSCRIPTOME; ALPHA 1 ANTITRYPSIN;

EID: 84929282245     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.02.021     Document Type: Article
Times cited : (72)

References (45)
  • 2
    • 0023898432 scopus 로고
    • Molecular basis of alpha-1-antitrypsin deficiency
    • M. Brantly, T. Nukiwa, and R.G. Crystal Molecular basis of alpha-1-antitrypsin deficiency Am. J. Med. 84 6A 1988 13 31
    • (1988) Am. J. Med. , vol.84 , Issue.A6 , pp. 13-31
    • Brantly, M.1    Nukiwa, T.2    Crystal, R.G.3
  • 3
    • 77952770299 scopus 로고    scopus 로고
    • Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency
    • T.P. Carroll, C.M. Greene, C.A. O'Connor, A.M. Nolan, S.J. O'Neill, and N.G. McElvaney Evidence for unfolded protein response activation in monocytes from individuals with alpha-1 antitrypsin deficiency J. Immunol. 184 2010 4538 4546
    • (2010) J. Immunol. , vol.184 , pp. 4538-4546
    • Carroll, T.P.1    Greene, C.M.2    O'Connor, C.A.3    Nolan, A.M.4    O'Neill, S.J.5    McElvaney, N.G.6
  • 7
    • 0025350658 scopus 로고
    • Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy
    • R.G. Crystal Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy J. Clin. Invest. 85 1990 1343 1352
    • (1990) J. Clin. Invest. , vol.85 , pp. 1343-1352
    • Crystal, R.G.1
  • 8
    • 0036433482 scopus 로고    scopus 로고
    • Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: Summary of an analysis of published genetic epidemiologic surveys
    • F.J. de Serres Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys Chest 122 2002 1818 1829
    • (2002) Chest , vol.122 , pp. 1818-1829
    • De Serres, F.J.1
  • 10
    • 0022637178 scopus 로고
    • Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency
    • S. Eriksson, J. Carlson, and R. Velez Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency N. Engl. J. Med. 314 1986 736 739
    • (1986) N. Engl. J. Med. , vol.314 , pp. 736-739
    • Eriksson, S.1    Carlson, J.2    Velez, R.3
  • 11
    • 0025258970 scopus 로고
    • Accumulation of the insoluble PiZ variant of human alpha 1-antitrypsin within the hepatic endoplasmic reticulum does not elevate the steady-state level of grp78/BiP
    • K.S. Graham, A. Le, and R.N. Sifers Accumulation of the insoluble PiZ variant of human alpha 1-antitrypsin within the hepatic endoplasmic reticulum does not elevate the steady-state level of grp78/BiP J. Biol. Chem. 265 1990 20463 20468
    • (1990) J. Biol. Chem. , vol.265 , pp. 20463-20468
    • Graham, K.S.1    Le, A.2    Sifers, R.N.3
  • 12
    • 28244499949 scopus 로고    scopus 로고
    • Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response
    • T. Hidvegi, B.Z. Schmidt, P. Hale, and D.H. Perlmutter Accumulation of mutant alpha1-antitrypsin Z in the endoplasmic reticulum activates caspases-4 and -12, NFkappaB, and BAP31 but not the unfolded protein response J. Biol. Chem. 280 2005 39002 39015
    • (2005) J. Biol. Chem. , vol.280 , pp. 39002-39015
    • Hidvegi, T.1    Schmidt, B.Z.2    Hale, P.3    Perlmutter, D.H.4
  • 16
    • 1442321303 scopus 로고    scopus 로고
    • Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2
    • M. Kaneko, Y. Niinuma, and Y. Nomura Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2 Biol. Pharm. Bull. 26 2003 931 935
    • (2003) Biol. Pharm. Bull. , vol.26 , pp. 931-935
    • Kaneko, M.1    Niinuma, Y.2    Nomura, Y.3
  • 17
    • 2142768895 scopus 로고    scopus 로고
    • Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency
    • M.W. Lawless, C.M. Greene, A.T. Mulgrew, C.C. Taggart, S.J. O'Neill, and N.G. McElvaney Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z alpha 1-antitrypsin deficiency J. Immunol. 172 2004 5722 5726
    • (2004) J. Immunol. , vol.172 , pp. 5722-5726
    • Lawless, M.W.1    Greene, C.M.2    Mulgrew, A.T.3    Taggart, C.C.4    O'Neill, S.J.5    McElvaney, N.G.6
  • 19
    • 0026755363 scopus 로고
    • The mechanism of Z alpha 1-antitrypsin accumulation in the liver
    • D.A. Lomas, D.L. Evans, J.T. Finch, and R.W. Carrell The mechanism of Z alpha 1-antitrypsin accumulation in the liver Nature 357 1992 605 607
    • (1992) Nature , vol.357 , pp. 605-607
    • Lomas, D.A.1    Evans, D.L.2    Finch, J.T.3    Carrell, R.W.4
  • 23
    • 84876803937 scopus 로고    scopus 로고
    • Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency
    • A. Ordóñez, E.L. Snapp, L. Tan, E. Miranda, S.J. Marciniak, and D.A. Lomas Endoplasmic reticulum polymers impair luminal protein mobility and sensitize to cellular stress in alpha1-antitrypsin deficiency Hepatology 57 2013 2049 2060
    • (2013) Hepatology , vol.57 , pp. 2049-2060
    • Ordóñez, A.1    Snapp, E.L.2    Tan, L.3    Miranda, E.4    Marciniak, S.J.5    Lomas, D.A.6
  • 24
    • 0029001576 scopus 로고
    • A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B
    • H.L. Pahl, and P.A. Baeuerle A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B EMBO J. 14 1995 2580 2588
    • (1995) EMBO J. , vol.14 , pp. 2580-2588
    • Pahl, H.L.1    Baeuerle, P.A.2
  • 25
    • 67651154714 scopus 로고    scopus 로고
    • Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase i modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency
    • S. Pan, L. Huang, J. McPherson, D. Muzny, F. Rouhani, M. Brantly, R. Gibbs, and R.N. Sifers Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency Hepatology 50 2009 275 281
    • (2009) Hepatology , vol.50 , pp. 275-281
    • Pan, S.1    Huang, L.2    McPherson, J.3    Muzny, D.4    Rouhani, F.5    Brantly, M.6    Gibbs, R.7    Sifers, R.N.8
  • 27
    • 0024463472 scopus 로고
    • The alpha 1-antitrypsin gene and emphysema
    • D.H. Perlmutter, and J.A. Pierce The alpha 1-antitrypsin gene and emphysema Am. J. Physiol. 257 1989 L147 L162
    • (1989) Am. J. Physiol. , vol.257 , pp. L147-L162
    • Perlmutter, D.H.1    Pierce, J.A.2
  • 28
    • 34248642305 scopus 로고    scopus 로고
    • Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: A meeting review
    • D.H. Perlmutter, J.L. Brodsky, W.F. Balistreri, and B.C. Trapnell Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review Hepatology 45 2007 1313 1323
    • (2007) Hepatology , vol.45 , pp. 1313-1323
    • Perlmutter, D.H.1    Brodsky, J.L.2    Balistreri, W.F.3    Trapnell, B.C.4
  • 34
    • 77958082207 scopus 로고    scopus 로고
    • Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette
    • A. Somers, J.-C. Jean, C.A. Sommer, A. Omari, C.C. Ford, J.A. Mills, L. Ying, A.G. Sommer, J.M. Jean, and B.W. Smith Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette Stem Cells 28 2010 1728 1740
    • (2010) Stem Cells , vol.28 , pp. 1728-1740
    • Somers, A.1    Jean, J.-C.2    Sommer, C.A.3    Omari, A.4    Ford, C.C.5    Mills, J.A.6    Ying, L.7    Sommer, A.G.8    Jean, J.M.9    Smith, B.W.10
  • 37
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 38
    • 0033671965 scopus 로고    scopus 로고
    • Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response
    • J.H. Teckman, and D.H. Perlmutter Retention of mutant alpha(1)-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response Am. J. Physiol. Gastrointest. Liver Physiol. 279 2000 G961 G974
    • (2000) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.279 , pp. G961-G974
    • Teckman, J.H.1    Perlmutter, D.H.2
  • 44
    • 0028593988 scopus 로고
    • A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency
    • Y. Wu, I. Whitman, E. Molmenti, K. Moore, P. Hippenmeyer, and D.H. Perlmutter A lag in intracellular degradation of mutant alpha 1-antitrypsin correlates with the liver disease phenotype in homozygous PiZZ alpha 1-antitrypsin deficiency Proc. Natl. Acad. Sci. USA 91 1994 9014 9018
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9014-9018
    • Wu, Y.1    Whitman, I.2    Molmenti, E.3    Moore, K.4    Hippenmeyer, P.5    Perlmutter, D.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.