Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes

Journal of Clinical Investigation

Volumn 121, Issue 6, 2011, Pages 2313-2325

  Christodoulou, Constantina ^a   Longmire, Tyler A ^a   Shen, Steven S ^a   Bourdon, Alice ^b   Sommer, Cesar A ^a   Gadue, Paul ^c   Spira, Avrum ^a   Gouon Evans, Valerie ^b   Murphy, George J ^a   Mostoslavsky, Gustavo ^a   Kotton, Darrell N ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3BETA; THYROTROPIN RECEPTOR; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PAX8; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX7; TRANSCRIPTOME;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; CPG ISLAND; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENDODERM; GENE EXPRESSION; GENE SILENCING; GENETIC VARIABILITY; GENOME IMPRINTING; GENOTYPE; IN VITRO STUDY; IN VIVO STUDY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; TRANSCRIPTION REGULATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL SEPARATION; CHIMERA; CHROMOSOME MAPPING; CLONE CELLS; DNA METHYLATION; EMBRYONIC STEM CELLS; ENDODERM; FETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; GENOMIC IMPRINTING; INDUCED PLURIPOTENT STEM CELLS; LIVER; MICE; MICE, SCID; MULTIPOTENT STEM CELLS; NEOPLASM TRANSPLANTATION; TERATOMA; TRANSCRIPTION FACTORS;

EID: 79957926957     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI43853     Document Type: Article

References (40)

1. Serls AE, Doherty S, Parvatiyar P, Wells JM, Deutsch GH. Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung. Development. 2005;132(1):35-47. (Pubitemid 40207965)
2. Cardoso WV, Kotton DN. Specification and patterning of the respiratory system. In: StemBook. Cambridge, Massachusetts, USA: Harvard Stem Cell Institute; 2008.
3. Jung J, Zheng M, Goldfarb M, Zaret KS. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science. 1999;284(5422):1998-2003. (Pubitemid 29309449)
4. Wells JM, Melton DA. Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development. 2000;127(8):1563-1572. (Pubitemid 30234914)
5. Gadue P, Huber TL, Nostro MC, Kattman S, Keller GM. Germ layer induction from embryonic stem cells. Exp Hematol. 2005;33(9):955-964. (Pubitemid 41225418)
6. Kubo A, et al. Development of definitive endoderm from embryonic stem cells in culture. Development. 2004;131(7):1651-1662. (Pubitemid 38559291)
7. Takahashi K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131(5):861-872. (Pubitemid 350138099)
8. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126(4):663-676. (Pubitemid 44233629)
9. Si-Tayeb K, et al. Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology. 2010;51(1):297-305.
10. Park IH, et al. Disease-specific induced pluripotent stem cells. Cell. 2008;134(5):877-886.
11. Somers A, et al. Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette. Stem Cells. 2010;28(10):1728-1740.
12. Maherali N, et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell. 2007;1(1):55-70.
13. Gadue P, Huber TL, Paddison PJ, Keller GM. Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc Natl Acad Sci U S A. 2006;103(45):16806-16811. (Pubitemid 44737334)
14. Gouon-Evans V, et al. BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm. Nat Biotechnol. 2006; 24(11):1402-1411. (Pubitemid 44722104)
15. Polo JM, et al. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol. 2010;28(8):848-855.
16. Chin MH, et al. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009;5(1):111-123.
17. Marchetto MC, Yeo GW, Kainohana O, Marsala M, Gage FH, Muotri AR. Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One. 2009;4(9):e7076.
18. Wilson KD, Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, Wu JC. MicroRNA profiling of human-induced pluripotent stem cells. Stem Cells Dev. 2009;18(5):749-758.
19. Hu BY, et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A. 2010;107(9):4335-4340.
20. Stadtfeld M, et al. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature. 2010;465(7295):175-181.
21. Kim K, et al. Epigenetic memory in induced pluripotent stem cells. Nature. 2010;467(7313):285-290.
22. D'Amour KA, Agulnick AD, Eliazer S, Kelly OG, Kroon E, Baetge EE. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol. 2005;23(12):1534-1541. (Pubitemid 41752931)
23. Spence JR, et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature. 2011;470(7332):105-109.
24. Maehr R, et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A. 2009;106(37):15768-15773.
25. Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells. 2009;27(3):543-549.
26. Stadtfeld M, Maherali N, Breault DT, Hochedlinger K. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell. 2008;2(3):230-240.
27. Sommer CA, et al. Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells. 2010;28(1):64-74.
28. Gadue P, et al. Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm. Stem Cells. 2009;27(9):2103-2113.
29. D'Amour KA, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol. 2006; 24(11):1392-1401. (Pubitemid 44722103)
30. Hagan JP, O'Neill BL, Stewart CL, Kozlov SV, Croce CM. At least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1. PLoS One. 2009;4(2):e4352.
31. da Rocha ST, Edwards CA, Ito M, Ogata T, Ferguson-Smith AC. Genomic imprinting at the mammalian Dlk1-Dio3 domain. Trends Genet. 2008;24(6):306-316.
32. Takahashi N, et al. Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice. Hum Mol Genet. 2009;18(10):1879-1888.
33. da Rocha ST, Tevendale M, Knowles E, Takada S, Watkins M, Ferguson-Smith AC. Restricted coexpression of Dlk1 and the reciprocally imprinted non-coding RNA, Gtl2: implications for cis-acting control. Dev Biol. 2007;306(2):810-823. (Pubitemid 46873526)
34. Tanimizu N, Nishikawa M, Saito H, Tsujimura T, Miyajima A. Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J Cell Sci. 2003; 116(pt 9):1775-1786. (Pubitemid 36582164)
35. Wu Q, Kawahara M, Kono T. Synergistic role of Igf2 and Dlk1 in fetal liver development and hematopoiesis in bi-maternal mice. J Reprod Dev. 2008;54(3):177-182. (Pubitemid 351918069)
36. Ang SL, et al. The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development. 1993;119(4):1301-1315.
37. Zaret KS, Watts J, Xu J, Wandzioch E, Smale ST, Sekiya T. Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb Symp Quant Biol. 2008;73:119-126.
38. Liu L, et al. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J Biol Chem. 2010;285(25):19483- 19490.
39. Tevendale M, Watkins M, Rasberry C, Cattanach B, Ferguson-Smith AC. Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting. Cytogenet Genome Res. 2006;113(1-4):215- 222.
40. Lengner CJ, et al. Oct4 expression is not required for mouse somatic stem cell self-renewal. Cell Stem Cell. 2007;1(4):403-415. (Pubitemid 47506536)