-
1
-
-
84878864199
-
The hallmarks of aging
-
(Review)
-
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell 2013; 153: 1194-217. (Review)
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
López-Otín, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
2
-
-
67650439330
-
Caloric restriction delays disease onset and mortality in rhesus monkeys
-
Colman RJ, Anderson RM, Johnson SC, et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science 2009; 325: 201-4.
-
(2009)
Science
, vol.325
, pp. 201-204
-
-
Colman, R.J.1
Erson, R.M.2
Johnson, S.C.3
-
3
-
-
36048991085
-
Physiology. An integrative view of obesity
-
Wisse BE, Kim F, Schwartz MW. Physiology. An integrative view of obesity. Science 2007; 318: 928-9.
-
(2007)
Science
, vol.318
, pp. 928-929
-
-
Wisse, B.E.1
Kim, F.2
Schwartz, M.W.3
-
4
-
-
33645523067
-
Prevalence of overweight and obesity in the united states, 1999-2004
-
Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the united states, 1999-2004. JAMA 2006; 295: 1549-55.
-
(2006)
JAMA
, vol.295
, pp. 1549-1555
-
-
Ogden, C.L.1
Carroll, M.D.2
Curtin, L.R.3
McDowell, M.A.4
Tabak, C.J.5
Flegal, K.M.6
-
5
-
-
84859089427
-
Lifestyle change and mobility in obese adults with type 2 diabetes
-
Rejeski WJ, Ip EH, Bertoni AG, et al. Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med 2012; 366: 1209-17.
-
(2012)
N Engl J Med
, vol.366
, pp. 1209-1217
-
-
Rejeski, W.J.1
Ip, E.H.2
Bertoni, A.G.3
-
6
-
-
78649747039
-
Body-mass index and mortality among 1.46 million white adults
-
Berrington de Gonzalez A, Hartge P, Cerhan JR, et al. Body-mass index and mortality among 1.46 million white adults. N Engl J Med 2010; 363: 2211-9.
-
(2010)
N Engl J Med
, vol.363
, pp. 2211-2219
-
-
De Berrington Gonzalez, A.1
Hartge, P.2
Cerhan, J.R.3
-
7
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
(Review)
-
Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006; 444: 875-80. (Review)
-
(2006)
Nature
, vol.444
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
8
-
-
81455135755
-
Childhood adiposity, adult adiposity, and cardiovascular risk factors
-
Juonala M, Magnussen CG, Berenson GS, et al. Childhood adiposity, adult adiposity, and cardiovascular risk factors. N Engl J Med 2011; 365: 1876-85.
-
(2011)
N Engl J Med
, vol.365
, pp. 1876-1885
-
-
Juonala, M.1
Magnussen, C.G.2
Berenson, G.S.3
-
9
-
-
68349150756
-
CD8+ effector t cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector t cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15: 914-20.
-
(2009)
Nat Med
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
-
10
-
-
51349156218
-
Insulin sensitivity: Modulation by nutrients and inflammation
-
(Review)
-
Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 2008; 118: 2992-3002. (Review)
-
(2008)
J Clin Invest
, vol.118
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
11
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 1993; 259: 87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
12
-
-
84874603171
-
Cellular senescence and the senescent secretory phenotype: Therapeutic opportunities
-
(Review)
-
Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J Clin Invest 2013; 123: 966-72. (Review)
-
(2013)
J Clin Invest
, vol.123
, pp. 966-972
-
-
Tchkonia, T.1
Zhu, Y.2
Van Deursen, J.3
Campisi, J.4
Kirkland, J.L.5
-
13
-
-
68249096784
-
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
-
Rodier F, Coppé JP, Patil CK, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol 2009; 11: 973-9.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 973-979
-
-
Rodier, F.1
Coppé, J.P.2
Patil, C.K.3
-
14
-
-
33947520124
-
P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
-
Sano M, Minamino T, Toko H, et al. P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature 2007; 446: 444-8.
-
(2007)
Nature
, vol.446
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
-
15
-
-
84855453214
-
P53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure
-
Shimizu I, Yoshida Y, Katsuno T, et al. p53-induced adipose tissue inflammation is critically involved in the development of insulin resistance in heart failure. Cell Metab 2012; 15: 51-64.
-
(2012)
Cell Metab
, vol.15
, pp. 51-64
-
-
Shimizu, I.1
Yoshida, Y.2
Katsuno, T.3
-
16
-
-
77951773194
-
Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents
-
Shimizu I, Minamino T, Toko H, et al. Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents. J Clin Invest 2010; 120: 1506-14.
-
(2010)
J Clin Invest
, vol.120
, pp. 1506-1514
-
-
Shimizu, I.1
Minamino, T.2
Toko, H.3
-
17
-
-
0021322138
-
Thermogenic mechanisms in brown fat
-
(Review)
-
Nicholls DG, Locke RM. Thermogenic mechanisms in brown fat. Physiol Rev 1984; 64: 1-64. (Review)
-
(1984)
Physiol Rev
, vol.64
, pp. 1-64
-
-
Nicholls, D.G.1
Locke, R.M.2
-
19
-
-
67650215124
-
Brown fat in humans: Turning up the heat on obesity
-
Seale P, Lazar MA. Brown fat in humans: turning up the heat on obesity. Diabetes 2009; 58: 1482-4.
-
(2009)
Diabetes
, vol.58
, pp. 1482-1484
-
-
Seale, P.1
Lazar, M.A.2
-
20
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess AM, Lehman S, Williams G, et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med 2009; 360: 1509-17.
-
(2009)
N Engl J Med
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
-
21
-
-
77953169046
-
Cellular bioenergetics as a target for obesity therapy
-
(Review)
-
Tseng YH, Cypess AM, Kahn CR. Cellular bioenergetics as a target for obesity therapy. Nat Rev Drug Discov 2010; 9: 465-82. (Review)
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 465-482
-
-
Tseng, Y.H.1
Cypess, A.M.2
Kahn, C.R.3
-
22
-
-
0020608986
-
The thermogenic mechanism of brown adipose tissue. Review
-
Nicholls DG. The thermogenic mechanism of brown adipose tissue. Review. Biosci Rep 1983; 3: 431-41.
-
(1983)
Biosci Rep
, vol.3
, pp. 431-441
-
-
Nicholls, D.G.1
-
23
-
-
0030021071
-
Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia
-
Hamann A, Flier JS, Lowell BB. Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia. Endocrinology 1996; 137: 21-9.
-
(1996)
Endocrinology
, vol.137
, pp. 21-29
-
-
Hamann, A.1
Flier, J.S.2
Lowell, B.B.3
-
24
-
-
34547631960
-
Unexpected evidence for active brown adipose tissue in adult humans
-
(Review)
-
Nedergaard J, Bengtsson T, Cannon B. Unexpected evidence for active brown adipose tissue in adult humans. Am J Physiol Endocrinol Metab 2007; 293: E444-52. (Review)
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, pp. E444-E452
-
-
Nedergaard, J.1
Bengtsson, T.2
Cannon, B.3
-
25
-
-
77950221998
-
Human brown adipose tissue
-
(Review)
-
Enerbäck S. Human brown adipose tissue. Cell Metab 2010; 11: 248-52. (Review)
-
(2010)
Cell Metab
, vol.11
, pp. 248-252
-
-
Enerbäck, S.1
-
26
-
-
79751503329
-
Brown adipose tissue activity controls triglyceride clearance
-
Bartelt A, Bruns OT, Reimer R, et al. Brown adipose tissue activity controls triglyceride clearance. Nat Med 2010; 17: 200-5.
-
(2010)
Nat Med
, vol.17
, pp. 200-205
-
-
Bartelt, A.1
Bruns, O.T.2
Reimer, R.3
-
27
-
-
77950237717
-
The changed metabolic world with human brown adipose tissue: Therapeutic visions
-
(Review)
-
Nedergaard J, Cannon B. The changed metabolic world with human brown adipose tissue: therapeutic visions. Cell Metab 2010; 11: 268-72. (Review)
-
(2010)
Cell Metab
, vol.11
, pp. 268-272
-
-
Nedergaard, J.1
Cannon, B.2
-
28
-
-
84873854027
-
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
-
Stanford KI, Middelbeek RJ, Townsend KL, et al. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. J Clin Invest 2013; 123: 215-23.
-
(2013)
J Clin Invest
, vol.123
, pp. 215-223
-
-
Stanford, K.I.1
Middelbeek, R.J.2
Townsend, K.L.3
-
29
-
-
84899755491
-
Vascular rarefaction mediates whitening of brown fat in obesity
-
Shimizu I, Aprahamian T, Kikuchi R, et al. Vascular rarefaction mediates whitening of brown fat in obesity. J Clin Invest 2014; 124: 2099-112.
-
(2014)
J Clin Invest
, vol.124
, pp. 2099-2112
-
-
Shimizu, I.1
Aprahamian, T.2
Kikuchi, R.3
-
30
-
-
0037007075
-
Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction
-
Minamino T, Miyauchi H, Yoshida T, Ishida Y, Yoshida H, Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation 2002; 105: 1541-4.
-
(2002)
Circulation
, vol.105
, pp. 1541-1544
-
-
Minamino, T.1
Miyauchi, H.2
Yoshida, T.3
Ishida, Y.4
Yoshida, H.5
Komuro, I.6
-
31
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A 1995; 92: 9363-7.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
-
32
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25: 585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
33
-
-
80855138775
-
Clearance of p16ink4apositive senescent cells delays ageing-associated disorders
-
Baker DJ, Wijshake T, Tchkonia T, et al. Clearance of p16ink4apositive senescent cells delays ageing-associated disorders. Nature 2011; 479: 232-6.
-
(2011)
Nature
, vol.479
, pp. 232-236
-
-
Baker, D.J.1
Wijshake, T.2
Tchkonia, T.3
-
34
-
-
69949150673
-
A crucial role for adipose tissue p53 in the regulation of insulin resistance
-
Minamino T, Orimo M, Shimizu I, et al. A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med 2009; 15: 1082-7.
-
(2009)
Nat Med
, vol.15
, pp. 1082-1087
-
-
Minamino, T.1
Orimo, M.2
Shimizu, I.3
-
35
-
-
84887430076
-
Metabolic regulation by p53 family members
-
(Review)
-
Berkers CR, Maddocks OD, Cheung EC, Mor I, Vousden KH. Metabolic regulation by p53 family members. Cell Metab 2013; 18: 617-33. (Review)
-
(2013)
Cell Metab
, vol.18
, pp. 617-633
-
-
Berkers, C.R.1
Maddocks, O.D.2
Cheung, E.C.3
Mor, I.4
Vousden, K.H.5
-
36
-
-
33947534030
-
Lane DP. P53 in health and disease
-
(Review)
-
Vousden KH, Lane DP. p53 in health and disease. Nat Rev Mol Cell Biol 2007; 8: 275-83. (Review)
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 275-283
-
-
Vousden, K.H.1
-
37
-
-
1042266548
-
Modulation of mammalian life span by the short isoform of p53
-
Maier B, Gluba W, Bernier B, et al. Modulation of mammalian life span by the short isoform of p53. Genes Dev 2004; 18: 306-19.
-
(2004)
Genes Dev
, vol.18
, pp. 306-319
-
-
Maier, B.1
Gluba, W.2
Bernier, B.3
-
38
-
-
0037011958
-
P53 mutant mice that display early ageing-associated phenotypes
-
Tyner SD, Venkatachalam S, Choi J, et al. p53 mutant mice that display early ageing-associated phenotypes. Nature 2002; 415: 45-53.
-
(2002)
Nature
, vol.415
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
-
39
-
-
45549108907
-
P53 and its role in the development of heart failure
-
(Review, Japanese)
-
Sano M, Komuro I. p53 and its role in the development of heart failure. Nihon Rinsho 2008; 66: 1013-21. (Review, Japanese)
-
(2008)
Nihon Rinsho
, vol.66
, pp. 1013-1021
-
-
Sano, M.1
Komuro, I.2
-
40
-
-
33846121333
-
Vascular cell senescence: Contribution to atherosclerosis
-
(Review)
-
Minamino T, Komuro I. Vascular cell senescence: contribution to atherosclerosis. Circ Res 2007; 100: 15-26. (Review)
-
(2007)
Circ Res
, vol.100
, pp. 15-26
-
-
Minamino, T.1
Komuro, I.2
-
42
-
-
47949094965
-
Integration of metabolism and inflammation by lipid-activated nuclear receptors
-
(Review)
-
Bensinger SJ, Tontonoz P. Integration of metabolism and inflammation by lipid-activated nuclear receptors. Nature 2008; 454: 470-7. (Review)
-
(2008)
Nature
, vol.454
, pp. 470-477
-
-
Bensinger, S.J.1
Tontonoz, P.2
-
43
-
-
44349112305
-
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
-
Kang K, Reilly SM, Karabacak V, et al. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab 2008; 7: 485-95.
-
(2008)
Cell Metab
, vol.7
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
-
44
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112: 1796-808.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
45
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003; 112: 1821-30.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
-
46
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda H, Tateya S, Tamori Y, et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006; 116: 1494-505.
-
(2006)
J Clin Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
-
47
-
-
84885108889
-
Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity
-
Shimizu I, Yoshida Y, Moriya J, et al. Semaphorin3E-induced inflammation contributes to insulin resistance in dietary obesity. Cell Metab 2013; 18: 491-504.
-
(2013)
Cell Metab
, vol.18
, pp. 491-504
-
-
Shimizu, I.1
Yoshida, Y.2
Moriya, J.3
-
48
-
-
84856529575
-
Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans
-
Ouellet V, Labbé SM, Blondin DP, et al. Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. J Clin Invest 2012; 122: 545-52.
-
(2012)
J Clin Invest
, vol.122
, pp. 545-552
-
-
Ouellet, V.1
Labbé, S.M.2
Blondin, D.P.3
-
49
-
-
84881260642
-
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
-
van der Lans AA, Hoeks J, Brans B, et al. Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest 2013; 123: 3395-403.
-
(2013)
J Clin Invest
, vol.123
, pp. 3395-3403
-
-
Van Der Lans, A.A.1
Hoeks, J.2
Brans, B.3
-
50
-
-
0023128367
-
Streptozotocin diabetes in rats after acclimation to cold environment
-
Takano T, Honma T, Motohashi Y, Kobayashi Y. Streptozotocin diabetes in rats after acclimation to cold environment. Prev Med 1987; 16: 63-9.
-
(1987)
Prev Med
, vol.16
, pp. 63-69
-
-
Takano, T.1
Honma, T.2
Motohashi, Y.3
Kobayashi, Y.4
-
51
-
-
84881221754
-
Recruited brown adipose tissue as an antiobesity agent in humans
-
Yoneshiro T, Aita S, Matsushita M, et al. Recruited brown adipose tissue as an antiobesity agent in humans. J Clin Invest 2013; 123: 3404-8.
-
(2013)
J Clin Invest
, vol.123
, pp. 3404-3408
-
-
Yoneshiro, T.1
Aita, S.2
Matsushita, M.3
-
52
-
-
3042786130
-
Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice
-
Bråkenhielm E, Cao R, Gao B, et al. Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice. Circ Res 2004; 94: 1579-88.
-
(2004)
Circ Res
, vol.94
, pp. 1579-1588
-
-
Bråkenhielm, E.1
Cao, R.2
Gao, B.3
-
54
-
-
84872158534
-
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis
-
Sung HK, Doh KO, Son JE, et al. Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis. Cell Metab 2013; 17: 61-72.
-
(2013)
Cell Metab
, vol.17
, pp. 61-72
-
-
Sung, H.K.1
Doh, K.O.2
Son, J.E.3
-
55
-
-
84863198909
-
Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance
-
Elias I, Franckhauser S, Ferré T, et al. Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance. Diabetes 2012; 61: 1801-13.
-
(2012)
Diabetes
, vol.61
, pp. 1801-1813
-
-
Elias, I.1
Franckhauser, S.2
Ferré, T.3
-
56
-
-
2942703809
-
Reversal of obesity by targeted ablation of adipose tissue
-
Kolonin MG, Saha PK, Chan L, Pasqualini R, Arap W. Reversal of obesity by targeted ablation of adipose tissue. Nat Med 2004; 10: 625-32.
-
(2004)
Nat Med
, vol.10
, pp. 625-632
-
-
Kolonin, M.G.1
Saha, P.K.2
Chan, L.3
Pasqualini, R.4
Arap, W.5
-
57
-
-
0036678477
-
Adipose tissue mass can be regulated through the vasculature
-
Rupnick MA, Panigrahy D, Zhang CY, et al. Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci U S A 2002; 99: 10730-5.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10730-10735
-
-
Rupnick, M.A.1
Panigrahy, D.2
Zhang, C.Y.3
-
58
-
-
1442354888
-
Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
-
Bråkenhielm E, Veitonmäki N, Cao R, et al. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A 2004; 101: 2476-81.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2476-2481
-
-
Bråkenhielm, E.1
Veitonmäki, N.2
Cao, R.3
-
59
-
-
0030766192
-
Apoptosis in the failing human heart
-
Olivetti G, Abbi R, Quaini F, et al. Apoptosis in the failing human heart. N Engl J Med 1997; 336: 1131-41.
-
(1997)
N Engl J Med
, vol.336
, pp. 1131-1141
-
-
Olivetti, G.1
Abbi, R.2
Quaini, F.3
-
60
-
-
0035846652
-
8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts
-
Tsutsui H, Ide T, Shiomi T, et al. 8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts. Circulation 2001; 104: 2883-5.
-
(2001)
Circulation
, vol.104
, pp. 2883-2885
-
-
Tsutsui, H.1
Ide, T.2
Shiomi, T.3
-
61
-
-
84883562084
-
Cardiac metabolism in heart failure: Implications beyond atp production
-
(Review)
-
Doenst T, Nguyen TD, Abel ED. Cardiac metabolism in heart failure: Implications beyond atp production. Circ Res 2013; 113: 709-24. (Review)
-
(2013)
Circ Res
, vol.113
, pp. 709-724
-
-
Doenst, T.1
Nguyen, T.D.2
Abel, E.D.3
-
62
-
-
33947239659
-
The failing heart--an engine out of fuel
-
(Review)
-
Neubauer S. The failing heart--an engine out of fuel. N Engl J Med 2007; 356: 1140-51. (Review)
-
(2007)
N Engl J Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
63
-
-
3242816108
-
Insulin resistance in idiopathic dilated cardiomyopathy: A possible etiologic link
-
Witteles RM, Tang WH, Jamali AH, Chu JW, Reaven GM, Fowler MB. Insulin resistance in idiopathic dilated cardiomyopathy: a possible etiologic link. J Am Coll Cardiol 2004; 44: 78-81.
-
(2004)
J am Coll Cardiol
, vol.44
, pp. 78-81
-
-
Witteles, R.M.1
Tang, W.H.2
Jamali, A.H.3
Chu, J.W.4
Reaven, G.M.5
Fowler, M.B.6
-
64
-
-
0030751957
-
Insulin resistance in chronic heart failure: Relation to severity and etiology of heart failure
-
Swan JW, Anker SD, Walton C, et al. Insulin resistance in chronic heart failure: relation to severity and etiology of heart failure. J Am Coll Cardiol 1997; 30: 527-32.
-
(1997)
J am Coll Cardiol
, vol.30
, pp. 527-532
-
-
Swan, J.W.1
Anker, S.D.2
Walton, C.3
-
65
-
-
0034812816
-
Several factors associated with the insulin resistance syndrome are predictors of left ventricular systolic dysfunction in a male population after 20 years of follow-up
-
Arnlöv J, Lind L, Zethelius B, et al. Several factors associated with the insulin resistance syndrome are predictors of left ventricular systolic dysfunction in a male population after 20 years of follow-up. Am Heart J 2001; 142: 720-4.
-
(2001)
Am Heart J
, vol.142
, pp. 720-724
-
-
Arnlöv, J.1
Lind, L.2
Zethelius, B.3
-
66
-
-
34547590901
-
Metabolic mechanisms in heart failure
-
(Review)
-
Ashrafian H, Frenneaux MP, Opie LH. Metabolic mechanisms in heart failure. Circulation 2007; 116: 434-48. (Review)
-
(2007)
Circulation
, vol.116
, pp. 434-448
-
-
Ashrafian, H.1
Frenneaux, M.P.2
Opie, L.H.3
-
67
-
-
34547961920
-
Cardiac energy metabolism in obesity
-
(Review)
-
Lopaschuk GD, Folmes CD, Stanley WC. Cardiac energy metabolism in obesity. Circ Res 2007; 101: 335-47. (Review)
-
(2007)
Circ Res
, vol.101
, pp. 335-347
-
-
Lopaschuk, G.D.1
Folmes, C.D.2
Stanley, W.C.3
-
68
-
-
37849047917
-
Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options
-
(Review)
-
Witteles RM, Fowler MB. Insulin-resistant cardiomyopathy clinical evidence, mechanisms, and treatment options. J Am Coll Cardiol 2008; 51: 93-102. (Review)
-
(2008)
J am Coll Cardiol
, vol.51
, pp. 93-102
-
-
Witteles, R.M.1
Fowler, M.B.2
-
69
-
-
22244474634
-
Insulin resistance and risk of congestive heart failure
-
Ingelsson E, Sundström J, Arnlöv J, Zethelius B, Lind L. Insulin resistance and risk of congestive heart failure. JAMA 2005; 294: 334-41.
-
(2005)
JAMA
, vol.294
, pp. 334-341
-
-
Ingelsson, E.1
Sundström, J.2
Arnlöv, J.3
Zethelius, B.4
Lind, L.5
-
71
-
-
77951176737
-
Extending healthy life span--from yeast to humans
-
(Review)
-
Fontana L, Partridge L, Longo VD. Extending healthy life span--from yeast to humans. Science 2010; 328: 321-6. (Review)
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
72
-
-
0027771804
-
A C. Elegans mutant that lives twice as long as wild type
-
Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993; 366: 461-4.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
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