8-Oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts

Circulation

Volumn 104, Issue 24, 2001, Pages 2883-2885

  Tsutsui, Hiroyuki ^a   Ide, Tomomi ^a   Shiomi, Tetsuya ^a   Kang, Dongchon ^a   Hayashidani, Shunji ^a   Suematsu, Nobuhiro ^a   Wen, Jing ^a   Utsumi, Hideo ^b   Hamasaki, Naotaka ^a   Takeshita, Akira ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

DNA; Free radicals; Heart failure; Mitochondria

Indexed keywords

8 OXO 7,8 DIHYDRODEOXYGUANOSINE TRIPHOSPHATASE; DEOXYGUANOSINE PHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; REACTIVE OXYGEN METABOLITE; TEMPOL; THIOBARBITURIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MARKER; DNA DAMAGE; DNA REPLICATION; ECHOCARDIOGRAPHY; ELECTRON SPIN RESONANCE; HEART DILATATION; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE CONTRACTILITY; HEART MITOCHONDRION; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; LEFT CORONARY ARTERY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REGULATORY MECHANISM; WESTERN BLOTTING;

EID: 0035846652     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc4901.101347     Document Type: Article

References (12)

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6. Increased 8-oxo-dGTPase in the mitochondria of substantia nigral neurons in Parkinson's disease
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10. Mitochondrial genetics: A paradigm for aging and degenerative diseases?
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