-
1
-
-
17044411374
-
Mutator phenotype in cancer: Timing and perspectives
-
Bielas JH, Loeb LA (2005) Mutator phenotype in cancer: Timing and perspectives. Environ Mol Mutagen 45(2-3):206-213.
-
(2005)
Environ Mol Mutagen
, vol.45
, Issue.2-3
, pp. 206-213
-
-
Bielas, J.H.1
Loeb, L.A.2
-
2
-
-
2342419732
-
DNA replication fidelity
-
Kunkel TA (2004) DNA replication fidelity. J Biol Chem 279(17):16895-16898.
-
(2004)
J Biol Chem
, vol.279
, Issue.17
, pp. 16895-16898
-
-
Kunkel, T.A.1
-
3
-
-
84855267435
-
The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved
-
Miyabe I, Kunkel TA, Carr AM (2011) The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved. PLoS Genet 7(12):e1002407.
-
(2011)
PLoS Genet
, vol.7
, Issue.12
, pp. e1002407
-
-
Miyabe, I.1
Kunkel, T.A.2
Carr, A.M.3
-
4
-
-
42949119884
-
Division of labor at the eukaryotic replication fork
-
Nick McElhinny SA, Gordenin DA, Stith CM, Burgers PM, Kunkel TA (2008) Division of labor at the eukaryotic replication fork. Mol Cell 30(2):137-144.
-
(2008)
Mol Cell
, vol.30
, Issue.2
, pp. 137-144
-
-
Nick McElhinny, S.A.1
Gordenin, D.A.2
Stith, C.M.3
Burgers, P.M.4
Kunkel, T.A.5
-
5
-
-
53249147678
-
DNA polymerase epsilon: A polymerase of unusual size (and complexity)
-
Pursell ZF, Kunkel TA (2008) DNA polymerase epsilon: A polymerase of unusual size (and complexity). Prog Nucleic Acid Res Mol Biol 82:101-145.
-
(2008)
Prog Nucleic Acid Res Mol Biol
, vol.82
, pp. 101-145
-
-
Pursell, Z.F.1
Kunkel, T.A.2
-
6
-
-
84929167589
-
Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity
-
Mertz TM, Sharma S, Chabes A, Shcherbakova PV (2015) Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelity. Proc Natl Acad Sci USA 112:E2467-E2476.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E2467-E2476
-
-
Mertz, T.M.1
Sharma, S.2
Chabes, A.3
Shcherbakova, P.V.4
-
7
-
-
84929224147
-
dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants
-
Williams LN, et al. (2015) dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants. Proc Natl Acad Sci USA 112:E2457-E2466.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E2457-E2466
-
-
Williams, L.N.1
-
8
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb LA (1991) Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51(12):3075-3079.
-
(1991)
Cancer Res
, vol.51
, Issue.12
, pp. 3075-3079
-
-
Loeb, L.A.1
-
9
-
-
0028019398
-
Microsatellite instability: Marker of a mutator phenotype in cancer
-
Loeb LA (1994) Microsatellite instability: Marker of a mutator phenotype in cancer. Cancer Res 54(19):5059-5063.
-
(1994)
Cancer Res
, vol.54
, Issue.19
, pp. 5059-5063
-
-
Loeb, L.A.1
-
10
-
-
0035057806
-
BRCA1 and BRCA2 and the genetics of breast and ovarian cancer
-
Welcsh PL, King MC (2001) BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum Mol Genet 10(7):705-713.
-
(2001)
Hum Mol Genet
, vol.10
, Issue.7
, pp. 705-713
-
-
Welcsh, P.L.1
King, M.C.2
-
11
-
-
0034264387
-
Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer
-
Takama F, et al. (2000) Mutation analysis of the hMTH1 gene in sporadic human ovarian cancer. Int J Oncol 17(3):467-471.
-
(2000)
Int J Oncol
, vol.17
, Issue.3
, pp. 467-471
-
-
Takama, F.1
-
12
-
-
84870657711
-
A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation
-
Yamtich J, Nemec AA, Keh A, Sweasy JB (2012) A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation. PLoS Genet 8(11):e1003052.
-
(2012)
PLoS Genet
, vol.8
, Issue.11
, pp. e1003052
-
-
Yamtich, J.1
Nemec, A.A.2
Keh, A.3
Sweasy, J.B.4
-
13
-
-
0029837248
-
Mismatch repair defects in human carcinogenesis
-
Eshleman JR, Markowitz SD (1996) Mismatch repair defects in human carcinogenesis. Hum Mol Genet 5(Spec No):1489-1494.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1489-1494
-
-
Eshleman, J.R.1
Markowitz, S.D.2
-
14
-
-
84876442276
-
Emergence of DNA polymerase e antimutators that escape error-induced extinction in yeast
-
Williams LN, Herr AJ, Preston BD (2013) Emergence of DNA polymerase e antimutators that escape error-induced extinction in yeast. Genetics 193(3):751-770.
-
(2013)
Genetics
, vol.193
, Issue.3
, pp. 751-770
-
-
Williams, L.N.1
Herr, A.J.2
Preston, B.D.3
-
15
-
-
0033559182
-
Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines
-
Flohr T, et al. (1999) Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines. Int J Cancer 80(6):919-929.
-
(1999)
Int J Cancer
, vol.80
, Issue.6
, pp. 919-929
-
-
Flohr, T.1
-
16
-
-
76349101664
-
A cancerassociated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability
-
Daee DL, Mertz TM, Shcherbakova PV (2010) A cancerassociated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability. Proc Natl Acad Sci USA 107(1):157-162.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.1
, pp. 157-162
-
-
Daee, D.L.1
Mertz, T.M.2
Shcherbakova, P.V.3
-
17
-
-
84880861468
-
The exomes of the NCI-60 panel: A genomic resource for cancer biology and systems pharmacology
-
Abaan OD, et al. (2013) The exomes of the NCI-60 panel: A genomic resource for cancer biology and systems pharmacology. Cancer Res 73(14):4372-4382.
-
(2013)
Cancer Res
, vol.73
, Issue.14
, pp. 4372-4382
-
-
Abaan, O.D.1
-
18
-
-
84892431829
-
Checkpoint kinases regulate a global network of transcription factors in response to DNA damage
-
Jaehnig EJ, Kuo D, Hombauer H, Ideker TG, Kolodner RD (2013) Checkpoint kinases regulate a global network of transcription factors in response to DNA damage. Cell Reports 4(1):174-188.
-
(2013)
Cell Reports
, vol.4
, Issue.1
, pp. 174-188
-
-
Jaehnig, E.J.1
Kuo, D.2
Hombauer, H.3
Ideker, T.G.4
Kolodner, R.D.5
-
19
-
-
33746539166
-
DNA precursor metabolism and genomic stability
-
Mathews CK (2006) DNA precursor metabolism and genomic stability. FASEB J 20(9):1300-1314.
-
(2006)
FASEB J
, vol.20
, Issue.9
, pp. 1300-1314
-
-
Mathews, C.K.1
-
20
-
-
33646359442
-
Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells
-
Håkansson P, Hofer A, Thelander L (2006) Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells. J Biol Chem 281(12):7834-7841.
-
(2006)
J Biol Chem
, vol.281
, Issue.12
, pp. 7834-7841
-
-
Håkansson, P.1
Hofer, A.2
Thelander, L.3
-
21
-
-
0037423223
-
Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase
-
Chabes A, et al. (2003) Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase. Cell 112(3):391-401.
-
(2003)
Cell
, vol.112
, Issue.3
, pp. 391-401
-
-
Chabes, A.1
-
22
-
-
79952320889
-
Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools
-
Kumar D, et al. (2011) Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools. Nucleic Acids Res 39(4):1360-1371.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.4
, pp. 1360-1371
-
-
Kumar, D.1
-
23
-
-
82755165376
-
Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli
-
Gon S, Napolitano R, Rocha W, Coulon S, Fuchs RP (2011) Increase in dNTP pool size during the DNA damage response plays a key role in spontaneous and induced-mutagenesis in Escherichia coli. Proc Natl Acad Sci USA 108(48):19311-19316.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.48
, pp. 19311-19316
-
-
Gon, S.1
Napolitano, R.2
Rocha, W.3
Coulon, S.4
Fuchs, R.P.5
-
24
-
-
0015499993
-
Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3′ leads to 5′ exonuclease activity in deoxyribonucleic acid polymerases
-
Brutlag D, Kornberg A (1972) Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3′ leads to 5′ exonuclease activity in deoxyribonucleic acid polymerases. J Biol Chem 247(1):241-248.
-
(1972)
J Biol Chem
, vol.247
, Issue.1
, pp. 241-248
-
-
Brutlag, D.1
Kornberg, A.2
-
25
-
-
84941097040
-
Switching between polymerase and exonuclease sites in DNA polymerase ε
-
Ganai RA, Bylund GO, Johansson E (2015) Switching between polymerase and exonuclease sites in DNA polymerase ε. Nucleic Acids Res 43(2):932-942.
-
(2015)
Nucleic Acids Res
, vol.43
, Issue.2
, pp. 932-942
-
-
Ganai, R.A.1
Bylund, G.O.2
Johansson, E.3
|