Systematic optimization of human pluripotent stem cells media using Design of Experiments

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Marinho, Paulo A ^a   Chailangkarn, Thanathom ^a   Muotri, Alysson R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONDITIONED MEDIUM; FIBROBLAST GROWTH FACTOR 2; NEU DIFFERENTIATION FACTOR; NRG1 PROTEIN, HUMAN;

ALGORITHM; BATCH CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CHEMISTRY; CONDITIONED MEDIUM; CYTOLOGY; HUMAN; METABOLISM; METHODOLOGY; PHYSIOLOGY; PLURIPOTENT STEM CELL; PROCEDURES; STATISTICAL MODEL;

ALGORITHMS; BATCH CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CULTURE MEDIA, CONDITIONED; FIBROBLAST GROWTH FACTOR 2; HUMANS; MODELS, STATISTICAL; NEUREGULIN-1; PLURIPOTENT STEM CELLS; RESEARCH DESIGN;

EID: 84929180189     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep09834     Document Type: Article

References (54)

1. Ludwig, T. E. et al. Derivation of human embryonic stem cells in defined conditions. Nat Biotechnol. 24, 185-187 (2006).
2. Trounson, A. The production and directed differentiation of human embryonic stem cells. Endocr. Rev. 27, 208-219 (2006).
3. Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
4. Han, S. S., Williams, L. A. & Eggan, K. C. Constructing and deconstructing stem cell models of neurological disease. Neuron 70, 626-644 (2011).
5. Shi, Y., Kirwan, P. & Livesey, F. J. Directed differentiation of human pluripotent stem cells to cerebral cortex neurons and neural networks. Nat. Protoc. 7, 1836-1846 (2012).
6. Kinney, M. A., Sargent, C. Y. & McDevitt, T. C. The multiparametric effects of hydrodynamic environments on stem cell culture. Tissue. Eng. Part. B. Rev. 17, 249-262 (2011).
7. Lundstedt, T. et al. Experimental design and optimization. Chemometr. Intell. Lab. 42, 3-40 (1998).
8. Montgomery, D. C. Design and analysis of experiments. (John Wiley & Sons, 2008).
9. Thielman, J. & Ge, P. Applying axiomatic design theory to the evaluation and optimization of large-scale engineering systems. J. Eng. Design. 17, 1-16 (2006).
10. Ariffin, M. K. A. M., Ali, M. I. M., Sapuan, S. M. & Ismail, N. An optimise drilling process for an aircraft composite structure using design of experiments. Sci. Res. Essays 4, 1109-1116 (2009).
11. Modirzadeh, M., Tesfamariam, S. & Milani, A. S. Performance based earthquake evaluation of reinforced concrete buildings using design of experiments. Expert. Syst. Appl. 39, 2919-2926 (2012).
12. Singh, B., Kumar, R. & Ahuja, N. Optimizing drug delivery systems using systematic "design of experiments." Part I: fundamental aspects. Crit. Rev. Ther. Drug. Carrier. Syst. 22, 27-105 (2005).
13. Martinello, T., Kaneko, T. M., Velasco, M. V. R., Taqueda, M. E. S. & Consiglieri, V. O. Optimization of poorly compactable drug tablets manufactured by direct compression using the mixture experimental design. International Journal of Pharmaceutics 322, 87-95 (2006).
14. Xu, R. H. et al. Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat. Methods 2, 185-190 (2005).
15. Wang, L. et al. Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling. Blood 110, 4111-4119 (2007).
16. Muotri, A., Marinho, P. A. N., Rehen, S. K., Dos Reis Castilho, L., inventors; The Regents of The University of California Office of The President, assignee. Stem cell defined media for xeno-free and feeder free conditions and uses thereof. World Patent WO 2011/140397 A2. 2011 Nov 10. English.
17. Marchetto, M. C. et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 143, 527-539 (2010).
18. Mesri, M. et al. Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting. The American journal of pathology 158, 1757-1765 (2001).
19. Dornan, D. et al. The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature 429, 86-92 (2004).
20. Watanabe, K. et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotechnol. 25, 681-686 (2007).
21. Hartung, O., Huo, H., Daley, G. Q. & Schlaeger, T. M. Clump passaging and expansion of human embryonic and induced pluripotent stem cells on mouse embryonic fibroblast feeder cells. Curr. Protoc. Stem. Cell. Biol. Chapter 1, Unit 1C 10 (2010).
22. Fluri, D. A. et al. Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures. Nat. Methods. 9, 509-516 (2012).
23. Bruck, T. & Benvenisty, N. Meta-Analysis of the heterogeneity of X chromosome inactivation in human pluripotent stem cells. Stem. Cell. Res. 6, 187-193 (2011).
24. Mekhoubad, S. et al. Erosion of dosage compensation impacts human iPSC disease modeling. Cell Stem Cell 10, 595-609 (2012).
25. Tomoda, K. et al. Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell 11, 91-99 (2012).
26. Silva, J. et al. Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Developmental cell 4, 481-495 (2003).
27. Plath, K. et al. Role of histone H3 lysine 27 methylation in X inactivation. Science 300, 131-135 (2003).
28. Bao, S. et al. Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461, 1292-1295 (2009).
29. Rais, Y. et al. Deterministic direct reprogramming of somatic cells to pluripotency. Nature 502, 65-70 (2013).
30. Cheung, A. Y., Horvath, L. M., Carrel, L. & Ellis, J. X-chromosome inactivation in rett syndrome human induced pluripotent stem cells. Front Psychiatry 3, 24 (2012).
31. Penny, G. D., Kay, G. F., Sheardown, S. A., Rastan, S. & Brockdorff, N. Requirement for Xist in X chromosome inactivation. Nature 379, 131-137 (1996).
32. Matsui, Y., Zsebo, K. & Hogan, B. L. Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell 70, 841-847 (1992).
33. Amit, M. et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev. Biol. 227, 271-278 (2000).
34. Levenstein, M. E. et al. Basic fibroblast growth factor support of human embryonic stem cell self-renewal. Stem Cells 24, 568-574 (2006).
35. Yu, J. et al. Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801 (2009).
36. Quang, T., Marquez, M., Blanco, G. & Zhao, Y. Dosage and cell line dependent inhibitory effect of bFGF supplement in human pluripotent stem cell culture on inactivated human mesenchymal stem cells. PLoS One 9, e86031 (2014).
37. Chen, G. et al. Chemically defined conditions for human iPSC derivation and culture. Nat. Methods 8, 424-429 (2011).
38. Beers, J. et al. Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat. Protoc. 7, 2029-2040 (2012).
39. Ludwig, T. E. et al. Feeder-independent culture of human embryonic stem cells. Nat. Methods 3, 637-646 (2006).
40. Schwartz, P. H. & Wesselschmidt, R. L. Human pluripotent stem cells : methods and protocols. (Humana ; Springer, New York; 2011).
41. Sullivan, S., Cowan, C. & Eggan, K. Human embryonic stem cells : the practical handbook. (John Wiley & Sons, Chichester, West Sussex, England; Hoboken, NJ; 2007).
42. Stephenson, E. et al. Derivation and propagation of human embryonic stem cell lines from frozen embryos in an animal productfree environment. Nat. Protoc. 7, 1366-1381 (2012).
43. Zavazava, N. Embryonic stem cell immunobiology : methods and protocols. ((Humana Press ; Springer, , New York, ; 2013).
44. Kent, L. Culture and maintenance of human embryonic stem cells. J Vis Exp. 34, 1427 (2009).
45. Wu, M., Chen, G. & Hu, B. Induced pluripotency for translational research. Genomics Proteomics Bioinformatics 11, 288-293 (2013).
46. Valamehr, B. et al. A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs. Sci. Rep. 2, 213 (2012).
47. Lessing, D., Anguera, M. C. & Lee, J. T. X. Chromosome Inactivation and Epigenetic Responses to Cellular Reprogramming. Annu. Rev. Genom. Hum. G. 14, 85-110 (2013).
48. Tchieu, J. et al. Female Human iPSCs Retain an Inactive X Chromosome. Cell Stem Cell 7, 329-342 (2010).
49. Amenduni, M. et al. iPS cells to model CDKL5-related disorders. Eur. J. Hum. Genet. 19, 1246-1255 (2011).
50. Cheung, A. Y. L. et al. Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Human Molecular Genetics 20, 2103-2115 (2011).
51. Pomp, O. et al. Unexpected X Chromosome Skewing during Culture and Reprogramming of Human Somatic Cells Can Be Alleviated by Exogenous Telomerase. Cell Stem Cell 9, 156-165 (2011).
52. Kim, D. et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472-476 (2009).
53. Lengner, C.J. et al. Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell 141, 872-883 (2010).
54. Hanna, J. et al. Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proc. Natl. Acad. Sci. U S A 107, 9222-9227 (2010).