Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii

Cell

Volumn 123, Issue 6, 2005, Pages 1013-1023

  Martinez, Juan J ^a,b,c,e   Seveau, Stéphanie ^a,b,c   Veiga, Esteban ^a,b,c   Matsuyama, Shigemi ^d   Cossart, Pascale ^a,b,c  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c USC 2020   (France)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CBL PROTEIN; CHOLESTEROL; DNA DEPENDENT PROTEIN KINASE; KU ANTIGEN; PROTEIN SUBUNIT; UBIQUITIN PROTEIN LIGASE;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; CELL INVASION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RICKETTSIA CONORII; UBIQUITINATION;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; RICKETTSIA CONORII;

EID: 28944447801     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2005.08.046     Document Type: Article

References (54)

1. S.G. Andersson, A. Zomorodipour, J.O. Andersson, T. Sicheritz-Ponten, U.C. Alsmark, R.M. Podowski, A.K. Naslund, A.S. Eriksson, H.H. Winkler, and C.G. Kurland The genome sequence of Rickettsia prowazekii and the origin of mitochondria Nature 396 1998 133 140
2. D. Bandyopadhyay, M. Mandal, L. Adam, J. Mendelsohn, and R. Kumar Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells J. Biol. Chem. 273 1998 1568 1573
3. M. Carl, M.E. Dobson, W.M. Ching, and G.A. Dasch Characterization of the gene encoding the protective paracrystalline-surface-layer protein of Rickettsia prowazekii: presence of a truncated identical homolog in Rickettsia typhi Proc. Natl. Acad. Sci. USA 87 1990 8237 8241
4. J.Y. Chan, M.I. Lerman, B.S. Prabhakar, O. Isozaki, P. Santisteban, R.C. Kuppers, E.L. Oates, A.L. Notkins, and L.D. Kohn Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen J. Biol. Chem. 264 1989 3651 3654
5. D.R. Clifton, R.A. Goss, S.K. Sahni, D. van Antwerp, R.B. Baggs, V.J. Marder, D.J. Silverman, and L.A. Sporn NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection Proc. Natl. Acad. Sci. USA 95 1998 4646 4651
6. S.D. Conner, and S.L. Schmid Regulated portals of entry into the cell Nature 422 2003 37 44
7. P. Cossart, and P.J. Sansonetti Bacterial invasion: the paradigms of enteroinvasive pathogens Science 304 2004 242 248
8. P. Cossart, J. Pizarro-Cerda, and M. Lecuit Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions Trends Cell Biol. 13 2003 23 31
9. A.E. Engqvist-Goldstein, and D.G. Drubin Actin assembly and endocytosis: from yeast to mammals Annu. Rev. Cell Dev. Biol. 19 2003 287 332
10. H.M. Feng, T. Whitworth, J.P. Olano, V.L. Popov, and D.H. Walker Fc-dependent polyclonal antibodies and antibodies to outer membrane proteins A and B, but not to lipopolysaccharide, protect SCID mice against fatal Rickettsia conorii infection Infect. Immun. 72 2004 2222 2228
11. H.M. Feng, T. Whitworth, V. Popov, and D.H. Walker Effect of antibody on the rickettsia-host cell interaction Infect. Immun. 72 2004 3524 3530
12. S. Galande, and T. Kohwi-Shigematsu Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences J. Biol. Chem. 274 1999 20521 20528
13. E. Gouin, H. Gantelet, C. Egile, I. Lasa, H. Ohayon, V. Villiers, P. Gounon, P.J. Sansonetti, and P. Cossart A comparative study of the actin-based motilities of the pathogenic bacteria Listeria monocytogenes, Shigella flexneri and Rickettsia conorii J. Cell Sci. 112 1999 1697 1708
14. E. Gouin, C. Egile, P. Dehoux, V. Villiers, J. Adams, F. Gertler, R. Li, and P. Cossart The RickA protein of Rickettsia conorii activates the Arp2/3 complex Nature 427 2004 457 461
15. T. Hackstadt The biology of rickettsiae Infect. Agents Dis. 5 1996 127 143
16. T. Hackstadt, R. Messer, W. Cieplak, and M.G. Peacock Evidence for proteolytic cleavage of the 120-kilodalton outer membrane protein of rickettsiae: identification of an avirulent mutant deficient in processing Infect. Immun. 60 1992 159 165
17. K. Haglund, S. Sigismund, S. Polo, I. Szymkiewicz, P.P. Di Fiore, and I. Dikic Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation Nat. Cell Biol. 5 2003 461 466
18. W.L. Hand, J.B. Miller, J.A. Reinarz, and J.P. Sanford Rocky Mountain spotted fever. A vascular disease Arch. Intern. Med. 125 1970 879 882
19. K.O. Hartley, D. Gell, G.C. Smith, H. Zhang, N. Divecha, M.A. Connelly, A. Admon, S.P. Lees-Miller, C.W. Anderson, and S.P. Jackson DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product Cell 82 1995 849 856
20. I.R. Henderson, F. Navarro-Garcia, M. Desvaux, R.C. Fernandez, and D. Ala'Aldeen Type V protein secretion pathway: the autotransporter story Microbiol. Mol. Biol. Rev. 68 2004 692 744
21. R.L. Jeng, E.D. Goley, J.A. D'Alessio, O.Y. Chaga, T.M. Svitkina, G.G. Borisy, R.A. Heinzen, and M.D. Welch A Rickettsia WASP-like protein activates the Arp2/3 complex and mediates actin-based motility Cell. Microbiol. 6 2004 761 769
22. S.G. Joshi, C.W. Francis, D.J. Silverman, and S.K. Sahni Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity Infect. Immun. 71 2003 4127 4136
23. E.P. Kilsdonk, P.G. Yancey, G.W. Stoudt, F.W. Bangerter, W.J. Johnson, M.C. Phillips, and G.H. Rothblat Cellular cholesterol efflux mediated by cyclodextrins J. Biol. Chem. 270 1995 17250 17256
24. M. Koike Dimerization, translocation and localization of Ku70 and Ku80 proteins J. Radiat. Res. (Tokyo) 43 2002 223 236
25. H. Li, and D.H. Walker rOmpA is a critical protein for the adhesion of Rickettsia rickettsii to host cells Microb. Pathog. 24 1998 289 298
26. E. London, and D.A. Brown Insolubility of lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts) Biochim. Biophys. Acta 1508 2000 182 195
27. H. Lucero, D. Gae, and G.E. Taccioli Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response J. Biol. Chem. 278 2003 22136 22143
28. S. Manes, G. del Real, and A.C. Martinez Pathogens: raft hijackers Nat. Rev. Immunol. 3 2003 557 568
29. M.D. Marmor, and Y. Yarden Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases Oncogene 23 2004 2057 2070
30. J.J. Martinez, and P. Cossart Early signaling events involved in the entry of Rickettsia conorii into mammalian cells J. Cell Sci. 117 2004 5097 5106
31. J. Mengaud, H. Ohayon, P. Gounon, R.M. Mege, and P. Cossart E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells Cell 84 1996 923 932
32. S. Monferran, C. Muller, L. Mourey, P. Frit, and B. Salles The Membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin J. Mol. Biol. 337 2004 503 511
33. S. Monferran, J. Paupert, S. Dauvillier, B. Salles, and C. Muller The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9 EMBO J. 23 2004 3758 3768
34. R. Mora, V.L. Bonilha, A. Marmorstein, P.E. Scherer, D. Brown, M.P. Lisanti, and E. Rodriguez-Boulan Caveolin-2 localizes to the golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1 J. Biol. Chem. 274 1999 25708 25717
35. C. Muller, J. Paupert, S. Monferran, and B. Salles The double life of the Ku protein: facing the DNA breaks and the extracellular environment Cell Cycle 4 2005 438 441
36. H. Ogata, S. Audic, P. Renesto-Audiffren, P.E. Fournier, V. Barbe, D. Samson, V. Roux, P. Cossart, J. Weissenbach, J.M. Claverie, and D. Raoult Mechanisms of evolution in Rickettsia conorii and R. prowazekii Science 293 2001 2093 2098
37. J.T. Parsons Focal adhesion kinase: the first ten years J. Cell Sci. 116 2003 1409 1416
38. A. Petrelli, G.F. Gilestro, S. Lanzardo, P.M. Comoglio, N. Migone, and S. Giordano The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met Nature 416 2002 187 190
39. L.E. Ramm, and H.H. Winkler Identification of cholesterol in the receptor site for rickettsiae on sheep erythrocyte membranes Infect. Immun. 13 1976 120 126
40. C. Saveanu, A. Namane, P.E. Gleizes, A. Lebreton, J.C. Rousselle, J. Noaillac-Depeyre, N. Gas, A. Jacquier, and M. Fromont-Racine Sequential protein association with nascent 60S ribosomal particles Mol. Cell. Biol. 23 2003 4449 4460
41. M. Sawada, W. Sun, P. Hayes, K. Leskov, D.A. Boothman, and S. Matsuyama Ku70 suppresses the apoptotic translocation of Bax to mitochondria Nat. Cell Biol. 5 2003 320 329
42. S. Seveau, H. Bierne, S. Giroux, M.C. Prevost, and P. Cossart Role of lipid rafts in E-cadherin - and HGF-R/Met - mediated entry of Listeria monocytogenes into host cells J. Cell Biol. 166 2004 743 753
43. J.S. Shin, and S.N. Abraham Caveolae as portals of entry for microbes Microbes Infect. 3 2001 755 761
44. S.B. Sieczkarski, and G.R. Whittaker Viral entry Curr. Top. Microbiol. Immunol. 285 2005 1 23
45. P. Soubeyran, K. Kowanetz, I. Szymkiewicz, W.Y. Langdon, and I. Dikic Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors Nature 416 2002 183 187
46. T.E. Taher, E.P. Tjin, E.A. Beuling, J. Borst, M. Spaargaren, and S.T. Pals c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination J. Immunol. 169 2002 3793 3800
47. T. Uchiyama Adherence to and invasion of Vero cells by recombinant Escherichia coli expressing the outer membrane protein rOmpB of Rickettsia japonica Ann. N Y Acad. Sci. 990 2003 585 590
48. E. Veiga, and P. Cossart Listeria triggers the ubiquitin dependent endocytosis of Met for invasion of mammalian cells Nat. Cell Biol. 2005 in press
49. S. Vishwanath Antigenic relationships among the rickettsiae of the spotted fever and typhus groups FEMS Microbiol. Lett. 65 1991 341 344
50. D.H. Walker, and J.H. Gear Correlation of the distribution of Rickettsia conorii, microscopic lesions, and clinical features in South African tick bite fever Am. J. Trop. Med. Hyg. 34 1985 361 371
51. D.H. Walker, W.T. Firth, J.G. Ballard, and B.C. Hegarty Role of phospholipase-associated penetration mechanism in cell injury by Rickettsia rickettsii Infect. Immun. 40 1983 840 842
52. D.H. Walker, C. Occhino, G.R. Tringali, S. Di Rosa, and S. Mansueto Pathogenesis of rickettsial eschars: the tache noire of boutonneuse fever Hum. Pathol. 19 1988 1449 1454
53. P. Yagupsky, and B. Wolach Fatal Israeli spotted fever in children Clin. Infect. Dis. 17 1993 850 853
54. D. Yarar, C.M. Waterman-Storer, and S.L. Schmid A dynamic actin cytoskeleton functions at multiple stages of clathrin-mediated endocytosis Mol. Biol. Cell 16 2005 964 975