Transformation assay in Bhas 42 cells: A model using initiated cells to study mechanisms of carcinogenesis and predict carcinogenic potential of chemicals

Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews

Volumn 33, Issue 1, 2015, Pages 1-35

  Sasaki, Kiyoshi ^a   Umeda, Makoto ^a   Sakai, Ayako ^a   Yamazaki, Shojiro ^a   Tanaka, Noriho ^a  

^a HATANO RESEARCH INSTITUTE   (Japan)

Author keywords

Bhas 42 cells; cell transformation assay; screening; tumor promoters; v Ha ras

Indexed keywords

ASSAYS; CARCINOGENS; CELL CULTURE; CELLS; CLONE CELLS; CYTOLOGY; DIAGNOSIS; GENES; PATHOLOGY; SCREENING; TISSUE CULTURE; TUMORS;

CARCINOGENIC POTENTIAL; CELL TRANSFORMATION; HIGH SENSITIVITY; MULTI-STAGE MODELS; NONGENOTOXIC CARCINOGENS; ONCOGENIC POTENTIAL; TUMOR PROMOTERS; VALIDATION STUDY;

MOLECULAR BIOLOGY;

CARCINOGEN; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR PROMOTER;

ANIMAL CELL CULTURE; ARTICLE; CARCINOGENESIS; CARCINOGENICITY; CELL ASSAY; CELL TRANSFORMATION; CHROMOSOME; CLONE; COCULTURE; DNA SEQUENCE; EMBRYO CELL; EVOLUTION; GENE DOSAGE; GENETIC TRANSFECTION; HUMAN; MORPHOLOGY; NONHUMAN; ONCOGENE RAS; PROMOTER REGION; SENSITIVITY ANALYSIS; SYRIAN HAMSTER; VALIDATION STUDY; 3T3 CELL LINE; ANIMAL; BAGG ALBINO MOUSE; CARCINOGEN TESTING; CHEMICALLY INDUCED; MOUSE; PROCEDURES;

MESOCRICETUS AURATUS;

ANIMALS; BALB 3T3 CELLS; CARCINOGENICITY TESTS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; MICE; MICE, INBRED BALB C;

EID: 84929086033     PISSN: 10590501     EISSN: 15324095     Source Type: Journal    
DOI: 10.1080/10590501.2014.967058     Document Type: Article

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