An inter-laboratory collaborative study by the non-genotoxic carcinogen study group in Japan, on a cell transformation assay for tumour promoters using Bhas 42 cells

ATLA Alternatives to Laboratory Animals

Volumn 33, Issue 6, 2005, Pages 619-639

  Ohmori, Kiyomi ^a   Umeda, Makoto ^b   Tanaka, Noriho ^b   Takagi, Hiroki ^c   Yoshimura, Isao ^d   Sasaki, Kiyoshi ^b   Asada, Shin ^b   Sakai, Ayako ^e   Araki, Harumi ^f   Asakura, Masumi ^g   Baba, Hiroshi ^h   Fushiwaki, Yuichi ^a   Hamada, Shuichi ⁱ   Kitou, Nobuko ^f   Nakamura, Tetsu ^j   Nakamura, Yoshiyuki ^k   Oishi, Hidetoshi ^l   Sasaki, Satoshi ^m   Shimada, Sawako ⁿ   Tsuchiya, Toshiyuki ^o   Uno, Yoshifumi ^h   Washizuka, Masataka ^p   Yajima, Satoshi ^m   Yamamoto, Yasuhito ^q   Yamamura, Eiji ^h   Yatsushiro, Tomoko ^j   more..

^a KANAGAWA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b HATANO RESEARCH INSTITUTE   (Japan)

^c Aventis Pharma Ltd   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

^e NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^f Japan Bioassay Research Center   (Japan)

^g MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^h MITSUBISHI CHEMICAL CORPORATION   (Japan)

ⁱ TOYAMA CHEMICAL CO LTD   (Japan)

^j CANON INC   (Japan)

^k SUGIYAMA JOGAKUEN UNIVERSITY   (Japan)

^l DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^m TAKASAGO INTERNATIONAL CORPORATION   (Japan)

ⁿ Biosafety Research Center Foods Drugs and Pesticides   (Japan)

^o Banyu Pharmaceutical Co Ltd   (Japan)

^p ZERIA PHARMACEUTICAL CO LTD   (Japan)

^q LION CORPORATION   (Japan)

more..

Author keywords

Bhas 42 cells; Cell transformation assay; Inter laboratory collaborative study; Tumour promoter

Indexed keywords

CATECHOL; INSULIN; LITHOCHOLIC ACID; MEZEREIN; OKADAIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL DIDECANOATE; PROGESTERONE; SACCHARIN SODIUM; TUMOR PROMOTER;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN; CELL STRAIN BHAS 42; CELL TRANSFORMATION; CONCENTRATION (PARAMETERS); GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 31444451811     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290503300616     Document Type: Article

References (17)

1. Sugimura, T. (1992). Multistep carcinogenesis: a 1992 perspective. Science, New York 259, 603-607.
2. OECD (1997). Guidelines for Testing of Chemicals. Section 4. Health Effects. Paris, France: Organization for Economic Co-operation and Development. Website http://www.oecd.org/document/55/ 0,2340,en_2649_34377_2349687_1_1_1_1, 00.html
3. Kakunaga, T. (1973). A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB/3T3. International Journal of Cancer 12, 463-473.
4. Reznikoff, C.A., Bertram, J.S., Brankow, D.W. & Heidelberger, C. (1973). Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Research 33, 3239-3249.
5. Hallowell, A., Tu, W., Pallotta, S., Sivak, A., Lubet, R.A., Curren, R.D., Avery, M.D., Jones, C., Sedita, B.A. & Huberman, E. (1986). An interlaboratory comparison of transformation in Syrian hamster embryo cells with model and coded chemicals. Environmental Mutagenesis 8, 77-98.
6. Tsuchiya, T. & Umeda, M. (1995). Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells. Carcinogenesis 16, 1887-1894.
7. Yotti, L.P., Chang, C.C. & Trosko, J.E. (1979). Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science, New York 206, 1089-1091.
8. Murray, A.W. & Fitzgerald, D.J. (1979). Tumor promoters inhibit metabolic cooperation in co-cultures of epidermal and 3T3 cells. Biochemical and Biophysical Research Communications 91, 395-401.
9. Umeda, M., Noda, K. & Ono, T. (1980). Inhibition of metabolic cooperation in Chinese hamster cells by various chemicals including tumor promoters. Japanese Journal of Cancer Research (Gann) 71, 614-620.
10. Rovera, G., Santoli, D. & Damsky, C. (1979). Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester. Proceedings of the National Academy of Sciences of the USA 76, 2779-2783.
11. Ito, Y., Yanase, S., Fujita, J., Harayama, T., Takashima, M. & Imanaka, H. (1981). A short-term in vitro assay for promoter substances using human lymphoblastoid cells latently infected with Epstein-Barr virus. Cancer Letters 13, 29-37.
12. Ohmori, K., Miyazaki, K. & Umeda, M. (1998). Detection of tumor promoters by early antigen expression of EB virus in Raji cells using a fluorescence microplate-reader. Cancer Letters 132, 51-59.
13. Busser, M.T. & Lutz, W.K. (1987). Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters. Carcinogenesis 81, 1433-1437.
14. Ohmori, K., Sasaki, K, Asada, S., Tanaka, N. & Umeda, M. (2004). An assay method for the prediction of tumor promoting potential of chemicals by the use of Bhas 42 cells. Mutation Research 557, 191-202.
15. Nagasawa, H., Mori, T. & Nakajima, Y. (1980). Long-term effects of progesterone or diethylstilbestrol with or without estrogen after maturity on mammary tumorigenesis in mice. European Journal of Cancer 16, 1583-1589.
16. Huseby, R.A. (1980). Demonstration of a direct carcinogenic effect of estradiol on Leydig cells of the mouse. Cancer Research 40, 1006-1013.
17. Asada, S., Sasaki, K., Tanaka, N., Takeda, K., Hayashi, M. & Umeda, M. (2005). Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Ha-ras-transfected BALB/c3T3 cells (Bhas 42 cells). Mutation Research 588, 7-21.