An international validation study of a Bhas 42 cell transformation assay for the prediction of chemical carcinogenicity

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 725, Issue 1-2, 2011, Pages 57-77

  Sakai, Ayako ^a   Sasaki, Kiyoshi ^a   Hayashi, Kumiko ^a   Muramatsu, Dai ^a   Arai, Shoko ^a   Endou, Nobuko ^a   Kuroda, Sachiko ^a   Poth, Albrecht ^b   Bohnenberger, Susanne ^b   Kunkelmann, Thorsten ^b   Asakura, Masumi ^c   Hirose, Hideki ^d   Ishii, Nana ^d   Mizuhashi, Fukutaro ^e   Kasamoto, Sawako ^e   Nagai, Miho ^e   Pant, Kamala ^f   Bruce, Shannon W ^f   Sly, Jamie E ^f   Yamazaki, Shojiro ^a   Umeda, Makoto ^a   Tanaka, Noriho ^a   more..

^a HATANO RESEARCH INSTITUTE   (Japan)

^b Harlan   (Switzerland)

^c Japan Bioassay Research Center   (Japan)

^d LSI MEDIENCE CORPORATION   (Japan)

^e Biosafety Research Center   (Japan)

^f BioReliance Corporation   (United States)

Author keywords

Bhas 42 cells; Cell transformation; Tumor initiator; Tumor promoter; V Ha ras

Indexed keywords

ANTHRACENE; ARSENITE SODIUM; ASCORBIC ACID; CADMIUM CHLORIDE; CAFFEINE; CARCINOGEN; CHEMICAL COMPOUND; DIBENZ[A,H]ANTHRACENE; LITHOCHOLIC ACID; MANNITOL; METHAPYRILENE; MEZEREIN; N (2 FLUORENYL)ACETAMIDE; ORTHO TOLUIDIN HYDROCHLORIDE; RAS PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CARCINOGENICITY; CELL ASSAY; CELL STRAIN; CELL TRANSFORMATION; COMPARATIVE STUDY; CONTROLLED STUDY; LABORATORY; PREDICTION; PRIORITY JOURNAL; REPRODUCIBILITY; VALIDATION STUDY;

ANIMALS; BALB 3T3 CELLS; CARCINOGENICITY TESTS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; GENES, RAS; MICE; REPRODUCIBILITY OF RESULTS;

EID: 80052407074     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.07.006     Document Type: Article

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