Photo catalogue for the classification of foci in the BALB/c 3T3 cell transformation assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 744, Issue 1, 2012, Pages 42-53

  Sasaki, Kiyoshi ^a   Bohnenberger, Susanne ^b   Hayashi, Kumiko ^a   Kunkelmann, Thorsten ^b   Muramatsu, Dai ^a   Poth, Albrecht ^b   Sakai, Ayako ^a   Salovaara, Susan ^c   Tanaka, Noriho ^a   Thomas, B Claire ^c   Umeda, Makoto ^a  

^a HATANO RESEARCH INSTITUTE   (Japan)

^b Harlan   (Switzerland)

^c JOINT RESEARCH CENTRE   (Italy)

Author keywords

BALB c 3T3 cell line; Carcinogenicity; Cell transformation assay; Photo catalogue; Transformed foci

Indexed keywords

ANIMAL CELL; ARTICLE; AUDIOVISUAL EQUIPMENT; CELL ASSAY; CELL STRAIN 3T3; CELL TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM;

ANIMAL TESTING ALTERNATIVES; ANIMALS; AUDIOVISUAL AIDS; BALB 3T3 CELLS; CARCINOGENICITY TESTS; CARCINOGENS; CATALOGS AS TOPIC; CELL TRANSFORMATION, NEOPLASTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; PHOTOGRAPHY;

EID: 84859430056     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.01.009     Document Type: Article

References (5)

1. Tanaka N., Bohnenberger S., Kunkelmann T., Munaro B., Ponti J., Poth A., Sabbioni E., Sakai A., Salovaara S., Sasaki K., Thomas B.C., Umeda M. Prevalidation study of the BALB/c 3T3 cell transformation assay for assessment of carcinogenic potential of chemicals. Mutat. Res. 2012, 744:20-29.
2. Sasaki K., Bohnenberger S., Hayashi K., Kunkelmann T., Muramatsu D., Phrakonkham P., Poth A., Sakai A., Salovaara S., Tanaka N., Thomas B.C., Umeda M. Recommended protocol for the Balb/c 3T3 cell transformation assay. Mutat. Res. 2012, 744:30-35.
3. Kakunaga T. Quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB/c 3T3. Int. J. Cancer 1973, 12:463-473.
4. Cellular and molecular mechanisms of cell transformation and standardization of transformation assays of established cell lines for the prediction of carcinogenic chemicals: overview and recommended protocols. Cancer Res. 1985, 45:2395-2399. IARC/NCI/EPA Working Group.
5. Reznikoff C.A., Bertram J.S., Brankow D.W., Heidelberger C. Qualitative and quantitative studies of chemical transformation of cloned C3H embryo cells sensitive to postconfluence inhibition of cell division. Cancer Res. 1973, 33:3239-3249.