-
1
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
P. Carmeliet, Y. Dor, J.M. Herbert, D. Fukumura, K. Brusselmans, M. Dewerchin, M. Neeman, F. Bono, R. Abramovitch, and P. Maxwell Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature 394 1998 485 490
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
Fukumura, D.4
Brusselmans, K.5
Dewerchin, M.6
Neeman, M.7
Bono, F.8
Abramovitch, R.9
Maxwell, P.10
-
3
-
-
67649980040
-
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
-
R. Chowdhury, M.A. McDonough, J. Mecinović, C. Loenarz, E. Flashman, K.S. Hewitson, C. Domene, and C.J. Schofield Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases Structure 17 2009 981 989
-
(2009)
Structure
, vol.17
, pp. 981-989
-
-
Chowdhury, R.1
McDonough, M.A.2
Mecinović, J.3
Loenarz, C.4
Flashman, E.5
Hewitson, K.S.6
Domene, C.7
Schofield, C.J.8
-
4
-
-
25644446823
-
Hypoxia-responsive transcription factors
-
E.P. Cummins, and C.T. Taylor Hypoxia-responsive transcription factors Pflugers Arch. 450 2005 363 371
-
(2005)
Pflugers Arch.
, vol.450
, pp. 363-371
-
-
Cummins, E.P.1
Taylor, C.T.2
-
5
-
-
84883514161
-
Targeting lactate metabolism for cancer therapeutics
-
J.R. Doherty, and J.L. Cleveland Targeting lactate metabolism for cancer therapeutics J. Clin. Invest. 123 2013 3685 3692
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3685-3692
-
-
Doherty, J.R.1
Cleveland, J.L.2
-
6
-
-
33744954065
-
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: The role of HIF-1alpha, HIF-2alpha, and other pathways
-
G.P. Elvidge, L. Glenny, R.J. Appelhoff, P.J. Ratcliffe, J. Ragoussis, and J.M. Gleadle Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways J. Biol. Chem. 281 2006 15215 15226
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15215-15226
-
-
Elvidge, G.P.1
Glenny, L.2
Appelhoff, R.J.3
Ratcliffe, P.J.4
Ragoussis, J.5
Gleadle, J.M.6
-
7
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
V.R. Fantin, J. St-Pierre, and P. Leder Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance Cancer Cell 9 2006 425 434
-
(2006)
Cancer Cell
, vol.9
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
8
-
-
49949152069
-
Mechanisms of adaptive angiogenesis to tissue hypoxia
-
G.H. Fong Mechanisms of adaptive angiogenesis to tissue hypoxia Angiogenesis 11 2008 121 140
-
(2008)
Angiogenesis
, vol.11
, pp. 121-140
-
-
Fong, G.H.1
-
9
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
A.L. Harris Hypoxia - a key regulatory factor in tumour growth Nat. Rev. Cancer 2 2002 38 47
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
10
-
-
0037093107
-
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor
-
G. Höpfl, R.H. Wenger, U. Ziegler, T. Stallmach, O. Gardelle, R. Achermann, M. Wergin, B. Kaser-Hotz, H.M. Saunders, and K.J. Williams Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor Cancer Res. 62 2002 2962 2970
-
(2002)
Cancer Res.
, vol.62
, pp. 2962-2970
-
-
Höpfl, G.1
Wenger, R.H.2
Ziegler, U.3
Stallmach, T.4
Gardelle, O.5
Achermann, R.6
Wergin, M.7
Kaser-Hotz, B.8
Saunders, H.M.9
Williams, K.J.10
-
11
-
-
77952107920
-
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis
-
A.M. Jubb, F.M. Buffa, and A.L. Harris Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis J. Cell. Mol. Med. 14 2010 18 29
-
(2010)
J. Cell. Mol. Med.
, vol.14
, pp. 18-29
-
-
Jubb, A.M.1
Buffa, F.M.2
Harris, A.L.3
-
12
-
-
76649126249
-
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
-
A. Le, C.R. Cooper, A.M. Gouw, R. Dinavahi, A. Maitra, L.M. Deck, R.E. Royer, D.L. Vander Jagt, G.L. Semenza, and C.V. Dang Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression Proc. Natl. Acad. Sci. USA 107 2010 2037 2042
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 2037-2042
-
-
Le, A.1
Cooper, C.R.2
Gouw, A.M.3
Dinavahi, R.4
Maitra, A.5
Deck, L.M.6
Royer, R.E.7
Vander Jagt, D.L.8
Semenza, G.L.9
Dang, C.V.10
-
13
-
-
79956317112
-
Von Hippel-Lindau disease: A clinical and scientific review
-
E.R. Maher, H.P. Neumann, and S. Richard von Hippel-Lindau disease: a clinical and scientific review Eur. J. Hum. Genet. 19 2011 617 623
-
(2011)
Eur. J. Hum. Genet.
, vol.19
, pp. 617-623
-
-
Maher, E.R.1
Neumann, H.P.2
Richard, S.3
-
14
-
-
78649813933
-
The N-myc downstream regulated gene (NDRG) family: Diverse functions, multiple applications
-
V. Melotte, X. Qu, M. Ongenaert, W. van Criekinge, A.P. de Bruïne, H.S. Baldwin, and M. van Engeland The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications FASEB J. 24 2010 4153 4166
-
(2010)
FASEB J.
, vol.24
, pp. 4153-4166
-
-
Melotte, V.1
Qu, X.2
Ongenaert, M.3
Van Criekinge, W.4
De Bruïne, A.P.5
Baldwin, H.S.6
Van Engeland, M.7
-
15
-
-
1642329821
-
Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer
-
Y. Mizukami, J. Li, X. Zhang, M.A. Zimmer, O. Iliopoulos, and D.C. Chung Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer Cancer Res. 64 2004 1765 1772
-
(2004)
Cancer Res.
, vol.64
, pp. 1765-1772
-
-
Mizukami, Y.1
Li, J.2
Zhang, X.3
Zimmer, M.A.4
Iliopoulos, O.5
Chung, D.C.6
-
16
-
-
24744438663
-
Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells
-
Y. Mizukami, W.S. Jo, E.M. Duerr, M. Gala, J. Li, X. Zhang, M.A. Zimmer, O. Iliopoulos, L.R. Zukerberg, and Y. Kohgo Induction of interleukin-8 preserves the angiogenic response in HIF-1alpha-deficient colon cancer cells Nat. Med. 11 2005 992 997
-
(2005)
Nat. Med.
, vol.11
, pp. 992-997
-
-
Mizukami, Y.1
Jo, W.S.2
Duerr, E.M.3
Gala, M.4
Li, J.5
Zhang, X.6
Zimmer, M.A.7
Iliopoulos, O.8
Zukerberg, L.R.9
Kohgo, Y.10
-
17
-
-
35348909046
-
Hypoxia inducible factor-1 independent pathways in tumor angiogenesis
-
Y. Mizukami, Y. Kohgo, and D.C. Chung Hypoxia inducible factor-1 independent pathways in tumor angiogenesis Clin. Cancer Res. 13 2007 5670 5674
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5670-5674
-
-
Mizukami, Y.1
Kohgo, Y.2
Chung, D.C.3
-
18
-
-
31444436640
-
A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis
-
M.J. Percy, Q. Zhao, A. Flores, C. Harrison, T.R. Lappin, P.H. Maxwell, M.F. McMullin, and F.S. Lee A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis Proc. Natl. Acad. Sci. USA 103 2006 654 659
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 654-659
-
-
Percy, M.J.1
Zhao, Q.2
Flores, A.3
Harrison, C.4
Lappin, T.R.5
Maxwell, P.H.6
McMullin, M.F.7
Lee, F.S.8
-
19
-
-
74849127957
-
Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads
-
A. Rapisarda, R.H. Shoemaker, and G. Melillo Antiangiogenic agents and HIF-1 inhibitors meet at the crossroads Cell Cycle 8 2009 4040 4043
-
(2009)
Cell Cycle
, vol.8
, pp. 4040-4043
-
-
Rapisarda, A.1
Shoemaker, R.H.2
Melillo, G.3
-
20
-
-
0034193510
-
Protein docking using spherical polar Fourier correlations
-
D.W. Ritchie, and G.J. Kemp Protein docking using spherical polar Fourier correlations Proteins 39 2000 178 194
-
(2000)
Proteins
, vol.39
, pp. 178-194
-
-
Ritchie, D.W.1
Kemp, G.J.2
-
21
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
G.L. Semenza Targeting HIF-1 for cancer therapy Nat. Rev. Cancer 3 2003 721 732
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
22
-
-
2342661143
-
Intratumoral hypoxia, radiation resistance, and HIF-1
-
G.L. Semenza Intratumoral hypoxia, radiation resistance, and HIF-1 Cancer Cell 5 2004 405 406
-
(2004)
Cancer Cell
, vol.5
, pp. 405-406
-
-
Semenza, G.L.1
-
23
-
-
0037143512
-
Responding to hypoxia: Lessons from a model cell line
-
K.A. Seta, Z. Spicer, Y. Yuan, G. Lu, and D.E. Millhorn Responding to hypoxia: lessons from a model cell line Sci. STKE 2002 2002 re11
-
(2002)
Sci. STKE
, vol.2002
, pp. re11
-
-
Seta, K.A.1
Spicer, Z.2
Yuan, Y.3
Lu, G.4
Millhorn, D.E.5
-
24
-
-
49649114605
-
Protein structure modeling with MODELLER
-
N. Eswar, D. Eramian, B. Webb, M.Y. Shen, and A. Sali Protein structure modeling with MODELLER Methods Mol. Biol. 426 2008 145 159
-
(2008)
Methods Mol. Biol.
, vol.426
, pp. 145-159
-
-
Eswar, N.1
Eramian, D.2
Webb, B.3
Shen, M.Y.4
Sali, A.5
-
25
-
-
34547840192
-
GAzer: Gene set analyzer
-
S.B. Kim, S. Yang, S.K. Kim, S.C. Kim, H.G. Woo, D.J. Volsky, S.Y. Kim, and I.S. Chu GAzer: gene set analyzer Bioinformatics 23 2007 1697 1699
-
(2007)
Bioinformatics
, vol.23
, pp. 1697-1699
-
-
Kim, S.B.1
Yang, S.2
Kim, S.K.3
Kim, S.C.4
Woo, H.G.5
Volsky, D.J.6
Kim, S.Y.7
Chu, I.S.8
-
26
-
-
33749578940
-
Statistical potential for assessment and prediction of protein structures
-
M.Y. Shen, and A. Sali Statistical potential for assessment and prediction of protein structures Protein Sci. 15 2006 2507 2524
-
(2006)
Protein Sci.
, vol.15
, pp. 2507-2524
-
-
Shen, M.Y.1
Sali, A.2
|