-
1
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., et al. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993, 362(6415):59-62.
-
(1993)
Nature
, vol.362
, Issue.6415
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
2
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
Reaume A.G., Elliott J.L., Hoffman E.K., et al. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet. 1996, 13(1):43-47.
-
(1996)
Nat Genet.
, vol.13
, Issue.1
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
-
3
-
-
0029842923
-
Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis
-
Shibata N., Asayama K., Hirano A., Kobayashi M. Immunohistochemical study on superoxide dismutases in spinal cords from autopsied patients with amyotrophic lateral sclerosis. Dev Neurosci 1996, 18(5-6):492-498.
-
(1996)
Dev Neurosci
, vol.18
, Issue.5-6
, pp. 492-498
-
-
Shibata, N.1
Asayama, K.2
Hirano, A.3
Kobayashi, M.4
-
4
-
-
77958519939
-
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
-
Bosco D.A., Morfini G., Karabacak N.M., et al. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci 2010, 13(11):1396-1403.
-
(2010)
Nat Neurosci
, vol.13
, Issue.11
, pp. 1396-1403
-
-
Bosco, D.A.1
Morfini, G.2
Karabacak, N.M.3
-
5
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Sreedharan J., Blair I.P., Tripathi V.B., et al. TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis. Science. 2008, 319(5870):1668-1672.
-
(2008)
Science.
, vol.319
, Issue.5870
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
-
6
-
-
77953890823
-
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
-
Lagier-Tourenne C., Polymenidou M., Cleveland D.W. TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet 2010, 19(R1):R46-R64.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.R1
, pp. R46-R64
-
-
Lagier-Tourenne, C.1
Polymenidou, M.2
Cleveland, D.W.3
-
7
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K., et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006, 314(5796):130-133.
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
-
8
-
-
84883292041
-
Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
-
Brettschneider J., Del Tredici K., Toledo J.B., et al. Stages of pTDP-43 pathology in amyotrophic lateral sclerosis. Ann Neurol 2013, 74(1):20-38.
-
(2013)
Ann Neurol
, vol.74
, Issue.1
, pp. 20-38
-
-
Brettschneider, J.1
Del Tredici, K.2
Toledo, J.B.3
-
9
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski T.J., Bosco D.A., Leclerc A.L., et al. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 2009, 323(5918):1205-1208.
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1205-1208
-
-
Kwiatkowski, T.J.1
Bosco, D.A.2
Leclerc, A.L.3
-
10
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance C., Rogelj B., Hortobagyi T., et al. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science 2009, 323(5918):1208-1211.
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
-
11
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
Dejesus-Hernandez M., Mackenzie I.R., Boeve B.F., et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 2011, 72(2):245-256.
-
(2011)
Neuron
, vol.72
, Issue.2
, pp. 245-256
-
-
Dejesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
-
12
-
-
80054837386
-
A hexanucleotide repeat expansion in c9orf72 is the cause of chromosome 9p21-linked ALS-FTD
-
Renton A.E., Majounie E., Waite A., et al. A hexanucleotide repeat expansion in c9orf72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 2011, 72(2):257-268.
-
(2011)
Neuron
, vol.72
, Issue.2
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
-
13
-
-
84874962380
-
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS
-
Mori K., Weng S.M., Arzberger T., et al. The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS. Science 2013, 339(6125):1335-1338.
-
(2013)
Science
, vol.339
, Issue.6125
, pp. 1335-1338
-
-
Mori, K.1
Weng, S.M.2
Arzberger, T.3
-
14
-
-
84874272095
-
Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS
-
Ash P.E., Bieniek K.F., Gendron T.F., et al. Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS. Neuron 2013, 77(4):639-646.
-
(2013)
Neuron
, vol.77
, Issue.4
, pp. 639-646
-
-
Ash, P.E.1
Bieniek, K.F.2
Gendron, T.F.3
-
15
-
-
80052580969
-
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
-
Deng H.X., Chen W., Hong S.T., et al. Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Nature 2011, 477(7363):211-215.
-
(2011)
Nature
, vol.477
, Issue.7363
, pp. 211-215
-
-
Deng, H.X.1
Chen, W.2
Hong, S.T.3
-
16
-
-
77950529265
-
RNA-mediated neurodegeneration in repeat expansion disorders
-
Todd P.K., Paulson H.L. RNA-mediated neurodegeneration in repeat expansion disorders. Ann Neurol 2010, 67(3):291-300.
-
(2010)
Ann Neurol
, vol.67
, Issue.3
, pp. 291-300
-
-
Todd, P.K.1
Paulson, H.L.2
-
17
-
-
84865235172
-
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
-
Wu C.H., Fallini C., Ticozzi N., et al. Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis. Nature 2012, 488(7412):499-503.
-
(2012)
Nature
, vol.488
, Issue.7412
, pp. 499-503
-
-
Wu, C.H.1
Fallini, C.2
Ticozzi, N.3
-
18
-
-
84879796952
-
Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system
-
Kanaan N.M., Pigino G.F., Brady S.T., Lazarov O., Binder L.I., Morfini G.A. Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system. Exp Neurol 2013, 246:44-53.
-
(2013)
Exp Neurol
, vol.246
, pp. 44-53
-
-
Kanaan, N.M.1
Pigino, G.F.2
Brady, S.T.3
Lazarov, O.4
Binder, L.I.5
Morfini, G.A.6
-
19
-
-
84878900746
-
Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase
-
Morfini G.A., Bosco D.A., Brown H., et al. Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase. PLoS ONE 2013, 8(6):e65235.
-
(2013)
PLoS ONE
, vol.8
, Issue.6
-
-
Morfini, G.A.1
Bosco, D.A.2
Brown, H.3
-
20
-
-
4143084861
-
Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS
-
Munch C., Sedlmeier R., Meyer T., et al. Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS. Neurology 2004, 63(4):724-726.
-
(2004)
Neurology
, vol.63
, Issue.4
, pp. 724-726
-
-
Munch, C.1
Sedlmeier, R.2
Meyer, T.3
-
21
-
-
67049155508
-
Reduced expression of the kinesin-associated protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis
-
Landers J.E., Melki J., Meininger V., et al. Reduced expression of the kinesin-associated protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2009, 106(22):9004-9009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.22
, pp. 9004-9009
-
-
Landers, J.E.1
Melki, J.2
Meininger, V.3
-
22
-
-
6344257200
-
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
Nishimura A.L., Mitne-Neto M., Silva H.C., et al. A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis. Am J Hum Genet 2004, 75(5):822-831.
-
(2004)
Am J Hum Genet
, vol.75
, Issue.5
, pp. 822-831
-
-
Nishimura, A.L.1
Mitne-Neto, M.2
Silva, H.C.3
-
23
-
-
0037096354
-
Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
-
Lino M.M., Schneider C., Caroni P. Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J Neurosci 2002, 22(12):4825-4832.
-
(2002)
J Neurosci
, vol.22
, Issue.12
, pp. 4825-4832
-
-
Lino, M.M.1
Schneider, C.2
Caroni, P.3
-
24
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
Pramatarova A., Laganiere J., Roussel J., Brisebois K., Rouleau G.A. Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J Neurosci 2001, 21(10):3369-3374.
-
(2001)
J Neurosci
, vol.21
, Issue.10
, pp. 3369-3374
-
-
Pramatarova, A.1
Laganiere, J.2
Roussel, J.3
Brisebois, K.4
Rouleau, G.A.5
-
25
-
-
0141642203
-
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
-
Clement A.M., Nguyen M.D., Roberts E.A., et al. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 2003, 302(5642):113-117.
-
(2003)
Science
, vol.302
, Issue.5642
, pp. 113-117
-
-
Clement, A.M.1
Nguyen, M.D.2
Roberts, E.A.3
-
26
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillee S., Yamanaka K., Lobsiger C.S., et al. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006, 312(5778):1389-1392.
-
(2006)
Science
, vol.312
, Issue.5778
, pp. 1389-1392
-
-
Boillee, S.1
Yamanaka, K.2
Lobsiger, C.S.3
-
27
-
-
33750478657
-
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
-
Beers D.R., Henkel J.S., Xiao Q., et al. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 2006, 103(43):16021-16026.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.43
, pp. 16021-16026
-
-
Beers, D.R.1
Henkel, J.S.2
Xiao, Q.3
-
28
-
-
44649152645
-
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice
-
Yamanaka K., Boillee S., Roberts E.A., et al. Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice. Proc Natl Acad Sci U S A 2008, 105(21):7594-7599.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.21
, pp. 7594-7599
-
-
Yamanaka, K.1
Boillee, S.2
Roberts, E.A.3
-
29
-
-
34247475338
-
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
-
Nagai M., Re D.B., Nagata T., et al. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci 2007, 10(5):615-622.
-
(2007)
Nat Neurosci
, vol.10
, Issue.5
, pp. 615-622
-
-
Nagai, M.1
Re, D.B.2
Nagata, T.3
-
30
-
-
63149141363
-
Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice
-
Lobsiger C.S., Boillee S., McAlonis-Downes M., et al. Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice. Proc Natl Acad Sci U S A 2009, 106(11):4465-4470.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.11
, pp. 4465-4470
-
-
Lobsiger, C.S.1
Boillee, S.2
McAlonis-Downes, M.3
-
31
-
-
84876900163
-
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
-
Kang S.H., Li Y., Fukaya M., et al. Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci 2013, 16(5):571-579.
-
(2013)
Nat Neurosci
, vol.16
, Issue.5
, pp. 571-579
-
-
Kang, S.H.1
Li, Y.2
Fukaya, M.3
-
32
-
-
84864200035
-
Oligodendroglia metabolically support axons and contribute to neurodegeneration
-
Lee Y., Morrison B.M., Li Y., et al. Oligodendroglia metabolically support axons and contribute to neurodegeneration. Nature. 2012, 487(7408):443-448.
-
(2012)
Nature.
, vol.487
, Issue.7408
, pp. 443-448
-
-
Lee, Y.1
Morrison, B.M.2
Li, Y.3
-
33
-
-
52649143820
-
A common haplotype within the PON1 promoter region is associated with sporadic ALS
-
Landers J.E., Shi L., Cho T.J., et al. A common haplotype within the PON1 promoter region is associated with sporadic ALS. Amyotroph Lateral Scler 2008, 9(5):306-314.
-
(2008)
Amyotroph Lateral Scler
, vol.9
, Issue.5
, pp. 306-314
-
-
Landers, J.E.1
Shi, L.2
Cho, T.J.3
-
34
-
-
77954038587
-
Paraoxonase gene mutations in amyotrophic lateral sclerosis
-
Ticozzi N., LeClerc A.L., Keagle P.J., et al. Paraoxonase gene mutations in amyotrophic lateral sclerosis. Ann Neurol 2010, 68(1):102-107.
-
(2010)
Ann Neurol
, vol.68
, Issue.1
, pp. 102-107
-
-
Ticozzi, N.1
LeClerc, A.L.2
Keagle, P.J.3
-
35
-
-
84865071988
-
Evidence for an oligogenic basis of amyotrophic lateral sclerosis
-
van Blitterswijk M., van Es M.A., Hennekam E.A., et al. Evidence for an oligogenic basis of amyotrophic lateral sclerosis. Hum Mol Genet 2012, 21(17):3776-3784.
-
(2012)
Hum Mol Genet
, vol.21
, Issue.17
, pp. 3776-3784
-
-
van Blitterswijk, M.1
van Es, M.A.2
Hennekam, E.A.3
-
36
-
-
84868656581
-
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
-
Van Hoecke A., Schoonaert L., Lemmens R., et al. EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans. Nat Med 2012, 18(9):1418-1422.
-
(2012)
Nat Med
, vol.18
, Issue.9
, pp. 1418-1422
-
-
Van Hoecke, A.1
Schoonaert, L.2
Lemmens, R.3
-
37
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney M.E., Pu H., Chiu A.Y., et al. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 1994, 264(5166):1772-1775.
-
(1994)
Science
, vol.264
, Issue.5166
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
-
38
-
-
0035575761
-
Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease
-
Nagai M., Aoki M., Miyoshi I., et al. Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease. J Neurosci 2001, 21(23):9246-9254.
-
(2001)
J Neurosci
, vol.21
, Issue.23
, pp. 9246-9254
-
-
Nagai, M.1
Aoki, M.2
Miyoshi, I.3
-
39
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
Howland D.S., Liu J., She Y., et al. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci U S A 2002, 99(3):1604-1609.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.3
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
-
40
-
-
84874095172
-
SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy
-
Winer L., Srinivasan D., Chun S., et al. SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy. JAMA Neurol 2013, 70(2):201-207.
-
(2013)
JAMA Neurol
, vol.70
, Issue.2
, pp. 201-207
-
-
Winer, L.1
Srinivasan, D.2
Chun, S.3
-
41
-
-
80052936462
-
Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
-
Swarup V., Phaneuf D., Bareil C., et al. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain 2011, 134(Pt 9):2610-2626.
-
(2011)
Brain
, vol.134
, pp. 2610-2626
-
-
Swarup, V.1
Phaneuf, D.2
Bareil, C.3
-
42
-
-
77950421249
-
Transgenic rat model of neurodegeneration caused by mutation in the TDP gene
-
Zhou H., Huang C., Chen H., et al. Transgenic rat model of neurodegeneration caused by mutation in the TDP gene. PLoS Genet 2010, 6(3):e1000887.
-
(2010)
PLoS Genet
, vol.6
, Issue.3
-
-
Zhou, H.1
Huang, C.2
Chen, H.3
-
43
-
-
84880217322
-
Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
-
Tong J., Huang C., Bi F., et al. Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats. EMBO J 2013, 32(13):1917-1926.
-
(2013)
EMBO J
, vol.32
, Issue.13
, pp. 1917-1926
-
-
Tong, J.1
Huang, C.2
Bi, F.3
-
44
-
-
79953743204
-
FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration
-
Huang C., Zhou H., Tong J., et al. FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. PLoS Genet 2011, 7(3):e1002011.
-
(2011)
PLoS Genet
, vol.7
, Issue.3
-
-
Huang, C.1
Zhou, H.2
Tong, J.3
-
45
-
-
84875427900
-
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
-
Mitchell J.C., McGoldrick P., Vance C., et al. Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion. Acta Neuropathol 2013, 125(2):273-288.
-
(2013)
Acta Neuropathol
, vol.125
, Issue.2
, pp. 273-288
-
-
Mitchell, J.C.1
McGoldrick, P.2
Vance, C.3
-
46
-
-
84883352466
-
Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice
-
Shelkovnikova T.A., Peters O.M., Deykin A.V., et al. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. J Biol Chem 2013, 288(35):25266-25274.
-
(2013)
J Biol Chem
, vol.288
, Issue.35
, pp. 25266-25274
-
-
Shelkovnikova, T.A.1
Peters, O.M.2
Deykin, A.V.3
-
47
-
-
77956496676
-
A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease
-
Ramesh T., Lyon A.N., Pineda R.H., et al. A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease. Dis Model Mech 2010, 3(9-10):652-662.
-
(2010)
Dis Model Mech
, vol.3
, Issue.9-10
, pp. 652-662
-
-
Ramesh, T.1
Lyon, A.N.2
Pineda, R.H.3
-
48
-
-
34548740744
-
Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish
-
Lemmens R., Van Hoecke A., Hersmus N., et al. Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish. Hum Mol Genet 2007, 16(19):2359-2365.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.19
, pp. 2359-2365
-
-
Lemmens, R.1
Van Hoecke, A.2
Hersmus, N.3
-
49
-
-
84865564198
-
Neuromuscular effects of G93A-SOD1 expression in zebrafish
-
Sakowski S.A., Lunn J.S., Busta A.S., et al. Neuromuscular effects of G93A-SOD1 expression in zebrafish. Mol Neurodegener 2012, 7:44.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 44
-
-
Sakowski, S.A.1
Lunn, J.S.2
Busta, A.S.3
-
50
-
-
84885763677
-
Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS
-
Armstrong G.A., Drapeau P. Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS. Hum Mol Genet 2013, 22(21):4282-4292.
-
(2013)
Hum Mol Genet
, vol.22
, Issue.21
, pp. 4282-4292
-
-
Armstrong, G.A.1
Drapeau, P.2
-
51
-
-
84881531855
-
Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis
-
May 30, [Epub ahead of print.]
-
Ciura S., Lattante S., Le Ber I., et al. Loss of function of C9orf72 causes motor deficits in a zebrafish model of amyotrophic lateral sclerosis. Ann Neurol May 30, 2013, [Epub ahead of print.].
-
(2013)
Ann Neurol
-
-
Ciura, S.1
Lattante, S.2
Le Ber, I.3
-
52
-
-
54049142949
-
A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1
-
Watson M.R., Lagow R.D., Xu K., Zhang B., Bonini N.M. A drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1. J Biol Chem. 2008, 283(36):24972-24981.
-
(2008)
J Biol Chem.
, vol.283
, Issue.36
, pp. 24972-24981
-
-
Watson, M.R.1
Lagow, R.D.2
Xu, K.3
Zhang, B.4
Bonini, N.M.5
-
53
-
-
59249098430
-
An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of
-
Wang J., Farr G.W., Hall D.H., et al. An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of. Caenorhabditis elegans. PLoS Genet. 2009, 5(1):e1000350.
-
(2009)
Caenorhabditis elegans. PLoS Genet.
, vol.5
, Issue.1
-
-
Wang, J.1
Farr, G.W.2
Hall, D.H.3
-
54
-
-
84873591088
-
Dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration
-
Ikenaka K., Kawai K., Katsuno M., et al. dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration. PLoS ONE 2013, 8(2):e54511.
-
(2013)
PLoS ONE
, vol.8
, Issue.2
-
-
Ikenaka, K.1
Kawai, K.2
Katsuno, M.3
-
55
-
-
80052295767
-
Conversion of mouse and human fibroblasts into functional spinal motor neurons
-
Son E.Y., Ichida J.K., Wainger B.J., et al. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell 2011, 9(3):205-218.
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 205-218
-
-
Son, E.Y.1
Ichida, J.K.2
Wainger, B.J.3
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