-
1
-
-
68949212379
-
Lysine acetylation targets protein complexes and co-regulates major cellular functions
-
Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M, (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325: 834-840.
-
(2009)
Science
, vol.325
, pp. 834-840
-
-
Choudhary, C.1
Kumar, C.2
Gnad, F.3
Nielsen, M.L.4
Rehman, M.5
Walther, T.C.6
Olsen, J.V.7
Mann, M.8
-
2
-
-
84865726581
-
Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
-
Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV, (2012) Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Cell Rep 2: 419-431.
-
(2012)
Cell Rep
, vol.2
, pp. 419-431
-
-
Lundby, A.1
Lage, K.2
Weinert, B.T.3
Bekker-Jensen, D.B.4
Secher, A.5
Skovgaard, T.6
Kelstrup, C.D.7
Dmytriyev, A.8
Choudhary, C.9
Lundby, C.10
Olsen, J.V.11
-
3
-
-
61649089277
-
Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli
-
Zhang J, Sprung R, Pei J, Tan X, Kim S, Zhu H, Liu C-F, Grishin NV, Zhao Y, (2009) Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli. Mol Cell Proteomics 8: 215-225.
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 215-225
-
-
Zhang, J.1
Sprung, R.2
Pei, J.3
Tan, X.4
Kim, S.5
Zhu, H.6
Liu, C.-F.7
Grishin, N.V.8
Zhao, Y.9
-
4
-
-
33745800293
-
Interpreting the protein language using proteomics
-
Jensen ON, (2006) Interpreting the protein language using proteomics. Nat Rev Mol Cell Biol 7: 391-403.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 391-403
-
-
Jensen, O.N.1
-
5
-
-
84890644637
-
Status of large-scale analysis of post-translational modifications by mass spectrometry
-
Olsen JV, Mann M, (2013) Status of large-scale analysis of post-translational modifications by mass spectrometry. Mol Cell Proteomics 12: 3444-3452.
-
(2013)
Mol Cell Proteomics
, vol.12
, pp. 3444-3452
-
-
Olsen, J.V.1
Mann, M.2
-
6
-
-
34248640428
-
Lysine propionylation and butyrylation are novel post-translational modifications in histones
-
Chen Y, Sprung R, Tang Y, Ball H, Sangras B, Kim SC, Falck JR, Peng J, Gu W, Zhao Y, (2007) Lysine propionylation and butyrylation are novel post-translational modifications in histones. Mol Cell Proteomics 6: 812-819.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 812-819
-
-
Chen, Y.1
Sprung, R.2
Tang, Y.3
Ball, H.4
Sangras, B.5
Kim, S.C.6
Falck, J.R.7
Peng, J.8
Gu, W.9
Zhao, Y.10
-
7
-
-
80052942443
-
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
-
Tan M, Luo H, Lee S, Jin F, Yang Jeong S, Montellier E, Buchou T, Cheng Z, Rousseaux S, Rajagopal N, Lu Z, Ye Z, Zhu Q, Wysocka J, Ye Y, Khochbin S, Ren B, Zhao Y, (2011) Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146: 1016-1028.
-
(2011)
Cell
, vol.146
, pp. 1016-1028
-
-
Tan, M.1
Luo, H.2
Lee, S.3
Jin, F.4
Yang Jeong, S.5
Montellier, E.6
Buchou, T.7
Cheng, Z.8
Rousseaux, S.9
Rajagopal, N.10
Lu, Z.11
Ye, Z.12
Zhu, Q.13
Wysocka, J.14
Ye, Y.15
Khochbin, S.16
Ren, B.17
Zhao, Y.18
-
8
-
-
84861163510
-
Lysine succinylation and lysine malonylation in histones
-
Xie Z, Dai J, Dai L, Tan M, Cheng Z, Wu Y, Boeke JD, Zhao Y, (2012) Lysine succinylation and lysine malonylation in histones. Mol Cell Proteomics 11: 100-107.
-
(2012)
Mol Cell Proteomics
, vol.11
, pp. 100-107
-
-
Xie, Z.1
Dai, J.2
Dai, L.3
Tan, M.4
Cheng, Z.5
Wu, Y.6
Boeke, J.D.7
Zhao, Y.8
-
9
-
-
83055173304
-
The first identification of lysine malonylation substrates and its regulatory enzyme
-
M111.012658
-
Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BMM, Tishkoff D, Ho L, Lombard D, He T-C, Dai J, Verdin E, Ye Y, Zhao Y, (2011) The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics 10: M111.012658.
-
(2011)
Mol Cell Proteomics
, vol.10
-
-
Peng, C.1
Lu, Z.2
Xie, Z.3
Cheng, Z.4
Chen, Y.5
Tan, M.6
Luo, H.7
Zhang, Y.8
He, W.9
Yang, K.10
Zwaans, B.M.M.11
Tishkoff, D.12
Ho, L.13
Lombard, D.14
He, T.-C.15
Dai, J.16
Verdin, E.17
Ye, Y.18
Zhao, Y.19
-
10
-
-
78650516004
-
Identification of lysine succinylation as a new post-translational modification
-
Zhang Z, Tan M, Xie Z, Dai L, Chen Y, Zhao T, (2011) Identification of lysine succinylation as a new post-translational modification. Nat Chem Biol 7: 58-63.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 58-63
-
-
Zhang, Z.1
Tan, M.2
Xie, Z.3
Dai, L.4
Chen, Y.5
Zhao, T.6
-
11
-
-
84897565291
-
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5
-
Tan M, Peng C, Anderson Kristin A, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner Gregory R, Green Michelle F, Madsen Andreas S, Schmiesing J, Peterson Brett S, Xu G, Ilkayeva Olga R, Muehlbauer Michael J, Braulke T, Mühlhausen C, Backos Donald S, Olsen Christian A, McGuire Peter J, Pletcher Scott D, Lombard David B, Hirschey Matthew D, Zhao Y, (2014) Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. Cell Metab 19: 605-617.
-
(2014)
Cell Metab
, vol.19
, pp. 605-617
-
-
Tan, M.1
Peng, C.2
Anderson Kristin, A.3
Chhoy, P.4
Xie, Z.5
Dai, L.6
Park, J.7
Chen, Y.8
Huang, H.9
Zhang, Y.10
Ro, J.11
Wagner Gregory, R.12
Green Michelle, F.13
Madsen Andreas, S.14
Schmiesing, J.15
Peterson Brett, S.16
Xu, G.17
Ilkayeva Olga, R.18
Muehlbauer Michael, J.19
Braulke, T.20
Mühlhausen, C.21
Backos Donald, S.22
Olsen Christian, A.23
McGuire Peter, J.24
Pletcher Scott, D.25
Lombard David, B.26
Hirschey Matthew, D.27
Zhao, Y.28
more..
-
12
-
-
84883307077
-
Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation
-
Weinert Brian T, Schölz C, Wagner Sebastian A, Iesmantavicius V, Su D, Daniel Jeremy A, Choudhary C, (2013) Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell Rep 4: 842-851.
-
(2013)
Cell Rep
, vol.4
, pp. 842-851
-
-
Weinert Brian, T.1
Schölz, C.2
Wagner Sebastian, A.3
Iesmantavicius, V.4
Su, D.5
Daniel Jeremy, A.6
Choudhary, C.7
-
13
-
-
84890673317
-
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli
-
Colak G, Xie Z, Zhu AY, Dai L, Lu Z, Zhang Y, Wan X, Chen Y, Cha YH, Lin H, Zhao Y, Tan M, (2013) Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Mol Cell Proteomics 12: 3509-3520.
-
(2013)
Mol Cell Proteomics
, vol.12
, pp. 3509-3520
-
-
Colak, G.1
Xie, Z.2
Zhu, A.Y.3
Dai, L.4
Lu, Z.5
Zhang, Y.6
Wan, X.7
Chen, Y.8
Cha, Y.H.9
Lin, H.10
Zhao, Y.11
Tan, M.12
-
14
-
-
35648935529
-
N-Lysine propionylation controls the activity of propionyl-CoA synthetase
-
Garrity J, Gardner JG, Hawse W, Wolberger C, Escalante-Semerena JC, (2007) N-Lysine propionylation controls the activity of propionyl-CoA synthetase. J Biol Chem 282: 30239-30245.
-
(2007)
J Biol Chem
, vol.282
, pp. 30239-30245
-
-
Garrity, J.1
Gardner, J.G.2
Hawse, W.3
Wolberger, C.4
Escalante-Semerena, J.C.5
-
15
-
-
84889636259
-
SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks
-
Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, Mulhern D, Stevens RD, Ilkayeva OR, Newgard CB, Jacobson MP, Hellerstein M, Goetzman ES, Gibson BW, Verdin E, (2013) SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metab 18: 920-933.
-
(2013)
Cell Metab
, vol.18
, pp. 920-933
-
-
Rardin, M.J.1
He, W.2
Nishida, Y.3
Newman, J.C.4
Carrico, C.5
Danielson, S.R.6
Guo, A.7
Gut, P.8
Sahu, A.K.9
Li, B.10
Uppala, R.11
Fitch, M.12
Riiff, T.13
Zhu, L.14
Zhou, J.15
Mulhern, D.16
Stevens, R.D.17
Ilkayeva, O.R.18
Newgard, C.B.19
Jacobson, M.P.20
Hellerstein, M.21
Goetzman, E.S.22
Gibson, B.W.23
Verdin, E.24
more..
-
16
-
-
81055122671
-
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
-
Du J, Zhou Y, Su X, Yu JJ, Khan S, Jiang H, Kim J, Woo J, Kim JH, Choi BH, He B, Chen W, Zhang S, Cerione RA, Auwerx J, Hao Q, Lin H, (2011) Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. Science 334: 806-809.
-
(2011)
Science
, vol.334
, pp. 806-809
-
-
Du, J.1
Zhou, Y.2
Su, X.3
Yu, J.J.4
Khan, S.5
Jiang, H.6
Kim, J.7
Woo, J.8
Kim, J.H.9
Choi, B.H.10
He, B.11
Chen, W.12
Zhang, S.13
Cerione, R.A.14
Auwerx, J.15
Hao, Q.16
Lin, H.17
-
17
-
-
12944283150
-
A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family
-
Smith JS, Brachmann CB, Celic I, Kenna MA, Muhammad S, Starai VJ, Avalos JL, Escalante-Semerena JC, Grubmeyer C, Wolberger C, Boeke JD, (2000) A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family. Proc Natl Acad Sci U S A 97: 6658-6663.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6658-6663
-
-
Smith, J.S.1
Brachmann, C.B.2
Celic, I.3
Kenna, M.A.4
Muhammad, S.5
Starai, V.J.6
Avalos, J.L.7
Escalante-Semerena, J.C.8
Grubmeyer, C.9
Wolberger, C.10
Boeke, J.D.11
-
18
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye RA, (2000) Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273: 793-798.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
19
-
-
72949112693
-
Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation
-
Greiss S, Gartner A, (2009) Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation. Mol Cells 28: 407-415.
-
(2009)
Mol Cells
, vol.28
, pp. 407-415
-
-
Greiss, S.1
Gartner, A.2
-
20
-
-
0027192267
-
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
-
Braunstein M, Rose AB, Holmes SG, Allis CD, Broach JR, (1993) Transcriptional silencing in yeast is associated with reduced nucleosome acetylation. Genes Dev 7: 592-604.
-
(1993)
Genes Dev
, vol.7
, pp. 592-604
-
-
Braunstein, M.1
Rose, A.B.2
Holmes, S.G.3
Allis, C.D.4
Broach, J.R.5
-
21
-
-
77952826169
-
CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY
-
Li R, Gu J, Chen Y-Y, Xiao C-L, Wang L-W, Zhang Z-P, Bi L-J, Wei H-P, Wang X-D, Deng J-Y, Zhang X-E, (2010) CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY. Mol Microbiol 76: 1162-1174.
-
(2010)
Mol Microbiol
, vol.76
, pp. 1162-1174
-
-
Li, R.1
Gu, J.2
Chen, Y.-Y.3
Xiao, C.-L.4
Wang, L.-W.5
Zhang, Z.-P.6
Bi, L.-J.7
Wei, H.-P.8
Wang, X.-D.9
Deng, J.-Y.10
Zhang, X.-E.11
-
22
-
-
0347457075
-
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
-
Starai VJ, Celic I, Cole RN, Boeke JD, Escalante-Semerena JC, (2002) Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science 298: 2390-2392.
-
(2002)
Science
, vol.298
, pp. 2390-2392
-
-
Starai, V.J.1
Celic, I.2
Cole, R.N.3
Boeke, J.D.4
Escalante-Semerena, J.C.5
-
23
-
-
84876921286
-
Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase
-
Zhang Q, Gu J, Gong P, Wang X, Tu S, Bi L, Yu Z, Zhang Z, Cui Z, Wei H, Tao S, Zhang X, (2013) Reversibly acetylated lysine residues play important roles in the enzymatic activity of Escherichia coli N-hydroxyarylamine O-acetyltransferase. FEBS J 280: 1966-1979.
-
(2013)
FEBS J
, vol.280
, pp. 1966-1979
-
-
Zhang, Q.1
Gu, J.2
Gong, P.3
Wang, X.4
Tu, S.5
Bi, L.6
Yu, Z.7
Zhang, Z.8
Cui, Z.9
Wei, H.10
Tao, S.11
Zhang, X.12
-
24
-
-
80051937249
-
Involvement of protein acetylation in glucose-induced transcription of a stress-responsive promoter
-
Lima BP, Antelmann H, Gronau K, Chi BK, Becher D, Brinsmade SR, Wolfe AJ, (2011) Involvement of protein acetylation in glucose-induced transcription of a stress-responsive promoter. Mol Microbiol 81: 1190-1204.
-
(2011)
Mol Microbiol
, vol.81
, pp. 1190-1204
-
-
Lima, B.P.1
Antelmann, H.2
Gronau, K.3
Chi, B.K.4
Becher, D.5
Brinsmade, S.R.6
Wolfe, A.J.7
-
25
-
-
84883304269
-
Acetylation of the response regulator RcsB controls transcription from a small RNA promoter
-
Hu LI, Chi BK, Kuhn ML, Filippova EV, Walker-Peddakotla AJ, Bäsell K, Becher D, Anderson WF, Antelmann H, Wolfe AJ, (2013) Acetylation of the response regulator RcsB controls transcription from a small RNA promoter. J Bacteriol 195: 4174-4186.
-
(2013)
J Bacteriol
, vol.195
, pp. 4174-4186
-
-
Hu, L.I.1
Chi, B.K.2
Kuhn, M.L.3
Filippova, E.V.4
Walker-Peddakotla, A.J.5
Bäsell, K.6
Becher, D.7
Anderson, W.F.8
Antelmann, H.9
Wolfe, A.J.10
-
26
-
-
79251477191
-
Lysine acetylation of a bacterial transcription factor inhibits its DNA-binding activity
-
Thao S, Chen C-S, Zhu H, Escalante-Semerena JC, (2010) Lysine acetylation of a bacterial transcription factor inhibits its DNA-binding activity. PLoS ONE 5: e15123.
-
(2010)
PLoS ONE
, vol.5
, pp. e15123
-
-
Thao, S.1
Chen, C.-S.2
Zhu, H.3
Escalante-Semerena, J.C.4
-
27
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
Michan S, Sinclair D, (2007) Sirtuins in mammals: insights into their biological function. Biochem J 404: 1-13.
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
28
-
-
81855170577
-
The human sirtuin family: Evolutionary divergences and functions
-
Vassilopoulos A, Fritz K, Petersen D, Gius D, (2011) The human sirtuin family: evolutionary divergences and functions. Hum Genomics 5: 485-496.
-
(2011)
Hum Genomics
, vol.5
, pp. 485-496
-
-
Vassilopoulos, A.1
Fritz, K.2
Petersen, D.3
Gius, D.4
-
29
-
-
33745203038
-
The biochemistry of sirtuins
-
Sauve AA, Wolberger C, Schramm VL, Boeke JD, (2006) The biochemistry of sirtuins. Annu Rev Biochem 75: 435-465.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 435-465
-
-
Sauve, A.A.1
Wolberger, C.2
Schramm, V.L.3
Boeke, J.D.4
-
31
-
-
84875881601
-
SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine
-
Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, Du J, Kim R, Ge E, Mostoslavsky R, Hang HC, Hao Q, Lin H, (2013) SIRT6 regulates TNF-alpha secretion through hydrolysis of long-chain fatty acyl lysine. Nature 496: 110-113.
-
(2013)
Nature
, vol.496
, pp. 110-113
-
-
Jiang, H.1
Khan, S.2
Wang, Y.3
Charron, G.4
He, B.5
Sebastian, C.6
Du, J.7
Kim, R.8
Ge, E.9
Mostoslavsky, R.10
Hang, H.C.11
Hao, Q.12
Lin, H.13
-
32
-
-
84862907582
-
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine
-
Zhu AY, Zhou Y, Khan S, Deitsch KW, Hao Q, Lin H, (2011) Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine. ACS Chem Biol 7: 155-159.
-
(2011)
ACS Chem Biol
, vol.7
, pp. 155-159
-
-
Zhu, A.Y.1
Zhou, Y.2
Khan, S.3
Deitsch, K.W.4
Hao, Q.5
Lin, H.6
-
33
-
-
84886686038
-
Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins
-
Feldman JL, Baeza J, Denu JM, (2013) Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins. J Biol Chem 288: 31350-31356.
-
(2013)
J Biol Chem
, vol.288
, pp. 31350-31356
-
-
Feldman, J.L.1
Baeza, J.2
Denu, J.M.3
-
34
-
-
84880791239
-
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
-
Park J, Chen Y, Tishkoff Daniel X, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans Bernadette MM, Skinner Mary E, Lombard David B, Zhao Y, (2013) SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell 50: 919-930.
-
(2013)
Mol Cell
, vol.50
, pp. 919-930
-
-
Park, J.1
Chen, Y.2
Tishkoff Daniel, X.3
Peng, C.4
Tan, M.5
Dai, L.6
Xie, Z.7
Zhang, Y.8
Zwaans Bernadette, M.M.9
Skinner Mary, E.10
Lombard David, B.11
Zhao, Y.12
-
35
-
-
84887412525
-
SIRT5 desuccinylates and activates SOD1 to eliminate ROS
-
Lin Z-F, Xu H-B, Wang J-Y, Lin Q, Ruan Z, Liu F-B, Jin W, Huang H-H, Chen X, (2013) SIRT5 desuccinylates and activates SOD1 to eliminate ROS. Biochem Biophys Res Commun 441: 191-195.
-
(2013)
Biochem Biophys Res Commun
, vol.441
, pp. 191-195
-
-
Lin, Z.-F.1
Xu, H.-B.2
Wang, J.-Y.3
Lin, Q.4
Ruan, Z.5
Liu, F.-B.6
Jin, W.7
Huang, H.-H.8
Chen, X.9
-
36
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF, (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452: 492-496.
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.9
Barrett, J.C.10
Chang, H.Y.11
Bohr, V.A.12
Ried, T.13
Gozani, O.14
Chua, K.F.15
-
37
-
-
84871676013
-
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis
-
Dominy JE Jr, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, Puigserver P, (2012) The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Mol Cell 48: 900-913.
-
(2012)
Mol Cell
, vol.48
, pp. 900-913
-
-
Dominy, Jr.J.E.1
Lee, Y.2
Jedrychowski, M.P.3
Chim, H.4
Jurczak, M.J.5
Camporez, J.P.6
Ruan, H.B.7
Feldman, J.8
Pierce, K.9
Mostoslavsky, R.10
Denu, J.M.11
Clish, C.B.12
Yang, X.13
Shulman, G.I.14
Gygi, S.P.15
Puigserver, P.16
-
38
-
-
0036753953
-
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
-
Avalos JL, Celic I, Muhammad S, Cosgrove MS, Boeke JD, Wolberger C, (2002) Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Mol Cell 10: 523-535.
-
(2002)
Mol Cell
, vol.10
, pp. 523-535
-
-
Avalos, J.L.1
Celic, I.2
Muhammad, S.3
Cosgrove, M.S.4
Boeke, J.D.5
Wolberger, C.6
-
39
-
-
0035917536
-
Crystal structure of a SIR2 homolog-NAD complex
-
Min J, Landry J, Sternglanz R, Xu R-M, (2001) Crystal structure of a SIR2 homolog-NAD complex. Cell 105: 269-279.
-
(2001)
Cell
, vol.105
, pp. 269-279
-
-
Min, J.1
Landry, J.2
Sternglanz, R.3
Xu, R.-M.4
-
40
-
-
1542298916
-
Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Escherichia coli
-
Zhao K, Chai X, Marmorstein R, (2004) Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Escherichia coli. J Mol Biol 337: 731-741.
-
(2004)
J Mol Biol
, vol.337
, pp. 731-741
-
-
Zhao, K.1
Chai, X.2
Marmorstein, R.3
-
41
-
-
15244355745
-
Mechanism of sirtuin inhibition by nicotinamide: Altering the NAD+ cosubstrate specificity of a Sir2 enzyme
-
Avalos JL, Bever KM, Wolberger C, (2005) Mechanism of sirtuin inhibition by nicotinamide: Altering the NAD+ cosubstrate specificity of a Sir2 enzyme. Mol Cell 17: 855-868.
-
(2005)
Mol Cell
, vol.17
, pp. 855-868
-
-
Avalos, J.L.1
Bever, K.M.2
Wolberger, C.3
-
42
-
-
33745119442
-
The structural basis of sirtuin substrate affinity
-
Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C, (2006) The structural basis of sirtuin substrate affinity. Biochemistry 45: 7511-7521.
-
(2006)
Biochemistry
, vol.45
, pp. 7511-7521
-
-
Cosgrove, M.S.1
Bever, K.2
Avalos, J.L.3
Muhammad, S.4
Zhang, X.5
Wolberger, C.6
-
43
-
-
0037072885
-
Structural basis for the NAD-dependent deacetylase mechanism of Sir2
-
Chang JH, Kim HC, Hwang KY, Lee JW, Jackson SP, Bell SD, Cho Y, (2002) Structural basis for the NAD-dependent deacetylase mechanism of Sir2. J Biol Chem 277: 34489-34498.
-
(2002)
J Biol Chem
, vol.277
, pp. 34489-34498
-
-
Chang, J.H.1
Kim, H.C.2
Hwang, K.Y.3
Lee, J.W.4
Jackson, S.P.5
Bell, S.D.6
Cho, Y.7
-
44
-
-
1642297558
-
Structural basis for the mechanism and regulation of Sir2 enzymes
-
Avalos JL, Boeke JD, Wolberger C, (2004) Structural basis for the mechanism and regulation of Sir2 enzymes. Mol Cell 13: 639-648.
-
(2004)
Mol Cell
, vol.13
, pp. 639-648
-
-
Avalos, J.L.1
Boeke, J.D.2
Wolberger, C.3
-
45
-
-
84866552404
-
Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition
-
Fischer F, Gertz M, Suenkel B, Lakshminarasimhan M, Schutkowski M, Steegborn C, (2012) Sirt5 deacylation activities show differential sensitivities to nicotinamide inhibition. PLoS One 7: e45098.
-
(2012)
PLoS One
, vol.7
, pp. e45098
-
-
Fischer, F.1
Gertz, M.2
Suenkel, B.3
Lakshminarasimhan, M.4
Schutkowski, M.5
Steegborn, C.6
-
46
-
-
70450225307
-
Structure-based mechanism of ADP-ribosylation by sirtuins
-
Hawse WF, Wolberger C, (2009) Structure-based mechanism of ADP-ribosylation by sirtuins. J Biol Chem 284: 33654-33661.
-
(2009)
J Biol Chem
, vol.284
, pp. 33654-33661
-
-
Hawse, W.F.1
Wolberger, C.2
-
47
-
-
78650786849
-
Structure of Sir2Tm bound to a propionylated peptide
-
Bheda P, Wang JT, Escalante-Semerena JC, Wolberger C, (2011) Structure of Sir2Tm bound to a propionylated peptide. Protein Sci 20: 131-139.
-
(2011)
Protein Sci
, vol.20
, pp. 131-139
-
-
Bheda, P.1
Wang, J.T.2
Escalante-Semerena, J.C.3
Wolberger, C.4
-
48
-
-
84876715762
-
Crystal structure analysis of human Sirt2 and its ADP-ribose complex
-
Moniot S, Schutkowski M, Steegborn C, (2013) Crystal structure analysis of human Sirt2 and its ADP-ribose complex. J Struct Biol 182: 136-143.
-
(2013)
J Struct Biol
, vol.182
, pp. 136-143
-
-
Moniot, S.1
Schutkowski, M.2
Steegborn, C.3
-
49
-
-
37549067781
-
Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases
-
Smith BC, Denu JM, (2007) Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases. J Biol Chem 282: 37256-37265.
-
(2007)
J Biol Chem
, vol.282
, pp. 37256-37265
-
-
Smith, B.C.1
Denu, J.M.2
-
50
-
-
84904872156
-
The growing landscape of lysine acetylation links metabolism and cell signalling
-
Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M, (2014) The growing landscape of lysine acetylation links metabolism and cell signalling. Nat Rev Mol Cell Biol 15: 536-550.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 536-550
-
-
Choudhary, C.1
Weinert, B.T.2
Nishida, Y.3
Verdin, E.4
Mann, M.5
-
51
-
-
0036279988
-
SIR2 family of NAD+-dependent protein deacetylases
-
Smith JS, Avalos J, Celic I, Muhammad S, Wolberger C, Boeke JD, (2002) SIR2 family of NAD+-dependent protein deacetylases. Methods Enzymol 353: 282-300.
-
(2002)
Methods Enzymol
, vol.353
, pp. 282-300
-
-
Smith, J.S.1
Avalos, J.2
Celic, I.3
Muhammad, S.4
Wolberger, C.5
Boeke, J.D.6
-
52
-
-
14844294424
-
Protein production by auto-induction in high-density shaking cultures
-
Studier FW, (2005) Protein production by auto-induction in high-density shaking cultures. Protein Express Purif 41: 207-234.
-
(2005)
Protein Express Purif
, vol.41
, pp. 207-234
-
-
Studier, F.W.1
-
53
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Carter C.W. Jr, Ed. New York: Academic Press
-
Otwinowski Z, Minor W, Processing of X-ray diffraction data collected in oscillation mode. In:, Carter CW, Jr, Ed. (1997) Methods enzymol. New York: Academic Press, pp 307-326.
-
(1997)
Methods Enzymol
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
54
-
-
74549194551
-
Molecular replacement with MOLREP
-
Vagin A, Teplyakov A, (2010) Molecular replacement with MOLREP. Acta Cryst D66: 22-25.
-
(2010)
Acta Cryst
, vol.D66
, pp. 22-25
-
-
Vagin, A.1
Teplyakov, A.2
-
55
-
-
0000560808
-
MOLREP: An automated program for molecular replacement
-
Vagin A, Teplyakov A, (1997) MOLREP: An automated program for molecular replacement. J Appl Cryst 30: 1022-1025.
-
(1997)
J Appl Cryst
, vol.30
, pp. 1022-1025
-
-
Vagin, A.1
Teplyakov, A.2
-
56
-
-
79953737180
-
Overview of the CCP4 suite and current developments
-
Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, Evans PR, Keegan RM, Krissinel EB, Leslie AGW, McCoy A, McNicholas SJ, Murshudov GN, Pannu NS, Potterton EA, Powell HR, Read RJ, Vagin A, Wilson KS, (2011) Overview of the CCP4 suite and current developments. Acta Cryst D67: 235-242.
-
(2011)
Acta Cryst
, vol.D67
, pp. 235-242
-
-
Winn, M.D.1
Ballard, C.C.2
Cowtan, K.D.3
Dodson, E.J.4
Emsley, P.5
Evans, P.R.6
Keegan, R.M.7
Krissinel, E.B.8
Leslie, A.G.W.9
McCoy, A.10
McNicholas, S.J.11
Murshudov, G.N.12
Pannu, N.S.13
Potterton, E.A.14
Powell, H.R.15
Read, R.J.16
Vagin, A.17
Wilson, K.S.18
-
57
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley P, Cowtan K, (2004) Coot: model-building tools for molecular graphics. Acta Cryst D60: 2126-2132.
-
(2004)
Acta Cryst
, vol.D60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
58
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov GN, Vagin AA, Dodson EJ, (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Cryst D53: 240-255.
-
(1997)
Acta Cryst
, vol.D53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
59
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams PD, Afonine PV, Bunkoczi G, Chen VB, Davis IW, Echols N, Headd JJ, Hung L-W, Kapral GJ, Grosse-Kunstleve RW, McCoy AJ, Moriarty NW, Oeffner R, Read RJ, Richardson DC, Richardson JS, Terwilliger TC, Zwart PH, (2010) PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Cryst D66: 213-221.
-
(2010)
Acta Cryst
, vol.D66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkoczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.-W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
McCoy, A.J.11
Moriarty, N.W.12
Oeffner, R.13
Read, R.J.14
Richardson, D.C.15
Richardson, J.S.16
Terwilliger, T.C.17
Zwart, P.H.18
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