Complete regression of xenograft tumors upon targeted delivery of paclitaxel via ∏ - ∏ stacking stabilized polymeric micelles

ACS Nano

Volumn 9, Issue 4, 2015, Pages 3740-3752

  Shi, Yang ^a   Van Der Meel, Roy ^b   Theek, Benjamin ^c   Oude Blenke, Erik ^a   Pieters, Ebel H E ^a   Fens, Marcel H A M ^b   Ehling, Josef ^c   Schiffelers, Raymond M ^b   Storm, Gert ^a,d   Van Nostrum, Cornelus F ^a   Lammers, Twan ^a,c,d   Hennink, Wim E ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^d UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

drug targeting; nanomedicine; paclitaxel; polymeric micelles; stacking

Indexed keywords

AROMATIC POLYMERS; BIOLOGICAL MATERIALS; BLOCK COPOLYMERS; CROSSLINKING; DRUG PRODUCTS; FUNCTIONAL POLYMERS; HYDROPHOBICITY; INFRARED DEVICES; LOADING; MEDICAL NANOTECHNOLOGY; MICELLES; MOTION PICTURE EXPERTS GROUP STANDARDS; PATIENT TREATMENT; POLYETHYLENE GLYCOLS; TUMORS;

CHEMICAL CROSS-LINKING; CIRCULATION KINETICS; DRUG-TARGETING; METHOXYPOLYETHYLENE GLYCOL; PACLITAXEL; POLYMERIC MICELLE; STACKING INTERACTION; TUMOR TARGETED DELIVERY;

POLYMERS;

ANTINEOPLASTIC AGENT; DRUG CARRIER; HYDROXYPROPYL METHACRYLATE; MACROGOL DERIVATIVE; METHACRYLIC ACID DERIVATIVE; MICELLE; PACLITAXEL; POLYMER;

ANIMAL; CARCINOMA, SQUAMOUS CELL; CHEMISTRY; DRUG SCREENING; DRUG STABILITY; FEMALE; HUMAN; KINETICS; MAMMARY NEOPLASMS, EXPERIMENTAL; METABOLISM; MICELLE; MOUSE; MULTIMODAL IMAGING; PATHOLOGY; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DRUG CARRIERS; DRUG STABILITY; FEMALE; HUMANS; KINETICS; MAMMARY NEOPLASMS, EXPERIMENTAL; METHACRYLATES; MICE; MICELLES; MULTIMODAL IMAGING; PACLITAXEL; POLYETHYLENE GLYCOLS; POLYMERS; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84928964261     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b00929     Document Type: Article

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