Functional alginate nanoparticles for efficient intracellular release of doxorubicin and hepatoma carcinoma cell targeting therapy

International Journal of Pharmaceutics

Volumn 451, Issue 1-2, 2013, Pages 1-11

  Guo, Hua ^a   Lai, Quanyong ^a   Wang, Wei ^a   Wu, Yukun ^a   Zhang, Chuangnian ^a   Liu, Yuan ^a   Yuan, Zhi ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

Antitumor; Hepatoma targeted; Intracellular drug release; pH sensitive

Indexed keywords

ALGINIC ACID; ANTINEOPLASTIC AGENT; DOXORUBICIN; GLYCYRRHETINIC ACID; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CANCER INHIBITION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG RELEASE; ENDOSOME; FEMALE; HUMAN; HUMAN CELL; LIGHT SCATTERING; LIVER CELL CARCINOMA; LYSOSOME; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; ZETA POTENTIAL;

ALGINATES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; AREA UNDER CURVE; CARCINOMA, HEPATOCELLULAR; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; GLUCURONIC ACID; HALF-LIFE; HEP G2 CELLS; HEXURONIC ACIDS; HUMANS; HYDROGEN-ION CONCENTRATION; LIVER NEOPLASMS; MICE; MICROSCOPY, CONFOCAL; NANOPARTICLES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84877842747     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.04.025     Document Type: Article

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