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Volumn 125, Issue , 2015, Pages 82-89

RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells

Author keywords

Dendrimers; Doxorubicin; Host guest interaction; RGD peptide; Targeted cancer therapy

Indexed keywords

ACETYLATION; AMINO ACIDS; CELLS; CYTOLOGY; DENDRIMERS; DISEASES; DRUG DELIVERY; DRUG INTERACTIONS; ENCAPSULATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOLOGY; PEPTIDES;

EID: 84912079021     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2014.11.004     Document Type: Article
Times cited : (105)

References (66)
  • 2
    • 79960326680 scopus 로고    scopus 로고
    • Targeted delivery of doxorubicin into cancer cells using a folic acid-dendrimer conjugate
    • Wang Y., Cao X., Guo R., Shen M., Zhang M., Zhu M., Shi X. Targeted delivery of doxorubicin into cancer cells using a folic acid-dendrimer conjugate. Polym. Chem. 2011, 2:1754-1760.
    • (2011) Polym. Chem. , vol.2 , pp. 1754-1760
    • Wang, Y.1    Cao, X.2    Guo, R.3    Shen, M.4    Zhang, M.5    Zhu, M.6    Shi, X.7
  • 3
    • 79951851197 scopus 로고    scopus 로고
    • Encapsulation of 2-methoxyestradiol within multifunctional poly(amidoamine) dendrimers for targeted cancer therapy
    • Wang Y., Guo R., Cao X., Shen M., Shi X. Encapsulation of 2-methoxyestradiol within multifunctional poly(amidoamine) dendrimers for targeted cancer therapy. Biomaterials 2011, 32:3322-3329.
    • (2011) Biomaterials , vol.32 , pp. 3322-3329
    • Wang, Y.1    Guo, R.2    Cao, X.3    Shen, M.4    Shi, X.5
  • 4
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • Panyam J., Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv. Drug Deliv. Rev. 2003, 55:329-347.
    • (2003) Adv. Drug Deliv. Rev. , vol.55 , pp. 329-347
    • Panyam, J.1    Labhasetwar, V.2
  • 5
    • 84885170516 scopus 로고    scopus 로고
    • Dendrimer-entrapped gold nanoparticles modified with folic acid for targeted gene delivery applications
    • Xiao T., Hou W., Cao X., Wen S., Shen M., Shi X. Dendrimer-entrapped gold nanoparticles modified with folic acid for targeted gene delivery applications. Biomater. Sci. 2013, 1:1172-1180.
    • (2013) Biomater. Sci. , vol.1 , pp. 1172-1180
    • Xiao, T.1    Hou, W.2    Cao, X.3    Wen, S.4    Shen, M.5    Shi, X.6
  • 8
    • 84877277795 scopus 로고    scopus 로고
    • Targeted tumor computed tomography imaging using low-generation dendrimer-stabilized gold nanoparticles
    • Liu H., Xu Y., Wen S., Chen Q., Zheng L., Shen M., Zhao J., Zhang G., Shi X. Targeted tumor computed tomography imaging using low-generation dendrimer-stabilized gold nanoparticles. Chem. Eur. J. 2013, 19:6409-6416.
    • (2013) Chem. Eur. J. , vol.19 , pp. 6409-6416
    • Liu, H.1    Xu, Y.2    Wen, S.3    Chen, Q.4    Zheng, L.5    Shen, M.6    Zhao, J.7    Zhang, G.8    Shi, X.9
  • 9
    • 81355122670 scopus 로고    scopus 로고
    • PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography
    • Peng C., Zheng L., Chen Q., Shen M., Guo R., Wang H., Cao X., Zhang G., Shi X. PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography. Biomaterials 2012, 33:1107-1119.
    • (2012) Biomaterials , vol.33 , pp. 1107-1119
    • Peng, C.1    Zheng, L.2    Chen, Q.3    Shen, M.4    Guo, R.5    Wang, H.6    Cao, X.7    Zhang, G.8    Shi, X.9
  • 10
    • 54949085745 scopus 로고    scopus 로고
    • Dendrimer-functionalized shell-crosslinked iron oxide nanoparticles for in-vivo magnetic resonance imaging of tumors
    • Shi X., Wang S.H., Swanson S.D., Ge S., Cao Z., Van Antwerp M.E., Landmark K.J., Baker J.R. Dendrimer-functionalized shell-crosslinked iron oxide nanoparticles for in-vivo magnetic resonance imaging of tumors. Adv. Mater. 2008, 20:1671-1678.
    • (2008) Adv. Mater. , vol.20 , pp. 1671-1678
    • Shi, X.1    Wang, S.H.2    Swanson, S.D.3    Ge, S.4    Cao, Z.5    Van Antwerp, M.E.6    Landmark, K.J.7    Baker, J.R.8
  • 11
    • 84878791758 scopus 로고    scopus 로고
    • Targeted cancer cell inhibition using multifunctional dendrimer-entrapped gold nanoparticles
    • Zheng L., Zhu J., Shen M., Chen X., Baker J.R., Wang S.H., Zhang G., Shi X. Targeted cancer cell inhibition using multifunctional dendrimer-entrapped gold nanoparticles. Med. Chem. Commun. 2013, 4:1001-1005.
    • (2013) Med. Chem. Commun. , vol.4 , pp. 1001-1005
    • Zheng, L.1    Zhu, J.2    Shen, M.3    Chen, X.4    Baker, J.R.5    Wang, S.H.6    Zhang, G.7    Shi, X.8
  • 12
    • 84902532853 scopus 로고    scopus 로고
    • Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles
    • Zhu J., Zheng L., Wen S., Tang Y., Shen M., Zhang G., Shi X. Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles. Biomaterials 2014, 35:7635-7646.
    • (2014) Biomaterials , vol.35 , pp. 7635-7646
    • Zhu, J.1    Zheng, L.2    Wen, S.3    Tang, Y.4    Shen, M.5    Zhang, G.6    Shi, X.7
  • 13
    • 84892572815 scopus 로고    scopus 로고
    • Tungsten oxide nanorods: an efficient nanoplatform for tumor CT imaging and photothermal therapy
    • Zhou Z., Kong B., Yu C., Shi X., Wang M., Liu W., Sun Y., Zhang Y., Yang H., Yang S. Tungsten oxide nanorods: an efficient nanoplatform for tumor CT imaging and photothermal therapy. Sci. Rep. 2014, 4:3653.
    • (2014) Sci. Rep. , vol.4 , pp. 3653
    • Zhou, Z.1    Kong, B.2    Yu, C.3    Shi, X.4    Wang, M.5    Liu, W.6    Sun, Y.7    Zhang, Y.8    Yang, H.9    Yang, S.10
  • 14
    • 84906237305 scopus 로고    scopus 로고
    • Enhanced in vivo antitumor efficacy of doxorubicin encapsulated within laponite nanodisks
    • Li K., Wang S., Wen S., Tang Y., Li J., Shi X., Zhao Q. Enhanced in vivo antitumor efficacy of doxorubicin encapsulated within laponite nanodisks. ACS Appl. Mater. Interfaces 2014, 6:12328-12334.
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , pp. 12328-12334
    • Li, K.1    Wang, S.2    Wen, S.3    Tang, Y.4    Li, J.5    Shi, X.6    Zhao, Q.7
  • 15
    • 84863913286 scopus 로고    scopus 로고
    • Multifunctional dendrimer/combretastatin A4 inclusion complexes enable in vitro targeted cancer therapy
    • Zhang M., Guo R., Wang Y., Cao X., Shen M., Shi X. Multifunctional dendrimer/combretastatin A4 inclusion complexes enable in vitro targeted cancer therapy. Int. J. Nanomed. 2011, 6:2337-2349.
    • (2011) Int. J. Nanomed. , vol.6 , pp. 2337-2349
    • Zhang, M.1    Guo, R.2    Wang, Y.3    Cao, X.4    Shen, M.5    Shi, X.6
  • 16
    • 84903271234 scopus 로고    scopus 로고
    • Multifunctional dendrimers modified with alpha-tocopheryl succinate for targeted cancer therapy
    • Zheng Y., Fu F., Zhang M., Shen M., Zhu M., Shi X. Multifunctional dendrimers modified with alpha-tocopheryl succinate for targeted cancer therapy. Med. Chem. Commun. 2014, 5:879-885.
    • (2014) Med. Chem. Commun. , vol.5 , pp. 879-885
    • Zheng, Y.1    Fu, F.2    Zhang, M.3    Shen, M.4    Zhu, M.5    Shi, X.6
  • 17
    • 33645691940 scopus 로고    scopus 로고
    • Engineered nanoparticles as precise drug delivery systems
    • Yih T., Al-Fandi M. Engineered nanoparticles as precise drug delivery systems. J. Cell. Biochem. 2006, 97:1184-1190.
    • (2006) J. Cell. Biochem. , vol.97 , pp. 1184-1190
    • Yih, T.1    Al-Fandi, M.2
  • 18
    • 0242410776 scopus 로고    scopus 로고
    • Drug delivery to resistant tumors: the potential of poly(alkyl cyanoacrylate) nanoparticles
    • Vauthier C., Dubernet C., Chauvierre C., Brigger I., Couvreur P. Drug delivery to resistant tumors: the potential of poly(alkyl cyanoacrylate) nanoparticles. J. Control. Rel. 2003, 93:151-160.
    • (2003) J. Control. Rel. , vol.93 , pp. 151-160
    • Vauthier, C.1    Dubernet, C.2    Chauvierre, C.3    Brigger, I.4    Couvreur, P.5
  • 19
    • 84908101844 scopus 로고    scopus 로고
    • PEGylated dendritic diaminocyclohexyl-platinum (II) conjugates as pH-responsive drug delivery vehicles with enhanced tumor accumulation and antitumor efficacy
    • Pan D., Guo C., Luo K., Yi Q., Gu Z. PEGylated dendritic diaminocyclohexyl-platinum (II) conjugates as pH-responsive drug delivery vehicles with enhanced tumor accumulation and antitumor efficacy. Biomaterials 2014, 35:10080-10092.
    • (2014) Biomaterials , vol.35 , pp. 10080-10092
    • Pan, D.1    Guo, C.2    Luo, K.3    Yi, Q.4    Gu, Z.5
  • 20
    • 84872395372 scopus 로고    scopus 로고
    • Dendronized heparin-doxorubicin conjugate based nanoparticle as pH-responsive drug delivery system for cancer therapy
    • She W., Li N., Luo K., Guo C., Wang G., Geng Y., Gu Z. Dendronized heparin-doxorubicin conjugate based nanoparticle as pH-responsive drug delivery system for cancer therapy. Biomaterials 2013, 34:2252-2264.
    • (2013) Biomaterials , vol.34 , pp. 2252-2264
    • She, W.1    Li, N.2    Luo, K.3    Guo, C.4    Wang, G.5    Geng, Y.6    Gu, Z.7
  • 21
    • 84870714279 scopus 로고    scopus 로고
    • The potential of self-assembled, pH-responsive nanoparticles of mPEGylated peptide dendron-doxorubicin conjugates for cancer therapy
    • She W., Luo K., Zhang C., Wang G., Geng Y., Li L., He B., Gu Z. The potential of self-assembled, pH-responsive nanoparticles of mPEGylated peptide dendron-doxorubicin conjugates for cancer therapy. Biomaterials 2013, 34:1613-1623.
    • (2013) Biomaterials , vol.34 , pp. 1613-1623
    • She, W.1    Luo, K.2    Zhang, C.3    Wang, G.4    Geng, Y.5    Li, L.6    He, B.7    Gu, Z.8
  • 22
    • 84855824016 scopus 로고    scopus 로고
    • Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging
    • Parveen S., Misra R., Sahoo S.K. Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging. Nanomed.-Nanotechnol. Biol. Med. 2012, 8:147-166.
    • (2012) Nanomed.-Nanotechnol. Biol. Med. , vol.8 , pp. 147-166
    • Parveen, S.1    Misra, R.2    Sahoo, S.K.3
  • 23
    • 33847017288 scopus 로고    scopus 로고
    • Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging
    • Tomalia D., Reyna L., Svenson S. Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem. Soc. Trans. 2007, 35:61-67.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 61-67
    • Tomalia, D.1    Reyna, L.2    Svenson, S.3
  • 24
    • 24944531237 scopus 로고    scopus 로고
    • Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy
    • Majoros I.J., Thomas T.P., Mehta C.B., Baker J.R. Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy. J. Med. Chem. 2005, 48:5892-5899.
    • (2005) J. Med. Chem. , vol.48 , pp. 5892-5899
    • Majoros, I.J.1    Thomas, T.P.2    Mehta, C.B.3    Baker, J.R.4
  • 25
    • 84881429200 scopus 로고    scopus 로고
    • Dendrimer-based nanodevices for targeted drug delivery applications
    • Zhu J., Shi X. Dendrimer-based nanodevices for targeted drug delivery applications. J. Mater. Chem. B 2013, 1:4199-4211.
    • (2013) J. Mater. Chem. B , vol.1 , pp. 4199-4211
    • Zhu, J.1    Shi, X.2
  • 29
    • 39749200864 scopus 로고    scopus 로고
    • Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability
    • Dhanikula R.S., Argaw A., Bouchard J.-F., Hildgen P. Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability. Mol. Pharmaceutics 2008, 5:105-116.
    • (2008) Mol. Pharmaceutics , vol.5 , pp. 105-116
    • Dhanikula, R.S.1    Argaw, A.2    Bouchard, J.-F.3    Hildgen, P.4
  • 30
    • 34547171711 scopus 로고    scopus 로고
    • Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging
    • Shi X., Wang S., Meshinchi S., Van Antwerp M.E., Bi X., Lee I., Baker J.R. Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging. Small 2007, 3:1245-1252.
    • (2007) Small , vol.3 , pp. 1245-1252
    • Shi, X.1    Wang, S.2    Meshinchi, S.3    Van Antwerp, M.E.4    Bi, X.5    Lee, I.6    Baker, J.R.7
  • 31
    • 33644593095 scopus 로고    scopus 로고
    • PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality
    • Majoros I.J., Myc A., Thomas T., Mehta C.B., Baker J.R. PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules 2006, 7:572-579.
    • (2006) Biomacromolecules , vol.7 , pp. 572-579
    • Majoros, I.J.1    Myc, A.2    Thomas, T.3    Mehta, C.B.4    Baker, J.R.5
  • 32
    • 67650500319 scopus 로고    scopus 로고
    • Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging
    • Shi X., Wang S.H., Shen M., Antwerp M.E., Chen X., Li C., Petersen E.J., Huang Q., Weber W.J., Baker J.R. Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging. Biomacromolecules 2009, 10:1744-1750.
    • (2009) Biomacromolecules , vol.10 , pp. 1744-1750
    • Shi, X.1    Wang, S.H.2    Shen, M.3    Antwerp, M.E.4    Chen, X.5    Li, C.6    Petersen, E.J.7    Huang, Q.8    Weber, W.J.9    Baker, J.R.10
  • 33
    • 35549009338 scopus 로고    scopus 로고
    • Synthesis, characterization, and intracellular uptake of carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles
    • Shi X., Thomas T.P., Myc L.A., Kotlyar A., Baker J.R. Synthesis, characterization, and intracellular uptake of carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles. Phys. Chem. Chem. Phys. 2007, 9:5712-5720.
    • (2007) Phys. Chem. Chem. Phys. , vol.9 , pp. 5712-5720
    • Shi, X.1    Thomas, T.P.2    Myc, L.A.3    Kotlyar, A.4    Baker, J.R.5
  • 34
    • 4043103282 scopus 로고    scopus 로고
    • Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery
    • Chen H.-T., Neerman M.F., Parrish A.R., Simanek E.E. Cytotoxicity, hemolysis, and acute in vivo toxicity of dendrimers based on melamine, candidate vehicles for drug delivery. J. Am. Chem. Soc. 2004, 126:10044-10048.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 10044-10048
    • Chen, H.-T.1    Neerman, M.F.2    Parrish, A.R.3    Simanek, E.E.4
  • 35
    • 50249150791 scopus 로고    scopus 로고
    • Systematic investigation of polyamidoamine dendrimers surface-modified with poly(ethylene glycol) for drug delivery applications: synthesis, characterization, and evaluation of cytotoxicity
    • Kim Y., Klutz A.M., Jacobson K.A. Systematic investigation of polyamidoamine dendrimers surface-modified with poly(ethylene glycol) for drug delivery applications: synthesis, characterization, and evaluation of cytotoxicity. Bioconjugate Chem. 2008, 19:1660-1672.
    • (2008) Bioconjugate Chem. , vol.19 , pp. 1660-1672
    • Kim, Y.1    Klutz, A.M.2    Jacobson, K.A.3
  • 36
    • 84897587370 scopus 로고    scopus 로고
    • Antitumor efficacy of doxorubicin encapsulated within PEGylated poly(amidoamine) dendrimers
    • Liao H., Liu H., Li Y., Zhang M., Tomás H., Shen M., Shi X. Antitumor efficacy of doxorubicin encapsulated within PEGylated poly(amidoamine) dendrimers. J. Appl. Polym. Sci. 2014, 131:40358-40368.
    • (2014) J. Appl. Polym. Sci. , vol.131 , pp. 40358-40368
    • Liao, H.1    Liu, H.2    Li, Y.3    Zhang, M.4    Tomás, H.5    Shen, M.6    Shi, X.7
  • 37
    • 84898666018 scopus 로고    scopus 로고
    • Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications
    • Liu H., Wang H., Xu Y., Shen M., Zhao J., Zhang G., Shi X. Synthesis of PEGylated low generation dendrimer-entrapped gold nanoparticles for CT imaging applications. Nanoscale 2014, 6:4521-4526.
    • (2014) Nanoscale , vol.6 , pp. 4521-4526
    • Liu, H.1    Wang, H.2    Xu, Y.3    Shen, M.4    Zhao, J.5    Zhang, G.6    Shi, X.7
  • 38
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • Gordon A.N., Fleagle J.T., Guthrie D., Parkin D.E., Gore M.E., Lacave A.J. Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J. Clin. Oncol. 2001, 19:3312-3322.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3    Parkin, D.E.4    Gore, M.E.5    Lacave, A.J.6
  • 40
    • 0029005580 scopus 로고
    • Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
    • Santoro A., Tursz T., Mouridsen H., Verweij J., Steward W., Somers R., Buesa J., Casali P., Spooner D., Rankin E. Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J. Clin. Oncol. 1995, 13:1537-1545.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1537-1545
    • Santoro, A.1    Tursz, T.2    Mouridsen, H.3    Verweij, J.4    Steward, W.5    Somers, R.6    Buesa, J.7    Casali, P.8    Spooner, D.9    Rankin, E.10
  • 41
    • 72149091705 scopus 로고    scopus 로고
    • Partly PEGylated polyamidoamine dendrimer for tumor-selective targeting of doxorubicin: the effects of PEGylation degree and drug conjugation style
    • Zhu S., Hong M., Tang G., Qian L., Lin J., Jiang Y., Pei Y. Partly PEGylated polyamidoamine dendrimer for tumor-selective targeting of doxorubicin: the effects of PEGylation degree and drug conjugation style. Biomaterials 2010, 31:1360-1371.
    • (2010) Biomaterials , vol.31 , pp. 1360-1371
    • Zhu, S.1    Hong, M.2    Tang, G.3    Qian, L.4    Lin, J.5    Jiang, Y.6    Pei, Y.7
  • 42
    • 84894086215 scopus 로고    scopus 로고
    • Impact of dendrimer surface functional groups on the release of doxorubicin from dendrimer carriers
    • Zhang M., Guo R., Kéri M., Bányai I., Zheng Y., Cao M., Cao X., Shi X. Impact of dendrimer surface functional groups on the release of doxorubicin from dendrimer carriers. J. Phys. Chem. B 2014, 118:1696-1706.
    • (2014) J. Phys. Chem. B , vol.118 , pp. 1696-1706
    • Zhang, M.1    Guo, R.2    Kéri, M.3    Bányai, I.4    Zheng, Y.5    Cao, M.6    Cao, X.7    Shi, X.8
  • 43
    • 77950344697 scopus 로고    scopus 로고
    • Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate
    • Choi S.K., Thomas T., Li M.-H., Kotlyar A., Desai A., Baker J.R. Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem. Commun. 2010, 46:2632-2634.
    • (2010) Chem. Commun. , vol.46 , pp. 2632-2634
    • Choi, S.K.1    Thomas, T.2    Li, M.-H.3    Kotlyar, A.4    Desai, A.5    Baker, J.R.6
  • 44
    • 84923256514 scopus 로고    scopus 로고
    • Amphiphilic peptide dendritic copolymer-doxorubicin nanoscale conjugate self-assembled to enzyme-responsive anti-cancer agent
    • Li N., Li N., Yi Q., Luo K., Guo C., Pan D., Gu Z. Amphiphilic peptide dendritic copolymer-doxorubicin nanoscale conjugate self-assembled to enzyme-responsive anti-cancer agent. Biomaterials 2014, 35:9529-9545.
    • (2014) Biomaterials , vol.35 , pp. 9529-9545
    • Li, N.1    Li, N.2    Yi, Q.3    Luo, K.4    Guo, C.5    Pan, D.6    Gu, Z.7
  • 45
    • 84906261173 scopus 로고    scopus 로고
    • Dendrimer-doxorubicin conjugate as enzyme-sensitive and polymeric nanoscale drug delivery vehicle for ovarian cancer therapy
    • Zhang C., Pan D., Luo K., Li N., Guo C., Zheng X., Gu Z. Dendrimer-doxorubicin conjugate as enzyme-sensitive and polymeric nanoscale drug delivery vehicle for ovarian cancer therapy. Polym. Chem. 2014, 5:5227-5235.
    • (2014) Polym. Chem. , vol.5 , pp. 5227-5235
    • Zhang, C.1    Pan, D.2    Luo, K.3    Li, N.4    Guo, C.5    Zheng, X.6    Gu, Z.7
  • 46
    • 84906076240 scopus 로고    scopus 로고
    • Peptide dendrimer-doxorubicin conjugate-based nanoparticle as an enzyme-responsive drug delivery system for cancer therapy
    • Zhang C., Pan D., Luo K., She W., Guo C., Yang Y., Gu Z. Peptide dendrimer-doxorubicin conjugate-based nanoparticle as an enzyme-responsive drug delivery system for cancer therapy. Adv. Healthcare Mater. 2014, 3:1299-1308.
    • (2014) Adv. Healthcare Mater. , vol.3 , pp. 1299-1308
    • Zhang, C.1    Pan, D.2    Luo, K.3    She, W.4    Guo, C.5    Yang, Y.6    Gu, Z.7
  • 47
    • 0037433811 scopus 로고    scopus 로고
    • A PEGylated dendritic nanoparticulate carrier of fluorouracil
    • Bhadra D., Bhadra S., Jain S., Jain N. A PEGylated dendritic nanoparticulate carrier of fluorouracil. Int. J. Pharm. 2003, 257:111-124.
    • (2003) Int. J. Pharm. , vol.257 , pp. 111-124
    • Bhadra, D.1    Bhadra, S.2    Jain, S.3    Jain, N.4
  • 48
    • 77952866818 scopus 로고    scopus 로고
    • Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers
    • Shi X., Lee I., Chen X., Shen M., Xiao S., Zhu M., Baker J.R., Wang S.H. Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers. Soft Matter 2010, 6:2539-2545.
    • (2010) Soft Matter , vol.6 , pp. 2539-2545
    • Shi, X.1    Lee, I.2    Chen, X.3    Shen, M.4    Xiao, S.5    Zhu, M.6    Baker, J.R.7    Wang, S.H.8
  • 50
    • 81355138967 scopus 로고    scopus 로고
    • Polyethylene glycol-conjugated hyaluronic acid-ceramide self-assembled nanoparticles for targeted delivery of doxorubicin
    • Cho H.-J., Yoon I.-S., Yoon H.Y., Koo H., Jin Y.-J., Ko S.-H., Shim J.-S., Kim K., Kwon I.C., Kim D.-D. Polyethylene glycol-conjugated hyaluronic acid-ceramide self-assembled nanoparticles for targeted delivery of doxorubicin. Biomaterials 2012, 33:1190-1200.
    • (2012) Biomaterials , vol.33 , pp. 1190-1200
    • Cho, H.-J.1    Yoon, I.-S.2    Yoon, H.Y.3    Koo, H.4    Jin, Y.-J.5    Ko, S.-H.6    Shim, J.-S.7    Kim, K.8    Kwon, I.C.9    Kim, D.-D.10
  • 51
    • 0027950222 scopus 로고
    • Boronated starburst dendrimer-monoclonal antibody immunoconjugates: evaluation as a potential delivery system for neutron capture therapy
    • Barth R.F., Adams D.M., Soloway A.H., Alam F., Darby M.V. Boronated starburst dendrimer-monoclonal antibody immunoconjugates: evaluation as a potential delivery system for neutron capture therapy. Bioconjugate Chem. 1994, 5:58-66.
    • (1994) Bioconjugate Chem. , vol.5 , pp. 58-66
    • Barth, R.F.1    Adams, D.M.2    Soloway, A.H.3    Alam, F.4    Darby, M.V.5
  • 52
    • 33847751474 scopus 로고    scopus 로고
    • Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1, 3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes
    • Dijkgraaf I., Rijnders A.Y., Soede A., Dechesne A.C., van Esse G.W., Brouwer A.J., Corstens F.H., Boerman O.C., Rijkers D.T., Liskamp R.M. Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1, 3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes. Org. Biomol. Chem. 2007, 5:935-944.
    • (2007) Org. Biomol. Chem. , vol.5 , pp. 935-944
    • Dijkgraaf, I.1    Rijnders, A.Y.2    Soede, A.3    Dechesne, A.C.4    van Esse, G.W.5    Brouwer, A.J.6    Corstens, F.H.7    Boerman, O.C.8    Rijkers, D.T.9    Liskamp, R.M.10
  • 53
    • 78649444101 scopus 로고    scopus 로고
    • Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer
    • Han L., Huang R., Li J., Liu S., Huang S., Jiang C. Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer. Biomaterials 2011, 32:1242-1252.
    • (2011) Biomaterials , vol.32 , pp. 1242-1252
    • Han, L.1    Huang, R.2    Li, J.3    Liu, S.4    Huang, S.5    Jiang, C.6
  • 54
    • 36849071505 scopus 로고    scopus 로고
    • Synthetic PAMAM-RGD conjugates target and bind To odontoblast-like MDPC 23 cells and the predentin in tooth organ cultures
    • Hill E., Shukla R., Park S.S., Baker J.R. Synthetic PAMAM-RGD conjugates target and bind To odontoblast-like MDPC 23 cells and the predentin in tooth organ cultures. Bioconjugate Chem. 2007, 18:1756-1762.
    • (2007) Bioconjugate Chem. , vol.18 , pp. 1756-1762
    • Hill, E.1    Shukla, R.2    Park, S.S.3    Baker, J.R.4
  • 55
    • 67349184241 scopus 로고    scopus 로고
    • Tumor microvasculature targeting with dendrimer-entrapped gold nanoparticles
    • Shukla R., Hill E., Shi X., Kim J., Muniz M.C., Sun K., Baker J.R. Tumor microvasculature targeting with dendrimer-entrapped gold nanoparticles. Soft Matter 2008, 4:2160-2163.
    • (2008) Soft Matter , vol.4 , pp. 2160-2163
    • Shukla, R.1    Hill, E.2    Shi, X.3    Kim, J.4    Muniz, M.C.5    Sun, K.6    Baker, J.R.7
  • 56
    • 79953061635 scopus 로고    scopus 로고
    • RGD-modified PEG-PAMAM-DOX conjugate: in vitro and in vivo targeting to both tumor neovascular endothelial cells and tumor cells
    • Zhu S., Qian L., Hong M., Zhang L., Pei Y., Jiang Y. RGD-modified PEG-PAMAM-DOX conjugate: in vitro and in vivo targeting to both tumor neovascular endothelial cells and tumor cells. Adv. Mater. 2011, 23:H84-H89.
    • (2011) Adv. Mater. , vol.23 , pp. H84-H89
    • Zhu, S.1    Qian, L.2    Hong, M.3    Zhang, L.4    Pei, Y.5    Jiang, Y.6
  • 57
    • 79951658350 scopus 로고    scopus 로고
    • Gene delivery into mesenchymal stem cells: a biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers
    • Pandita D., Santos J.L., Rodrigues J., Pêgo A.P., Granja P.L., Tomás H. Gene delivery into mesenchymal stem cells: a biomimetic approach using RGD nanoclusters based on poly(amidoamine) dendrimers. Biomacromolecules 2011, 12:472-481.
    • (2011) Biomacromolecules , vol.12 , pp. 472-481
    • Pandita, D.1    Santos, J.L.2    Rodrigues, J.3    Pêgo, A.P.4    Granja, P.L.5    Tomás, H.6
  • 58
    • 77953239685 scopus 로고    scopus 로고
    • Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
    • Santos J.L., Oliveira H., Pandita D., Rodrigues J., Pêgo A.P., Granja P.L., Tomás H. Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells. J. Control. Rel. 2010, 144:55-64.
    • (2010) J. Control. Rel. , vol.144 , pp. 55-64
    • Santos, J.L.1    Oliveira, H.2    Pandita, D.3    Rodrigues, J.4    Pêgo, A.P.5    Granja, P.L.6    Tomás, H.7
  • 60
    • 84877060631 scopus 로고    scopus 로고
    • Targeted CT/MR dual mode imaging of tumors using multifunctional dendrimer-entrapped gold nanoparticles
    • Chen Q., Li K., Wen S., Liu H., Peng C., Cai H., Shen M., Zhang G., Shi X. Targeted CT/MR dual mode imaging of tumors using multifunctional dendrimer-entrapped gold nanoparticles. Biomaterials 2013, 34:5200-5209.
    • (2013) Biomaterials , vol.34 , pp. 5200-5209
    • Chen, Q.1    Li, K.2    Wen, S.3    Liu, H.4    Peng, C.5    Cai, H.6    Shen, M.7    Zhang, G.8    Shi, X.9
  • 61
    • 84900875046 scopus 로고    scopus 로고
    • Lactobionic acid-modified dendrimer-entrapped gold nanoparticles for targeted computed tomography imaging of human hepatocellular carcinoma
    • Liu H., Wang H., Xu Y., Guo R., Wen S., Huang Y., Liu W., Shen M., Zhao J., Zhang G., Shi X. Lactobionic acid-modified dendrimer-entrapped gold nanoparticles for targeted computed tomography imaging of human hepatocellular carcinoma. ACS Appl. Mater. Interfaces 2014, 6:6944-6953.
    • (2014) ACS Appl. Mater. Interfaces , vol.6 , pp. 6944-6953
    • Liu, H.1    Wang, H.2    Xu, Y.3    Guo, R.4    Wen, S.5    Huang, Y.6    Liu, W.7    Shen, M.8    Zhao, J.9    Zhang, G.10    Shi, X.11
  • 63
    • 0038407494 scopus 로고    scopus 로고
    • Microscopic protonation equilibria of poly(amidoamine) dendrimers from macroscopic titrations
    • Cakara D., Kleimann J., Borkovec M. Microscopic protonation equilibria of poly(amidoamine) dendrimers from macroscopic titrations. Macromolecules 2003, 36:4201-4207.
    • (2003) Macromolecules , vol.36 , pp. 4201-4207
    • Cakara, D.1    Kleimann, J.2    Borkovec, M.3
  • 64
    • 68149138309 scopus 로고    scopus 로고
    • Host-guest chemistry of dendrimer-drug complexes. 2. Effects of molecular properties of guests and surface functionalities of dendrimers
    • Hu J., Cheng Y., Wu Q., Zhao L., Xu T. Host-guest chemistry of dendrimer-drug complexes. 2. Effects of molecular properties of guests and surface functionalities of dendrimers. J. Phys. Chem. B 2009, 113:10650-10659.
    • (2009) J. Phys. Chem. B , vol.113 , pp. 10650-10659
    • Hu, J.1    Cheng, Y.2    Wu, Q.3    Zhao, L.4    Xu, T.5
  • 65
    • 0034511706 scopus 로고    scopus 로고
    • Unusual pH-dependent polarity changes in PAMAM dendrimers: evidence for pH-responsive conformational changes
    • Chen W., Tomalia D.A., Thomas J.L. Unusual pH-dependent polarity changes in PAMAM dendrimers: evidence for pH-responsive conformational changes. Macromolecules 2000, 33:9169-9172.
    • (2000) Macromolecules , vol.33 , pp. 9169-9172
    • Chen, W.1    Tomalia, D.A.2    Thomas, J.L.3
  • 66
    • 77954637738 scopus 로고    scopus 로고
    • Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics-the trio of imaging, targeting and therapy
    • Cheng S.-H., Lee C.-H., Chen M.-C., Souris J.S., Tseng F.-G., Yang C.-S., Mou C.-Y., Chen C.-T., Lo L.-W. Tri-functionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics-the trio of imaging, targeting and therapy. J. Mater. Chem. 2010, 20:6149-6157.
    • (2010) J. Mater. Chem. , vol.20 , pp. 6149-6157
    • Cheng, S.-H.1    Lee, C.-H.2    Chen, M.-C.3    Souris, J.S.4    Tseng, F.-G.5    Yang, C.-S.6    Mou, C.-Y.7    Chen, C.-T.8    Lo, L.-W.9


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