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Angewandte Chemie - International Edition

Volumn 51, Issue 50, 2012, Pages 12486-12489

Enzyme-responsive controlled release of covalently bound prodrug from functional mesoporous silica nanospheres

(6) Popat, Amirali a Ross, Benjamin P a Liu, Jian a Jambhrunkar, Siddharth a Kleitz, Freddy b Qiao, Shi Zhang a,c

a UNIVERSITY OF QUEENSLAND (Australia)

b UNIVERSITÉ LAVAL (Canada)

c UNIVERSITY OF ADELAIDE (Australia)

Author keywords

azo reductase; colon targeting; drug delivery; nanoparticles; sulfasalazine

Indexed keywords

AZO-REDUCTASE; COLON TARGETING; CONTROLLED RELEASE; COVALENTLY BOUND; FUNCTIONALIZED; MESOPOROUS SILICA; MESOPOROUS SILICA NANOPARTICLES; NANOCARRIERS; PRODRUGS; SULFAPYRIDINE; SULFASALAZINE;

DRUG DELIVERY; NANOPARTICLES;

ENZYMES;

DRUG CARRIER; MESALAZINE; NANOSPHERE; OXIDOREDUCTASE; PRODRUG; SALAZOSULFAPYRIDINE; SILICON DIOXIDE; SULFAPYRIDINE;

ARTICLE; CHEMISTRY; METABOLISM; PH; POROSITY;

DRUG CARRIERS; HYDROGEN-ION CONCENTRATION; MESALAMINE; NANOSPHERES; OXIDOREDUCTASES; POROSITY; PRODRUGS; SILICON DIOXIDE; SULFAPYRIDINE; SULFASALAZINE;

EID: 84870608086 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201206416 Document Type: Article

Times cited : (154)

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