The thymic cortical epithelium determines the TCR repertoire of IL-17-producing γδT cells

EMBO Reports

Volumn 16, Issue 5, 2015, Pages 638-653

  Nitta, Takeshi ^a   Muro, Ryunosuke ^a   Shimizu, Yukiko ^a   Nitta, Sachiko ^a   Oda, Hiroyo ^a   Ohte, Yuki ^b   Goto, Motohito ^a   Yanobu Takanashi, Rieko ^a   Narita, Tomoya ^c   Takayanagi, Hiroshi ^c   Yasuda, Hisataka ^d   Okamura, Tadashi ^a   Murata, Shigeo ^b   Suzuki, Harumi ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d Oriental Yeast Co Ltd   (Japan)

Author keywords

IL 17; thymic epithelial cell; thymus; 5t; T

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CYTOKERATIN 5; CYTOKERATIN 8; GAMMA INTERFERON; INTERLEUKIN 17; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; SECONDARY LYMPHOID TISSUE CHEMOKINE; SKINT1 PROTEIN; STROMAL CELL DERIVED FACTOR 1; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR SOX13; UEA1 PROTEIN; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEASOME;

ADULT; ALPHA BETA T LYMPHOCYTE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BONE MARROW CELL; CD3+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CONTACT; CELL MATURATION; CHROMOSOME 14; CODON; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EPITHELIUM CELL; FETUS; GAMMA DELTA T LYMPHOCYTE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LINKAGE ANALYSIS; LIVER; LYMPHOCYTE DIFFERENTIATION; MISSENSE MUTATION; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PHENOTYPE; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SPLEEN; STROMA CELL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; THYMIC EPITHELIUM CELL; THYMUS; YOUNG ADULT; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL SURVIVAL; CYTOLOGY; DNA MUTATIONAL ANALYSIS; EPITHELIUM; FEMALE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; THYMOCYTE; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL SURVIVAL; DNA MUTATIONAL ANALYSIS; EPITHELIAL CELLS; EPITHELIUM; FEMALE; INFLAMMATION; INTERLEUKIN-17; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; NATURAL KILLER T-CELLS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; THYMOCYTES; THYMUS GLAND;

EID: 84928929394     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540096     Document Type: Article

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